The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | BBG00YV1J631 | 49,493,945 | 4,890,706 | SH | SOLE | 4,890,706 | 0 | 0 | ||
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | BBG001SD42R0 | 14,280,000 | 12,000,000 | SH | SOLE | 12,000,000 | 0 | 0 | ||
| ARGENX SE | SPONSORED ADR | 04016X101 | BBG00GHB88Y8 | 71,827,239 | 184,300 | SH | Put | SOLE | 184,300 | 0 | 0 | |
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | BBG001S7K151 | 20,051,307 | 2,848,197 | SH | SOLE | 2,848,197 | 0 | 0 | ||
| BURNING ROCK BIOTECH LTD | SPONSORED ADS | 12233L107 | BBG00V1JWFQ1 | 18,309,473 | 8,500,000 | SH | SOLE | 8,500,000 | 0 | 0 | ||
| CATALYST BIOSCIENCES INC | COM NEW | 14888D208 | BBG001SDL5X7 | 31,604 | 89,886 | SH | SOLE | 89,886 | 0 | 0 | ||
| CELLDEX THERAPEUTICS INC NEW | COM NEW | 15117B202 | BBG001S7QN20 | 88,218,000 | 2,600,000 | SH | SOLE | 2,600,000 | 0 | 0 | ||
| CENTESSA PHARMACEUTICALS PLC | SPONSORED ADS | 152309100 | BBG01081FC68 | 4,512,987 | 729,077 | SH | SOLE | 729,077 | 0 | 0 | ||
| COGENT BIOSCIENCES INC | COM | 19240Q201 | BBG007DHY102 | 19,149,909 | 1,617,391 | SH | SOLE | 1,617,391 | 0 | 0 | ||
| CONNECT BIOPHARMA HLDGS LTD | ADS | 207523101 | BBG00ZGYNJZ5 | 602,640 | 535,005 | SH | SOLE | 535,005 | 0 | 0 | ||
| FIBROGEN INC | COM | 31572Q808 | BBG001SN7DS0 | 1,583,550 | 586,500 | SH | Call | SOLE | 586,500 | 0 | 0 | |
| LIQUIDIA CORPORATION | COM NEW | 53635D202 | BBG001V0GFD7 | 12,891,615 | 1,642,244 | SH | SOLE | 1,642,244 | 0 | 0 | ||
| NATERA INC | COM | 632307104 | BBG001V0FSF8 | 141,114,000 | 2,900,000 | SH | SOLE | 2,900,000 | 0 | 0 | ||
| NEOLEUKIN THERAPEUTICS INC | COM | 64049K104 | BBG005Y0QF99 | 99,572 | 119,966 | SH | SOLE | 119,966 | 0 | 0 | ||
| OLEMA PHARMACEUTICALS INC | COM | 68062P106 | BBG00T5JMRV1 | 11,778,118 | 1,304,332 | SH | SOLE | 1,304,332 | 0 | 0 | ||
| PROTAGONIST THERAPEUTICS INC | COM | 74366E102 | BBG002B63KP4 | 26,937,731 | 975,298 | SH | SOLE | 975,298 | 0 | 0 | ||
| PTC THERAPEUTICS INC | COM | 69366J200 | BBG001SNNC86 | 1,159,095 | 28,500 | SH | Call | SOLE | 28,500 | 0 | 0 | |
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | BBG001TFZB81 | 1,669,937 | 473,070 | SH | SOLE | 473,070 | 0 | 0 | ||
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | BBG007DLZ629 | 1,527,007 | 92,602 | SH | SOLE | 92,602 | 0 | 0 | ||
| SUTRO BIOPHARMA INC | COM | 869367102 | BBG001T94MP6 | 6,975,000 | 1,500,000 | SH | SOLE | 1,500,000 | 0 | 0 | ||
| SYNDAX PHARMACEUTICALS INC | COM | 87164F105 | BBG001T92272 | 68,273,744 | 3,262,004 | SH | SOLE | 3,262,004 | 0 | 0 | ||
| TRAVERE THERAPEUTICS INC | COM | 89422G107 | BBG001SL72C5 | 22,344,653 | 1,454,730 | SH | SOLE | 1,454,730 | 0 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | BBG009PHHPP4 | 64,922,000 | 1,300,000 | SH | SOLE | 1,300,000 | 0 | 0 | ||
| VERA THERAPEUTICS INC | CL A | 92337R101 | BBG00Q72WYH2 | 48,150,000 | 3,000,000 | SH | SOLE | 3,000,000 | 0 | 0 | ||
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | BBG002H24301 | 16,878,957 | 709,498 | SH | SOLE | 709,498 | 0 | 0 | ||
| WAVE LIFE SCIENCES LTD | SHS | Y95308105 | BBG00B642V63 | 14,285,551 | 3,924,602 | SH | SOLE | 3,924,602 | 0 | 0 | ||