Form 10-K

Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes ¨ No x

Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or 15(d) of the Act. Yes ¨ No x

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes x No ¨

Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of registrant’s knowledge, in definitive proxy or information statements incorporated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. ¨

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer or a smaller reporting company. See definitions of “accelerated filer,” “large accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act.

Large Accelerated Filer ¨ Accelerated Filer ¨ Non-Accelerated Filer x Smaller Reporting Company ¨

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Act). Yes ¨ No x

The aggregate market value of the common stock held by non-affiliates of the registrant (based on the closing price for the common stock on the NASDAQ Global Market on June 30, 2008) was approximately $34.5 million. As of March 23, 2009, 53,841,433 shares of the registrant’s common stock, $0.0001 par value, were issued and outstanding.

The information called for by Part III is incorporated by reference to specified portions of the Registrant’s definitive Proxy Statement to be issued in conjunction with the Registrant’s 2009 Annual Meeting of Stockholders, which is expected to be filed not later than 120 days after the Registrant’s fiscal year ended December 31, 2008.

The information in this Annual Report on Form 10-K contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Such statements are based upon current expectations that involve risks and uncertainties. Any statements contained herein that are not statements of historical fact may be deemed to be forward-looking statements. For example, words such as “may,” “will,” “should,” “estimates,” “predicts,” “potential,” “continue,” “strategy,” “believes,” “anticipates,” “plans,” “expects,” “intends,” and similar expressions are intended to identify forward-looking statements. Our actual results and the timing of certain events may differ materially from the results expressed or implied in the forward-looking statement. Factors that might cause or contribute to such a discrepancy include, but are not limited to, those factors discussed in Item 1A, “Risk Factors.” Although we may elect to update forward-looking statements in the future, we specifically disclaim any obligation to do so, even if our estimates change, and readers should not rely on our forward-looking statements as representing our views as of any date subsequent to the date of this Annual Report on Form 10-K.

We provide software and related professional services that allow our clients to manage important aspects of their contractual relationships, including:

We classify our reported revenues into three revenue categories: (i) recurring revenue consists of fees generated from the provision of maintenance, support, and hosting services and subscription revenues; (ii) services revenue is comprised of professional service and training fees and reimbursable out-of-pocket expenses; and (iii) license revenue consists of non-recurring license fees generated from perpetual license agreements. Recurring revenue increased from $19.7 million, or 48.6% of total revenues, in 2007 to $20.5 million, or 59.7% of total revenues, in 2008. Services revenue decreased from $13.5 million, or 33.3% of total revenues, in 2007 to $10.6 million, or 30.7% of total revenues, in 2008. License revenue decreased from $7.3 million, or 18.1% of total revenues, in 2007 to $3.3 million, or 9.6% of total revenues, in 2008. The substantial decreases in services and license revenues in both absolute and relative terms is mostly attributable to a significant decrease in new sales, which we believe was attributable to general economic conditions affecting the life science industries, weak sales execution, a relatively small and recent base of customers using our next generation products and competitive pressures. See “Management’s Discussion and Analysis of Financial Condition and Results of Operations.”

Our clients include supply chain participants on both the “buy” side and “sell” side of business transactions across numerous vertical markets, including manufacturers, distributors, demand aggregators, retailers and purchasers.

We operate our business in two segments: our health and life sciences line of business and our other industries (which we call our “industry solutions”) business. The health and life sciences line of business markets and sells our products and services to companies in the life sciences industries, including pharmaceutical and medical product companies, wholesale distributors, hospitals, group purchasing organizations and managed care organizations. Our industry solutions line of business targets all other industries, with an emphasis on consumer products, foodservice, electronics, service providers, disposables, consumer durables, industrial products, chemicals, energy, apparel, and telecommunications. Our primary products and services were originally developed to manage complex contract purchasing relationships in the health and life sciences industry, and we currently count 19 of the largest 20 worldwide pharmaceutical manufacturers, ranked according to 2007 annual pharmaceutical company revenues, as customers. As the depth and breadth of our product suites have expanded, we have added companies in the industry solutions markets to our customer base. Our customers include Bayer, Eli Lilly, AstraZeneca, GlaxoSmithKline, Novartis Pharmaceuticals, Procter & Gamble, Honeywell Aerospace, RONA, Frito Lay and Dr. Pepper Snapple Group. In 2008, approximately 84.5% of our revenues were from health and life sciences customers and 15.5% of our revenues were from industry solutions sources. See Item 8, Note 9 to Consolidated Financial Statements.

We deliver our products chiefly through two means: (1) software licensed for installation on our clients’ computer systems, and (2) to a lesser extent, software licensed and hosted on our servers, which are operated and supported by third-party providers. While some of our software products are focused solely on customers in our health and life sciences market—I-many Medicaid^TM and I-many Government Pricing^TM, for example—many of our products are applicable to companies in both our industry solutions market and our health and life sciences market. See “Products and Services—Products” below.

In our targeted industries—healthcare and life sciences, consumer products, foodservice, industrial products, chemicals, apparel and other industries where complex purchase contracts exist—the process of creating contracts and identifying and resolving contract compliance issues throughout their life cycle is often accomplished through the use of paper-based or legacy computer systems that are unsuitable for managing the volume and complexity of contracts. In addition, these industries employ pricing mechanisms such as chargebacks and rebates to adjust amounts paid by purchasers. Calculating, reconciling and distributing these chargebacks and rebates while simultaneously ensuring pricing compliance with myriad governmental regulations and other tasks associated with them often result in high administrative costs and disputes involving substantial amounts of money.

Supply chain participants frequently use sales and purchasing contracts to facilitate the purchase and sale of goods and services. These contracts—among supply chain participants, such as manufacturers, distributors, retailers, demand aggregators such as buying groups, and the end users of goods and services—allow buyers and sellers to budget, plan and manage funds and agree on prices, discounts and volume rebates. These contracts often establish price and non-price incentives, which can be based upon multiple factors, including:

In addition to these incentives, contracts can include any number of other attributes, including requirements for fulfilling shipments within prescribed time periods, advanced shipping notifications, packaging and labeling requirements.

Supply Chain Participants. The business-to-business supply chain includes the following participants:

Complexity of Contract Buying/Selling. In the industries we target, contracts typically contain pricing incentives and other mechanisms designed to meet the particular goals of the trading partners. The price of any particular product or service purchased under a typical contract of our customers may vary substantially, depending upon, among other things, external factors such as a manufacturer’s market share and the purchaser’s demographic characteristics, and highly specific factors such as the number of units of a particular product purchased during a specified time period. Contracts also allow buyers and sellers to budget, plan and manage funds and agree on prices, discounts and volume rebates. Training, maintenance and other non-price incentives can also be based upon multiple factors. Other contract attributes include criteria such as a requirement for fulfilling shipments within prescribed time periods, advanced notifications and packaging and labeling requirements. Contracts contain numerous and varied clauses and other business performance language that must also be internally reviewed, approved and managed by both buyers and sellers. Compliance with this language and the individual financial transactions governed by master contracts must be measured in order to ensure the intended outcome of a contract is achieved or to avoid penalties with commercial trading partners or government entities.

Contracts are often negotiated on behalf of a large number of purchasers and include pricing incentives, which result in different prices for otherwise similarly-situated purchasers, based on the purchasers’ achievement of, or failure to achieve, certain goals (usually volume-related) under the contract.

While many purchase contract variations exist, several fundamental types of pricing mechanisms in purchase contracts are illustrative of the complexity involved. Specific examples include chargeback (also called “deviated billing” or “billbacks,” depending upon the industry) and rebate management. Chargebacks are generally used as an incentive tool in contracts between manufacturers and demand aggregators. Eligible members of a demand aggregator (meaning purchasers who are on a contract of the aggregator, such as a group purchasing organization or buying cooperative) order products either directly from the manufacturer or, more commonly, through a large distributor. When a product is ordered through a distributor, the distributor must sell the item at the price negotiated between the manufacturer and the demand aggregator. Often, the manufacturer asks the distributor to sell to the member at a price below the price the distributor paid the manufacturer. In these cases, the distributor attempts to verify the eligibility of the member to receive the lower contract price and, if the purchaser is eligible, the distributor seeks to recover, or chargeback, from the manufacturer the difference

between the distributor’s cost and the lower contract price. Given the large volume of purchases under these contracts, constantly changing membership in demand aggregators, complicated eligibility requirements and disparate information systems involved, it is not uncommon for manufacturers, purchasers, demand aggregators, and distributors to calculate significantly different chargebacks, resulting in disputes among the parties, which require an approved method of adjudication.

A second type of pricing mechanism is a rebate. Typically, rebate provisions entitle a purchaser to a return of a portion of the purchase price based on factors such as the volume of product purchased or increase in market share achieved. Rebate provisions are common in contracts between manufacturers and large volume purchasers. Manufacturers generally adopt this kind of agreement in order to further their marketing objectives. In order to determine rebates based on market share, the parties must refer to external market share data. As with chargeback contracts, the complicated task of administering rebate-based contracts often results in high administrative costs and disputes involving substantial amounts of money.

Many additional mechanisms contained in a purchase contract, sales contract, royalty agreement, or partnering arrangement must also be memorialized and tracked for compliance in order to satisfy contractual commitments or governmental regulations, including the requirements of the Sarbanes-Oxley Act of 2002.

Administrative Demands of Contract Purchasing. As a result of the intricacies of contract purchasing, the administration of sales, purchase and other contracts and agreements can be difficult and expensive. Among other things, each participant in the supply chain may have to:

Broad Offering of Contract Lifecycle Management Capabilities to Serve All Industries. Our products are designed to address business and process needs related to contract management, which in combination we refer to as “Contract LifeCycle Management.” Contract Lifecycle Management provides organizations with the

visibility to ensure compliance and consistency in their contractual relationships. We provide software that allows our clients to optimize their revenue and comply with expenditure limits for critical aspects of their contract-based business-to-business relationships, including:

Broad and Highly Integrated Solutions to Support Life Sciences Contracting. The depth and breadth of I-many’s solution enables the solution of complex problems which are broadly distributed throughout the life sciences industry. These include:

Flexible Product Offerings. We deliver our products through several means. We generally license and deliver our products for installation on our clients’ own computer systems. In addition, we occasionally install software licensed by us on servers hosted and supported by third party providers, which our clients can then access over the Internet or over a secure private network. In 2004 we began to license our solutions as subscriptions, typically for a three to five year term. We believe that these delivery and licensing alternatives provide our clients with flexibility in terms of how they choose to pay for our products, and the level of internal information technology support resources they need to optimize the use.

Products. To date, a significant portion of our revenues has come from the sale of software licenses and related professional services to healthcare manufacturers, distributors, group purchasing organizations and other companies in the life and health sciences customer base. Total net revenue from this customer segment represented 74% of our revenues in 2006, 77% of our revenues in 2007, and 84% of our revenues in 2008. In 2008, no single customer accounted for greater than 10% of total net revenue. Our license fees are based on a number of factors, including the nature and number of modules being licensed, the number of users, the term of the license and the size of the client. For a discussion of our product market segments, see Note 9 to the financial statements contained in Item 8 of this Annual Report on Form 10-K.

The following are brief descriptions of products which are part of I-many ContractSphere^®, and the I-many Revenue Commitment Management Solution Suite. ContractSphere provides the full depth and breadth of I-many’s integrating contracting software solutions and includes:

Professional and Support Services. Our professional services group provides consulting services, deployment services, business analysis services, and training and customer support services. At December 31, 2008, this group was comprised of 66 employees. The group is augmented by outside consultants whom we have trained, working as subcontractors or through strategic relationship agreements.

Approximately 84.5% of our revenue in 2008 was derived from companies in the health and life sciences industries, including pharmaceutical and medical product companies, wholesale distributors and managed care organizations. We also have sold our solutions to companies in other industries such as consumer products, foodservice, disposables, consumer durables, industrial products, chemicals, apparel and others. Revenues from customers based outside the United States, primarily the United Kingdom and the Netherlands, comprised 12%, 7% and 4% of our total revenues in 2006, 2007 and 2008, respectively. At December 31, 2008, 3.7% of our total tangible assets were located outside the United States, primarily in the United Kingdom and India. See Item 8, Note 9 to Consolidated Financial Statements.

We market our software and services primarily through a direct sales force. As of December 31, 2008, our worldwide sales force consisted of a total of 11 employees, including 4 full-time account executives, 1 sales executive who carries an individual quota and has supervision responsibilities, and 6 sales support employees. As of December 31, 2008, we employed 4 marketing employees. We also intend to evaluate the use of third party resellers of our products and services as a supplement to our own direct sales efforts.

As of December 31, 2008, we employed 71 people in our product development organization, which includes 34 employees in our offshore development office in Gandhinagar, India. This group is augmented by outside consultants, most of which are based off-shore. This organization is responsible for the design, development and release of our products. The group is organized into five disciplines: development, quality assurance, documentation, product management and project engineering. Members from each discipline form separate product teams to work closely with our sales, marketing, services, client and prospects organizations to better understand market needs and user requirements. Each product team also hosts a series of user focus groups, and representatives attend our user conference. We also use third parties to expand the capacity and technical expertise of our internal product development organization. Periodically, we have licensed third-party technology and we have acquired companies with products and technologies that are complementary to our existing products. We believe this approach shortens our time to market without compromising our competitive position or product quality, and we plan to continue to draw on third-party resources as needed in the future. Research and development expenses totaled $12.6 million, $15.6 million and $13.6 million, respectively, in 2006, 2007 and 2008.

The contract management software market continues to be subject to rapid change. Competitors vary in size and in the scope and breadth of the products and services offered. We encounter competition primarily from internal information systems departments of potential or current customers that develop custom software, software companies that target the contract management markets, and professional services organizations.

We believe that the principal competitive factors affecting our market include product reputation, functionality, ease-of-use, ability to integrate with other products and technologies, quality, performance, price, customer service and support and the vendors’ reputation. Although we believe that our products currently compete favorably with regard to such factors, we believe competitive pressures contributed to the decrease in our 2008 sales and cannot assure you that we can maintain our competitive position against current and potential competitors. Increased competition may result in price reductions, less beneficial contract terms, reduced gross margins and loss of market share, any of which could materially and adversely affect our business, operating results and financial condition.

Many of our competitors and potential competitors have greater resources than we do, and may be able to respond more quickly and efficiently to new or emerging technologies, programming languages or standards, or to changes in customer requirements or preferences. Many of our competitors can devote greater managerial or financial resources than we can to develop, promote and distribute contract management software products and provide related consulting, training and support services. See “Risk Factors—We have many competitors and potential competitors and we may not be able to compete effectively.”

We rely primarily on a combination of copyright, trademark and trade secrets laws, as well as confidentiality agreements to protect our proprietary rights. Our trademarks include our corporate name and the names of our products. In addition, we have filed applications for patent protection with respect to certain aspects of our products. To date, no patents have been issued to us.

From time to time, we license software from third parties for use with our products. We believe that no such license agreement to which we are presently a party is individually material and that if any such license agreement were to terminate for any reason, we would be able to obtain a license or otherwise acquire other comparable technology or software on terms and on a timetable that would not be materially adverse to us.

As of December 31, 2008, we had a total of 167 employees, of whom 34 were based in Portland, Maine, 38 were based in Redwood City, California, 13 were based at our headquarters in Edison, New Jersey, 4 were based at our international office in London, 34 were based at our offshore development center in Gandhinagar, India, and 44 worked at remote locations. Of the total, 71 were in research and development, 15 were in sales and marketing, 66 were in professional and support services, and 15 were in administration and finance. Our future performance depends in significant part upon the continued service of our key technical, sales and marketing and senior management personnel and our continuing ability to attract and retain highly qualified technical, sales and marketing and managerial personnel. We cannot assure you that we will be successful in attracting or retaining such personnel in the future. None of our employees are represented by a labor union or is subject to a collective bargaining agreement. We have not experienced any work stoppages and consider our relations with our employees to be good.

We were originally incorporated in Massachusetts as Systems Consulting Company, Inc., or SCC, on June 5, 1989. On April 2, 1998, SCC Technologies, Inc., a Delaware corporation, was formed as a holding company and acquired all the stock of SCC. In January 2000, SCC Technologies, Inc. changed its name to

I-many, Inc., and SCC merged into I-many, Inc. Our Internet website address is www.imany.com. We are not including the information contained in our website as part of, or incorporating it by reference into, this Annual Report on Form 10-K. We make available, free of charge through our website, our annual reports on Form 10-K, quarterly reports on Form 10-Q and current reports on Form 8-K, and amendments to these reports, as soon as reasonably practicable after we electronically file these materials with, or otherwise furnish them to, the Securities and Exchange Commission, or SEC.

OUR COMMON STOCK MAY BE DELISTED FROM THE NASDAQ CAPITAL MARKET, WHICH WOULD CAUSE A DEFAULT ON OUR DEBT SECURITIES.

On November 24, 2008, we received notice that our common stock would be delisted from the NASDAQ Capital Market subject to our right to a hearing before a NASDAQ Listing Qualifications Panel (the “Panel”). We requested a hearing and, on January 8, 2009, presented our plan to the Panel for regaining compliance with all applicable requirements for continued listing. On March 20, 2009, the Company received notification from the Panel that it had determined to grant the Company’s request to remain listed on the NASDAQ Capital Market, subject to the condition that, among other things, the Company evidence stockholders’ equity at or above $2.5 million on or before May 26, 2009. The Company is required to provide the Panel with prompt notification of any significant events concerning its ability to regain compliance with NASDAQ’s listing standards, and the Panel reserves the right to reconsider the terms of this exception under circumstances that make continued listing of the Company’s common stock on the NASDAQ Capital Market unwarranted. While the Company is working to regain compliance, there can be no assurance that the Company will be able to regain compliance by the deadline established by the Panel. If our common stock is not listed on any of the NASDAQ Stock Market, the New York Stock Exchange or the NYSE Alternext US Market (formerly the American Stock Exchange) for more than five days, we would be in default on our senior notes sold by the Company on December 31, 2007 in the principal amount of $17 million. The Company has initiated discussions to seek a waiver of this default from the holders of the notes; however, there can be no assurance that it will be able to obtain a waiver on favorable terms, if at all. If the Company is unable to obtain a waiver, it would be in default under the notes and would be unable to repay the notes without raising additional capital and its ability to continue as a going concern would be in significant doubt. See Note 4 to the Financial Statements and “Management’s Discussion and Analysis of Financial Condition and Results of Operations—Liquidity and Capital Resources.”

The ongoing downturn and uncertainty in general economic and market conditions have negatively affected and may continue to negatively affect demand for our products and services. The resulting loss or delay in our sales has had and may continue to have a material adverse effect on our business, financial condition and results of operations.

The Company has substantial indebtedness, including senior notes sold by the Company on December 31, 2007 in the principal amount of $17 million. The payment of interest and principal due under this indebtedness will reduce funds available for other business purposes, including capital expenditures and acquisitions. In addition, the aggregate amount of indebtedness limits the Company’s ability to incur additional indebtedness, and thereby may limit its operations and strategic expansion.

WE HAVE INCURRED SUBSTANTIAL LOSSES IN RECENT YEARS AND OUR RETURN TO PROFITABILITY IS UNCERTAIN

We incurred net losses of $15.8 million, $9.8 million and $15.6 million, respectively, in the years ended December 31, 2006, 2007 and 2008, and we had an accumulated deficit at December 31, 2008 of $175.6 million. We have a stockholders’ deficit of $8.7 million in our balance sheet at December 31, 2008. Our recent results

have been impacted by a number of factors, including decisions by current and prospective customers to defer, or otherwise not make, purchases from us and relatively high research and development expense. Despite our cost restructuring effected in December 2008, we cannot assure you that we will not be affected by these or other factors in future periods. We cannot assure you that we will achieve sufficient revenues to become profitable in the future.

