The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 1LIFE HEALTHCARE INC | COM | 68269G107 | 3,153,748 | 183,892 | SH | DFND | 13, 15 | 183,892 | 0 | 0 | ||
| AIRBNB INC | COM CL A | 009066101 | 242,641,665 | 2,309,993 | SH | DFND | 7, 27, 28 | 2,309,993 | 0 | 0 | ||
| AKILI INC | COMMON STOCK | 00974B107 | 26,010,616 | 11,509,122 | SH | DFND | 14, 26, 29 | 11,509,122 | 0 | 0 | ||
| ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 736,787,650 | 9,210,997 | SH | DFND | 2, 22, 23, 25 | 9,210,997 | 0 | 0 | ||
| ALVOTECH | ORDINARY SHARES | L01800108 | 6,760,000 | 1,000,000 | SH | DFND | 5, 13 | 1,000,000 | 0 | 0 | ||
| AMAZON COM INC | COM | 023135106 | 356,453,980 | 3,154,460 | SH | DFND | 2, 11, 22, 25 | 3,154,460 | 0 | 0 | ||
| ASLAN PHARMACEUTICALS LTD | ADS | 04522R101 | 1,004,664 | 1,678,075 | SH | DFND | 2, 14, 22, 25, 26, 31 | 1,678,075 | 0 | 0 | ||
| BEAM THERAPEUTICS INC | COM | 07373V105 | 136,549,008 | 2,866,268 | SH | DFND | 13, 14, 15, 26, 29, 31 | 2,866,268 | 0 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 419,286,155 | 3,109,970 | SH | DFND | 2, 14, 16, 22, 25, 26, 31 | 3,109,970 | 0 | 0 | ||
| BILL COM HLDGS INC | COM | 090043100 | 744,997,024 | 5,628,141 | SH | DFND | 13, 14, 15, 16, 20, 22, 25 | 5,628,141 | 0 | 0 | ||
| BIONTECH SE | SPONSORED ADS | 09075V102 | 590,507,607 | 4,378,022 | SH | DFND | 3, 9, 27 | 4,378,022 | 0 | 0 | ||
| BLACKROCK INC | COM | 09247X101 | 2,802,479,741 | 5,092,825 | SH | DFND | 2, 10, 22, 25, 27 | 5,092,825 | 0 | 0 | ||
| BLACKSTONE INC | COM | 09260D107 | 63,036,981 | 753,130 | SH | DFND | 14, 17 | 753,130 | 0 | 0 | ||
| BLEND LABS INC | CL A | 09352U108 | 26,245,458 | 11,875,773 | SH | DFND | 14, 16, 20 | 11,875,773 | 0 | 0 | ||
| COHERUS BIOSCIENCES INC | COM | 19249H103 | 70,932,525 | 7,381,116 | SH | DFND | 14, 26, 31 | 7,381,116 | 0 | 0 | ||
| CUE HEALTH INC | COM | 229790100 | 9,406,250 | 3,125,000 | SH | DFND | 14, 26, 31 | 3,125,000 | 0 | 0 | ||
| DATADOG INC | CL A COM | 23804L103 | 6,615,797 | 74,519 | SH | DFND | 13, 15 | 74,519 | 0 | 0 | ||
| DELL TECHNOLOGIES INC | CL C | 24703L202 | 302,341,183 | 8,848,147 | SH | DFND | 19, 27, 30 | 8,848,147 | 0 | 0 | ||
| DENALI THERAPEUTICS INC | COM | 24823R105 | 171,128,698 | 5,576,041 | SH | DFND | 14, 22, 25, 26, 29, 31 | 5,576,041 | 0 | 0 | ||
| DOORDASH INC | CL A | 25809K105 | 242,070,409 | 4,895,256 | SH | DFND | 2, 7, 13, 15, 22, 25, 27, 28 | 4,895,256 | 0 | 0 | ||
