The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | |||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | ||||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | FIGI | (to the nearest dollar) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2SEVENTY BIO INC | COMMON STOCK | 901384107 | 2,530,000 | 250,000 | SH | OTR | 1 | 0 | 250,000 | 0 | ||
| 908 DEVICES INC | COM | 65443P102 | 686,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| ACELRX PHARMACEUTICALS INC | COM NEW | 00444T209 | 216,450 | 195,000 | SH | OTR | 1 | 0 | 195,000 | 0 | ||
| ADAPTIMMUNE THERAPEUTICS PLC | SPONDS ADR | 00653A107 | 4,520,695 | 4,887,238 | SH | OTR | 1 | 0 | 4,887,238 | 0 | ||
| ADICET BIO INC | COM | 007002108 | 6,025,311 | 2,479,552 | SH | OTR | 1 | 0 | 2,479,552 | 0 | ||
| ADMA BIOLOGICS INC | COM | 000899104 | 4,649,400 | 1,260,000 | SH | OTR | 1 | 0 | 1,260,000 | 0 | ||
| ALIGOS THERAPEUTICS INC | COM | 01626L105 | 3,232,506 | 3,329,048 | SH | OTR | 1 | 0 | 3,329,048 | 0 | ||
| ALTIMMUNE INC | COM NEW | 02155H200 | 9,707,500 | 2,750,000 | SH | OTR | 1 | 0 | 2,750,000 | 0 | ||
| AMARIN CORP PLC | SPONS ADR NEW | 023111206 | 8,449,000 | 7,100,000 | SH | OTR | 1 | 0 | 7,100,000 | 0 | ||
| AMYLYX PHARMACEUTICALS INC | COM | 03237H101 | 2,157,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| ANAPTYSBIO INC | COM | 032724106 | 39,675,387 | 1,950,609 | SH | OTR | 1 | 0 | 1,950,609 | 0 | ||
| ARS PHARMACEUTICALS INC | COM | 82835W108 | 2,743,402 | 409,463 | SH | OTR | 1 | 0 | 409,463 | 0 | ||
| ARVINAS INC | COM | 04335A105 | 1,985,600 | 80,000 | SH | OTR | 1 | 0 | 80,000 | 0 | ||
| ASCENDIS PHARMA A/S | SPONSORED ADR | 04351P101 | 892,500 | 10,000 | SH | OTR | 1 | 0 | 10,000 | 0 | ||
| ASLAN PHARMACEUTICALS LTD | SPON ADS NEW | 04522R200 | 4,117,448 | 1,128,068 | SH | OTR | 1 | 0 | 1,128,068 | 0 | ||
| ASTRAZENECA PLC | SPONSORED ADR | 046353108 | 12,166,900 | 170,000 | SH | OTR | 1 | 0 | 170,000 | 0 | ||
| ATEA PHARMACEUTICALS INC | COM | 04683R106 | 11,318,942 | 3,026,455 | SH | OTR | 1 | 0 | 3,026,455 | 0 | ||
| ATHIRA PHARMA INC | COM | 04746L104 | 1,040,509 | 352,715 | SH | OTR | 1 | 0 | 352,715 | 0 | ||
| ATYR PHARMA INC | COM NEW | 002120202 | 324,000 | 150,000 | SH | OTR | 1 | 0 | 150,000 | 0 | ||
| AURINIA PHARMACEUTICALS INC | COM | 05156V102 | 1,452,000 | 150,000 | SH | OTR | 1 | 0 | 150,000 | 0 | ||
| AVROBIO INC | COM | 05455M100 | 2,570,021 | 2,705,000 | SH | OTR | 1 | 0 | 2,705,000 | 0 | ||
| AXSOME THERAPEUTICS INC | COM | 05464T104 | 22,995,200 | 320,000 | SH | OTR | 1 | 0 | 320,000 | 0 | ||
| BANK HAWAII CORP | COM | 062540109 | 1,236,900 | 30,000 | SH | OTR | 1 | 0 | 30,000 | 0 | ||