IT IS DIFFICULT FOR US TO PREDICT WHEN OR IF SALES WILL OCCUR AND WHEN WE WILL RECOGNIZE THE REVENUE FROM OUR FUTURE SALES

Our clients view the purchase of our software applications and related professional services as a significant and strategic decision. As a result, clients carefully evaluate our software products and services, often over long periods. Even under ideal economic conditions, the licensing of our software products may be subject to delays if the client has lengthy internal budgeting, approval and evaluation processes, which are quite common in the context of introducing large enterprise-wide technology solutions. The length of this evaluation process varies from client to client. Our clients occasionally license our software on a subscription basis, which results in deferral of payments and revenues that could otherwise be reportable if a traditional, fully-paid perpetual license were executed. Our revenue forecasts and internal budgets are based, in part, on our best assumptions about the mix of future subscription licenses versus perpetual licenses. If we enter into a larger proportion of subscription agreements than planned, we may experience an unplanned shortfall in revenues or cash during that quarter. A significant percentage of our expenses, particularly personnel costs and rent, are fixed costs and are based in part on expectations of future revenues. We may be unable to reduce spending in a timely manner to compensate for any significant fluctuations in revenues and cash. Accordingly, shortfalls in current revenues, as we have experienced in recent years, may cause our operating results to be below the expectations of public market analysts or investors, which could continue to impact the market for our common stock.

OUR CASH FLOW FROM OPERATIONS HAS BEEN NEGATIVE AND MAY CONTINUE TO BE NEGATIVE UNTIL WE RETURN TO SUSTAINED PROFITABILITY, AND WE MAY NEED TO RAISE MORE CASH TO MEET OUR OPERATING NEEDS

Our future long-term capital needs will depend significantly on the rate of growth of our business, our profitability, the mix of subscription licensing arrangements versus perpetual licenses sold, possible acquisitions, the timing of expanded product offerings and the success of these offerings if and when they are launched. Accordingly, our future long-term cash needs and cash flows are subject to uncertainty. If our current balance of cash and cash equivalents is insufficient to satisfy our long-term liquidity needs, we may need to sell additional equity or debt securities to raise funds, and, if we are able to find buyers of such securities, those future securities may have rights, preferences or privileges senior to those of the rights of our common stock. In connection with a sale of stock, our stockholders would experience dilution. In addition, in the current economic climate, we cannot be certain that additional financing will be available to us on favorable terms when required, or at all.

WE ARE HIGHLY DEPENDENT UPON THE LIFE SCIENCES INDUSTRY, AND FACTORS THAT ADVERSELY AFFECT THAT MARKET, INCLUDING CONSOLIDATION, COULD ALSO ADVERSELY AFFECT US

Most of our revenue to date has come from pharmaceutical companies and a limited number of other clients in the life sciences industry, and our future growth depends, in large part, upon sales to the life sciences market. As a result, demand for our solutions could be affected by any factors that could adversely affect the demand for healthcare products, which are purchased and sold pursuant to contracts managed through our solutions. The financial condition of our clients and their willingness to pay for our solutions are affected by factors that may impact the purchase and sale of healthcare products, including competitive pressures, changes in regulations, decreasing operating margins within the industry, currency fluctuations, active geographic expansion and government regulation. The life sciences market has been adversely affected by the recent economic downturn and is undergoing intense consolidation. We cannot assure you that we will not experience declines in revenue caused by mergers or consolidations among our clients and potential clients.

WE HAVE MANY COMPETITORS AND POTENTIAL COMPETITORS AND WE MAY NOT BE ABLE TO COMPETE EFFECTIVELY

The market for our products and services is competitive and subject to rapid change. We encounter significant competition for the sale of our contract management software from the internal information systems departments of existing and potential clients, software companies that target the contract management markets and professional services organizations. Our competitors vary in size and in the scope and breadth of products and services offered. We experience competition for market share and pressure to reduce prices and make sales concessions, which could materially and adversely affect our revenues and margins. We cannot assure you that our current or future competitors will not develop products or services that may be superior in one or more respects to ours or that may gain greater market acceptance. Some of our competitors have established or may establish cooperative arrangements or strategic alliances among themselves or with third parties, thus enhancing their abilities to compete with us. It is likely that new competitors will emerge and rapidly acquire market share. We cannot assure you that we will be able to compete successfully against current or future competitors or that the competitive pressures faced by us will not materially and adversely affect our business, operating results and financial condition.

WE MAY NOT BE SUCCESSFUL IN DEVELOPING OR ACQUIRING NEW TECHNOLOGIES OR BUSINESSES AND THIS COULD HINDER OUR EXPANSION EFFORTS

We may consider additional acquisitions of or new investments in complementary businesses, products, services or technologies. We cannot assure you that we will be successful in our product development efforts or that we will be able to identify appropriate acquisition or investment candidates. Even if we do identify suitable candidates, we cannot assure you that we will be able to make such acquisitions or investments on terms acceptable to us. Furthermore, we may issue debt or issue equity securities to pay for any future acquisitions. The issuance of equity securities could be dilutive to our existing stockholders and the issuance of debt could limit our available cash and accordingly restrict our activities.

WE MADE TWO ACQUISITIONS IN 2008 AND MAY HAVE DIFFICULTY INTEGRATING THEM. WE MAY MAKE ADDITIONAL ACQUISITIONS

Since the beginning of 2008, we have acquired the ClaimRight business and Edge Dynamics, Inc. We may make additional acquisitions. Any other company that we acquire may be distant from our headquarters in Edison, New Jersey and have a culture different from ours as well as technologies, products and services that our employees will need to understand and integrate with our own. We will have to assimilate the acquired employees, technologies and products, and that effort is difficult, time-consuming and may be unsuccessful. If we are not successful, our investment in the acquired entity may be lost, and even if we are successful, the process of integrating an acquired entity may divert our attention from our core business.

WE HAVE MULTIPLE FACILITIES AND WE MAY EXPERIENCE DIFFICULTIES IN OPERATING FROM THESE DIFFERENT LOCATIONS

We operate out of our corporate headquarters in Edison, New Jersey, engineering offices in Redwood City, California, Portland, Maine and Gandhinagar, India, and an office facility in London, England. The geographic distances between our offices makes it more challenging for our management and other employees to collaborate and communicate with each other than if they were all located in a single facility, and, as a result, increases the demand on our managerial, operational and financial resources. Also, a significant number of our sales and professional services employees work remotely out of home offices, which adds to this demand.

We depend on the services of our senior management and key technical personnel. The loss of the services of key employees, and the inability to attract new employees to fill crucial roles, could have a material adverse effect on our business, financial condition and results of operations.

OUR EFFORTS TO PROTECT OUR INTELLECTUAL PROPERTY MAY NOT BE FULLY EFFECTIVE, AND WE MAY INADVERTENTLY INFRINGE ON THE INTELLECTUAL PROPERTY OF OTHERS

Despite our efforts to protect our proprietary rights, unauthorized parties may attempt to copy aspects of our products or to obtain the use of information that we regard as proprietary. In addition, the laws of some foreign countries do not protect our proprietary rights to as great an extent as do the laws of the United States. We cannot assure investors that our means of protecting our proprietary rights will be adequate or that our competitors will not independently develop similar technology.

We are not aware that any of our products infringe the proprietary rights of third parties. We cannot assure investors, however, that third parties will not claim infringement by us with respect to current or future products. We expect that software product developers will increasingly be subject to infringement claims as the number of products and competitors in our industry segment grows and the functionality of products in different industry segments overlaps. Any such claims, with or without merit, could be time-consuming, result in costly litigation, cause product shipment delays or require us to enter into royalty or licensing agreements. Such royalty or licensing agreements, if required, may not be available on terms acceptable to us or at all, which could have a material adverse effect upon our business, operating results and financial condition.

We lease approximately 15,400 square feet of office space in Edison, New Jersey under a lease expiring in 2009, for use by executive, professional services and administrative personnel in both our business segments. A portion of our development, customer support and administrative offices for both market segments are located in approximately 10,700 square feet of leased office space located in Portland, Maine under a lease expiring December 31, 2011. Also, we lease approximately 13,835 square feet of office space in Redwood City, California under a lease expiring in 2011, for use by development, sales and marketing personnel in primarily our other industries market segment. In addition, we lease or sublease approximately 20,500 square feet of office space in Chicago, Illinois under a lease expiring in 2011, all of which is subleased under terms expiring in 2011; 3,900 square feet of office space in London, England under a lease expiring in 2011, of which approximately one-half is subleased under terms expiring in 2011; and 1,300 square feet of office space in Gandhinagar, India, under a lease expiring in 2012.

We are involved, from time to time, in contractual disputes, litigation and potential claims arising in the ordinary course of business. We do not believe that the resolution of these matters will have a material adverse effect on our financial position or results of operations. We are not a party to any material pending legal proceedings.

The following sets forth the names and certain biographical information regarding the officers and significant employees of the Company.

JOHN A. RADE, age 74, has served as a director since July 2005, as Chairman of the Board since August 8, 2005, and as our President and Chief Executive Officer since August 15, 2006. Mr. Rade was the President and CEO of AXS-One, Inc., formerly Computron Software, Inc., a publicly-traded software company, from 1997

until his retirement in 2004. Before joining Computron, he managed the pharmaceutical industry practice for American Management Systems, Inc., a management consulting and information technology company. He was a founder of S-Cubed, Inc., a developer and marketer of advanced software development tools. Mr. Rade’s career in software and information technology includes international management postings, spans several decades and includes leadership roles in other software development companies, management consulting and industrial automation. Mr. Rade holds a BS in Physics from John Carroll University.

KEVIN M. HARRIS, age 46, has served as I-many’s Chief Financial Officer since June 2003. From January 2001 to April 2003, Mr. Harris served as division controller for Hewlett Packard’s middleware division. From March 2000 to January 2001, Mr. Harris served as the corporate controller for Bluestone Software. From October 1998 to December 1999, Mr. Harris worked for Marketing Specialists, a food sales and marketing organization, as executive vice president of their mid-Atlantic division. From November 1996 to October 1998, Mr. Harris worked for Rogers-American Company, a food sales and marketing organization, as vice president/general manager of their Philadelphia office. Mr. Harris holds B.S. and M.B.A. degrees from Drexel University.

LAWRENCE LINDSEY, age 42, has served as I-many’s Executive Vice President of Product Operations since he joined the Company in April 2008. From September 2006 to April 2008, Mr. Lindsey served as vice president of engineering at Symantec Corporation for online platform and partner services. From September 2004 to September 2006, Mr. Lindsey was vice president of engineering for Nsite Software (now a unit of NASDAQ-traded Business Objects S.A.), with responsibility for all product strategy, development, and production operations. From September 1997 to August 2004, he held various senior management positions at Oracle Corporation, including senior director of development for the Healthcare Industry Group. Mr. Lindsey holds a Bachelor of Science in Computer Science from the University of Southern California.

ROBERT G. SCHWARTZ, JR., age 44, has served as I-many’s Vice President, General Counsel and Secretary since September 2001. Prior to joining I-many, Mr. Schwartz has served as vice president, general counsel, secretary and a director of Emptoris, Inc., a developer of strategic sourcing software; assistant general counsel of Cambridge Technology Partners, a publicly-held software integration services provider; vice president, general counsel and secretary of Astea International Inc., a publicly-held developer of customer relationship management software; and as an associate at Goodwin Procter LLP, a national law firm. Mr. Schwartz holds a B.A. from Amherst College and a J.D. from Harvard Law School.

A. TODD SHYTLE, age 48, has served as our Senior Vice President of Sales since March 2008 and as Vice President of Sales since July 2004. He has been with the Company since 1999 and has served in sales management roles since January 2004, including as Vice President of Sales for Life Sciences. Prior to joining I-many, Mr. Shytle was responsible for sales and market development in the life sciences industry for Manugistics, Inc., a provider of software and services for supply chain management. He has also served in various sales roles at Johnson & Johnson, United States Surgical Corporation, and Eastman Kodak. Mr. Shytle holds an M.B.A. from the School of Business at Queens College in Charlotte, North Carolina.

MELISSA WALKER, age 41, has served as Vice President of Professional Services since July 2008. She is responsible for the Company’s professional services, hosting services, product deployment, and training and education for the entire I-many family of products. She has been with the Company since 2000, previously serving as Senior Director of Professional Services. Previously, Ms. Walker served as a senior manager at Belcan Engineering for implementation services of accounting, manufacturing and distribution applications. Prior to Belcan, Ms. Walker was an accounting manager for MedPlus Inc., a publicly held software company that specializes in barcode technologies and electronic patient record systems. Ms. Walker holds a Bachelor of Science in Business Management from the University of Cincinnati.

MICHAEL T. ZUCKERMAN, age 52, has served as I-many’s Senior Vice President of Marketing since February 2008. From March 2006 through December 2006, Mr. Zuckerman served as Senior Vice President & General Manager of Immersion Corporation’s 3D Business Unit. From October 2004 through March 2006,

Mr. Zuckerman served as the Senior Vice President & General Manager of Immersion Corporation’s Industrial Business Unit. From October 2003 through October 2004, Mr. Zuckerman served as Immersion Corporation’s Senior Vice President, Marketing. From June 2000 through June 2003, Mr. Zuckerman served as Vice President of Marketing for Verity, Inc. From July 2003 through September 2003, he served as Verity’s Vice President of Sales for America’s West. Prior to joining Verity, Inc. Mr. Zuckerman served as Vice President of Sales and Marketing at Sensar, Inc., a provider of network security products. Mr. Zuckerman holds a B.S. in Electrical Engineering from the University of Maryland.

Our common stock trades on the NASDAQ Capital Market under the symbol “IMNY.” The following table sets forth the high and low closing sales prices per share for our common stock as reported on the NASDAQ Global Market and/or the NASDAQ Capital Market for each full quarterly period within the two most recent fiscal years. As of March 3, 2009, there were 280 holders of record of our common stock.

We have never paid dividends and do not anticipate paying dividends in the foreseeable future. For information regarding securities authorized for issuance under the Company’s equity compensation plans, see Item 12.

On November 24, 2008, we received notice that our common stock would be delisted from the NASDAQ Capital Market subject to our right to a hearing before a NASDAQ Listing Qualifications Panel. We requested a hearing and, on January 8, 2009, presented our plan to the Panel for regaining compliance with all applicable requirements for continued listing. On March 20, 2009, the Company received notification from the Panel that it had determined to grant the Company’s request to remain listed on the NASDAQ Capital Market, subject to the condition that, among other things, the Company evidence stockholders’ equity at or above $2.5 million on or before May 26, 2009. The Company is required to provide the Panel with prompt notification of any significant events concerning its ability to regain compliance with NASDAQ’s listing standards, and the Panel reserves the right to reconsider the terms of this exception under circumstances that make continued listing of the Company’s common stock on the NASDAQ Capital Market unwarranted. While the Company is working to regain compliance, there can be no assurance that the Company will be able to regain compliance by the deadline established by the Panel. If our common stock is not listed on any of the NASDAQ Stock Market, the New York Stock Exchange or the NYSE Alternext US Market (formerly the American Stock Exchange) for more than five days, we would be in default on our senior notes sold by the Company on December 31, 2007 in the principal amount of $17 million. The Company has initiated discussions to seek a waiver of this default from the holders of the notes; however, there can be no assurance that it will be able to obtain a waiver on favorable terms, if at all. If the Company is unable to obtain a waiver, it would be in default under the notes and would be unable to repay the notes without raising additional capital and its ability to continue as a going concern would be in significant doubt.

The graph below compares the cumulative total return on I-many’s common stock with the NASDAQ Composite Market Index (U.S. companies) and Morgan Stanley High Tech Index for the period from January 1, 2004 to December 31, 2008. The comparison assumes that $100 was invested on January 1, 2004 in I-many’s common stock and in each of the comparison indexes, and assumes reinvestment of dividends, where applicable. Stock price performance, presented for the period from January 1, 2004 through December 31, 2008, is not necessarily indicative of future results. This stock price performance information is “furnished” and not “filed” and shall not be deemed “soliciting material” or subject to Regulation 14A, shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by reference in any filing under the Exchange Act or the Securities Act of 1933, as amended.

The selected condensed consolidated financial data presented below as of and for each of the years in the five-year period ended December 31, 2008 are derived from our financial statements. Historical results are not necessarily indicative of future results. The following selected financial data should be read in conjunction with “Management’s Discussion and Analysis of Financial Condition and Results of Operations” and our financial statements and notes to those statements and other financial information included elsewhere in this report.

The following discussion of our financial condition and results of operations should be read in conjunction with our financial statements and related notes. In addition to historical information, the following discussion and other parts of this report contain forward-looking statements that involve risks and uncertainties. Our actual results may differ materially from those anticipated by such forward-looking statements due to various factors, including, but not limited to, those set forth under “Risk Factors” and elsewhere in this report. Management does not believe that inflation or changing prices has had a material effect on our revenues and income from continuing operations.

We provide software and related services that allow our clients to more effectively manage their contract-based, business-to-business relationships through the entirety of the contract management lifecycle. We operate our business in two segments: health and life sciences and industry solutions. The health and life sciences line of business markets and sells our products and services to companies in the life sciences industries, including pharmaceutical and medical product companies, wholesale distributors and managed care organizations. The industry solutions line of business targets all other industries.

Our primary products and services were originally developed to manage complex contract purchasing relationships in the healthcare industry. Our software is currently licensed by 19 of the 20 largest world-wide pharmaceutical manufacturers, ranked according to 2007 annual pharmaceutical company revenues. As the depth and breadth of our product suites have expanded, we have added companies in the industry solutions markets to our customer base.

We have generated revenues from both products and services. Recurring revenue, which consists of maintenance, support and hosting fees directly related to our licensed software products, and product subscription revenues, accounted for 59.7% of net revenues in 2008 versus 48.6% of net revenues in 2007. Services revenue, which is comprised of professional service fees and reimbursable out-of-pocket expenses derived from consulting, installation, business analysis and training services related to our software, accounted for 30.7% of net revenues in 2008 versus 33.3% of net revenues in 2007. License revenue, which consists of non-recurring license fees generated from perpetual license agreements, accounted for 9.6% of net revenues in 2008 versus 18.1% of net revenues in 2007.

On November 6, 2006, we completed a private placement of our securities, issuing 3,535,566 shares of our common stock and common stock purchase warrants to purchase up to an additional 1,060,663 shares of common stock. The per unit price of the private placement offering was $1.98, with each unit comprised of one share of common stock and a warrant to purchase three-tenths of a share of common stock. The warrants are exercisable at $2.11 per share until November 2011. Net proceeds to the Company were approximately $6.5 million, after deducting commissions and other fees.

On December 31, 2007, we completed a private placement of $17.0 million of senior convertible notes, which bear interest at 6.5% per annum, payable quarterly in arrears, and will mature on December 31, 2012. The notes are convertible into shares of the Company’s common stock at a conversion price of $3.8192 per share, subject to adjustment in the event of a merger or other change in control of the Company. Also, the notes can be redeemed at par by the investors on December 31, 2010, or redeemed at par by us at any time beginning on December 31, 2010. Net proceeds to the Company from the sale of the notes were approximately $15.8 million, after deducting commissions and other fees. We will be in default under these notes in the event that our common stock is delisted from the NASDAQ Capital Market and we are unable to obtain a waiver from the holders of the notes. See “Risk Factors” in Item 1A and note 4 to the consolidated financial statements in Item 8.

On February 20, 2008, we completed our purchase of the assets related to the ClaimRight data validation software business from Global Healthcare Exchange LLC and Global HealthCare Exchange, Inc. for $2.0 million, which consisted of $1.4 million in cash paid upon closing, assumed liabilities of $206,000, transaction costs of $181,000, and an additional $200,000 in cash consideration that was paid in January 2009 based on the realization of certain defined performance milestones. The ClaimRight business was located in Ambler, Pennsylvania and marketed software to pharmaceutical providers for the processing and validating of pharmaceutical claim submissions. This purchase provided us with an established customer base and technology that we believe will enhance our product offering to our pharmaceutical manufacturing clients.

On May 5, 2008, we completed our acquisition of all of the outstanding capital stock of Edge Dynamics, Inc., a privately-held developer of channel- and demand-management software based in Redwood City, California, for a purchase price of $500,000 plus the repayment and assumption of other obligations. The total merger consideration of approximately $5.1 million consisted of $500,000 in cash paid to the shareholders of Edge Dynamics, $1.7 million in cash paid to extinguish Edge Dynamics’ outstanding bank debt, the assumption of Edge Dynamics’ liabilities of approximately $2.9 million, and transaction costs of approximately $290,000, less Edge Dynamics’ cash balance of $231,000. The Edge Dynamics acquisition provided products and technology that we believe will enhance our product offerings to our customers in the health and life sciences segment.