| DUCK CREEK TECHNOLOGIES INC | SHS | 264120106 | 43,379,307 | 3,660,701 | SH | DFND | 2, 5, 13, 22, 25 | 3,660,701 | 0 | 0 | ||
| E2OPEN PARENT HOLDINGS INC | COM CL A | 29788T103 | 177,536,277 | 29,248,151 | SH | DFND | 2, 22, 25 | 29,248,151 | 0 | 0 | ||
| FLYWIRE CORPORATION | COM VTG | 302492103 | 244,192,756 | 10,635,573 | SH | DFND | 14, 16, 20 | 10,635,573 | 0 | 0 | ||
| FORGE GLOBAL HOLDINGS INC | COM | 34629L103 | 15,063,496 | 8,607,712 | SH | DFND | 14, 16, 20 | 8,607,712 | 0 | 0 | ||
| GOGORO INC | ORDINARY SHARES | G9491K105 | 30,169,331 | 8,002,475 | SH | DFND | 1, 2, 22, 25, 27, 28 | 8,002,475 | 0 | 0 | ||
| GRAB HOLDINGS LIMITED | CLASS A ORD | G4124C109 | 26,300,000 | 10,000,000 | SH | DFND | 11, 25 | 10,000,000 | 0 | 0 | ||
| GRACELL BIOTECHNOLOGIES INC | SPONSORED ADS | 38406L103 | 31,884,247 | 9,901,940 | SH | DFND | 14, 26, 29 | 9,901,940 | 0 | 0 | ||
| GUARDANT HEALTH INC | COM | 40131M109 | 87,247,072 | 1,620,789 | SH | DFND | 14, 22, 25, 26, 29 | 1,620,789 | 0 | 0 | ||
| HDFC BANK LTD | SPONSORED ADS | 40415F101 | 284,781,843 | 4,874,732 | SH | DFND | 2, 11, 22, 25 | 4,874,732 | 0 | 0 | ||
| HOMOLOGY MEDICINES INC | COM | 438083107 | 9,098,104 | 5,650,996 | SH | DFND | 14, 26, 29, 31 | 5,650,996 | 0 | 0 | ||
| I MAB | SPONSORED ADS | 44975P103 | 2,272,267 | 566,650 | SH | DFND | 2, 22, 25 | 566,650 | 0 | 0 | ||
| ICICI BANK LIMITED | ADR | 45104G104 | 476,736,006 | 22,734,192 | SH | DFND | 2, 6, 11, 14, 22, 25 | 22,734,192 | 0 | 0 | ||
| ILLUMINA INC | COM | 452327109 | 10,579,687 | 55,452 | SH | DFND | 2, 22, 25 | 55,452 | 0 | 0 | ||
| INFOSYS LTD | SPONSORED ADR | 456788108 | 907,352 | 53,468 | SH | DFND | 11, 25 | 53,468 | 0 | 0 | ||
| INTAPP INC | COM | 45827U109 | 413,227,647 | 22,133,243 | SH | DFND | 1, 2, 22, 25, 27, 28 | 22,133,243 | 0 | 0 | ||
| INTELLIA THERAPEUTICS INC | COM | 45826J105 | 11,431,285 | 204,276 | SH | DFND | 11, 25 | 204,276 | 0 | 0 | ||
| IRONNET INC | COM | 46323Q105 | 1,953,515 | 2,831,181 | SH | DFND | 27, 28 | 2,831,181 | 0 | 0 | ||
| ISHARES TR | 0-5 YR TIPS ETF | 46429B747 | 69,103,090 | 719,000 | SH | DFND | 2, 22, 25 | 719,000 | 0 | 0 | ||
| ISHARES GOLD TR | ISHARES NEW | 464285204 | 228,850,636 | 7,258,187 | SH | DFND | 2, 22, 25 | 7,258,187 | 0 | 0 | ||
| ISHARES TR | US TREAS BD ETF | 46429B267 | 401,495,322 | 17,640,392 | SH | DFND | 2, 22, 25 | 17,640,392 | 0 | 0 | ||
