The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACTIVISION BLIZZARD INC COM 00507V109 39,630 1,000,000 SH   DFND 1 1,000,000 0 0
AGNICO EAGLE MINES LTD COM 008474108 67,442 1,260,600 SH   DFND 1 1,260,600 0 0
ALLERGAN PLC SHS G0177J108 912,448 3,948,451 SH   DFND 1 3,948,451 0 0
ALLERGAN PLC COM G0177J108 49,615 214,700 SH Call DFND 1 214,700 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 31,292 268,000 SH   DFND 1 268,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 1,071 19,300 SH   DFND 1 19,300 0 0
AMERICAN CAP LTD COM 02503Y103 66,880 4,224,900 SH   DFND 1 4,224,900 0 0
AMERICAN INTL GROUP INC COM NEW 026874784 479,189 9,060,100 SH   DFND 1 9,060,100 0 0
ANGLOGOLD ASHANTI LTD SPONSORED ADR 035128206 231,531 12,820,100 SH   DFND 1 12,820,100 0 0
AKORN INC COM 009728106 256,732 9,012,900 SH   DFND 1 9,012,900 0 0
ARADIGM CORP COM NO PAR NEW 038505400 288 65,903 SH   DFND 1 65,903 0 0
B/E AEROSPACE INC COM 073302101 45,279 980,600 SH   DFND 1 980,600 0 0
BANK OF AMERICA CORPORATION * W Exp 01/16/2019 060505146 45,089 12,956,579 SH   DFND 1 12,956,579 0 0
BANK OF AMERICA CORPORATION * W Exp 10/28/2018 060505153 696 8,960,537 SH   DFND 1 8,960,537 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 747 263,100 SH   DFND 1 263,100 0 0
BIOGEN INC COM 09062X103 29,768 123,100 SH   DFND 1 123,100 0 0
BOSTON SCIENTIFIC CORP COM 101137107 2,197 94,000 SH   DFND 1 94,000 0 0
CAESARS ACQUISITION CO CL A 12768T103 147,443 13,141,098 SH   DFND 1 13,141,098 0 0
CAESARS ENTMT CORP COM 127686103 111,051 14,441,000 SH   DFND 1 14,441,000 0 0
CELLDEX THERAPEUTICS INC NEW COM 15117B103 311 70,800 SH   DFND 1 70,800 0 0
CIGNA CORPORATION COM 125509109 7,910 61,800 SH   DFND 1 61,800 0 0
COBALT INTL ENERGY INC COM 19075F106 52,389 39,096,300 SH   DFND 1 39,096,300 0 0
COBALT INTL ENERGY INC NOTE 2.625%12/0 19075FAA4 36,848 98,260,000 SH   DFND 1 98,260,000 0 0
COBALT INTL ENERGY INC NOTE 3.125% 5/1 19075FAB2 72,346 219,229,000 SH   DFND 1 219,229,000 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 10,604 880,000 SH Put DFND 1 880,000 0 0
DEXCOM INC COM 252131107 9,797 123,500 SH   DFND 1 123,500 0 0
DYNAVAX TECHNOLOGIES CORP COM 268158201 2,537 174,000 SH   DFND 1 174,000 0 0
DEMANDWARE INC COM 24802Y105 4,871 65,027 SH   DFND 1 65,027 0 0
EAGLE PHARMACEUTICALS INC COM 269796108 815 21,000 SH   DFND 1 21,000 0 0
E M C CORP MASS COM 268648102 272,939 10,045,606 SH   DFND 1 10,045,606 0 0
ENDO INTL PLC SHS G30401106 139,629 8,956,300 SH   DFND 1 8,956,300 0 0
ENDO INTL PLC COM G30401106 1,869 119,900 SH Call DFND 1 119,900 0 0
ENZYMOTEC LTD SHS M4059L101 35,314 4,224,139 SH   DFND 1 4,224,139 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 1,008 102,000 SH   DFND 1 102,000 0 0
ETSY INC COM 29786A106 11,737 1,223,910 SH   DFND 1 1,223,910 0 0
EXPEDIA INC DEL COM NEW 30212P303 9,482 89,200 SH   DFND 1 89,200 0 0
EXTENDED STAY AMER INC UNIT 99/99/9999B 30224P200 637,791 42,661,591 SH   DFND 1 42,661,591 0 0
FACEBOOK INC CL A 30303M102 16,502 144,400 SH   DFND 1 144,400 0 0
FEDEX CORP COM 31428X106 11,050 72,800 SH   DFND 1 72,800 0 0
FELCOR LODGING TR INC COM 31430F101 5,919 950,000 SH   DFND 1 950,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 122,444 7,345,166 SH   DFND 1 7,345,166 0 0
IAMGOLD CORP COM 450913108 15,997 3,863,912 SH   DFND 1 3,863,912 0 0