We implemented a number of employee headcount reductions and office downsizings during the period June 2001 through March 2004, after which our aggregate quarterly spending on cost of products and services, sales and marketing, research and development and general and administrative expenses (excluding acquisition-related charges and noncash stock compensation) remained fairly steady—ranging from $9.2 million to $10.4 million—through the first quarter of 2006. In early 2006, we began to increase our spending, primarily on research and development and professional services, in order to (i) accelerate development of future releases of our product offerings in the health and life sciences segment, (ii) work on resolving defects in one of our

software products, as explained in further detail in “Critical Accounting Policies—Revenue Recognition” in this Item 7, and (iii) augment staff levels at a number of professional services engagements, primarily in connection with implementations of the software product with performance defects at customer sites. This spending reached its peak at $12.5 million during the three-month period ended June 30, 2007, subsequently falling to $11.4 million during the three-month period ended December 31, 2007. Meanwhile, our revenues had been increasing for six consecutive quarters through the three-month period ended December 31, 2007, resulting in our lowest quarterly operating loss that quarter since the three-month period ended September 30, 2004 and our second lowest quarterly operating loss since our initial public offering in July 2000.

In 2008, our sales were significantly lower than expected and relative to 2007 levels. We believe that general economic conditions affecting the health and life science industries, weak sales force execution, a relatively small and recent base of customers using our next generation products and competitive pressures were the primary causes behind this decrease. Meanwhile, our expenses had increased during the first six months of 2008, largely as a direct result of our acquisitions of the ClaimRight business and Edge Dynamics. In response to this deterioration in our sales results and our increased operating losses, we reduced our headcount by a total of 28 employees during the three-month period ended June 30, 2008, incurring $346,000 in estimated severance costs, and cut back on projected future hiring plans. In December 2008, we implemented a significant restructuring of our operations in order to streamline operations and better align operating expenses levels with a conservative revenue forecast for 2009. As part of this downsizing, we eliminated 49 employee positions, moved our London office to a smaller facility, and incurred $857,000 in severances and lease loss costs. Our total employee headcount has decreased from 199 at December 31, 2007 to 167 at December 31, 2008.

We generate revenues from licensing our software and providing professional services, training and maintenance and support services. Software license revenues are attributable to the addition of new customers and the expansion or renewal of existing customer relationships through licenses covering additional users, licenses of additional software products and license renewals.

We recognize software license fees upon execution of a signed license agreement and delivery of the software to customers, provided there are no significant post-delivery obligations, the payment is fixed or determinable and collection is probable. In multiple-element arrangements, we allocate a portion of the total fee to professional services, training and maintenance and support services based on the fair value of those elements, which is defined as the price charged when those elements are sold separately. The residual amount is then allocated to the software license fee. In cases where we agree to deliver unspecified additional products in the future, the license fee is recognized ratably over the term of the arrangement beginning with the delivery of the first product. In cases where we agree to deliver specified additional products or upgrades in the future, recognition of the entire license fee, including any related maintenance and support fees, is deferred until after the specified additional products or upgrades are delivered and made generally available to all customers. If an acceptance period is required, revenues are deferred until customer acceptance. In cases where collection is not deemed probable, we recognize the license fee as payments are received. In cases where significant production or customization is required prior to attaining technological feasibility of the software, license fees are recognized on a percentage-of-completion basis and are credited to research and development expenses as a funded development arrangement. After the software attains technological feasibility, recognizable license fees are reported as license revenue.

In 2007, we began to classify our reported net revenues into three revenue categories—Recurring, Services and License revenues—after having previously reported our revenues as being either Product or Service. Recurring revenue consists of (i) fees generated from the provision of maintenance, support, and hosting services and (ii) subscription revenues. Services revenue is now comprised of professional service and training fees and reimbursable out-of-pocket expenses. License revenue consists of non-recurring license fees generated from perpetual license agreements.

We offer current and prospective customers the option to enter into a subscription agreement as an alternative to our standard perpetual license contract model. We believe our subscription offering has expanded the market to customers that find regular subscription payments an easier and more flexible licensing of our software, and subscription arrangements have the potential to provide us with smoother and more predictable revenue growth. The standard subscription arrangement is presently a fixed fee agreement over three to five years, covering license fees, unspecified new product releases and maintenance and support, generally payable in equal quarterly or annual installments commencing upon execution of the agreement. Prior to 2006, more than half of the executed subscription arrangements included a provision allowing the agreement to convert free-of-charge to a perpetual license after the completion of the initial term plus any extensions, generally after five years, after which time the customer would have the option of paying for the continuation of maintenance and support. Beginning in 2006, we have generally discontinued including free-of-charge perpetual conversion provisions in new subscription arrangements. Also included in subscription revenues are license fees generated from perpetual license arrangements with rights to unspecified additional products, which are treated as subscription arrangements for accounting purposes. For subscription arrangements which include rights to specified products which are not yet generally available to customers, revenue recognition is deferred until all elements of the arrangement including any such specified products have been delivered. For all other subscription arrangements, we recognize all revenue ratably over the term of the subscription agreement commencing upon delivery of the initial product. Subscription installment amounts that are not yet contractually billable to customers are not reflected in deferred revenues on our consolidated balance sheet.

Maintenance and customer support fees are recognized ratably over the term of the maintenance contract, which is generally twelve months. When maintenance and support is included in the total license fee, we allocate a portion of the total fee to maintenance and support based upon the price paid by the customer when sold separately, generally as renewals in the second year.

Professional service revenues are recognized as the services are performed. If conditions for acceptance exist, professional service revenues are recognized upon customer acceptance. For fixed fee professional service contracts, we provide for anticipated losses in the period in which the loss is probable and can be reasonably estimated. Training revenues are recognized as the services are provided. Included in training revenues are registration fees received from participants in our annual off-site user training conferences.

Payments received from customers at the inception of a maintenance period are treated as deferred service revenues and recognized ratably over the maintenance period. Payments received from customers in advance of product shipment or revenue recognition are treated as deferred product revenues and recognized when the product is shipped to the customer or when otherwise earned.

Subscription arrangements, including a small number of perpetual license arrangements with rights to unspecified additional products that are treated as subscriptions for accounting purposes, represent a significant proportion of our new licenses. In 2007, 18 of the 35 license contracts (minimum value of $50,000) that were sold were treated as subscription arrangements for accounting purposes. In 2008, six of the 14 license deals (minimum value of $50,000) that were sold are likewise being accounted for as subscriptions. During 2007 and 2008, we recognized $5.4 million and $5.3 million, respectively, in recurring revenue related to such agreements.

During the third quarter of 2005, we became aware of certain defects in the then-current version of one of our software products, which was first shipped to customers in the fourth quarter of 2004. These defects, which were not identified in pre-release product testing, affected the performance of the software for a portion of our customers depending on each customer’s particular implementation environment and its intended use of the software. Because certain concessions had been made to customers in connection with these defects, we have generally not recognized revenue from sales of this software product and related implementation services since the beginning of the third quarter of 2005, except in those cases in which it was determined that the customer was not likely to be affected by the known, unresolved software defects. During 2006, new versions of the software were released, but we continued to experience problems with implementations at several customer sites. In 2007,

we released new versions of the software which were designed to resolve known performance defects with minimal additional functionality. During the quarters ended June 30 and September 30, 2007, we successfully completed implementations of the newest version of this software at multiple customer sites and made progress with other customer implementations, and accordingly have begun recognizing revenue from this software on a limited basis. However, we are continuing to defer all recurring, services and license revenue in connection with (i) implementations of this software program that are not yet complete, and (ii) any customers for which a concession is probable and an agreement formalizing a concession amount has not been executed. As of December 31, 2007 and 2008, we have reversed and deferred $671,000 and $875,000, respectively, of otherwise-recognizable revenue, based principally on our determination that license fees were not fixed and determinable because of the possibility of future concessions.

On January 1, 2006, we adopted Statement of Financial Accounting Standards (“FAS”) No. 123 (revised 2004) (“FAS 123(R)”), “Share-based Payment.” Under FAS 123(R), we measure and record the compensation cost of employee and director services received in exchange for stock option grants and other equity awards based on the grant-date fair value of the awards. The values of the portions of the awards that are ultimately expected to vest are recognized as expense over the requisite service periods. We account for stock options and awards granted to non-employees other than directors using the fair-value method.

Under the fair-value method, compensation associated with equity awards is determined based on the estimated fair value of the award itself, measured using either current market data or an established option pricing model. The measurement date for employee and director awards is generally the date of grant. The measurement date for awards granted to non-employees other than directors is generally the date that performance of certain services is complete.

Our calculations of the fair value of stock option grants were made using the Black-Scholes option pricing model with the following assumptions, and resulted in the following weighted average grant-date fair values of options granted during the years ended December 31:

The risk-free interest rate is derived quarterly from the published US Treasury yield curve, based on expected term, in effect as of the last several days of the quarter. We use historical volatility of the Company’s common stock to estimate expected volatility. For the years ended December 31, 2006 and 2007, the expected term of options granted was estimated to be equal to the average of the contractual life of the options and the grant’s average vesting period. For the year ended December 31, 2008, the expected term of options was derived from Company historical data, including, among other things, option exercises, forfeitures and cancellations.

We record provisions for doubtful accounts based on a detailed assessment of our accounts receivable and related credit risks. In estimating the allowance for doubtful accounts, management considers the age of the accounts receivables, our historical write-off experience, the credit worthiness of customers and the economic conditions of the customers’ industries and general economic conditions, among other factors. Should any of these factors change, the estimates made by management will also change, which could affect the level of our

future provision for doubtful accounts. If the assumptions we used to calculate these estimates do not properly reflect future collections, there could be an impact on future reported results of operations. The provisions for doubtful accounts are included in general and administrative expenses in the consolidated statements of operations.

Acquired intangible assets (excluding goodwill) are amortized on a straight-line basis over their estimated useful lives and reviewed for impairment on an annual basis, or on an interim basis if an event or circumstance occurs between annual tests indicating that the assets might be impaired. The impairment test will consist of comparing the cash flows expected to be generated by the acquired intangible asset to its carrying amount. If the asset is considered to be impaired, an impairment loss will be recognized in an amount by which the carrying amount of the asset exceeds its fair value.

Goodwill is tested for impairment at the reportable segment level, which is the same as the reporting unit level, using a two-step approach. The first step is to compare the fair value of a reporting unit to its carrying amount, including goodwill. If the fair value of the reporting unit is greater than its carrying amount, goodwill is not considered impaired and the second step is not required. If the fair value of the reporting unit is less than its carrying amount, the second step of the impairment test measures the amount of the impairment loss, if any, by comparing the implied fair value of goodwill to its carrying amount. If the carrying amount of goodwill exceeds its implied fair value, an impairment loss is recognized equal to that excess. The implied fair value of goodwill is calculated in the same manner that goodwill is calculated in a business combination, whereby the fair value of the reporting unit is allocated to all of the assets and liabilities of that unit (including any unrecognized intangible assets), with the excess “purchase price” over the amounts assigned to assets and liabilities representing the implied fair value of goodwill. Goodwill is tested for impairment at least annually, or on an interim basis if an event occurs or circumstances change that would likely reduce the fair value of a reporting unit below its carrying value. If the assumptions we used to estimate fair value of goodwill change, there could be an impact on future reported results of operations.

A deferred tax asset or liability is recorded for temporary differences in the bases of assets and liabilities for book and tax purposes and loss carry forwards based on enacted tax rates expected to be in effect when these temporary items are expected to reverse. Valuation allowances are provided to the extent it is more likely than not that all or a portion of the deferred tax assets will not be realized.

Our agreements with customers generally include certain provisions obligating us to indemnify the customer against losses, expenses, and liabilities from damages that may be awarded against the customer in the event that our products are found to infringe upon a patent, copyright, trademark, or other proprietary right of a third party. The agreements generally seek to limit the scope of remedies for such indemnification obligations in a variety of industry-standard respects, including our right to replace an infringing product. To date, we have not had to reimburse any of our customers for any losses related to these indemnification provisions and no claims were outstanding as of December 31, 2008. We do not expect that any significant impact on financial position or the results of operations will result from these indemnification provisions.

Research and development costs are charged to operations as incurred. Based on our product development process, technological feasibility is established upon completion of a working model. Costs incurred by the

Company between completion of the working model and the point at which the product is ready for general release have not been material. As such, all software development costs incurred to date have been expensed as incurred.

We incurred research and development expenses of $15.2 million for the year ended December 31, 2008, which included amounts assigned to acquired in-process technology for the quarters ended March 31, 2008 and June 30, 2008 of $760,000 and $800,000, respectively. The values assigned to acquired in-process technology were determined by identifying those acquired specific in-process research and development projects that would be continued and for which (a) technological feasibility had not been established at the acquisition date, (b) there was no alternative future use, and (c) the fair value was estimable with reasonable reliability.

Net revenues decreased by $6.2 million, or 15.2%, to $34.4 million for the year ended December 31, 2008 from $40.6 million for the year ended December 31, 2007. Recurring revenue increased by $819,000, or 4.2%, to $20.5 million for the year ended December 31, 2008 from $19.7 million in the same period a year earlier, primarily attributable to an increase of $1.3 million, or 13.6%, in maintenance and support revenues in our health and life sciences segment, which resulted largely from our acquisitions of Edge Dynamics and the ClaimRight business, partially offset by a decrease of $420,000, or 11.0%, in maintenance and support revenues in our industry solutions segment. Service revenue decreased by $2.9 million, or 21.7%, to $10.6 million in the year ended December 31, 2008 versus $13.5 million in 2007, which included $1.8 million in previously-deferred service revenues for work performed in prior reporting periods. The 2007 catch-up deferral recognition notwithstanding, service revenues were lower relative to 2007 in both our health and life sciences and industry solutions segments due primarily to lower utilization attributable to a significant decreases in license bookings in both segments. License revenues decreased by $4.1 million, or 55.2%, to $3.3 million for the year ended December 31, 2008 from $7.3 million in 2007.

As indicated in the table below, the gross value of license contracts sold during 2008 decreased by 74.0% versus 2007, due primarily to a decrease in the number of license transactions (minimum value of $50,000) from 35 to 14. We believe that general economic conditions affecting the health and life science industries, weak sales execution, a relatively small and recent base of customers using our next generation products and competitive pressures were the primary causes behind this decrease. See Risk Factors in Part I, Item 1A of this filing.

We believe that a significant proportion of future license contracts could be subscription arrangements or could have conditions which mandate deferred revenue recognition. As a result, in future reporting periods we expect recognized revenues to exclude portions of the license revenue generated from contracts entered into in those periods but also to include larger proportions of revenues from contracts entered into in prior reporting periods.

Reconciliation of Value of License Transactions to Reportable License Revenue

The above financial information is provided as additional information and is not in accordance with or an alternative to generally accepted accounting principles, or GAAP. We believe its inclusion can enhance an overall understanding of our past operational performance and also our prospects for the future. This reconciliation of license revenues is made with the intent of providing a more complete understanding of our sales performance, as opposed to GAAP revenue results, which do not include the impact of newly-executed subscription agreements and other deferred license arrangements that are material to the ongoing performance of our business. This information quantifies the various components comprising current license revenue, which in each period consists of the total value of licenses sold in current periods, plus license revenue recorded in the current period from contracts sold in prior periods, less the value of license contracts sold in the current period that is not yet recognizable. Included in the gross value of license contracts sold amounts are license and non-cancelable subscription fee obligations that are not currently recognizable as product revenue upon execution of the license agreement because all the requirements for revenue recognition (see “Critical Accounting Policies—Revenue Recognition” in this Item 7) are not present, such as the presence of extended payment terms, future software deliverables, or customer acceptance provisions, for example. The gross value of license contracts sold also includes amounts that are not yet contractually billable to customers, and any such unbilled amounts are not reflected in deferred revenues on our consolidated balance sheet. Management uses this information as a basis for planning and forecasting core business activity in future periods and believes it is useful in understanding our results of operations. Also, payouts under our sales compensation and executive bonus plans are based in large part on the gross values of license contracts sold in each period. The presentation of this additional revenue information is not meant to be considered in isolation or as a substitute for revenues reported in accordance with GAAP in the United States. There can be no assurance that the full value of licenses sold and deferred to future reporting periods will ultimately be recognized as total net revenues.

Total net revenues derived from our health and life sciences segment decreased by $2.3 million, or 7.3%, to $29.1 million for the year ended December 31, 2008 from $31.4 million in the prior year. This decrease was

primarily attributable to reductions of $2.9 million, or 48.8%, in license revenue, and $1.1 million, or 10.6%, in service revenue, partially offset by increases of $1.3 million, or 13.6%, in maintenance and support revenue and $529,000, or 157.4%, in hosting revenue. As indicated in the above table, the gross values of license contracts sold in this segment during the year ended December 31, 2008 decreased by $11.5 million, or 26.0%, versus 2007 due primarily to a significant decrease in the number of license transactions, and this decrease in license bookings had a depressing effect on service revenues in 2008 versus 2007. The growth in maintenance and support and hosting revenues was mostly attributable to the in-force customer relationships we assumed in the Edge Dynamics and ClaimRight acquisitions.

Total net revenues derived from the industry solutions segment decreased by $3.9 million, or 42.0%, to $5.3 million for the year ended December 31, 2008 from $9.2 million in 2007. All revenue sources experienced declines: service revenue decreased by $1.8 million, or 65.8%; license revenue decreased by $1.1 million, or 84.4%; and recurring revenue decreased by $1.0 million, or 18.9%. Revenue in this segment has been trending lower over the past several quarters due to decreasing licensing activity, which had largely been a result of recent product defect issues in one of our key software products previously marketed primarily to the industry solutions segment (see “Critical Accounting Policies – Revenue Recognition” in this Item 7 above) and is now largely attributable to, in addition to the factors described above for our sales in general, reduced sales and marketing expenditures for products targeted to this segment.

COST OF RECURRING REVENUE. Cost of recurring revenue consists primarily of payroll and related costs for providing maintenance and support services, and, to a lesser extent, hosting services. Cost of recurring revenue for the year ended December 31, 2008 was essentially unchanged at $6.4 million versus the year ended December 31, 2007. An increase of $538,000 in salary and related costs, resulting principally from merit increases and severances paid during the second quarter of 2008, was entirely offset by decreases of (i) $257,000 in hosting costs incurred by our subsidiary based in the United Kingdom resulting from the cancellation of a large customer’s hosting arrangement, (ii) $122,000 in consulting costs and (iii) sundry other expense reductions. As a percentage of recurring revenue, cost of recurring revenue decreased to 31.1% for the year ended December 31, 2008 from 32.2% for the year ended December 31, 2007, with this decrease being entirely attributable to higher recurring revenue in 2008.

COST OF SERVICES REVENUE. Cost of services revenue consists primarily of payroll and related costs and subcontractor fees for providing implementation, consulting and training services. Cost of services revenue decreased by $1.1 million, or 10.4%, to $9.9 million in the year ended December 31, 2008 from $11.0 million in the year ended December 31, 2007. This decrease is primarily attributable to reductions of $819,000 in the cost of consultants and $208,000 in travel expenses, both of which are primarily attributable to reduced customer demand for professional services, particularly in our industry solutions segment, as discussed above in this Item 7. As a percentage of service revenues, cost of services revenue increased to 93.6% for the year ended December 31, 2008 from 81.8% for the year ended December 31, 2007.

COST OF THIRD PARTY TECHNOLOGY. Cost of third party technology, which consists of amounts due to third parties for royalties related to integrated technology, has not been significant historically. Cost of third party technology decreased by $119,000, or 39.6%, to $181,000 for the year ended December 31, 2008 from $300,000 in the year ended December 31, 2007. Much of the expense in 2007 was comprised of accelerated amortization of prepaid royalty amounts in advance of the expiration date of the related technology agreements, while little such amortization was recorded in 2008.

AMORTIZATION OF OTHER ACQUIRED INTANGIBLE ASSETS. Amortization of acquired intangible assets related to our acquisitions amounted to $471,000 in the year ended December 31, 2008, which represents a $286,000, or 154.7%, increase in amortization from the prior year. This increase is attributable to amortization of the newly-acquired intangible assets in connection with the acquisitions of the ClaimRight business and Edge Dynamics.