| JD.COM INC | SPON ADR CL A | 47215P106 | 8,742,140 | 173,800 | SH | DFND | 2, 22, 25 | 173,800 | 0 | 0 | ||
| KARUNA THERAPEUTICS INC | COM | 48576A100 | 9,244,173 | 41,098 | SH | DFND | 13, 15 | 41,098 | 0 | 0 | ||
| KEURIG DR PEPPER INC | COM | 49271V100 | 3,575,015 | 99,805 | SH | DFND | 13, 15 | 99,805 | 0 | 0 | ||
| KRANESHARES TR | CSI CHI INTERNET | 500767306 | 22,259,283 | 903,380 | SH | DFND | 2, 22, 25 | 903,380 | 0 | 0 | ||
| LUMEN TECHNOLOGIES INC | COM | 550241103 | 518,906,403 | 71,278,352 | SH | DFND | 3, 9, 12, 27 | 71,278,352 | 0 | 0 | ||
| MARQETA INC | CLASS A COM | 57142B104 | 4,552,521 | 639,399 | SH | DFND | 13, 15 | 639,399 | 0 | 0 | ||
| MASTERCARD INCORPORATED | CL A | 57636Q104 | 643,336,310 | 2,262,560 | SH | DFND | 2, 14, 17, 22, 25 | 2,262,560 | 0 | 0 | ||
| MSCI INC | COM | 55354G100 | 45,583,689 | 108,072 | SH | DFND | 2, 22, 25 | 108,072 | 0 | 0 | ||
| NU HLDGS LTD | ORD SHS CL A | G6683N103 | 3,662,151 | 832,307 | SH | DFND | 13, 15 | 832,307 | 0 | 0 | ||
| NVIDIA CORPORATION | COM | 67066G104 | 67,833,946 | 558,810 | SH | DFND | 22, 25 | 558,810 | 0 | 0 | ||
| OPENDOOR TECHNOLOGIES INC | COM | 683712103 | 886,384 | 285,011 | SH | DFND | 13, 15 | 285,011 | 0 | 0 | ||
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 2,159,525 | 4,319,049 | SH | DFND | 14, 26, 29, 31 | 4,319,049 | 0 | 0 | ||
| PAYONEER GLOBAL INC | COM | 70451X104 | 122,464,602 | 20,242,083 | SH | DFND | 5, 13 | 20,242,083 | 0 | 0 | ||
| PAYPAL HLDGS INC | COM | 70450Y103 | 817,904,705 | 9,502,785 | SH | DFND | 2, 14, 17, 22, 24, 25 | 9,502,785 | 0 | 0 | ||
| PEAR THERAPEUTICS INC | CLASS A COM | 704723105 | 54,679,289 | 26,803,573 | SH | DFND | 14, 26, 29 | 26,803,573 | 0 | 0 | ||
| PINDUODUO INC | SPONSORED ADS | 722304102 | 169,972,349 | 2,716,081 | SH | DFND | 2, 14, 16, 22, 25 | 2,716,081 | 0 | 0 | ||
| RENT THE RUNWAY INC | COM CL A | 76010Y103 | 1,605,234 | 729,652 | SH | DFND | 13 | 729,652 | 0 | 0 | ||
| ROBINHOOD MKTS INC | COM CL A | 770700102 | 983,942 | 97,420 | SH | DFND | 13, 15 | 97,420 | 0 | 0 | ||
| ROBLOX CORP | CL A | 771049103 | 407,305,185 | 11,364,542 | SH | DFND | 1, 2, 13, 15, 22, 25, 27, 28 | 11,364,542 | 0 | 0 | ||
| S&P GLOBAL INC | COM | 78409V104 | 553,159,846 | 1,811,560 | SH | DFND | 10,27 | 1,811,560 | 0 | 0 | ||
