The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Acadia Pharmaceuticals Inc. | COM | 004225108 | 362,186 | 19,955,126 | SH | SOLE | 19,955,126 | 0 | 0 | ||
| Achillion | COM | 00448Q201 | 3,722 | 455,000 | SH | SOLE | 455,000 | 0 | 0 | ||
| Aegerion Pharmaceuticals | COM | 00767E102 | 58,548 | 924,343 | SH | SOLE | 924,343 | 0 | 0 | ||
| Ambit Biosciences Corp. | COM | 02318X100 | 5,236 | 747,962 | SH | SOLE | 747,962 | 0 | 0 | ||
| Amicus Therapeutics | COM | 03152W109 | 1,200 | 515,072 | SH | SOLE | 515,072 | 0 | 0 | ||
| Anacor Pharmaceuticals | COM | 32420101 | 4,899 | 876,463 | SH | SOLE | 876,463 | 0 | 0 | ||
| Aradigm Corp. | COM | 038505301 | 16 | 100,000 | SH | SOLE | 100,000 | 0 | 0 | ||
| Ariad Pharmaceuticals Inc. | COM | 04033A100 | 25,361 | 1,450,000 | SH | SOLE | 1,450,000 | 0 | 0 | ||
| Arqule Inc. | COM | 04269E107 | 2,041 | 879,805 | SH | SOLE | 879,805 | 0 | 0 | ||
| Array Biopharma Inc. | COM | 04269X105 | 6,810 | 1,500,000 | SH | SOLE | 1,500,000 | 0 | 0 | ||
| Avanir Pharmaceuticals | COM | 05348P401 | 16,462 | 3,578,591 | SH | SOLE | 3,578,591 | 0 | 0 | ||
| Biocryst Pharmaceuticals Inc. | COM | 09058V103 | 8,623 | 5,563,615 | SH | SOLE | 5,563,615 | 0 | 0 | ||
| Biodel Inc. | COM | 09064M204 | 961 | 229,885 | SH | SOLE | 229,885 | 0 | 0 | ||
| BioDelivery Sciences Intl. Inc. | COM | 09060J106 | 3,656 | 900,505 | SH | SOLE | 900,505 | 0 | 0 | ||
| Biomarin Pharmaceuticals | COM | 09061G101 | 43,662 | 783,311 | SH | SOLE | 783,311 | 0 | 0 | ||
| Cerus | COM | 157085101 | 37,372 | 8,455,306 | SH | SOLE | 8,455,306 | 0 | 0 | ||
| Chelsea Therapeutics | COM | 163428105 | 10,984 | 4,775,787 | SH | SOLE | 4,775,787 | 0 | 0 | ||
| Chemocentryx Inc. | COM | 16383L106 | 5,303 | 375,000 | SH | SOLE | 375,000 | 0 | 0 | ||
| Clovis Oncology | COM | 189464100 | 35,172 | 525,113 | SH | SOLE | 525,113 | 0 | 0 | ||
| Cyclacel Pharmaceuticals Pfd. Conv. Ex 6% | PFD CONV EX | 23254L207 | 151 | 20,979 | SH | SOLE | 20,979 | 0 | 0 | ||
| Cytrx Corp. | COM | 232828509 | 2,000 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| Cubist Pharmaceuticals Inc. | COM | 229678107 | 241 | 5,000 | SH | SOLE | 5,000 | 0 | 0 | ||
| Derma Sciences | COM | 249827502 | 18,141 | 1,358,857 | SH | SOLE | 1,358,857 | 0 | 0 | ||
| Discovery Laboratories Inc. | COM | 254668403 | 2,308 | 1,518,617 | SH | SOLE | 1,518,617 | 0 | 0 | ||
| Enanta Pharmaceuticals | COM | 29251M106 | 2,214 | 125,000 | SH | SOLE | 125,000 | 0 | 0 | ||