INGRAM MICRO INC CL A 457153104 4,692 134,900 SH   DFND 1 134,900 0 0
INSMED INC COM PAR $.01 457669307 2,023 205,200 SH   DFND 1 205,200 0 0
INTERNATIONAL TOWER HILL MIN COM 46050R102 20,291 23,058,000 SH   DFND 1 23,058,000 0 0
ITC HLDGS CORP COM 465685105 3,722 79,500 SH   DFND 1 79,500 0 0
JOHNSON & JOHNSON COM 478160104 15,526 128,000 SH   DFND 1 128,000 0 0
K2M GROUP HLDGS INC COM 48273J107 737 47,500 SH   DFND 1 47,500 0 0
KAMADA LTD SHS M6240T109 2,702 736,117 SH   DFND 1 736,117 0 0
LIVANOVA PLC SHS G5509L101 13,060 260,000 SH   DFND 1 260,000 0 0
LOXO ONCOLOGY INC COM 548862101 5,803 250,341 SH   DFND 1 250,341 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 508,794 8,371,080 SH   DFND 1 8,371,080 0 0
MCKESSON CORP COM 58155Q103 11,292 60,500 SH   DFND 1 60,500 0 0
MGIC INVT CORP WIS NOTE 2.000% 4/0 552848AE3 127,095 114,500,000 SH   DFND 1 114,500,000 0 0
MYLAN N V SHS EURO N59465109 952,493 22,028,061 SH   DFND 1 22,028,061 0 0
MYLAN N V SHS EURO N59465109 44,554 1,030,400 SH Call DFND 1 1,030,400 0 0
NOVACOPPER INC COM 66988K102 5,812 11,623,451 SH   DFND 1 11,623,451 0 0
NOVAGOLD RES INC COM NEW 66987E206 157,317 25,705,396 SH   DFND 1 25,705,396 0 0
OASIS PETE INC NEW COM 674215108 49,382 5,287,167 SH   DFND 1 5,287,167 0 0
OFFICE DEPOT INC COM 676220106 51,999 15,709,757 SH   DFND 1 15,709,757 0 0
OVERSEAS SHIPHOLDING GROUP I CL A NEW ADDED 69036R863 496 45,139 SH   DFND 1 45,139 0 0
PERRIGO CO PLC SHS G97822103 1,133 12,500 SH   DFND 1 12,500 0 0
PFIZER INC COM 717081103 17,971 510,400 SH   DFND 1 510,400 0 0
PRICELINE GRP INC COM NEW 741503403 2,122 1,700 SH   DFND 1 1,700 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 4,343 145,800 SH   DFND 1 145,800 0 0
QUINTILES TRANSNATIO HLDGS COM 74876Y101 10,726 164,200 SH   DFND 1 164,200 0 0
RANDGOLD RES LTD ADR 752344309 56,020 500,000 SH   DFND 1 500,000 0 0
REALOGY HLDGS CORP COM 75605Y106 138,861 4,785,000 SH   DFND 1 4,785,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 2,229 999,700 SH   DFND 1 999,700 0 0
RITE AID CORP COM 767754104 4,351 580,900 SH   DFND 1 580,900 0 0
SANOFI SPONSORED ADR 80105N105 16,552 395,500 SH   DFND 1 395,500 0 0
SHIRE PLC SPONSORED ADR 82481R106 956,222 5,194,600 SH   DFND 1 5,194,600 0 0
SHIRE PLC SPONSORED ADR 82481R106 16,199 88,000 SH Call DFND 1 88,000 0 0
SPDR GOLD TRUST GOLD SHS 78463V107 603,896 4,775,012 SH   DFND 1 4,775,012 0 0
STARWOOD HOTELS&RESORTS WRLD COM 85590A401 332,514 4,496,476 SH   DFND 1 4,496,476 0 0
ST JUDE MED INC COM 790849103 3,549 45,500 SH   DFND 1 45,500 0 0
SYNERGY PHARMACEUTICALS DEL COM NEW 871639308 105,475 27,756,668 SH   DFND 1 27,756,668 0 0
SYNTHESIS ENERGY SYS INC COM 871628103 10,500 10,000,000 SH   DFND 1 10,000,000 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 37,920 1,000,000 SH   DFND 1 1,000,000 0 0
TEVA PHARMACEUTICAL INDS LTD ADR 881624209 842,548 16,773,800 SH   DFND 1 16,773,800 0 0
TIM PARTICIPACOES S A SPONSORED ADR 88706P205 61,826 5,860,300 SH   DFND 1 5,860,300 0 0
T MOBILE US INC COM 872590104 42,400 979,900 SH   DFND 1 979,900 0 0
VALEANT PHARMACEUTICALS INTL COM 91911K102 384,110 19,072,000 SH   DFND 1 19,072,000 0 0
VANDA PHARMACEUTICALS INC COM 921659108 43,246 3,864,717 SH   DFND 1 3,864,717 0 0
VMWARE INC CL A COM 928563402 112,844 1,972,100 SH   DFND 1 1,972,100 0 0
LYON WILLIAM HOMES CL A NEW 552074700 53,561 3,322,666 SH   DFND 1 3,322,666 0 0