SALES AND MARKETING. Sales and marketing expenses consist primarily of payroll and related benefits for sales and marketing personnel, commissions for sales personnel, travel costs, recruiting fees, expenses for trade shows and advertising and public relations expenses. Sales and marketing expense decreased by $1.2 million, or 11.5%, to $8.9 million in the year ended December 31, 2008 from $10.1 million in the year ended December 31, 2007. This decrease was primarily attributable to a $1.5 million reduction in sales commission costs that was a direct result of the decrease in the gross value of license contracts sold as discussed above in this Item 7, partially offset by an increase of $420,000 in sales and marketing non-commission salary and related costs due to slightly higher staffing levels, merit increases, and one-time severance costs incurred in the 2^nd quarter of 2008. As a percentage of total net revenues, sales and marketing expense increased to 25.9% in 2008 versus 24.9% in 2007. Management expects sales and marketing costs to be lower in 2009 versus 2008, both in absolute terms and as a percentage of revenue, as a result of our elimination of 13 of 28 sales and marketing positions in December 2008.

RESEARCH AND DEVELOPMENT. Research and development expenses consist primarily of payroll and related costs for development personnel and external consulting costs associated with the development and maintenance of our products. Research and development costs, including the costs of developing computer software, are charged to operations as they are incurred. Research and development expenses decreased by $2.0 million, or 12.7%, to $13.6 million for the year ended December 31, 2008 from $15.6 million for the year ended December 31, 2007. This decrease was principally comprised of a $3.4 million reduction in consulting costs, which resulted from the ramp-down of resources originally retained for the development of our since-released next generation products for our health and life sciences segment, partially offset by a $1.3 million increase in salary and related costs, resulting from increases in average headcount of US and offshore employees of 7 and 21 employees, respectively, and severance costs incurred in the 2^nd quarter of 2008. The increase in US headcount is mostly attributable to the acquisitions of the ClaimRight business and Edge Dynamics, while the offshore headcount increase is related to the increased staffing of our new development office in India. As a percentage of total net revenues, research and development expense increased to 39.7% in 2008 versus 38.5% in 2007. Management expects research and development costs to be lower in 2009 versus 2008, both in absolute terms and as a percentage of revenue, as a result of (i) our elimination of 14 of 50 US-based engineering positions in December 2008 and January 2009, (ii) the concurrent termination of consulting agreements with most of our outside contractors, and (iii) the restructuring of our technical support organization which will result in larger allocations of engineering costs to the customer support function.

GENERAL AND ADMINISTRATIVE. General and administrative expenses consist primarily of salaries and related costs for personnel in our administrative, finance, legal and human resources departments, insurance costs, and legal, accounting and other professional service fees. General and administrative expenses decreased by $564,000, or 9.0%, to $5.7 million for the year ended December 31, 2008 from $6.2 million for the year ended December 31, 2007. This reduction in general and administrative expenses was primarily attributable to decreases of (i) $372,000 in salary and related costs, which was principally comprised of reduced senior management bonuses, a direct result of the lower sales and earnings results in 2008, and (ii) $333,000 in non-cash stock compensation. As a percentage of total net revenues, general and administrative expenses increased to 16.5% for the year ended December 31, 2008 from 15.4% for the year ended December 31, 2007.

DEPRECIATION. Depreciation expense increased by $263,000, or 29.5%, to $1.2 million in the year ended December 31, 2008 from $891,000 in the year ended December 31, 2007. This increase is principally attributable to (i) higher levels of spending for furniture, equipment and software additions in the year 2007 ($1.1 million) relative to the year 2004 ($698,000), the majority of these asset additions being depreciated over a three-year life, and (ii) depreciation on property and equipment acquired as part of the Edge Dynamics acquisition.

IN-PROCESS RESEARCH AND DEVELOPMENT. In connection with the acquisitions of the ClaimRight business in February 2008 and Edge Dynamics in May 2008, we allocated a total $1.6 million of the respective purchase considerations to in-process research and development, which was expensed upon consummation of the acquisitions. The allocations were based on appraisals conducted for the purpose of allocating initial consideration to the tangible and intangible assets acquired and liabilities assumed.

RESTRUCTURING AND OTHER CHARGES. In the quarter ended December 31, 2008, we incurred $641,000 in severance charges in connection with the elimination of 49 positions out of a total pre-downsizing headcount of 209. Also, in conjunction with our announced plan to move our United Kingdom operation to a smaller and less expensive facility, we vacated our office in London, England and accrued $216,000 in lease loss costs, such amount being based on our determination of the fair value of the remaining liability of the unused space (net of estimated sublease rental proceeds) as of December 31, 2008. The remaining $43,000 in restructuring charges was comprised of the amortization of the discount incorporated in the initial restructuring provisions for future lease costs in connection with the Chicago and London office downsizings, which occurred in 2003. In the year ended December 31, 2007, we recorded $93,000 of restructuring charges in connection with the 2003 office closings.

In the year ended December 31, 2008, interest expense of $1.6 million was comprised principally of $1.5 million of interest and amortization incurred in connection with the convertible notes payable we issued on December 31, 2007, and, to a lesser extent, $83,000 in financing fees incurred in connection with capital lease obligations. In the year ended December 31, 2007, interest expense of $122,000 consisted primarily of financing fees incurred in connection with capital lease obligations.

In the year ended December 31, 2008, other income, net of $412,000 was primarily comprised of interest income of $420,000. In year ended December 31, 2007, other income, net of $565,000 was mostly comprised of $543,000 of interest income. The decrease in interest income in the year ended December 31, 2008 versus the year earlier period was entirely attributable to a significant decrease in interest rate yields, partially offset by an increase in average invested balance resulting from the convertible notes payable financing in December 2007.

We incurred operating losses for all quarters in 2008 and 2007 and have consequently recorded a valuation allowance for the full amount of our net deferred tax asset, which consists principally of our net operating loss carryforwards. No provision or benefit for income taxes was recorded for the years ended December 31, 2008 and 2007.

Net revenues increased by $11.0 million, or 37.1%, to $40.6 million for the year ended December 31, 2007 from $29.6 million for the year ended December 31, 2006. Recurring revenue increased by $3.9 million, or 24.4%, to $19.7 million for the year ended December 31, 2007 from $15.9 million in the same period a year earlier, primarily attributable to increases of (i) $2.3 million, or 92.7%, in subscription revenue in our health and life sciences segment and (ii) $1.2 million, or 15.1%, in maintenance and support revenues in our health and life sciences segment, which was attributable to continued growth in our maintenance-paying, installed customer base in that segment. As indicated above in this Item 7, subscription arrangements have represented a substantial proportion of license contracts since their introduction in 2004 and our recognized subscription revenues have increased significantly during this period. Service revenue increased by $1.4 million, or 11.3%, to $13.5 million in the year ended December 31, 2007 versus $12.1 million in 2006. The 2007 amount included $1.8 million in previously-deferred service revenues for work performed in prior reporting periods. Excluding the catch-up deferral recognition, service revenues were lower relative to 2006 due to a significant decrease in billable consulting work performed in our industry solutions segment. License revenues increased by $5.7 million, or 359.1%, to $7.3 million for the year ended December 31, 2007 from $1.6 million in 2006.

As indicated in the table below, the gross value of license contracts sold during 2007 increased by 17.5% versus 2006, due primarily to an increase in the number of license transactions (minimum value of $50,000) from 29 to 35. License revenue during 2007 included $2.7 million of previously-deferred revenues in connection with license agreements sold in prior periods, as compared to no recognition of any such deferred revenues during 2006. Also, while most of the license transactions executed in both 2006 and 2007 were either accounted for as subscription arrangements or had conditions such as software acceptance testing which resulted in deferral of license revenue recognition, the proportion of transactions represented by such deals was smaller in 2007 which contributed to the increase in license revenue versus 2006.

Reconciliation of Value of License Transactions to Reportable License Revenue

The above financial information is provided as additional information and is not in accordance with or an alternative to generally accepted accounting principles, or GAAP. See discussion following the reconciliation table in “Results of Operations—Year Ended December 31, 2008 Compared to Year Ended December 31, 2007—Net Revenues” in this Item 7.

Total net revenues derived from our health and life sciences segment increased by $9.5 million, or 43.3%, to $31.4 million for the year ended December 31, 2007 from $21.9 million in the prior year. Essentially all revenue sources contributed to this segment’s performance with the principal increases being: (i) $4.5 million, or 290.1%, in license fees, (ii) $2.3 million, or 92.7%, in subscriptions, (iii) $1.5 million, or 16.3%, in professional services, and (iv) $1.2 million, or 15.1%, in non-subscription maintenance and support. As indicated in the above table, the gross values of license contracts sold in this segment during the year ended December 31, 2007 increased by $3.1 million, or 25.0%, versus 2006 due primarily to an increase in the number of license transactions. Segment license revenue during the year ended December 31, 2007 included $1.8 million of previously-deferred revenues in connection with license agreements sold in prior periods. Approximately one-third of the increase in services revenue was comprised of current year recognition of previously-deferred consulting work, with the balance of the increase mostly attributable to higher demand for consulting work in connection with changes in government

regulation (i.e., the Deficit Reduction Act of 2005). The increase in maintenance and support revenue relative to the prior year was attributable primarily to growth in our installed maintenance-paying customer base, particularly in connection with our recent releases of the I-many Contract Management Suite for Life Sciences™, and to a lesser extent a non-recurring $328,000 back maintenance charge to a single customer.

Total net revenues derived from the industry solutions segment increased by $1.5 million, or 19.6%, to $9.2 million for the year ended December 31, 2007 from $7.7 million in 2006. This increase was attributable to the recognition of $2.1 million in previously-deferred revenues in connection with license agreements and related services sold in prior years. Excluding the catch-up deferral recognition, professional services revenues in this segment were lower in 2007 versus 2006 by $1.0 million. As indicated in the above table, the gross value of license contracts sold in this segment during 2007 decreased by $590,000, or 30.0%, versus 2006, continuing a trend of declining annual licensing activity that began in 2003, and this trend has been a key contributor to the decline in professional services revenue opportunities. Licensing activity in the industry solutions segment has been negatively affected by product defect issues in one of our key software products (see “Critical Accounting Policies – Revenue Recognition” in this Item 7 above) and management is uncertain as to when it expects licensing activity in this segment to begin growing.

COST OF RECURRING REVENUE. Cost of recurring revenue for the year ended December 31, 2007 was unchanged at $6.4 million versus the year ended December 31, 2006. Increases of $409,000 in salary and related costs, resulting principally from merit increases and an increase in average headcount of 3 employees, and $63,000 in noncash stock compensation was entirely offset by a $328,000 decrease in consulting fee expenses and sundry other expense reductions. As a percentage of recurring revenue, cost of recurring revenue decreased to 32.2% for the year ended December 31, 2007 from 40.1% for the year ended December 31, 2006, with this decrease being entirely attributable to higher recurring revenue in 2007.

COST OF SERVICES REVENUE. Cost of services revenue increased by $445,000, or 4.2%, to $11.0 million in the year ended December 31, 2007 from $10.6 million in the year ended December 31, 2006. This increase is principally attributable to increases of (i) $360,000 in the cost of consultants, resulting from the need to augment our professional services staff on certain implementation engagements, (ii) $254,000 in salary and related costs, primarily due to annual merit increases, and (iii) $111,000 in noncash stock compensation costs, partially offset by a $263,000 decrease in travel expenses. As a percentage of service revenues, cost of services revenue decreased to 81.8% for the year ended December 31, 2007 from 87.3% for the year ended December 31, 2006.

COST OF THIRD PARTY TECHNOLOGY. Cost of third party technology increased by $31,000, or 12%, to $300,000 for the year ended December 31, 2007 from $269,000 in the year ended December 31, 2006. This increase was attributable to the accelerated amortization of certain prepaid royalty amounts since sales of our products which require payments of royalties to third parties actually decreased from the prior year.

AMORTIZATION OF OTHER ACQUIRED INTANGIBLE ASSETS. Amortization of acquired intangible assets related to our acquisitions amounted to $185,000 in the year ended December 31, 2007, which represents a $297,000, or 62%, decrease in amortization from the prior year. This decrease is attributable to the intangible assets in connection with the acquisitions of NetReturn, LLC and Menerva Technologies, Inc. becoming fully-amortized during the first quarter of 2006.

SALES AND MARKETING. Sales and marketing expense increased by $756,000, or 8.1%, to $10.1 million in the year ended December 31, 2007 from $9.3 million in the year ended December 31, 2006. This increase is primarily attributable to a $543,000 increase in commission costs, resulting primarily from a 17.5% increase in the gross value of license contracts sold in 2007 versus 2006 and to an increase in draw payments instituted as part of a sales staff retention plan. Also, salary costs increased by $314,000 in 2007 as compared to

the prior year due to a change in the headcount mix to more highly-compensated employees. As a percentage of total net revenues, sales and marketing expense decreased to 24.9% in 2007 versus 31.5% in 2006.

RESEARCH AND DEVELOPMENT. Research and development expenses increased by $3.0 million, or 24.2%, to $15.6 million for the year ended December 31, 2007 from $12.6 million for the year ended December 31, 2006. This increase was principally comprised of increases of (i) $1.1 million in consulting costs, (ii) $1.1 million in salary and related costs, resulting from merit increases, higher staff levels, and one-time severance payments, and (iii) $259,000 in noncash stock compensation costs. The increases in salary-related and consulting costs were mostly attributable to our ramping up resources for the development of next generation products for our health and life sciences segment, which were released in late December 2007. As a percentage of total net revenues, research and development expense decreased to 38.5% in 2007 versus 42.6% in 2006 because of the relatively larger increase in net revenues relative to the prior year. Our spending on research and development expenses reached its highest point since our initial public offering in 2000 in both absolute terms and as a percentage of revenue during the first quarter of 2007. Subsequently, spending levels decreased an average of 6.8% per quarter through the end of 2007, with spending as a percentage of revenues during the fourth quarter of 2007 reaching its second lowest level since the first quarter of 2002.

GENERAL AND ADMINISTRATIVE. General and administrative expenses increased by $792,000, or 14.5%, to $6.2 million for the year ended December 31, 2007 from $5.4 million for the year ended December 31, 2006. This increase in general and administrative expenses was primarily attributable to increases of (i) $414,000 in salary and related costs, which was caused by higher executive bonus payments and merit pay increases, and (ii) $337,000 in noncash stock compensation costs, resulting mostly from stock option grants to our chief executive officer. As a percentage of total net revenues, general and administrative expenses decreased to 15.4% for the year ended December 31, 2007 from 18.4% for the year ended December 31, 2006.

DEPRECIATION. Depreciation expense increased by $67,000, or 8%, to $891,000 in the year ended December 31, 2007 from $824,000 in the year ended December 31, 2006. This increase is principally attributable to an increase in the level of furniture, equipment and software additions to $1.0 million in 2007 as compared to annual average additions of $785,000 for the years 2004 through 2006.

RESTRUCTURING AND OTHER CHARGES. In the year ended December 31, 2007, we recognized $93,000 in charges related to efforts in prior years to streamline operations. This charge represents the amortization of the discount incorporated in the initial restructuring provisions for future lease costs in connection with the Chicago and London office downsizings, which occurred in 2003. In the year ended December 31, 2006, we recorded $103,000 in such charges.

Other income, net, decreased by $142,000, or 24%, to $443,000 in the year ended December 31, 2007 versus $585,000 in 2006. The combination of a reduction in interest income of $111,000 and an increase in interest expense of $109,000 was partially offset by $26,000 in higher net foreign currency gains and a decrease in state franchise tax payments of $36,000. The reduction in interest income resulted from lower investable cash balances during 2007 and a drop in interest rates. The increase in interest expense was mostly attributable to a prior year sales tax assessment.

We incurred operating losses for all quarters in 2007 and 2006 and consequently recorded a valuation allowance for the full amount of our net deferred tax asset, which consists principally of our net operating loss carryforwards. No provision or benefit for income taxes was recorded for the years ended December 31, 2007 and 2006.

The accompanying financial statements have been prepared on a going concern basis, which contemplates the realization of assets and the satisfaction of liabilities in the ordinary course of business. As shown in the accompanying financial statements and in our previous filings on Form 10-K, we have incurred recurring losses from operations, and as of December 31, 2008 our total liabilities exceeded our total assets by $8.7 million. Also, as indicated in Note 4 to our consolidated financial statements in Item 8, our common stock is at risk of being delisted from the NASDAQ Capital Market, which would cause our senior convertible notes to be in default. These factors raise substantial doubt about our ability to continue as a going concern.

On December 31, 2007, we completed a private placement of $17.0 million of senior convertible notes (“Notes”), which resulted in our receipt of approximately $16.9 million in net proceeds in 2007. An additional $1.1 million in debt issuance costs were incurred and paid in 2008. The Notes bear interest at 6.5% per annum, payable quarterly in arrears, and will mature on December 31, 2012. The notes are redeemable at par by the investors on December 31, 2010 and by the Company at any time beginning December 31, 2010. See Note 4 to the consolidated financial statements. The Company has used proceeds from the sale of the Notes for the ClaimRight and Edge Dynamics acquisitions (see Note 3 to the consolidated financial statements) and is using the remaining proceeds from the sale of the Notes for general corporate and working capital purposes. As discussed more fully in the notes to our consolidated financial statements, the Notes would be in default, and the holders of the Notes could require the Company to redeem the Notes for their principal amount and accrued interest, if the Company’s common stock is delisted from the NASDAQ Capital Market.

On November 6, 2006, we completed a private placement of our common stock and warrants, which resulted in our receipt of approximately $6.5 million in net proceeds.

In 2007 and 2008, we entered into several capital lease financing arrangements with different financial institutions in order to finance the purchase of computer equipment, software and related services amounting to $403,000 and $550,000, respectively.

At December 31, 2008, we had cash and cash equivalents of $9.3 million, as compared to cash and cash equivalents of $28.6 million at December 31, 2007. Also at December 31, 2008, we had $17.0 million in convertible notes payable outstanding. The current and non-current restricted cash balances of $80,000 and $199,000, respectively, at December 31, 2008 represent cash amounts held on deposit as security on two long-term real property lease obligations.

Net cash used in operating activities for the year ended December 31, 2008 was $13.0 million, as compared to net cash used in operating activities of $5.2 million in the year ended December 31, 2007. For the year ended December 31, 2008, net cash used in operating activities resulted principally from our net loss of $15.6 million – as reduced by non-cash items (i) depreciation and amortization of $1.6 million, (ii) in-process research and development of $1.6 million, (iii) stock-based compensation of $2.0 million, and (iv) restructuring charges of $900,000, and decreases in accrued expenses and deferred revenue of $4.1 million and $1.1 million, respectively—partially offset by a $1.7 million decrease in accounts receivable. The $4.1 million decrease in accrued expenses was principally attributable to several items: (a) payments during the quarter ended June 30, 2008 of $1.9 million of accrued expenses (mostly bonus and severance payments) that had been assumed from the acquisition of Edge Dynamics, (b) a $730,000 decrease in the management bonus accrual resulting primarily from the 2007 year end bonus payouts in February 2008 and a reduction in 2008 year-to-date accruals because of lower-than-expected sales and earnings results, (c) a $438,000 decrease in accrued commissions largely attributable to lower license bookings in 2008 versus 2007, and (d) final settlement and payment of $345,000 in costs related to the annual user conference held in November 2007. The $1.1 million decrease in deferred revenue was primarily attributable to a $1.6 million decrease in the value of deferred subscription fees, which was due principally to (i) the acceleration into revenue of $772,000 in deferred license fees that previously had been accounted for as subscription agreements for accounting purposes, such acceleration being triggered by

certain contractual changes in the underlying agreements that were executed in June 2008 and (ii) a significant drop in sales of subscription arrangements during 2008, partially offset by a $761,000 increase in deferred license fees. The $1.7 million reduction in accounts receivable was primarily attributable to (i) $1.2 million in receivables assumed in the acquisition of Edge Dynamics, most of which was realized into cash during 2008, and (ii) a $875,000 decrease in non-subscription license sales in the quarter ended December 31, 2008 versus the last quarter of 2007.

For the year ended December 31, 2007, net cash used in operating activities resulted principally from our net loss of $9.8 million—as reduced by non-cash items depreciation and amortization of $1.1 million and stock-based compensation of $2.4 million, and a $1.7 million decrease in deferred revenue—partially offset by a $1.5 million decrease in accounts receivable and a $973,000 increase in accrued expenses. The $1.7 million decrease in deferred revenue was primarily attributable to the recognition into revenue during 2007 of $2.7 million in previously-deferred license fees (see table under “Results of Operations—Year Ended December 31, 2007 Compared to Year Ended December 31, 2006—Net Revenues” in this Item 7), partially offset by a $696,000 increase in deferred subscription fees, which is a result of the increased demand for subscription license arrangements. The $1.4 million decrease in accounts receivable was principally attributable to strong collection experience as Days Sales Outstanding decreased significantly from 96 days at December 31, 2006 to 52 days at December 31, 2007. The $973,000 increase in accrued expenses was mostly comprised of higher bonus accruals and an increase in sales taxes accrued.