| BANKUNITED INC | COM | 06652K103 | 2,155,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| BEIGENE LTD | SPONSORED ADR | 07725L102 | 15,155,500 | 85,000 | SH | OTR | 1 | 0 | 85,000 | 0 | ||
| BIO RAD LABS INC | CL A | 090572207 | 6,065,920 | 16,000 | SH | OTR | 1 | 0 | 16,000 | 0 | ||
| BIOATLA INC | COM | 09077B104 | 11,022,228 | 3,674,076 | SH | OTR | 1 | 0 | 3,674,076 | 0 | ||
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 17,248,000 | 2,450,000 | SH | OTR | 1 | 0 | 2,450,000 | 0 | ||
| BIOHAVEN LTD | COM | G1110E107 | 3,348,800 | 140,000 | SH | OTR | 1 | 0 | 140,000 | 0 | ||
| BLUEBIRD BIO INC | COM | 09609G100 | 24,289,501 | 7,382,827 | SH | OTR | 1 | 0 | 7,382,827 | 0 | ||
| BOLT BIOTHERAPEUTICS INC | COM | 097702104 | 4,267,268 | 3,333,803 | SH | OTR | 1 | 0 | 3,333,803 | 0 | ||
| CAPITAL ONE FINL CORP | COM | 14040H105 | 8,749,600 | 80,000 | SH | OTR | 1 | 0 | 80,000 | 0 | ||
| CITIGROUP INC | COM NEW | 172967424 | 4,604,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| COHERUS BIOSCIENCES INC | COM | 19249H103 | 1,708,000 | 400,000 | SH | OTR | 1 | 0 | 400,000 | 0 | ||
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 1,122,800 | 20,000 | SH | OTR | 1 | 0 | 20,000 | 0 | ||
| CYTOMX THERAPEUTICS INC | COM | 23284F105 | 11,352,000 | 6,600,000 | SH | OTR | 1 | 0 | 6,600,000 | 0 | ||
| CULLINAN ONCOLOGY INC | COM | 230031106 | 4,842,000 | 450,000 | SH | OTR | 1 | 0 | 450,000 | 0 | ||
| CVB FINL CORP | COM | 126600105 | 2,656,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| DYNAVAX TECHNOLOGIES CORP | COM NEW | 268158201 | 3,876,000 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| EAGLE PHARMACEUTICALS INC | COM | 269796108 | 2,310,580 | 118,857 | SH | OTR | 1 | 0 | 118,857 | 0 | ||
| EDITAS MEDICINE INC | COM | 28106W103 | 1,646,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| ELEVATION ONCOLOGY INC | COM | 28623U101 | 6,080,000 | 4,000,000 | SH | OTR | 1 | 0 | 4,000,000 | 0 | ||
| ENZO BIOCHEM INC | COM | 294100102 | 4,232,000 | 2,300,000 | SH | OTR | 1 | 0 | 2,300,000 | 0 | ||
| EQUILLIUM INC | COM | 29446K106 | 300,000 | 400,000 | SH | OTR | 1 | 0 | 400,000 | 0 | ||
| EQUITY COMWLTH | COM SH BEN INT | 294628102 | 2,026,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| ESPERION THERAPEUTICS INC NE | COM | 29664W105 | 2,571,500 | 1,850,000 | SH | OTR | 1 | 0 | 1,850,000 | 0 | ||
| EVOLUS INC | COM | 30052C107 | 22,518,091 | 3,097,399 | SH | OTR | 1 | 0 | 3,097,399 | 0 | ||
| FATE THERAPEUTICS INC | COM | 31189P102 | 3,332,000 | 700,000 | SH | OTR | 1 | 0 | 700,000 | 0 | ||
