The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 220,524 2,325,959 SH   SOLE 0 2,325,959 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 13,563 485,100 SH   SOLE 0 485,100 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 4,390 1,425,439 SH   SOLE 0 1,425,439 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 4,415 325,599 SH   SOLE 0 325,599 0 0
ALCOBRA LTD SHS M2239P109 963 254,188 SH   SOLE 0 254,188 0 0
ALIGN TECHNOLOGY INC COM 016255101 2,018 27,757 SH   SOLE 0 27,757 0 0
ALIMERA SCIENCES INC COM 016259103 5,274 3,013,793 SH   SOLE 0 3,013,793 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 68,005 2,906,194 SH   SOLE 0 2,906,194 0 0
AMICUS THERAPEUTICS INC COM 03152W109 30,007 3,551,173 SH   SOLE 0 3,551,173 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 118,608 2,219,042 SH   SOLE 0 2,219,042 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 14,367 2,248,317 SH   SOLE 0 2,248,317 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 110,552 1,340,347 SH   SOLE 0 1,340,347 0 0
CELGENE CORP COM 151020104 27,104 270,800 SH   SOLE 0 270,800 0 0
CEMPRA INC COM 15130J109 21,301 1,215,833 SH   SOLE 0 1,215,833 0 0
CLOVIS ONCOLOGY INC COM 189464100 66,458 3,461,365 SH   SOLE 0 3,461,365 0 0
CYTOKINETICS INC COM NEW 23282W605 872 123,686 SH   SOLE 0 123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 1,436 267,890 SH   SOLE 0 267,890 0 0
ENDO INTL PLC SHS G30401106 23,326 828,630 SH   SOLE 0 828,630 0 0
EPIZYME INC COM 29428V104 32,184 2,655,479 SH   SOLE 0 2,655,479 0 0
EXACT SCIENCES CORP COM 30063P105 2,671 396,276 SH   SOLE 0 396,276 0 0
GILEAD SCIENCES INC COM 375558103 27,824 302,900 SH   SOLE 0 302,900 0 0
HEARTWARE INTL INC COM 422368100 7,914 251,868 SH   SOLE 0 251,868 0 0
HISTOGENICS CORP COM 43358V109 1,041 454,545 SH   SOLE 0 454,545 0 0
IDERA PHARMACEUTICALS INC COM NEW 45168K306 2,490 1,257,748 SH   SOLE 0 1,257,748 0 0
INSMED INC COM PAR $.01 457669307 60,699 4,790,800 SH   SOLE 0 4,790,800 0 0
INTREXON CORP COM 46122T102 1,596 47,100 SH   SOLE 0 47,100 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 27,635 3,098,145 SH   SOLE 0 3,098,145 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 318 59,017 SH   SOLE 0 59,017 0 0
MEDIVATION INC COM 58501N101 24,161 525,462 SH   SOLE 0 525,462 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 13,571 1,468,776 SH   SOLE 0 1,468,776 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 941 1,673,024 SH   SOLE 0 1,673,024 0 0
PROTHENA CORP PLC SHS G72800108 28,628 695,518 SH   SOLE 0 695,518 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 10,880 5,230,919 SH   SOLE 0 5,230,919 0 0
SEQUENOM INC COM NEW 817337405 14,134 10,023,842 SH   SOLE 0 10,023,842 0 0
SHIRE PLC SPONSORED ADR 82481R106 18,239 106,100 SH   SOLE 0 106,100 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 711 494,000 SH   SOLE 0 494,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 19,523 2,641,875 SH   SOLE 0 2,641,875 0 0
SUNESIS PHARMACEUTICALS INC COM NEW 867328601 3,766 6,974,854 SH   SOLE 0 6,974,854 0 0
UNIQURE NV SHS N90064101 243 20,453 SH   SOLE 0 20,453 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 170,004 1,525,654 SH   SOLE 0 1,525,654 0 0
VANDA PHARMACEUTICALS INC COM 921659108 33,698 4,030,908 SH   SOLE 0 4,030,908 0 0
WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 36,370 2,190,957 SH   SOLE 0 2,190,957 0 0
ZELTIQ AESTHETICS INC COM 98933Q108 15,580 573,636 SH   SOLE 0 573,636 0 0
ZOGENIX INC COM NEW 98978L204 264 28,600 SH   SOLE 0 28,600 0 0