In the year ended December 31, 2008, net cash used in investing activities of $4.8 million consisted of (i) $2.3 million paid to acquire Edge Dynamics, (ii) $1.8 million paid to acquire the ClaimRight business and (iii) $710,000 of property and equipment additions. In the year ended December 31, 2007, net cash used in investing activities was comprised solely of $641,000 in property and equipment additions.

Net cash used in financing activities was $1.4 million in the year ended December 31, 2008, principally comprised of $1.1 million in payments of debt issuance costs in connection with our December 2007 issuance of convertible Notes and $512,000 in payments of capital lease obligations, as compared to cash provided of $17.2 million in the year ended December 31, 2007, which consisted primarily of $17.0 million in proceeds from the private placement issuance of our convertible Notes.

We currently anticipate that our cash and cash equivalents of $9.3 million will be sufficient to meet our anticipated needs for working capital and capital expenditures for at least the next 12 months. However, this cash balance is not sufficient to redeem the $17.0 million in outstanding principal of our convertible Notes, payment of which could become due if our common stock is delisted from the NASDAQ Capital Market. On October 21, 2008, we received notice from NASDAQ that the market value of our listed securities had been below the required minimum $35 million for the previous ten consecutive business days, and that if the market value of our listed securities did not exceed $35 million for a minimum of ten consecutive business days at any time prior to November 20, 2008, our common stock would be delisted subject to our right to a hearing before a NASDAQ Listing Qualifications Panel. We received this delisting notice on November 24, 2008. We requested a hearing and, on January 8, 2009, presented our plan to the Panel for regaining compliance with all applicable requirements for continued listing. On March 20, 2009, the Company received notification from the Panel that it had determined to grant the Company’s request to remain listed on the NASDAQ Capital Market, subject to the condition that, among other things, the Company evidence stockholders’ equity at or above $2.5 million on or before May 26, 2009. The Panel reserves the right to reconsider the terms of this exception under circumstances that make continued listing of the Company’s common stock on the NASDAQ Capital Market unwarranted. While the Company is working to regain compliance, there can be no assurance that the Company will be able to regain compliance by the deadline established by the Panel.

The delisting of our common stock from the NASDAQ Capital Market is an event of default under the Notes. The terms of the Notes require the Company to list and maintain its common stock on either the New York Stock Exchange, the NYSE Alternext US Market (formerly the American Stock Exchange), the NASDAQ

Global Select Market, the NASDAQ Global Market or the NASDAQ Capital Market (collectively defined in the Notes as “Eligible Markets”). Our common stock is currently listed on the NASDAQ Capital Market, and it does not currently meet the initial quantitative listing requirements of the other Eligible Markets. We have initiated discussions to seek a waiver of this default from the holders of the Notes; however, there can be no assurance that we will be able to obtain a waiver on favorable terms, if at all. If we are unable to obtain a waiver, we would be unable to repay the Notes without raising additional capital and our ability to continue as a going concern would be in significant doubt.

Also, our future long-term capital needs will depend significantly on the rate of growth of our business, our rate of loss, the mix of subscription licensing arrangements versus perpetual licenses sold, possible acquisitions, the timing of expanded product offerings and the success of these offerings if and when they are launched. Accordingly, any projections of future long-term cash needs and cash flows are subject to substantial uncertainty. If we need to raise capital to repay the Notes, or if our current balance of cash and cash equivalents is otherwise insufficient to satisfy our liquidity needs, we may seek to sell additional equity or debt securities to raise funds, and those securities may have rights, preferences or privileges senior to those of the rights of our common stock. In connection with a sale of stock, our stockholders would experience dilution. In addition, we cannot be certain that additional financing will be available to us on favorable terms when required, or at all. Also, our stock price and current economic conditions may make it difficult for us to raise additional equity financing.

Our exposure to market risk for changes in interest rates relates primarily to our investment portfolio. We do not use derivative financial instruments in our investment portfolio. The primary objective of our investment activities is to preserve principal while maximizing yields without assuming significant risk. This is accomplished by investing in diversified investments, consisting primarily of short-term investment-grade securities. Due to the nature of our investments, we believe there is no material risk exposure. A hypothetical 100 basis point change in interest rates, either positive or negative, would not have had a significant effect on either (i) our cash flows and reported net losses in the years ended December 31, 2006, 2007 and 2008, or (ii) the fair value of our investment portfolio at December 31, 2007 and 2008.

As of December 31, 2007 and 2008, our cash and cash equivalents consisted entirely of money market investments and short-term commercial paper with remaining maturities of 90 days or less when purchased and non-interest bearing checking accounts. Investments in marketable debt securities with maturities greater than 90 days and less than one year are classified as held-to-maturity short-term investments and are recorded at amortized cost. Under current investment guidelines, maturities on short-term investments are restricted to one year or less. At December 31, 2007 and 2008, we held no such short-term investments. Investments in auction rate securities, with maturities which can be greater than one year but for which interest rates reset in less than 90 days, are classified as available for sale securities and have been stated at fair market value. At December 31, 2007 and 2008, we held no auction rate certificates, having disposed of all our previous holdings in such investments during 2005.

As of December 31, 2007 and 2008, our outstanding debt consisted entirely of senior convertible notes of $17.0 and $17.0 million, respectively, and capital lease obligations of $573,000 and $611,000, respectively. The interest rates on the convertible notes (6.5%) and our various capital lease obligations (6.6% – 15.2%) are fixed, so we are not currently exposed to risk from changes in interest rates. A hypothetical 100 basis point increase in interest rates would not have had a significant effect on our annual interest expense.

We operate in certain foreign locations, where the currency used is not the U.S. dollar. However, these locations have not been, and are not currently expected to be, significant to our consolidated financial statements. Changes in exchange rates have not had a material effect on our business.

We have audited the accompanying consolidated balance sheets of I-many, Inc. as of December 31, 2008 and 2007 and the related consolidated statements of operations, stockholders’ equity (deficit), and cash flows for each of the three years in the period ended December 31, 2008. These financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on these financial statements based on our audits.

We conducted our audits in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements, assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements. We believe that our audits provide a reasonable basis for our opinion.

In our opinion, the consolidated financial statements referred to above present fairly, in all material respects, the financial position of I-many, Inc. at December 31, 2008 and 2007, and the results of its operations and its cash flows for each of the three years in the period ended December 31, 2008, in conformity with accounting principles generally accepted in the United States of America.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), I-many, Inc.’s internal control over financial reporting as of December 31, 2008, based on criteria established in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (COSO) and our report dated March 30, 2009 expressed an unqualified opinion thereon.

The accompanying financial statements have been prepared assuming that the Company will continue as a going concern. As discussed in Note 1 to the financial statements, the Company has suffered recurring losses from operations and has a net capital deficiency that raise substantial doubt about its ability to continue as a going concern. Management’s plans in regard to these matters are also described in Note 1. The financial statements do not include any adjustments that might result from the outcome of this uncertainty.

We have audited I-many, Inc.’s internal control over financial reporting as of December 31, 2008, based on criteria established in Internal Control—Integrated Framework issued by the Committee of Sponsoring Organizations of the Treadway Commission (the COSO criteria). I-many, Inc.’s management is responsible for maintaining effective internal control over financial reporting and for its assessment of the effectiveness of internal control over financial reporting, included in the accompanying “Item 9A, Management’s Report on Internal Control Over Financial Reporting”. Our responsibility is to express an opinion on the Company’s internal control over financial reporting based on our audit.

We conducted our audit in accordance with the standards of the Public Company Accounting Oversight Board (United States). Those standards require that we plan and perform the audit to obtain reasonable assurance about whether effective internal control over financial reporting was maintained in all material respects. Our audit included obtaining an understanding of internal control over financial reporting, assessing the risk that a material weakness exists, and testing and evaluating the design and operating effectiveness of internal control based on the assessed risk. Our audit also included performing such other procedures as we considered necessary in the circumstances. We believe that our audit provides a reasonable basis for our opinion.

A company’s internal control over financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted accounting principles. A company’s internal control over financial reporting includes those policies and procedures that (1) pertain to the maintenance of records that, in reasonable detail, accurately and fairly reflect the transactions and dispositions of the assets of the company; (2) provide reasonable assurance that transactions are recorded as necessary to permit preparation of financial statements in accordance with generally accepted accounting principles, and that receipts and expenditures of the company are being made only in accordance with authorizations of management and directors of the company; and (3) provide reasonable assurance regarding prevention or timely detection of unauthorized acquisition, use, or disposition of the company’s assets that could have a material effect on the financial statements.

Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Also, projections of any evaluation of effectiveness to future periods are subject to the risk that controls may become inadequate because of changes in conditions, or that the degree of compliance with the policies or procedures may deteriorate. In our opinion, I-many, Inc. maintained, in all material respects, effective internal control over financial reporting as of December 31, 2008, based on the COSO criteria.

We also have audited, in accordance with the standards of the Public Company Accounting Oversight Board (United States), the accompanying consolidated balance sheets of I-many, Inc. as of December 31, 2008 and 2007 and the related consolidated statements of operations, stockholders’ equity (deficit), and cash flows for the three years in the period ended December 31, 2008 and our report dated March 30, 2009 expressed an unqualified opinion thereon, and such report included an explanatory paragraph on the Company’s ability to continue as a going concern.

I-many, Inc. (the “Company”) provides software solutions and related professional services that allow customers to manage their contract-based, business-to-business relationships through the entirety of the contract management lifecycle. Historically, the Company’s primary customer base has included parties involved in the sale and distribution of pharmaceutical and other healthcare products, including manufacturers, purchasers, groups of purchasers and distributors. The Company has since expanded the market reach of its product offerings, with customers in the consumer products, foodservice, and other industries.

The accompanying financial statements have been prepared on a going concern basis, which contemplates the realization of assets and satisfaction of liabilities in the ordinary course of business. As shown in the accompanying financial statements and in its previous filings on Form 10-K, the Company has incurred recurring losses from operations, and as of December 31, 2008 the Company’s total liabilities exceeded its total assets by $8.7 million. Also, as indicated in note 4 below, the Company’s common stock is at risk of being delisted from the NASDAQ Capital Market, which would cause the Company’s $17 million of senior convertible notes to be in default. In the event the Company’s common stock is delisted and these notes are called, the Company does not have sufficient funds to pay off these notes. These factors raise substantial doubt about the Company’s ability to continue as a going concern. As indicated in note 12 below, the Company implemented a significant restructuring of its operations in the fourth quarter of 2008, after having previously instituted a cost reduction program which included a reduction in headcount and consulting costs in the second quarter of 2008. Although there is no assurance that such restructuring will be successful, Company management believes that these two cost reduction programs have reduced the company’s break-even revenue point to an achievable level. Also, Company management is currently investigating options for regaining compliance with the listing requirements of the NASDAQ Capital Market to avoid default of its notes. The financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern.

The consolidated financial statements include the accounts of the Company and its wholly owned subsidiaries. All significant intercompany accounts and transactions have been eliminated in consolidation.

The preparation of financial statements in conformity with accounting principles generally accepted in the United States of America requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period. Actual results could differ from those estimates. Major assets and liabilities that are subject to estimates include allowance for doubtful accounts, goodwill and other acquired intangible assets, deferred tax assets and certain accrued and contingent liabilities.

The Company recognizes revenue in accordance with Statement of Position (SOP) 97-2, “Software Revenue Recognition,” and SOP 98-9, “Software Revenue Recognition, with Respect to Certain Arrangements.” Software license fees are recognized upon execution of a signed license agreement and delivery of the software to customers, provided there are no significant post-delivery obligations, the payment is fixed or determinable and collection is probable. In multiple-element arrangements, a portion of the total fee is allocated to the undelivered professional services, training and maintenance and support services based on the fair value of those elements, which is defined as the price charged when those elements are sold separately. The residual amount is then

allocated to the software license fee. In cases where the Company agrees to deliver unspecified additional products in the future, the license fee is recognized ratably over the term of the arrangement beginning with the delivery of the first product. In cases where the Company agrees to deliver specified additional products or upgrades in the future, recognition of the entire license fee, including any related maintenance and support fees, is deferred until after the specified additional products or upgrades are delivered and made generally available to all customers. If an acceptance period is required, revenues are deferred until customer acceptance. In cases where collection is not deemed probable, we recognize the license fee as payments are received. In cases where significant production or customization is required prior to attaining technological feasibility of the software, license fees are recognized on a percentage-of-completion basis and are credited to research and development expenses as a funded development arrangement. After the software attains technological feasibility, recognizable license fees are reported as product revenue.

In 2007, the Company began to classify its reported net revenues into three revenue categories – Recurring, Services and License revenues – after having previously reported its revenues as being either Product or Service. Recurring revenue consists of (i) fees generated from the provision of maintenance, support, and hosting services and (ii) subscription revenues. Services revenue is now comprised of professional service and training fees and reimbursable out-of-pocket expenses. License revenue consists of non-recurring license fees generated from perpetual license agreements.

Current and prospective customers have the option of entering into a subscription agreement as an alternative to the Company’s standard perpetual license contract model. The standard subscription arrangement is presently a fixed fee agreement over three or more years, covering license fees, unspecified new product releases and maintenance and support, generally payable in equal quarterly or annual installments commencing upon execution of the agreement. Prior to 2006, more than half of the executed subscription arrangements included a provision allowing the agreement to convert free-of-charge to a perpetual license after the completion of the initial term plus any extensions, generally after five years, after which time the customer would have the option of paying for the continuation of maintenance and support. Beginning in 2006, the Company has generally discontinued including free-of-charge perpetual conversion provisions in new subscription arrangements. Also included in subscription revenues are license fees generated from perpetual license arrangements with rights to unspecified additional products, which are treated as subscription arrangements for accounting purposes. For subscription arrangements which include rights to specified products which are not yet generally available to customers, revenue recognition is deferred until all elements of the arrangement including any such specified products have been delivered. For all other subscription arrangements, the Company recognizes all revenue ratably over the term of the subscription agreement commencing upon delivery of the initial product. Subscription installment amounts that are not yet contractually billable to customers are not reflected in deferred revenues on the Company’s consolidated balance sheet.

Maintenance and support fees are recognized ratably over the term of the service period, which is generally twelve months. When maintenance and support is included in the total license fee, a portion of the total fee is allocated to maintenance and support based upon the price paid by the customer when sold separately, generally as renewals in the second year.

Professional service revenues are recognized as the services are performed. If conditions for acceptance exist, professional service revenues are recognized upon customer acceptance. For fixed fee professional service contracts that fall under SOP 81-1, “Accounting for Performance of Construction-Type and Certain Production-Type Contracts,” anticipated losses are provided for in the period in which the loss is probable and can be reasonably estimated. Training revenues are recognized as the services are provided. Included in training revenues are registration fees received from participants in the Company’s annual off-site user training conferences.

Payments received from customers at the inception of a maintenance period are treated as deferred service revenues and recognized ratably over the maintenance period. Payments received from customers in advance of product shipment or revenue recognition are treated as deferred revenues and recognized when the product is shipped to the customer or when otherwise earned.

During the third quarter of 2005, the Company became aware of certain defects in the then current version of one of its software products, which was first shipped to customers in the fourth quarter of 2004. These defects, which were not identified in pre-release product testing, affected the performance of the software for a portion of the Company’s customers depending on each customer’s particular implementation environment and its intended use of the software. Because certain concessions have been made to customers in connection with these defects, the Company had generally elected not to recognize revenue from sales of this software product and related implementation services since the third quarter of 2005, except in those cases in which it was determined that the customer was not likely to be affected by the known, unresolved software defects. During 2006, new versions of the software were released, but problems continued to occur with implementations at several customer sites. In 2007, the Company released new versions of the software which were designed to resolve known performance defects with minimal additional functionality. Also during 2007, the Company successfully completed implementations of the newest version of this software at multiple customer sites and made progress with other customer implementations, and accordingly has begun recognizing revenue from this software on a limited basis. However, the Company is continuing to defer all recurring, services and license revenue in connection with (i) implementations of this software program that are not yet complete, and (ii) any customers for which a concession is probable and an agreement formalizing a concession amount has not been executed. As of December 31, 2007 and 2008, the Company has reversed and deferred cumulative amounts of $671,000 and $875,000, respectively, of otherwise-recognizable product and service revenue, based in part on its estimate of the fair value of concessions to be made until the remaining defects are resolved, and partly on its determination that license fees were not fixed and determinable because of the possibility of future concessions.

The Company’s agreements with customers generally include certain provisions for indemnifying the customer against losses, expenses, and liabilities from damages that may be awarded against the customer in the event that the Company’s products are found to infringe upon a patent, copyright, trademark, or other proprietary right of a third party. The agreements generally limit the scope of remedies for such indemnification obligations in a variety of industry-standard respects, including the Company’s right to replace an infringing product. To date, the Company has not had to reimburse any of its customers for any losses related to these indemnification provisions and no claims were outstanding as of December 31, 2007 and 2008. The Company does not expect that any significant impact on financial position or the results of operations will result from these indemnification provisions.

Goodwill is tested for impairment at the reportable segment level, which is the same as the reporting unit level, using a two-step approach. The first step compares the fair value of a reporting unit to its carrying amount, including goodwill. If the fair value of the reporting unit is greater than its carrying amount, goodwill is not considered impaired and the second step is not required. If the fair value of the reporting unit is less than its carrying amount, the second step of the impairment test measures the amount of the impairment loss, if any, by comparing the implied fair value of goodwill to its carrying amount. If the carrying amount of goodwill exceeds its implied fair value, an impairment loss is recognized equal to that excess. The implied fair value of goodwill is calculated in the same manner that goodwill is calculated in a business combination, whereby the fair value of the reporting unit is allocated to all of the assets and liabilities of that unit (including any unrecognized intangible assets), with the excess purchase price over the amounts assigned to assets and liabilities representing the implied fair value of goodwill. Goodwill is tested for impairment at least annually, or on an interim basis if an event occurs or circumstances change that would likely reduce the fair value of a reporting unit below its carrying value.

The Company considers all highly liquid securities with remaining maturities of 90 days or less when purchased to be cash equivalents. Cash equivalents are stated at cost, which approximates fair value, and primarily consist of money market funds and overnight investments that are readily convertible to cash.

Restricted cash comprises amounts held in deposits that were required as collateral under the lease of office space in the Company’s former London office, and the sublease of unused office space in the Company’s former Chicago office.

Property and equipment are recorded at cost. Depreciation and amortization are computed using the straight-line method over the estimated useful lives of the assets, which are indicated in the table below. Repair and maintenance costs are expensed as incurred.

Debt issuance costs are amortized into interest expense using the effective interest method over the period leading up to the earlier of (i) the maturity date of the debt or (ii) the earliest date at which the debt is redeemable at par by the creditors. Debt issuance costs net of amortization are included in deferred charges and other assets in the Consolidated Balance Sheets.

Long-lived assets are reviewed for impairment on an annual basis, or on an interim basis if an event or circumstance occurs between annual tests indicating that the assets might be impaired. The impairment test consists of comparing the asset’s carrying amount to the related undiscounted future cash flows. If the fair value is less than the carrying amount, an impairment loss is recognized in an amount equal to that difference.

All research and development costs are expensed as incurred. Costs eligible for capitalization under Statement of Financial Accounting Standards No. 86, “Accounting for the Costs of Computer Software to Be Sold, Leased, or Otherwise Marketed,” were not material to our consolidated financial statements during the years ended December 31, 2006, 2007 and 2008.

Costs incurred for internal-use software during the preliminary project stage and costs incurred for data conversion, training and maintenance are expensed as incurred. Once the preliminary project stage is completed, external direct costs incurred during the application development stage are capitalized and amortized over the estimated useful life of the asset. There were no costs incurred for internal-use software during the years ended December 31, 2006, 2007 and 2008.

Financial instruments that potentially expose the Company to concentrations of credit risk consist of cash equivalents and accounts receivable. The Company believes the concentration of credit risk with respect to cash equivalents is limited because the Company places its investments in triple A rated overnight institutional money

market funds. Concentration of credit risk with respect to accounts receivable is limited to certain customers to whom the Company makes substantial sales. The Company generally requires no collateral. To reduce risk, the Company routinely assesses the financial strength of its customers and, as a consequence, believes that its accounts receivable credit risk exposure is limited. The Company maintains an allowance for doubtful accounts and estimated losses but historically has not experienced any significant losses related to individual customers or groups of customers in any particular industry or geographic area.