| Epizyme Inc. | COM | 29428V104 | 563 | 20,000 | SH | SOLE | 20,000 | 0 | 0 | ||
| Genomic Health Inc. | COM | 37244C101 | 432,868 | 13,650,835 | SH | SOLE | 13,650,835 | 0 | 0 | ||
| Geron Corp. | COM | 374163103 | 1,500 | 1,000,000 | SH | SOLE | 1,000,000 | 0 | 0 | ||
| Gilead Sciences Inc. | COM | 375558103 | 63,872 | 1,245,800 | SH | SOLE | 1,245,800 | 0 | 0 | ||
| Halozyme Therapeutics Inc. | COM | 40637H109 | 52,098 | 6,553,150 | SH | SOLE | 6,553,150 | 0 | 0 | ||
| Idera Pharmaceuticals Inc. | COM | 45168K306 | 2,948 | 4,500,000 | SH | SOLE | 4,500,000 | 0 | 0 | ||
| Incyte Corp. | COM | 45337C102 | 325,832 | 14,810,559 | SH | SOLE | 14,810,559 | 0 | 0 | ||
| Infinity Pharmaceuticals Inc. | COM | 45665G303 | 16,458 | 1,016,433 | SH | SOLE | 1,016,433 | 0 | 0 | ||
| Insmed Inc. | COM | 457669307 | 9,518 | 795,803 | SH | SOLE | 795,803 | 0 | 0 | ||
| Intercept Pharmaceuticals, Inc. | COM | 45845P108 | 20,754 | 462,847 | SH | SOLE | 462,847 | 0 | 0 | ||
| Ironwood Pharmaceuticals | COM | 46333X108 | 9,157 | 922,160 | SH | SOLE | 922,160 | 0 | 0 | ||
| Isis Pharmaceuticals | COM | 464330109 | 6,638 | 247,036 | SH | SOLE | 247,036 | 0 | 0 | ||
| Kythera Biopharmaceuticals | COM | 501570105 | 4,463 | 165,000 | SH | SOLE | 165,000 | 0 | 0 | ||
| Ligand Pharmaceuticals Inc. | CLASS B | 53220K207 | 2,745 | 73,400 | SH | SOLE | 73,400 | 0 | 0 | ||
| Lpath Inc. | COM | 548910306 | 880 | 200,000 | SH | SOLE | 200,000 | 0 | 0 | ||
| Medivation Inc. | COM | 58501N101 | 19,598 | 398,331 | SH | SOLE | 398,331 | 0 | 0 | ||
| MEI Pharma, Inc. | COM | 55279B103 | 3,677 | 515,612 | SH | SOLE | 515,612 | 0 | 0 | ||
| Orasure Technologies Inc. | COM | 68554V108 | 945 | 243,467 | SH | SOLE | 243,467 | 0 | 0 | ||
| Pharmacyclics Inc. | COM | 716933106 | 855,982 | 10,771,138 | SH | SOLE | 10,771,138 | 0 | 0 | ||
| Portola Pharmaceuticals, Inc. | COM | 737010108 | 9,826 | 399,914 | SH | SOLE | 399,914 | 0 | 0 | ||
| Progenics Pharmaceuticals, Inc. | COM | 743187106 | 18,732 | 4,200,000 | SH | SOLE | 4,200,000 | 0 | 0 | ||
| Prothena Corp. PLC | COM | G72800108 | 4,772 | 369,650 | SH | SOLE | 369,650 | 0 | 0 | ||
| Puma Biotechnology | COM | 74587V107 | 3,697 | 83,333 | SH | SOLE | 83,333 | 0 | 0 | ||
| QLT, Inc. | COM | 746927102 | 6,742 | 1,535,863 | SH | SOLE | 1,535,863 | 0 | 0 | ||
| Questcor Pharmaceuticals, Inc. | COM | 74835Y101 | 14,352 | 315,846 | SH | SOLE | 315,846 | 0 | 0 | ||
| Receptos Inc. | COM | 756207106 | 1,989 | 100,000 | SH | SOLE | 100,000 | 0 | 0 | ||