| SCHWAB STRATEGIC TR | US TIPS ETF | 808524870 | 344,724,286 | 6,654,909 | SH | DFND | 2, 22, 25 | 6,654,909 | 0 | 0 | ||
| SEA LTD | SPONSORD ADS | 81141R100 | 173,582,702 | 3,096,926 | SH | DFND | 2, 11, 22, 25 | 3,096,926 | 0 | 0 | ||
| SES AI CORPORATION | CL A COM | 78397Q109 | 169,217,694 | 34,675,757 | SH | DFND | 1, 2, 22, 25, 27, 28 | 34,675,757 | 0 | 0 | ||
| SILVERGATE CAP CORP | CL A | 82837P408 | 7,378,423 | 97,922 | SH | DFND | 27 | 97,922 | 0 | 0 | ||
| SINGULAR GENOMICS SYSTEMS IN | COM | 82933R100 | 53,513 | 21,405 | SH | DFND | 13, 15 | 21,405 | 0 | 0 | ||
| SNOWFLAKE INC | CL A | 833445109 | 246,034,436 | 1,447,602 | SH | DFND | 2, 11, 13, 15, 22, 25 | 1,447,602 | 0 | 0 | ||
| SPRINKLR INC | CL A | 85208T107 | 1,339,371 | 145,268 | SH | DFND | 13, 15 | 145,268 | 0 | 0 | ||
| SQZ BIOTECHNOLOGIES CO | COM | 78472W104 | 6,288,625 | 2,758,169 | SH | DFND | 14, 26, 31 | 2,758,169 | 0 | 0 | ||
| STEM INC | COM | 85859N102 | 5,501,736 | 412,424 | SH | DFND | 10,27 | 412,424 | 0 | 0 | ||
| STONECO LTD | COM CL A | G85158106 | 11,768,121 | 1,234,850 | SH | DFND | 11, 25 | 1,234,850 | 0 | 0 | ||
| THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 510,102,285 | 1,005,742 | SH | DFND | 6, 14, 18, 26, 31 | 1,005,742 | 0 | 0 | ||
| TOAST INC | CL A | 888787108 | 19,395,016 | 1,159,989 | SH | DFND | 21, 22, 25 | 1,159,989 | 0 | 0 | ||
| TPG INC | COM CL A | 872657101 | 145,331,983 | 5,220,258 | SH | DFND | 14, 26, 31 | 5,220,258 | 0 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 654,528 | 27,272 | SH | DFND | 13, 15 | 27,272 | 0 | 0 | ||
| VERVE THERAPEUTICS INC | COM | 92539P101 | 943,114 | 27,456 | SH | DFND | 13, 15 | 27,456 | 0 | 0 | ||
| VIR BIOTECHNOLOGY INC | COM | 92764N102 | 116,389,909 | 6,036,821 | SH | DFND | 13, 14, 15, 22, 25, 26, 29, 31 | 6,036,821 | 0 | 0 | ||
| VIRTU FINL INC | CL A | 928254101 | 76,689,694 | 3,692,330 | SH | DFND | 13, 15 | 3,692,330 | 0 | 0 | ||
| VISA INC | COM CL A | 92826C839 | 1,021,485,013 | 5,749,986 | SH | DFND | 2, 14, 17, 22, 25 | 5,749,986 | 0 | 0 | ||
| VMWARE INC | CL A COM | 928563402 | 486,878,415 | 4,573,346 | SH | DFND | 11, 19, 25, 27, 30 | 4,573,346 | 0 | 0 | ||
| YUM CHINA HLDGS INC | COM | 98850P109 | 86,278,094 | 1,822,905 | SH | DFND | 2, 7, 14, 16, 22, 25, 27, 28 | 1,822,905 | 0 | 0 | ||
| ZTO EXPRESS CAYMAN INC | SPONSORED ADS A | 98980A105 | 292,607,303 | 12,176,750 | SH | DFND | 2, 22, 25 | 12,176,750 | 0 | 0 | ||