The Company had one customer whose accounts receivable balances, including unbilled receivables, individually represented 10% or more of the Company’s total accounts receivable, as follows:

None of the Company’s customers generated revenues which individually represented 10% or more of the Company’s total net revenues during the years ended December 31, 2006, 2007 or 2008.

In January 2008, the Company adopted Statement of Financial Accounting Standards No. 157 (or SFAS 157), “Fair Value Measurements”. This pronouncement defines fair value, establishes a framework for measuring fair value, and requires expanded disclosures about fair value measurements. SFAS 157 emphasizes that fair value is a market-based measurement, not an entity-specific measurement, and defines fair value as the price that would be received to sell an asset or transfer a liability in an orderly transaction between market participants at the measurement date. SFAS 157 discusses valuation techniques, such as the market approach (comparable market prices), the income approach (present value of future income or cash flow) and the cost approach (cost to replace the service capacity of an asset or replacement cost), which are each based upon observable and unobservable inputs. Observable inputs reflect market data obtained from independent sources, while unobservable inputs reflect the Company’s market assumptions. SFAS 157 utilizes a fair value hierarchy that prioritizes inputs to fair value measurement techniques into three broad levels:

The Company’s investment in overnight money market institutional funds, which amounted to $6.1 million at December 31, 2008, is included in cash and cash equivalents on the accompanying balance sheets and is classified as a Level 1 asset.

The carrying amounts of the Company’s other non-cash financial instruments, including its accounts receivable, accounts payable, accrued expenses, deferred revenue and capital lease obligations approximate their fair value due to the relatively short-term nature of these instruments.

Basic and diluted net loss per share is computed by dividing the net loss available to common stockholders for the period by the weighted average basic and diluted number of shares of common stock outstanding during

the period. The calculation of basic weighted average shares outstanding excludes unvested restricted common stock that is subject to repurchase by the Company. For periods in which a net loss has been incurred, the calculation of diluted net loss per share excludes potential common stock, as their effect is antidilutive. Potential common stock includes (i) incremental shares of common stock issuable upon the exercise of outstanding stock options and warrants calculated using the treasury stock method and (ii) unvested restricted common stock subject to repurchase by the Company.

Since the Company has incurred a net loss in all years presented, the calculation of diluted net loss per share excludes the following potential shares of common stock as their effect on net loss per share is antidilutive:

During 2003 and 2004, the Company closed its Chicago and India offices and downsized its operations in Portland, Maine and London, England as part of its efforts to reduce operating expenses and consolidate its operations. Total costs incurred related to these exit and disposal activities amounted to $103,000, $93,000 and $43,000, respectively, in 2006, 2007 and 2008. In December 2008, the Company implemented a significant restructuring of its operations in order to streamline operations and better align operating expense levels with a conservative revenue forecast for 2009. As part of this downsizing, the Company eliminated 49 employee positions, moved its London office to a smaller facility, and incurred $857,000 in severance charges and lease loss costs (see Note 12).

Statement of Financial Accounting Standard (“SFAS”) No. 130, “Reporting Comprehensive Income,” requires foreign currency translation adjustments and certain other items, which were reported separately in stockholders’ equity, to be included in accumulated other comprehensive income (loss). Total comprehensive loss for the years ended December 31, 2006, 2007 and 2008 is comprised of the following:

In June 2006, the Financial Accounting Standards Board (“FASB”) issued Interpretation No. 48 (“FIN 48”) regarding “Accounting for Uncertainties in Income Taxes,” which defines the threshold for recognizing the benefits of tax-return positions in the financial statements as “more-likely-than-not” to be sustained by the taxing authorities. FIN 48 also requires explicit disclosure requirements about a Company’s uncertainties related to their income tax position, including a detailed roll-forward of tax benefits taken that do not qualify for financial statement recognition. The Company adopted FIN 48 effective January 1, 2007, and its adoption did not have a material effect on the Company’s financial position, results of operations or cash flows.

The Company and its wholly-owned domestic subsidiaries are subject to U.S. federal income tax as well as income tax of multiple state jurisdictions. The Company’s wholly-owned subsidiary based in the United Kingdom is subject to income taxes imposed by the United Kingdom.

The Company’s practice is to recognize interest and/or penalties related to income tax matters in income tax expense. To date, such interest and penalty charges have not been material.

A deferred tax asset or liability is recorded for temporary differences in the bases of assets and liabilities for book and tax purposes and loss carry forwards based on enacted rates expected to be in effect when these temporary items are expected to reverse. Valuation allowances are provided to the extent it is more likely than not that all or a portion of the deferred tax assets will not be realized.

At December 31, 2008, the Company had two stock-based employee and director compensation plans and a compensatory employee stock purchase plan, which are described more fully in Note 5.

On January 1, 2006, the Company adopted Statement of Financial Accounting Standards (“SFAS”) No. 123 (revised 2004) (“FAS 123(R)”), “Share-based Payment.” Under FAS 123(R), the Company measures and records the compensation cost of employee and director services received in exchange for stock option grants and other equity awards based on the grant-date fair value of the awards. The values of the portions of the awards that are ultimately expected to vest are recognized as expense over the requisite service periods. The Company accounts for stock options and awards granted to non-employees other than directors using the fair-value method.

The Company adopted FAS 123(R) using the modified prospective method, pursuant to which the Company’s financial statements for prior reporting periods have not been adjusted to include compensation cost calculated under the fair-value method. Prior to 2006, the Company used the intrinsic value method to measure compensation expense associated with the grants of stock options or awards to employees and directors. Under the intrinsic value method, compensation associated with such grants and awards was determined as the excess, if any, of the current fair value of the underlying common stock on the date of grant over the price an employee or director must pay to exercise the award.

The Company’s calculations of the fair value of stock option grants were made using the Black-Scholes option pricing model with the following assumptions, and resulted in the following weighted average grant-date fair values of options granted during the years ended December 31:

The risk-free interest rate is derived quarterly from the published US Treasury yield curve, based on expected term, in effect as of the last several days of the quarter. The Company uses historical volatility of the Company’s common stock to estimate expected volatility. For the years 2006 and 2007, the expected term of

options granted was estimated to be equal to the average of the contractual life of the options and the grant’s average vesting period. For 2008, the expected term of options was derived from Company historical data, including, among other things, option exercises, forfeitures and cancellations.

The following table summarizes the components of stock-based compensation expense for the years ended December 31:

As of December 31, 2008, unamortized compensation cost, net of estimated forfeitures, related to nonvested stock options and nonvested restricted shares granted under the various stock incentive plans, amounted to $1.9 million and $673,000, respectively. These costs are expected to be amortized over weighted average periods of 1.7 years and 0.9 years, respectively.

The financial statements of foreign subsidiaries are translated into U.S. dollars in accordance with SFAS No. 52, “Foreign Currency Translation.” Where the functional currency of a foreign subsidiary is its local currency, balance sheet accounts are translated at the current exchange rate and income statement accounts are translated at the average exchange rate for the period. Gains and losses resulting from translation are accumulated in a separate component of stockholders’ equity. Gains or losses on foreign currency transactions are recognized in current operations in other income, net. For the years ended December 30, 2006, 2007 and 2008, foreign currency transactions gains and losses were not significant.

In February 2007, the FASB issued SFAS No. 159, “The Fair Value Option for Financial Assets and Financial Liabilities” (“SFAS 159”), including an amendment to SFAS No. 115. SFAS 159 provides entities with the irrevocable option to measure eligible financial assets, financial liabilities and firm commitments at fair value, on an instrument-by-instrument basis, that are otherwise not permitted to be accounted for at fair value under other accounting standards. The election, called the fair value option, will enable entities to achieve an offset accounting effect for changes in fair value of certain related assets and liabilities without having to apply complex hedge accounting provisions. The Company has adopted SFAS No. 159 beginning January 1, 2008 and its adoption did not have a material effect on the Company’s financial position or results of operations.

In December 2007, the FASB issued SFAS No. 141 (revised 2007) (“SFAS 141(R)”), “Business Combinations” which replaces SFAS No. 141. SFAS 141(R) applies to all transactions and other events in which one entity obtains control over one or more other businesses, regardless of whether consideration is involved. Under SFAS 141(R), an acquirer will recognize the assets acquired, the liabilities assumed, and any noncontrolling interest in the acquiree at the acquisition date, measured at their fair values as of that date, with limited exceptions. Among its other provisions, SFAS 141(R) mandates that (i) acquisition-related costs, including any post-acquisition restructuring costs that the acquirer expected but was not obligated to incur, generally be expensed when incurred, (ii) contingent consideration be recognized and recorded at fair value at the acquisition date, with subsequent changes in fair value to be recognized in the income statement or as equity adjustments, and (iii) in-process research and development be capitalized as an indefinite-lived intangible asset until project completion, after which time its value would be amortized over the related product’s estimated useful life or expensed if there is no alternative future use. SFAS 141(R) is effective for fiscal years beginning after December 15, 2008.

In December 2007, the FASB issued SFAS No. 160, “Noncontrolling Interests in Consolidated Financial Statements—an amendment of ARB No. 51” (“SFAS 160”). SFAS 160 amends Accounting Research Bulletin No. 51 to establish accounting and reporting standards for the noncontrolling interest in a subsidiary and for the deconsolidation of a subsidiary. This statement clarifies that a noncontrolling interest in a subsidiary is an ownership interest in the consolidated entity that should be measured at fair value and reported as equity in the consolidated financial statements. SFAS 160 requires consolidated net income to be reported at amounts that include the amounts attributable to both the parent and the noncontrolling interest. Also, this Statement requires that a parent recognize a gain or loss in net income when a subsidiary is deconsolidated, in which any remaining noncontrolling equity investment in the former subsidiary is measured at its fair value. SFAS 160 is effective for fiscal years beginning after December 15, 2008. The Company has adopted SFAS 160 as of January 1, 2009 and its adoption had no material effect on the Company’s financial position or results of operations.

In May 2008, the FASB issued FASB Staff Position APB No. 14-1, “Accounting for Convertible Debt Instruments That May Be Settled in Cash upon Conversion (Including Partial Cash Settlement)” (“APB 14-1”), which applies to convertible debt that includes a cash conversion feature. Under APB 14-1, the liability and equity components of convertible debt instruments within the scope of this pronouncement shall be separately accounted for in a manner that will reflect the entity’s nonconvertible debt borrowing rate when interest cost is recognized in subsequent periods. APB 14-1 is effective for fiscal years beginning after December 15, 2008. Because the senior convertible notes issued by the Company (see Note 4 below) do not currently include a cash conversion feature, the Company believes that adoption of APB14-1 will not have a material effect on the Company’s financial position or results of operations.

Beginning in 2007, the Company has revised its presentation of net revenues into three reportable categories: (i) Recurring revenue, which consists of fees generated from the provision of maintenance, support, and hosting services and subscription revenues, (ii) Services revenue, which is comprised of professional service and training fees and reimbursable expenses, and (iii) License revenue, which consists of non-recurring license fees generated from perpetual license agreements. Previously, net revenues were presented as either Product revenues, comprised of license and subscription fees, or Service revenues, comprised of revenues generated from professional services, maintenance and support, and hosting arrangements. Also, in order for its various cost of revenues to be combined and presented in the same manner as its reported revenues, the Company has reclassified certain amounts previously included in Cost of services into the newly-created Cost of recurring revenue. The related amounts for 2006 in the Consolidated Statements of Operations have been reclassified to be consistent with the current year presentation.

Certain other prior year account balances have been reclassified to be consistent with the current year’s presentation.

On February 20, 2008, the Company completed its purchase of the assets related to the ClaimRight data validation software business (“ClaimRight”) from Global Healthcare Exchange LLC and Global HealthCare Exchange, Inc. (collectively “GHX”) for $2.0 million, which consisted of $1.4 million in cash paid upon closing, assumed liabilities of $206,000, transaction costs of $181,000, and an additional $200,000 in cash consideration that was paid in January 2009 based on the realization of certain predefined performance milestones. Effective February 20, 2009, the 12-month term for the accrual of contingent consideration had expired and no additional consideration can be earned by GHX. The ClaimRight business was located in Ambler, Pennsylvania and marketed software to pharmaceutical providers for the processing and validating of pharmaceutical claim submissions. This purchase provides the Company with an established customer base and technology that enhances its product offering to its pharmaceutical manufacturing clients. The Company has consolidated the operations of ClaimRight beginning on the date of acquisition.

The following table summarizes the estimated fair values of the assets acquired and liabilities assumed at the date of acquisition (amounts in thousands):

The $300,000 of acquired intangible assets represents the fair value of the ClaimRight in-force customer relationships, which is being amortized over a four-year life. The entire value of acquired intangible assets, in-process research and development, and goodwill was assigned to the health and life sciences segment.

The portion of the purchase price allocated to in-process research and development, totaling $760,000, was expensed upon consummation of the ClaimRight acquisition. This allocation was attributable to one in-process research and development project, which consisted of the development of significant new features and functionality to an existing software product. The ClaimRight business had achieved significant technological milestones on the project as of the acquisition date, but the project had not reached technological feasibility. The estimated fair value of the acquired in-process research and development for this project was determined using the cost approach, due to the unavailability of reasonable estimates of future material cash flows in connection with this project. The Company was able to estimate the cost involved in recreating the technology using historical data, including cost and effort applied to the development of the technology prior to the acquisition date. Significant appraisal assumptions included historical data related to personnel effort, costs associated with those efforts, and any related external costs.

At the time of the acquisition, the in-process ClaimRight development project was approximately 80% to 90% complete. Subsequent to the acquisition, the Company discontinued work on this project prior to its completion and reassigned personnel to incorporate much of the functionality of this project into one of the Company’s competing software programs.

On May 5, 2008, the Company completed its acquisition of all of the outstanding capital stock of Edge Dynamics, Inc. (“Edge Dynamics”), a privately-held developer of channel- and demand-management software based in Redwood City, California, for a purchase price of $500,000 plus the repayment and assumption of other obligations. The total merger consideration of approximately $5.1 million consisted of $500,000 in cash paid to the shareholders of Edge Dynamics, $1.7 million in cash paid to extinguish Edge Dynamics’ outstanding bank debt, the assumption of Edge Dynamics’ liabilities of $2.9 million, and transaction costs of approximately $290,000, less Edge Dynamics’ cash balance of $231,000.

Edge Dynamics developed and marketed channel- and demand-management software to companies in the pharmaceutical industry. This purchase provides the Company with an established customer base and technology that the Company believes will enhance its product offering to its pharmaceutical manufacturing clients. The Company has consolidated the operations of Edge Dynamics beginning on the date of acquisition.

The following table summarizes the estimated fair values of the assets acquired and liabilities assumed at the date of acquisition (amounts in thousands):

The $2.3 million of acquired intangible assets represents the fair values of the Edge Dynamics technology ($1.5 million) and in-force customer relationships ($800,000), which are each being amortized over a four-year life. The entire value of acquired intangible assets, in-process research and development, and goodwill was assigned to the health and life sciences segment.

The portion of the purchase price allocated to in-process research and development, totaling $800,000, was expensed upon consummation of the Edge Dynamics acquisition. This allocation was attributable to one in-process research and development project, which consisted of the development of significant new features and functionality to an existing software product. Edge Dynamics had achieved significant technological milestones on the project as of the acquisition date, but the project had not reached technological feasibility. The value of the purchased in-process research and development was computed using a discount rate of 30% on the projected incremental revenue stream of the product enhancements, net of anticipated costs and expenses. The 30% discount rate was derived based on the Company’s estimated weighted average cost of capital as adjusted to reflect the additional risk inherent in product development and the stage of development. The discounted cash flows were based on management’s forecast of future revenue, costs of revenue and operating expenses related to the products and technologies acquired from Edge Dynamics. The determined value was then adjusted to reflect only the value creation efforts of Edge Dynamics prior to the close of the acquisition. At the time of the acquisition, the project was approximately 75% complete. As of September 30, 2008, the Company had invested approximately $550,000 in the project following acquisition. The project’s development progressed, in all material respects, consistently with the assumptions that the Company had used for estimating its fair value and was completed in September 2008.

The following unaudited pro forma information summarizes the effect of the ClaimRight and Edge Dynamics acquisitions, as if the acquisitions had occurred as of January 1, 2007. This pro forma information is presented for informational purposes only. It is based on historical information and does not purport to represent the actual results that may have occurred had the Company consummated the acquisition on January 1, 2007, nor is it necessarily indicative of future results of operations of the combined enterprises. Pro forma results are in thousands of dollars, except per share data:

The cost and accumulated depreciation of property and equipment consist of the following at December 31:

Depreciation expense was $824,000, and $891,000 and $1.2 million, respectively, for the years ended December 31, 2006, 2007 and 2008.

The gross carrying value and accumulated amortization of other acquired intangible assets consist of the following:

Amortization expense for acquired technology and customer lists was $482,000, $185,000 and $471,000, respectively, for the years ended December 31, 2006, 2007 and 2008.

Acquired intangible assets are being amortized on a straight-line basis over a four-year life. Projected future annual amortization is as follows for the years ended December 31 (in thousands):

On December 31, 2007, the Company completed a private placement of $17.0 million of senior convertible notes (“Notes”). The Notes bear interest at 6.5% per annum, payable quarterly in arrears, and will mature on December 31, 2012. The Notes are convertible into shares of the Company’s common stock at a conversion price of $3.8192 per share, subject to adjustment in the event of a merger or other change in control of the Company. Also, the Notes can be redeemed at par by the investors on December 31, 2010, or redeemed at par by the Company any time beginning on December 31, 2010. Net proceeds to the Company were approximately $15.8 million, after deducting commissions and other fees. The $1.2 million in debt issuance costs is being amortized into interest expense using the effective interest method over the three-year period leading up to the date at which the Notes are first redeemable by the investors. In connection with the Notes, the Company incurred interest expense of $1.5 million during the year ended December 31, 2008, such amount including debt issuance cost amortization of $367,000. As discussed more fully below, the Notes would be in default, and the holders of the Notes could require the Company to redeem the Notes for their principal amount and accrued interest, if the Company’s common stock is delisted from the NASDAQ Capital Market.

The Notes were issued in reliance upon exemptions from the registration provisions of Section 4(2) of the Securities Act of 1933 as amended, and Regulation D thereunder. The shares of common stock issuable upon conversion of the Notes have been registered with the Securities and Exchange Commission and the registration became effective as of February 27, 2008.

Until all of the Notes have been converted, redeemed or otherwise satisfied in accordance with their terms, the Company is prohibited from redeeming or repurchasing any of its capital stock (except in connection with forfeitures of unvested restricted stock), or declaring or paying any cash dividend without the prior express written consent of the holders of Notes representing at least a majority of the aggregate principal amount of the Notes then outstanding.

On October 21, 2008, the Company received notice from The NASDAQ Stock Market LLC (“NASDAQ”) that the market value of its listed securities had been below the minimum $35 million for the previous ten consecutive business days, and that if the market value of the Company’s listed securities did not exceed $35 million for a minimum of ten consecutive business days at any time prior to November 20, 2008, the Company’s common stock would be subject to delisting unless the Company were to request a hearing before a NASDAQ Listing Qualifications Panel. We requested a hearing and, on January 8, 2009, presented our plan to the Panel for regaining compliance with all applicable requirements for continued listing. On March 20, 2009, the Company received notification from the Panel that it had determined to grant the Company’s request to remain listed on the NASDAQ Capital Market, subject to the condition that, among other things, the Company evidence stockholders’ equity at or above $2.5 million on or before May 26, 2009. The Panel reserves the right to reconsider the terms of this exception under circumstances that make continued listing of the Company’s common stock on the NASDAQ Capital Market unwarranted. While the Company is working to regain compliance, there can be no assurance that the Company will be able to regain compliance by the deadline established by the Panel.

The delisting of the Company’s common stock from the NASDAQ Capital Market is an event of default under the Company’s Notes. In the event of such a default, the holders of the Notes would be entitled to declare the entire principal amount and interest due and payable immediately. The Company currently does not have sufficient cash and short-term investments to repay the full principal amount of the Notes. The Company intends to seek a waiver of this default from the holders of the Notes; however, there can be no assurance that it will be able to obtain a waiver on favorable terms, if at all. If the Company is unable to obtain a waiver, it would be unable to repay the Notes without raising additional capital and its ability to continue as a going concern would be in significant doubt.