| FREELINE THERAPEUTICS HLDGS | SPONSORED ADS | 35655L206 | 258,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| GALAPAGOS NV | SPON ADR | 36315X101 | 3,645,169 | 89,650 | SH | OTR | 1 | 0 | 89,650 | 0 | ||
| GENEDX HOLDINGS CORP | COM CL A | 81663L200 | 379,273 | 63,636 | SH | OTR | 1 | 0 | 63,636 | 0 | ||
| GENFIT S A | ADS | 372279109 | 4,369,903 | 1,234,436 | SH | OTR | 1 | 0 | 1,234,436 | 0 | ||
| GRAPHITE BIO INC | COM | 38870X104 | 5,422,625 | 2,085,625 | SH | OTR | 1 | 0 | 2,085,625 | 0 | ||
| HARMONY BIOSCIENCES HLDGS IN | COM | 413197104 | 9,543,528 | 271,200 | SH | OTR | 1 | 0 | 271,200 | 0 | ||
| HERON THERAPEUTICS INC | COM | 427746102 | 2,146,000 | 1,850,000 | SH | OTR | 1 | 0 | 1,850,000 | 0 | ||
| IMMUNOCORE HLDGS PLC | ADS | 45258D105 | 24,319,776 | 405,600 | SH | OTR | 1 | 0 | 405,600 | 0 | ||
| IMMUNOGEN INC | COM | 45253H101 | 24,531,000 | 1,300,000 | SH | OTR | 1 | 0 | 1,300,000 | 0 | ||
| INFLARX NV | COM | N44821101 | 12,934,000 | 2,900,000 | SH | OTR | 1 | 0 | 2,900,000 | 0 | ||
| INSMED INC | COM PAR $.01 | 457669307 | 3,506,883 | 166,203 | SH | OTR | 1 | 0 | 166,203 | 0 | ||
| INSPIRATO INCORPORATED | COM CL A | 45791E107 | 1,014,300 | 1,035,000 | SH | OTR | 1 | 0 | 1,035,000 | 0 | ||
| INTRA-CELLULAR THERAPIES INC | COM | 46116X101 | 18,996,000 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| INVIVYD INC | COM | 00534A102 | 1,209,435 | 1,151,843 | SH | OTR | 1 | 0 | 1,151,843 | 0 | ||
| IONIS PHARMACEUTICALS INC | COM | 462222100 | 8,206,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| KALVISTA PHARMACEUTICALS INC | COM | 483497103 | 23,862,537 | 2,651,393 | SH | OTR | 1 | 0 | 2,651,393 | 0 | ||
| KINIKSA PHARMACEUTICALS LTD | COM CL A | G5269C101 | 8,448,000 | 600,000 | SH | OTR | 1 | 0 | 600,000 | 0 | ||
| LIANBIO | SPONSORED ADS | 53000N108 | 2,193,410 | 962,022 | SH | OTR | 1 | 0 | 962,022 | 0 | ||
| LILLY ELI & CO | COM | 532457108 | 14,069,400 | 30,000 | SH | OTR | 1 | 0 | 30,000 | 0 | ||
| MAGENTA THERAPEUTICS INC | COM | 55910K108 | 4,593,480 | 6,060,000 | SH | OTR | 1 | 0 | 6,060,000 | 0 | ||
| MEI PHARMA INC | COM | 55279B301 | 2,375,933 | 361,084 | SH | OTR | 1 | 0 | 361,084 | 0 | ||
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 2,890,400 | 80,000 | SH | OTR | 1 | 0 | 80,000 | 0 | ||
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 29,416,958 | 1,137,107 | SH | OTR | 1 | 0 | 1,137,107 | 0 | ||
| MODERNA INC | COM | 60770K107 | 9,319,050 | 76,700 | SH | OTR | 1 | 0 | 76,700 | 0 | ||
| MOLECULAR PARTNERS AG | ADS | 60853G106 | 247,264 | 39,753 | SH | OTR | 1 | 0 | 39,753 | 0 | ||