| Repros Therapeutics | COM | 76028H209 | 51,266 | 2,778,654 | SH | SOLE | 2,778,654 | 0 | 0 | ||
| Salix Pharmaceuticals, Inc. | COM | 795435106 | 3,015 | 45,571 | SH | SOLE | 45,571 | 0 | 0 | ||
| Seattle Genetics Inc. | COM | 812578102 | 607,900 | 19,322,947 | SH | SOLE | 19,322,947 | 0 | 0 | ||
| Stemline Therapeutics Inc. | COM | 85858C107 | 21,456 | 900,000 | SH | SOLE | 900,000 | 0 | 0 | ||
| Synageva Biopharma Corp. | COM | 87159A103 | 387,189 | 9,223,182 | SH | SOLE | 9,223,182 | 0 | 0 | ||
| Synergy Pharmaceuticals | COM | 871639308 | 11,268 | 2,608,271 | SH | SOLE | 2,608,271 | 0 | 0 | ||
| Synta Pharmaceuticals | COM | 87162T206 | 6,981 | 1,399,040 | SH | SOLE | 1,399,040 | 0 | 0 | ||
| Tesaro Inc. | COM | 881569107 | 1,022 | 31,218 | SH | SOLE | 31,218 | 0 | 0 | ||
| Threshold Pharma | COM | 885807107 | 8,390 | 1,595,048 | SH | SOLE | 1,595,048 | 0 | 0 | ||
| Vanda Pharmaceuticals, Inc. | COM | 921659108 | 32,047 | 3,966,179 | SH | SOLE | 3,966,179 | 0 | 0 | ||
| Ventrus Biosciences, Inc. | COM | 922822101 | 2,918 | 1,215,840 | SH | SOLE | 1,215,840 | 0 | 0 | ||
| Viropharma Inc. | COM | 928241108 | 244,344 | 8,528,603 | SH | SOLE | 8,528,603 | 0 | 0 | ||
| Xenoport | COM | 98411C100 | 5,119 | 1,034,112 | SH | SOLE | 1,034,112 | 0 | 0 | ||
| Xoma Corp. | COM | 98419J107 | 73,597 | 20,274,581 | SH | SOLE | 20,274,581 | 0 | 0 | ||
| Ziopharm Oncology Inc. | COM | 98973P101 | 536 | 254,199 | SH | SOLE | 254,199 | 0 | 0 | ||
| Zogenix, Inc. | COM | 98978L105 | 3,422 | 2,001,000 | SH | SOLE | 2,001,000 | 0 | 0 | ||
| Auxilium 1.5% 7/15/2018 | CONV BONDS | 05334DAA5 | 88,098 | 91,590,000 | PRN | SOLE | 91,590,000 | 0 | 0 | ||
| Biomarin Pharmaceuticals Notes 1.875% 4/23/2017 | CONV BONDS | 09061GAD3 | 63,217 | 22,898,000 | PRN | SOLE | 22,898,000 | 0 | 0 | ||
| Gilead 1.625% 5/1/16 | CONV BONDS | 375558AP8 | 48,664 | 21,500,000 | PRN | SOLE | 21,500,000 | 0 | 0 | ||
| Incyte Genomics Notes 4.75% 10/1/2015 | CONV BONDS | 45337CAH5 | 401,692 | 157,758,000 | PRN | SOLE | 15,775,800 | 0 | 0 | ||
| Intermune Inc Notes 5% 3/1/15 | CONV BONDS | 45884XAD5 | 17,756 | 16,860,000 | PRN | SOLE | 16,860,000 | 0 | 0 | ||
| Intermune Inc Notes 2.5% 12/15/17 | CONV BONDS | 45884XAF0 | 43,896 | 41,000,000 | PRN | SOLE | 41,000,000 | 0 | 0 | ||
| Medivation 2.625% 4/1/17 | CONV BONDS | 58501NAA9 | 50,054 | 39,500,000 | PRN | SOLE | 39,500,000 | 0 | 0 | ||
| Salix 2.75% 5/15/15 | CONV BONDS | 795435AC0 | 334,029 | 219,440,000 | PRN | SOLE | 21,944,000 | 0 | 0 | ||