The Company has authorized capital stock of 105,000,000 shares, of which 100,000,000 shares are designated as common stock, $0.0001 par value per share, and 5,000,000 shares are designated for preferred stock, $0.01 par value per share. At December 31, 2007 and 2008, the Company had reserved 15,800,330 and 15,429,726 shares of common stock, respectively, for issuance upon the exercise of stock options and warrants and the conversion of convertible notes payable.

On November 6, 2006, the Company completed a private placement of its securities, issuing 3,535,566 shares of its common stock and common stock purchase warrants to purchase up to an additional 1,060,663 shares of common stock. The per unit price of the private placement offering was $1.98, with each unit comprised of one share of common stock and a warrant to purchase three-tenths of a share of common stock. The warrants are exercisable at $2.11 per share until November 2011. Net proceeds to the Company were approximately $6.5 million, after deducting commissions and other fees. These shares of common stock and those issuable upon exercise of the warrants have been registered with the Securities and Exchange Commission and the registration became effective as of February 5, 2007.

In July 2007, the Company retired all 1,700 designated shares of its Series A Convertible Preferred Stock, which had been originally designated by the Company in February 2002. No such shares had been outstanding since July 2002.

In March 2000, the Company adopted the 2000 Non-Employee Director Stock Option Plan (“Director Plan”), which provided for the grant of up to 562,500 shares of common stock in the form of nonqualified stock options to directors who are not employees. Each non-employee director was eligible to be granted an option to purchase 62,500 shares of common stock upon initial election or appointment to the board. In addition, each non-employee director was entitled to receive an option to purchase 25,000 shares of common stock on the date of each annual meeting of stockholders. In 2008, the Board of Directors terminated the Director Plan in conjunction with the Stockholders’ approval of the 2008 Stock Incentive Plan (“2008 Plan”).

In April 2001, the Company adopted the 2001 Employee Stock Option Plan, which provides for the grant of up to 1,000,000 shares of common stock in the form of nonqualified stock options. All of the Company’s officers, employees, directors, consultants and advisors are eligible to receive awards under the 2001 Employee Stock Option Plan, with not more than 25,000 shares to be issued in the aggregate to officers or directors of the Company. This plan is administered by the Company’s Board of Directors and its Executive Compensation Committee, which determines the terms of all grants thereunder.

In June 2001, the Company adopted the 2001 Stock Incentive Plan, which provided for the grant of up to 5,000,000 shares of common stock in the form of incentive stock options, nonqualified stock options, restricted stock awards and other stock-based awards. In addition, if any previous award under the 2001 Stock Incentive Plan or other previously-adopted option plans of the Company expired or was terminated, surrendered or cancelled without having been fully exercised, the unissued shares covered by any such award were available for grant under the 2001 Stock Incentive Plan. All of the Company’s officers, employees, directors, consultants and advisors were eligible to receive awards under the 2001 Stock Incentive Plan. In 2008, the Board of Directors terminated the 2001 Stock Incentive Plan in conjunction with the stockholders’ approval of the 2008 Plan.

In June 2003, the Company adopted the 2003 Stock Incentive Plan (“2003 Plan”), which provided for the grant of up to 5,000,000 shares of common stock in the form of incentive stock options, nonqualified stock

options, restricted stock awards and other stock-based awards. All of the Company’s officers, employees, directors, consultants and advisors were eligible to receive awards under the 2003 Plan. In 2008, the Board of Directors terminated the 2003 Plan in conjunction with the Stockholders’ approval of the 2008 Plan.

In May 2008, the Company adopted the 2008 Plan, which provides for the grant of up to 1,000,000 shares of common stock in the form of incentive stock options, nonqualified stock options, restricted stock awards and other stock-based awards. In addition, if any previous award under the 2003 Plan or other previously-adopted option plans of the Company expires or is terminated, surrendered or cancelled without having been fully exercised, the unissued shares covered by any such award are available for grant under the 2008 Plan. Also, option grants to directors previously issued under the Director Plan will now be issued under the 2008 Plan. All of the Company’s officers, employees, directors, consultants and advisors are eligible to receive awards under the 2008 Plan.

Stock options terminate 10 years after grant and vest over periods set by the Compensation Committee of the Board of Directors at the time of grant. These vesting periods have generally been for four years, on a ratable basis. Certain stock option awards provide for accelerated vesting if there is a change in control of the Company. Beginning in 2006, the Compensation Committee of the Board of Directors has also granted stock options to senior executives of the Company that vest on the earlier of five years after grant or the date that specified operational milestones are attained. For the years ended December 31, 2007 and 2008, the Company recognized $262,000 and $170,000, respectively, of accelerated stock-based compensation expense in connection with the attainment of such milestones.

The following table summarizes total common shares available for future grants of stock options and other equity awards at December 31, 2008:

The following table summarizes stock option activity under all of the Company’s stock option plans for the years ended December 31, 2006, 2007 and 2008:

The total intrinsic value of stock options exercised during the years ended December 31, 2006, 2007 and 2008 was $1.1 million, $854,000 and $81,000, respectively.

A summary of the status of the Company’s nonvested restricted shares as of December 31, 2008, and changes during the years ended December 31, 2006, 2007 and 2008, is presented below:

The total fair value of restricted shares which vested during the years ended December 31, 2006, 2007 and 2008 was $319,000, $373,000 and $166,000, respectively.

In March 2000, the Company adopted the 2000 Employee Stock Purchase Plan (ESPP), which authorizes the issuance of up to 1,250,000 shares of common stock to participating employees at 85% of the closing price of the common stock on the first day or last day of each offering period, whichever is lower. Because of the presence of option and discount features, the Company’s ESPP is treated for accounting purposes as a compensatory plan in accordance with FAS 123(R). For plan periods following December 2008, the ESPP was suspended due to the shortage of authorized shares available for grant relative to the likely number of shares to be issued at the next issuance date if the plan was still active.

As of December 31, 2008, a total of 52,904 shares were available for grant under the Company’s ESPP. The following table summarizes the number of shares and per share prices for purchases since January 1, 2006:

At December 31, 2007 and 2008, the Company had warrants outstanding at exercise prices ranging from $1.20 to $13.20, as described below.

In August 2001, as part of a merger transaction, the Company issued a warrant to purchase 4,546 shares of the Company’s stock at an exercise price of $13.20. This warrant expires in November 2010.

In February 2002, the Company granted two warrants to common stock investors pursuant to a private placement offering, one of which expired during 2002. The remaining warrant to purchase 165,062 shares of the Company’s common stock, which was exercisable for a period of seven years at an exercise price of $7.50 per share, expired in February 2009.

In November 2006, the Company granted warrants to common stock investors pursuant to a private placement offering. The warrants to purchase up to 1,060,663 shares of the Company’s common stock, of which 8,083 shares were exercised in 2008, are exercisable for a period of five years at an exercise price of $2.11 per share.

A summary of the Company’s outstanding warrants as of December 31, 2008 is presented below:

There was no provision for income taxes recorded or income taxes paid in the years ended December 31, 2006, 2007 and 2008. At December 31, 2008, the Company had approximately $156 million of U.S. federal net operating loss carryforwards and research and development credit carryforwards of $5.5 million. The federal net operating loss carryforwards expire in the years 2019 through 2028 and are subject to certain annual limitations. The federal research and development credit carryforwards expire in the years 2008 through 2028. Due to the uncertainty surrounding the Company’s ability to realize these net operating loss carryforwards, tax credits and its other deferred tax assets, a full valuation allowance has been placed against the otherwise recognizable net deferred tax asset.

The Company adopted FIN 48 effective January 1, 2007. The Company did not have a liability related to unrecognized tax benefits as of January 1, 2008 and December 31, 2008 but has reduced its deferred tax assets by $1.3 million and $1.4 million, respectively, in connection therewith. However, because the Company has recorded a full valuation allowance on its net deferred tax assets, the effect of implementing FIN 48 has been a reduction of such allowance by the respective amounts above.

The total amount of unrecognized tax benefits as of December 31, 2008 was approximately $1.4 million, all of which would affect the effective tax rate if recognized. The amount of unrecognized tax benefits that will change in the next 12 months is not significant and we do not expect the change to have a material impact on our consolidated financial statements.

The following table discloses the reconciliation of the beginning and ending balances of unrecognized tax benefits:

The Company did not incur any interest and penalties. As indicated as of the date of adoption of FIN 48, the Company has elected to classify interest and penalties as a component of the provision for income taxes.

At December 31, 2008 there were approximately $156 million of federal net operating loss carryovers. In addition, the Company has approximately $145 million of state and $3 million of foreign (UK) net operating loss carryovers. The state net operating losses will begin expiring in 2009 through 2028 and the foreign (UK) net operating losses can be carried forward indefinitely. The Company has not conducted a formal IRC Section 382 study, however it is likely that there has been a significant ownership change and some of the NOL’s may be limited. The above NOL does not include approximately $22.7 million of NOL’s from the acquisition of Edge Dynamics. Due to IRC Section 382 limitations, the Company will be able to use approximately $240,000 of this NOL going forward per year for a total of about $5 million. The Company has not recorded a deferred tax asset for the $22.7 million that will not be utilized due to IRC Section 382 limitations.

The tax years subject to examination by major tax jurisdictions include the years 2005 and forward by the U.S. Internal Revenue Service, the years 2004 and forward for certain states and the years 2008 and forward for the United Kingdom.

A reconciliation of the U.S. federal statutory rate to the effective rate is as follows:

Under the terms of certain of the Company’s merger agreements, the Company has agreed to not take any action that could violate the tax-free merger status of these mergers. In the event that tax authorities determine that a merger no longer qualifies as a tax-free exchange, the Company may be required to reimburse the selling party to the merger for any additional taxes that may be imposed on the selling party. In such a circumstance, the Company would receive additional tax basis in the assets acquired in the merger.

The Company leases its facilities under non-cancelable operating lease agreements and certain of its equipment under non-cancelable capital and operating lease agreements through 2011. Future minimum lease commitments under all non-cancelable leases at December 31, 2008 are approximately as follows:

At December 31, 2008, future minimum lease commitments included an aggregate of $2.2 million related to leased office space that is no longer in productive use. The net present value of this $2.2 million aggregate lease commitment, as offset by future estimated sublease receipts totaling $1.4 million, is included in other long-term liabilities and accrued expenses as indicated in Note 12.

Included in property and equipment are assets acquired pursuant to capital lease arrangements as follows at December 31:

Total rent expense was approximately $1.2 million, $1.3 million and $1.4 million for the years ended December 31, 2006, 2007 and 2008, respectively.

The Company is often involved in contractual disputes, litigation and potential claims arising in the ordinary course of business. The Company does not believe that the resolution of any such matters which are pending will have a material adverse effect on the Company’s financial position or results of operations. The Company is not a party to any material pending legal proceedings.

The Company measures operating results as two reportable segments, each of which provide multiple products and services that allow manufacturers, purchasers and intermediaries to manage their complex contracts for the purchase and sale of goods. These segments are consistent with how management establishes strategic goals, allocates resources and evaluates performance. The accounting policies of the segments are the same as those described in the summary of significant accounting policies. The Company’s reportable segments are strategic business units that market to separate and distinct industry groups: (i) health and life sciences, which includes pharmaceutical manufacturers, and (ii) industry solutions, which comprises all other industries. The following tables reflect the results of the segments consistent with the Company’s management system.

For segment reporting purposes, unallocated amounts consist of goodwill and acquired intangible asset values and related amortization amounts with respect to the 2002 acquisition of Menerva Technologies, Inc. Interest income, interest expense, income tax expense or benefit, and unusual items that are attributable to the segments do not have a significant effect on the financial results of the segments. In performing the annual goodwill impairment test, goodwill is assigned to the Company’s reportable segments.

The Company sponsors a 401(k) defined contribution plan as a retirement plan for its qualifying employees. In April 2006, the Company began to provide a discretionary matching contribution. The matching contributions paid by the Company during the years ended December, 31, 2006, 2007 and 2008 amounted to $111,000, $199,000 and $228,000, respectively.

In December 2008, the Company implemented a significant restructuring of its operations in order to streamline operations and better align operating expenses levels with a conservative revenue forecast for 2009. As part of this downsizing, the Company eliminated 49 employee positions, moved its London office to a smaller facility, and incurred $641,000 in severance charges and $216,000 in lease loss costs. The net result of the workforce restructuring was a reduction in the Company’s headcount from 209 at November 30, 2008 to 164 at January 31, 2009. With respect to the London office move, the Company determined the fair value of the remaining liability (net of estimated sublease rentals) on its London office lease as of December 31, 2008.

In 2003 and 2004, the Company took several actions to reduce its operating expenses in order to better align its cost structure with projected revenues and to streamline its operations in advance of a planned (and subsequently terminated) sale of its health and life sciences operation. These actions included the closing of its office in Chicago, Illinois and the partial closing of its facility in London, England. With respect to the Chicago and London office closings, the Company had determined the fair value of the remaining liabilities of the unused space (net of estimated sublease rentals) for each lease as of the respective cease-use dates. For the years ended December 31, 2006, 2007 and 2008, the Company incurred charges of $103,000, $93,000 and $43,000, respectively, in connection with the amortization of its long-term lease restructuring accruals in connection with the 2003 and 2004 downsizings.

A rollforward of the Company’s accrued liability for restructuring and other charges is as follows:

(a) Evaluation of Disclosure Controls and Procedures. Under the supervision and with the participation of management, including our principal executive officer and principal financial officer, we evaluated the effectiveness of the design and operation of our disclosure controls and procedures as of the end of the period covered by this annual report as such term is defined in Rules 13a-15(e) promulgated under the Securities Exchange Act of 1934, as amended (the “Exchange Act”). Based on this evaluation, our management, including our principal executive officer and principal financial officer, concluded that our disclosure controls and procedures were effective as of December 31, 2008 to ensure that all material information required to be disclosed by us in reports that we file or submit under the Exchange Act is accumulated and communicated to them as appropriate to allow timely decisions regarding required disclosure and that all such information is recorded, processed, summarized and reported within the time periods specified in the SEC’s rules and forms.

(b) Management’s Assessment of the Effectiveness of Internal Control Over Financial Reporting. Our management, under the supervision of our Chief Executive Officer and Chief Financial Officer, is responsible for establishing and maintaining an adequate system of internal control over financial reporting. Internal control over

financial reporting is a process designed to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external reporting purposes in accordance with accounting principles generally accepted in the United States. Because of its inherent limitations, internal control over financial reporting may not prevent or detect misstatements. Therefore, even those systems determined to be effective can only provide reasonable assurance with respect to financial statement preparation and presentation. The Company’s management assessed the effectiveness of the Company’s internal control over financial reporting as of December 31, 2008. In making this assessment, the Company’s management used the criteria set forth by the Committee of Sponsoring Organizations of the Treadway Commission (COSO) in Internal Control-Integrated Framework. Based on our assessment, management believes that, as of December 31, 2008, the Company’s internal control over financial reporting is effective based on those criteria.

(c) Changes in Internal Control. No change in our internal control over financial reporting occurred during the quarter ended December 31, 2008 that has materially affected, or is reasonably likely to materially affect, our internal control over financial reporting.

See the information set forth in the sections entitled “Election of Directors” and “Corporate Governance” and in the subsections entitled “Certain Relationships and Related Transactions” and “Section 16(a) Beneficial Ownership Reporting Compliance” in our Proxy Statement for the 2009 Annual Meeting of Stockholders to be filed with the SEC within 120 days after the end of our fiscal year ended December 31, 2008, which we refer to as the “2009 Proxy Statement,” which is incorporated herein by reference, and the information set forth in the section entitled “Executive Officers of the Registrant” in Part I, Item 4A of this Annual Report on Form 10-K.

See the information set forth in the section entitled “Executive and Director Compensation” in the 2009 Proxy Statement, which is incorporated herein by reference.

See the information set forth in the section entitled “Stock Ownership of Certain Beneficial Owners and Management” in the 2009 Proxy Statement, which is incorporated herein by reference.

The following table provides information as of December 31, 2008 about our common stock that may be issued to employees, consultants or members of the Board of Directors under all of our existing equity compensation plans.

See the information set forth in the sections entitled “Director Nominees” and “Certain Relationships and Related Transactions” in the 2009 Proxy Statement, which is incorporated herein by reference.

See the information set forth in the section entitled “Audit Fees and Other Matters” in the 2009 Proxy Statement, which is incorporated herein by reference.

The consolidated financial statements listed below together with the report thereon of BDO Seidman, LLP, the Company’s independent registered public accounting firm, dated March 30, 2009 are included in this report in Item 8 and are incorporated herein by reference.

Consolidated Statements of Operations for the years ended December 31, 2006, 2007 and 2008

Consolidated Statements of Stockholders’ Equity for the years ended December 31, 2006, 2007 and 2008

Consolidated Statements of Cash Flows for the years ended December 31, 2006, 2007 and 2008

The information called for by this paragraph is contained in the Exhibit Index of this report which is incorporated herein by reference.

Pursuant to the requirements of Section 13 or 15(d) of the Securities and Exchange Act of 1934, the Registrant has duly caused this Form 10-K to be signed on its behalf by the undersigned thereunto duly authorized.


I-MANY, INC.

By:		/s/ JOHN A. RADE
		John A. Rade
		Chief Executive Officer, Chairman of the Board of Directors and President

Date: March 30, 2009

		/s/ KEVIN M. HARRIS
		Kevin M. Harris Chief Financial Officer and Treasurer

Date: March 30, 2009

KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below constitutes and appoints John A. Rade and Kevin M. Harris, jointly and severally, his attorney-in-fact, each with the power of substitution, for him in any and all capacities, to sign any amendments to this Report on Form 10-K and to file same, with exhibits thereto and other documents in connection therewith, with the Securities and Exchange Commission, hereby ratifying and confirming all that each of said attorney-in-fact, or his substitute or substitutes, may do or cause to be done by virtue hereof.

Pursuant to the requirements of the Securities Exchange Act of 1934, this Form 10-K has been signed below by the following persons on behalf of the Registrant and in the capacities and on the dates indicated.