| NEKTAR THERAPEUTICS | COM | 640268108 | 80,298 | 139,600 | SH | OTR | 1 | 0 | 139,600 | 0 | ||
| NEURONETICS INC | COM | 64131A105 | 430,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| NEXTCURE INC | COM | 65343E108 | 720,000 | 400,000 | SH | OTR | 1 | 0 | 400,000 | 0 | ||
| NEW YORK CMNTY BANCORP INC | COM | 649445103 | 18,058,184 | 1,606,600 | SH | OTR | 1 | 0 | 1,606,600 | 0 | ||
| NKARTA INC | COM | 65487U108 | 3,034,966 | 1,385,829 | SH | OTR | 1 | 0 | 1,385,829 | 0 | ||
| NOVOCURE LTD | ORD SHS | G6674U108 | 4,150,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| PARDES BIOSCIENCES INC | COM | 69945Q105 | 3,520,823 | 1,945,206 | SH | OTR | 1 | 0 | 1,945,206 | 0 | ||
| PASSAGE BIO INC | COM | 702712100 | 282,390 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| PDS BIOTECHNOLOGY CORP | COM | 70465T107 | 503,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| PHATHOM PHARMACEUTICALS INC | COM | 71722W107 | 3,580,000 | 250,000 | SH | OTR | 1 | 0 | 250,000 | 0 | ||
| PYXIS ONCOLOGY INC | COMMON STOCK | 747324101 | 4,576,704 | 1,787,775 | SH | OTR | 1 | 0 | 1,787,775 | 0 | ||
| QUINCE THERAPEUTICS INC | COM | 22053A107 | 5,437,986 | 3,613,280 | SH | OTR | 1 | 0 | 3,613,280 | 0 | ||
| RAIN ONCOLOGY INC | COM | 75082Q105 | 4,488,409 | 3,740,341 | SH | OTR | 1 | 0 | 3,740,341 | 0 | ||
| SELECTA BIOSCIENCES INC | COM | 816212104 | 448,000 | 400,000 | SH | OTR | 1 | 0 | 400,000 | 0 | ||
| SERVISFIRST BANCSHARES INC | COM | 81768T108 | 1,227,600 | 30,000 | SH | OTR | 1 | 0 | 30,000 | 0 | ||
| SMART POWERR CORP | COM | 168913309 | 202,599 | 125,061 | SH | OTR | 1 | 0 | 125,061 | 0 | ||
| STELLAR BANCORP INC | COM | 858927106 | 457,800 | 20,000 | SH | OTR | 1 | 0 | 20,000 | 0 | ||
| TANGO THERAPEUTICS INC | COM | 87583X109 | 664,000 | 200,000 | SH | OTR | 1 | 0 | 200,000 | 0 | ||
| TARSUS PHARMACEUTICALS INC | COM | 87650L103 | 32,149,385 | 1,779,158 | SH | OTR | 1 | 0 | 1,779,158 | 0 | ||
| THIRD HARMONIC BIO INC | COM | 88427A107 | 8,658,000 | 1,800,000 | SH | OTR | 1 | 0 | 1,800,000 | 0 | ||
| US BANCORP DEL | COM NEW | 902973304 | 3,304,000 | 100,000 | SH | OTR | 1 | 0 | 100,000 | 0 | ||
| VAXCYTE INC | COM | 92243G108 | 14,982,000 | 300,000 | SH | OTR | 1 | 0 | 300,000 | 0 | ||
| VERASTEM INC | COM NEW | 92337C203 | 8,481,600 | 1,140,000 | SH | OTR | 1 | 0 | 1,140,000 | 0 | ||
| VERITEX HLDGS INC | COM | 923451108 | 3,765,300 | 210,000 | SH | OTR | 1 | 0 | 210,000 | 0 | ||
| VIRIDIAN THERAPEUTICS INC | COM | 92790C104 | 16,484,686 | 692,925 | SH | OTR | 1 | 0 | 692,925 | 0 | ||
| ZYMEWORKS DEL INC | COM | 98985Y108 | 9,504,000 | 1,100,000 | SH | OTR | 1 | 0 | 1,100,000 | 0 | ||