DELAWARE		01-0524931
(State or other jurisdiction of incorporation or organization)		(IRS Employer Identification Number)

399 Thornall Street 12th Floor Edison, New Jersey		08837
(Address of principal executive offices)		(Zip Code)


Title of Each Class:		Name of Each Exchange on which Registered:
Common Stock, $0.0001 par value per share		NASDAQ Capital Market


Three Months Ended	Price Range of Common Stock
Three Months Ended	High		Low
December 31, 2008	$	0.72	$	0.13
September 30, 2008		1.00		0.63
June 30, 2008		2.52		1.00
March 31, 2008		3.17		2.23
December 31, 2007		3.34		2.81
September 30, 2007		2.88		2.30
June 30, 2007		2.75		1.71
March 31, 2007		1.99		1.64


	12/2003	12/2004	12/2005	12/2006	12/2007	12/2008
I-many, Inc.	100.00	150.00	140.00	165.00	310.00	22.00
NASDAQ Composite	100.00	110.08	112.88	126.51	138.13	80.47
Morgan Stanley High Technology	100.00	106.43	108.59	120.54	149.02	85.05


	YEAR ENDED DECEMBER 31,
	2004			2005			2006			2007			2008
	(IN THOUSANDS, EXCEPT PER SHARE DATA)
STATEMENT OF OPERATIONS DATA:
Total net revenues	$	38,413		$	32,576		$	29,575		$	40,552		$	34,397
Net loss		(7,290	)		(9,305	)		(15,815	)		(9,808	)		(15,556	)
Net loss per share		(0.18	)		(0.21	)		(0.33	)		(0.19	)		(0.30	)

	AS OF DECEMBER 31,
	2004			2005			2006			2007			2008
	(IN THOUSANDS)
BALANCE SHEET DATA:
Cash and cash equivalents	$	6,098		$	16,805		$	17,232		$	28,588		$	9,342
Short-term investments and available for sale Securities		14,610			—			—			—			—
Working capital		14,645			9,407			3,047			12,432			(5,415	)
Total assets		44,198			38,472			36,985			47,667			31,227
Capital lease obligations, including current portion		160			21			394			573			611
Long-term debt obligations		—			—			—			17,000			17,000
Total stockholders’ equity (deficit)		25,870			18,356			11,454			4,623			(8,705	)


ITEM		PAGE NO.
	PART I

1.	Business	3
1A.	Risk Factors	11
1B.	Unresolved Staff Comments	14
2.	Properties	14
3.	Legal Proceedings	14
4.	Submission of Matters to a Vote of Security Holders	14
4A.	Executive Officers of the Registrant	14

	PART II

5.	Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities	17
6.	Selected Consolidated Financial Data	19
7.	Management’s Discussion and Analysis of Financial Condition and Results of Operations	19
7A.	Quantitative and Qualitative Disclosures About Market Risk	35
8.	Financial Statements and Supplementary Data	37
9.	Changes in and Disagreements with Accountants on Accounting and Financial Disclosure	65
9A.	Controls and Procedures	65
9B.	Other Information	66

	PART III

10.	Directors, Executive Officers and Corporate Governance	67
11.	Executive Compensation	67
12.	Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters	67
13.	Certain Relationships and Related Transactions, and Director Independence	67
14.	Principal Accountant Fees and Services	67

	PART IV

15.	Exhibits, Financial Statement Schedules	68

SIGNATURES		71


	Three months ended December 31,				Twelve months ended December 31,
	2007		2008		2007		2008
	(AMOUNTS IN THOUSANDS)
Gross value of license contracts sold:
Health and Life Sciences	$	3,586	$	1,390	$	15,543	$	4,042
Industry Solutions		644		122		1,377		362

		4,230		1,512		16,920		4,404
Add license revenue recorded in current period from contracts sold in prior periods:
Health and Life Sciences		767		175		1,824		2,447
Industry Solutions		142		61		861		61

		909		236		2,685		2,508
Less value of license contracts sold in current period and not currently recognizable:
Health and Life Sciences		2,396		1,255		11,334		3,403
Industry Solutions		641		95		930		219

		3,037		1,350		12,264		3,622

License revenue recorded:
Health and Life Sciences		1,957		310		6,033		3,086
Industry Solutions		145		88		1,308		204

	$	2,102	$	398	$	7,341	$	3,290


	Payments due by Period—Amounts in $000s
	Total		Less than 1 year		1-3 years		3-5 years		More than 5 years
Long-term Debt Obligations	$	21,696	$	1,381	$	2,210	$	18,105	$	—
Capital Lease Obligations		658		456		202		—		—
Operating Lease Obligations		4,057		1,798		2,259		—		—

Total Contractual Obligations	$	26,411	$	3,635	$	4,671	$	18,105	$	—


		Page
I-MANY, INC.

Reports of Independent Registered Public Accounting Firm		38

Consolidated Balance Sheets as of December 31, 2007 and 2008		40

Consolidated Statements of Operations for the years ended December 31, 2006, 2007 and 2008		41

Consolidated Statements of Stockholders’ Equity (Deficit) for the years ended December 31, 2006, 2007 and 2008		42

Consolidated Statements of Cash Flows for the years ended December 31, 2006, 2007 and 2008		43

Notes to Consolidated Financial Statements		44


	December 31,
	2007			2008
ASSETS
Current assets:
Cash and cash equivalents	$	28,588		$	9,342
Restricted cash		80			80
Accounts receivable, net of allowances of $127 and $107 in 2007 and 2008, respectively		6,606			6,092
Prepaid expenses and other current assets		526			500

Total current assets		35,800			16,014
Property and equipment, net		1,494			1,964
Restricted cash		351			199
Deferred charges and other assets		1,309			1,053
Acquired intangible assets, net		46			2,175
Goodwill		8,667			9,822

Total assets	$	47,667		$	31,227

LIABILITIES AND STOCKHOLDERS’ EQUITY (DEFICIT)
Current liabilities:
Accounts payable	$	2,455		$	1,876
Accrued expenses		6,983			4,714
Current portion of deferred revenue		13,654			14,421
Current portion of capital lease obligations		276			418

Total current liabilities		23,368			21,429
Convertible notes payable		17,000			17,000
Deferred revenue, net of current portion		1,664			757
Capital lease obligations, net of current portion		297			193
Other long-term liabilities		715			553

Total liabilities		43,044			39,932

Commitments and contingencies (Note 7)
Stockholders’ equity (deficit):
Preferred stock, $.01 par value
Authorized—5,000,000 shares
Issued and outstanding—none		—			—
Common stock, $.0001 par value
Authorized—100,000,000 shares
Issued and outstanding – 52,389,284 and 53,759,888 shares in 2007 and 2008, respectively		5			5
Additional paid-in capital		164,685			166,919
Accumulated other comprehensive loss		(24	)		(30	)
Accumulated deficit		(160,043	)		(175,599	)

Total stockholders’ equity (deficit)		4,623			(8,705	)

Total liabilities and stockholders’ equity (deficit)	$	47,667		$	31,227



Cost of recurring revenue	$	133	$	196	$	140
Cost of services		225		336		386
Sales and marketing		190		337		371
Research and development		300		564		464
General and administrative		635		1,001		635


	Common Stock				Additional Paid-In Capital		Accumulated Other Comprehensive Income (Loss)			Accumulated Deficit			Total Stockholders’ Equity(Deficit)
	Shares		$.0001 Par Value		Additional Paid-In Capital		Accumulated Other Comprehensive Income (Loss)			Accumulated Deficit			Total Stockholders’ Equity(Deficit)
Balance, January 1, 2006	46,823,585		$	5	$	152,767	$	4		$	(134,420	)	$	18,356
Exercise of stock options	812,071			—		456		—			—			456
Exercise of common stock warrant	250,000			—		300		—			—			300
Private placement sale of common stock, net of issuance costs of $477	3,535,566			—		6,523		—			—			6,523
Issuance of restricted common stock	252,860			—		—		—			—			—
Stock-based compensation expense	—			—		1,483		—			—			1,483
Reduction in deferred stock-based compensation resulting from attrition	(72,972	)		—		—		—			—			—
Issuance of common stock pursuant to Employee Stock Purchase Plan	117,882			—		161		—			—			161
Foreign currency translation adjustment	—			—		—		(10	)		—			(10	)
Net loss	—			—		—		—			(15,815	)		(15,815	)

Balance, December 31, 2006	51,718,992			5		161,690		(6	)		(150,235	)		11,454
Exercise of stock options	525,496			—		416		—			—			416
Issuance of restricted common stock	81,132			—		—		—			—			—
Stock-based compensation expense	—			—		2,434		—			—			2,434
Reduction in deferred stock-based compensation resulting from attrition	(20,650	)		—		—		—			—			—
Issuance of common stock pursuant to Employee Stock Purchase Plan	84,314			—		145		—			—			145
Foreign currency translation adjustment	—			—		—		(18	)		—			(18	)
Net loss	—			—		—		—			(9,808	)		(9,808	)

Balance, December 31, 2007	52,389,284			5		164,685		(24	)		(160,043	)		4,623
Exercise of stock options	110,177			—		94		—			—			94
Exercise of common stock warrants	8,083			—		17		—			—			17
Issuance of restricted common stock	1,025,837			—		—		—			—			—
Stock-based compensation expense	—			—		1,996		—			—			1,996
Reduction in deferred stock-based compensation resulting from attrition	(224,220	)		—		—		—			—			—
Issuance of common stock pursuant to Employee Stock Purchase Plan	450,727			—		127		—			—			127
Foreign currency translation adjustment	—			—		—		(6	)		—			(6	)
Net loss	—			—		—		—			(15,556	)		(15,556	)

Balance, December 31, 2008	53,759,888		$	5	$	166,919	$	(30	)	$	(175,599	)	$	(8,705	)


Description		Estimated Useful Lives
Computer software		3 years
Computer hardware		3 years
Furniture and equipment		5-7 years
Leasehold improvements		5 years *


Level 1:		Observable inputs such as quoted prices for identical assets or liabilities in active markets.

Level 2:		Observable inputs other than quoted prices that are directly or indirectly observable for the asset or liability, including quoted prices for similar assets or liabilities in active markets; quoted prices for similar or identical assets or liabilities in markets that are not active; and model-derived valuations whose inputs are observable or whose significant value drivers are observable.

Level 3:		Unobservable inputs that reflect the reporting entity’s own assumptions.


Acquired intangible assets	$	300
Equipment and notes receivable		113
In-process research and development		760
Goodwill		849

Total assets acquired		2,022
Less:
Deferred revenue		(189	)
Other current liabilities		(17	)

Net assets acquired	$	1,816


Acquired intangible assets	$	2,300
Accounts receivable		1,223
Other current assets		78
Equipment and other noncurrent assets		440
In-process research and development		800
Goodwill		306

Total assets acquired		5,147
Less:
Accrued expenses		(1,892	)
Deferred revenue		(776	)
Other current liabilities		(192	)

Net assets acquired	$	2,287


	Year ended December 31,
(Unaudited)	2007			2008
Pro forma revenues	$	49,823		$	36,696
Pro forma net loss		(16,466	)		(18,565	)
Pro forma net loss per share		(0.32	)		(0.35	)


	December 31, 2007				December 31, 2008
	Gross Carrying Amount		Accumulated Amortization		Gross Carrying Amount		Accumulated Amortization
	(Amounts in thousands)
Acquired technology	$	6,043	$	5,997	$	7,543	$	6,277
Customer lists		—		—		1,100		191

Totals	$	6,043	$	5,997	$	8,643	$	6,468


2001 Employee Stock Option Plan		774,780
2008 Stock Incentive Plan		1,498,369

Total available for future grant		2,273,149


	Number of Shares		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term	Aggregate Intrinsic Value ($000)
Outstanding at January 1, 2006	5,655,090		$	1.867
Granted during 2006	3,463,100			1.931
Exercised during 2006	(812,071	)		0.562
Canceled during 2006	(1,129,362	)		2.153

Outstanding at December 31, 2006	7,176,757			2.002
Granted during 2007	1,844,175			2.047
Exercised during 2007	(525,496	)		0.793
Canceled during 2007	(674,134	)		1.908

Outstanding at December 31, 2007	7,821,302			2.102
Granted during 2008	1,468,088			2.108
Exercised during 2008	(110,177	)		0.848
Canceled during 2008	(1,748,928	)		2.151

Outstanding at December 31, 2008	7,430,285		$	2.111	6.9 years	$	-0-

Exercisable at December 31, 2008	4,625,493		$	2.190	6.0 years	$	-0-


	Number of Shares		Weighted Average Grant-Date Fair Value
Nonvested at January 1, 2006	352,036		$	1.480
Granted during 2006	252,860			1.737
Vested during 2006	(199,154	)		1.604
Forfeited during 2006	(72,972	)		1.568

Nonvested at December 31, 2006	332,770			1.582
Granted during 2007	81,132			1.749
Vested during 2007	(239,392	)		1.557
Forfeited during 2007	(20,650	)		1.792

Nonvested at December 31, 2007	153,860			1.682
Granted during 2008	1,025,837			1.069
Vested during 2008	(98,208	)		1.689
Forfeited during 2008	(224,220	)		1.218

Nonvested at December 31, 2008	857,269		$	1.069


	Number of Shares	Price per Share
June 2006	65,131	$	1.165
December 2006	52,751		1.607
June 2007	41,209		1.598
December 2007	43,105		1.836
June 2008	91,363		0.859
December 2008	359,364		0.136


Expiration Date	Number of Shares	Exercise Price Per Share
February 2009	165,062	$	7.50
November 2010	4,546		13.20
November 2011	1,052,580		2.11

Total shares	1,222,188


	(Amounts in thousands)
Balance at January 1, 2008	$	1,287
Gross additions based on tax positions related to current year		92
Reductions in 2008 for tax positions that have expired		(10	)

Balance at December 31, 2007	$	1,369


	Years Ended December 31,
	2006		2007		2008
Federal statutory rate	(34.0	)%	(34.0	)%	(34.0	)%
Research and development tax credits	(2.2	)	(4.4	)	(1.9	)
Amortization of acquired intangible assets	0.4		(0.4	)	—
Write-off of in-process research and development	0.0		0.0		3.6
Impairment write-offs	62.2		—		(34.3	)
Stock option and warrant charges	0.1		3.6		3.9
Other	(4.7	)	2.0		0.3
Valuation allowance for deferred tax asset	(21.8	)	33.2		62.4

Provision (Benefit) for income taxes	—	%	—	%	—	%


	Operating Leases		Capital Leases
	(Amounts in thousands)
Year ending December 31,
2009	$	1,798	$	456
2010		1,423		177
2011		836		25

Total minimum lease payments	$	4,057		658

Less—Amount representing interest				(47	)

Present value of minimum lease payments				611
Less—Current portion of capital lease obligations				(418	)

Capital lease obligations, net of current portion			$	193


	THREE MONTHS ENDED
	MARCH 31, 2007			JUNE 30, 2007			SEPT. 30, 2007			DEC. 31, 2007			MARCH 31, 2008			JUNE 30, 2008			SEPT. 30, 2008			DEC. 31, 2008
	(IN THOUSANDS, EXCEPT PER SHARE DATA)
Total net revenues	$	8,353		$	10,015		$	10,698		$	11,486		$	7,363		$	10,154		$	8,233		$	8,647
Cost of recurring revenue		1,651			1,723			1,404			1,573			1,566			1,679			1,631			1,516
Cost of services revenue		2,956			2,964			2,686			2,428			2,381			2,790			2,539			2,177
Cost of third-party technology		76			78			79			67			9			41			2			129
Amortization of acquired intangible assets		46			47			46			46			56			91			162			162
Net loss		(4,522	)		(3,214	)		(1,227	)		(845	)		(5,442	)		(3,804	)		(3,309	)		(3,001	)
Net loss per share—basic and diluted		(0.09	)		(0.06	)		(0.02	)		(0.02	)		(0.10	)		(0.07	)		(0.06	)		(0.06	)


	Health and Life Sciences			Industry Solutions			Unallocated			Totals
	(Amounts in thousands)
At and for the year ended December 31, 2008:
Net revenues	$	29,066		$	5,331		$	—		$	34,397
Segment loss		(12,879	)		(2,677	)		—			(15,556	)
Segment assets		23,829			1,447			5,951			31,227
Goodwill		3,871			—			5,951			9,822

At and for the year ended December 31, 2007:
Net revenues	$	31,358		$	9,194		$	—		$	40,552
Segment loss		(2,003	)		(7,805	)		—			(9,808	)
Segment assets		39,443			2,273			5,951			47,667
Goodwill		2,716			—			5,951			8,667

At and for the year ended December 31, 2006:
Net revenues	$	21,886		$	7,689		$	—		$	29,575
Segment loss		(2,704	)		(12,955	)		(156	)		(15,815	)
Segment assets		28,013			3,021			5,951			36,985
Goodwill		2,716			—			5,951			8,667


	Revenue*						Long-lived Assets
	2006		2007		2008		2006		2007		2008
							(Amounts in thousands)
United States	88	%	93	%	96	%	$	10,327	$	11,527	$	14,828
United Kingdom	3	%	2	%	3	%		460		332		223
The Netherlands	7	%	3	%	—			—		—		—
Canada	1	%	1	%	1	%		—		—		—
India	—		—		—			—		8		162
Other	1	%	1	%	—			—		—		—

Total	100	%	100	%	100	%	$	10,787	$	11,867	$	15,213


	(Amounts in thousands)
Balance at January 1, 2006	$	525
Write-offs		(392	)
Currency translation adjustments		4

Balance at December 31, 2006		137
Provisions		20
Write-offs		(31	)
Currency translation adjustments		1

Balance at December 31, 2007		127
Provisions		1
Write-offs		(6	)
Currency translation adjustments		(15	)

Balance at December 31, 2008	$	107


	Employee Severance Costs			Lease Costs			Total
	(Amounts in thousands)
Balance at January 1, 2006	$	—		$	1,119		$	1,119
Restructuring provisions in 2006		—			103			103
Payments in 2006		—			(237	)		(237	)

Balances at December 31, 2006		—			985			985
Restructuring provisions in 2007		—			93			93
Payments in 2007		—			(239	)		(239	)

Balances at December 31, 2007		—			839			839
Restructuring provisions in 2008		641			259			900
Currency translation adjustments		—			(37	)		(37	)
Payments in 2008		(3	)		(259	)		(262	)

Balances at December 31, 2008	$	638		$	802		$	1,440

Current portion—included in accrued expenses							$	953

Noncurrent portion—included in other long-term liabilities							$	487


Plan Category	Number of securities to be issued upon exercise of outstanding options, warrants and rights	Weighted average exercise price of outstanding options, warrants and rights		Number of securities remaining available for future issuance under equity compensation plans (1)
Equity compensation plans approved by security holders	7,273,963	$	2.12	1,551,273
Equity compensation plans not approved by security holders(2)	156,322	$	1.59	774,780

Total	7,430,285	$	2.11	2,326,053


EXHIBIT NO.		DESCRIPTION
2.1(1)		Asset Purchase Agreement by and among the Registrant, Global Healthcare Exchange, LLC and Global Healthcare Exchange, Inc. dated January 5, 2008

2.2(2)		Agreement and Plan of Merger by and among the Registrant, I-many Demand Corp., Edge Dynamics, Inc. and Paul Holland as Stockholders’ Representative dated May 2, 2008

3.1(3)		Amended and Restated Certificate of Incorporation

3.2(4)		Amended and Restated Bylaws

4.1(3)		Specimen certificate for shares of common stock

4.2(2)		Description of capital stock (contained in the Certificate of Incorporation filed as Exhibit 3.1)

4.3(5)		Form of Convertible Note dated December 31, 2007

10.1(3)*		1994 Stock Plan

10.2(3)*		1997 Stock Option/Incentive Plan

10.3(3)*		2000 Stock Incentive Plan

10.4(3)*		2000 Non-Employee Director Stock Option Plan

10.5(6)*		2001 Stock Incentive Plan

10.6(7)*		2001 Employee Stock Plan

10.7(8)*		2003 Stock Incentive Plan


EXHIBIT NO.		DESCRIPTION
10.8(9)*		2008 Stock Incentive Plan

10.9(10)*		Employment Agreement, dated January 15, 2007, between Registrant and John A. Rade

10.10*		Amendment to Employment Agreement between the Registrant and John A. Rade, dated March 4, 2009

10.11*		Severance Agreement, dated March 6, 2009, between Registrant and Kevin M. Harris.

10.12(11)*		Severance Agreement between the Registrant and Lawrence Lindsey dated June 4, 2008

10.13*		Amendment to Severance Agreement between the Registrant and Lawrence Lindsey, dated March 4, 2009

10.14(4)*		Amended and Restated Severance Agreement between the Registrant and Robert G. Schwartz, Jr., dated February 8, 2007

10.15*		Amendment to Severance Agreement between the Registrant and Robert G. Schwartz, Jr., dated March 3, 2009

10.16(12)*		Severance Agreement between the Registrant and A. Todd Shytle, dated December 5, 2006

10.17*		Amendment to Severance Agreement between the Registrant and A. Todd Shytle, dated March 4, 2009

10.18(13)*		Severance Agreement between the Registrant and Michael Zuckerman dated March 8, 2007

10.19*		Amendment to Severance Agreement between the Registrant and Michael Zuckerman, dated March 4, 2009

10.20(14)		Form of Warrant Agreement, dated November 1, 2006

14.1(15)		Amended and Restated I-many, Inc. Code of Business Conduct and Ethics

21.1		Subsidiaries of the Registrant

23.1		Consent of BDO Seidman, LLP, Independent Registered Public Accounting firm

24.1		Power of Attorney (see signature page)

31.1		Certification of Chief Executive Officer pursuant to Rules 13a-14(a) and 15d-14(a) of the Exchange Act, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

31.2		Certification of Chief Financial Officer pursuant to Rules 13a-14(a) and 15d-14(a) of the Exchange Act, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

32.1		Sarbanes-Oxley Act of 2002 Section 906 Certifications

99.1		Audit Committee Charter


SIGNATURE	TITLE	DATE

/s/ JOHN A. RADE John A. Rade	Chief Executive Officer, Chairman of the Board of Directors and President (principal executive officer)	March 30, 2009

/s/ KEVIN M. HARRIS Kevin M. Harris	Chief Financial Officer and Treasurer (principal financial officer and principal accounting officer)	March 30, 2009

/s/ REYNOLDS C. BISH Reynolds C. Bish	Director	March 30, 2009

/s/ JAMES H. DENNEDY James H. Dennedy	Director	March 30, 2009

/s/ STEVEN L. FINGERHOOD Steven L. Fingerhood	Director	March 30, 2009

Murray B. Low	Director