The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 177,062 2,473,624 SH   SOLE 0 2,473,624 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 8,244 2,135,739 SH   SOLE 0 2,135,739 0 0
ALCOBRA LTD SHS M2239P109 412 73,188 SH   SOLE 0 73,188 0 0
ALIGN TECHNOLOGY INC COM 016255101 15,170 282,057 SH   SOLE 0 282,057 0 0
ALIMERA SCIENCES INC COM 016259103 15,099 3,013,793 SH   SOLE 0 3,013,793 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 119,544 2,187,041 SH   SOLE 0 2,187,041 0 0
AMICUS THERAPEUTICS INC COM 03152W109 21,285 1,956,376 SH   SOLE 0 1,956,376 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 188,536 3,259,045 SH   SOLE 0 3,259,045 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 18,389 2,231,717 SH   SOLE 0 2,231,717 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 205,597 1,649,792 SH   SOLE 0 1,649,792 0 0
BIOSPECIFICS TECHNOLOGIES CO COM 090931106 1,975 50,436 SH   SOLE 0 50,436 0 0
CELGENE CORP COM 151020104 28,751 249,400 SH   SOLE 0 249,400 0 0
CELLADON CORP COM 15117E107 27,370 1,445,100 SH   SOLE 0 1,445,100 0 0
CLOVIS ONCOLOGY INC COM 189464100 157,505 2,121,857 SH   SOLE 0 2,121,857 0 0
CYBERONICS INC COM 23251P102 26,747 412,000 SH   SOLE 0 412,000 0 0
CYTOKINETICS INC COM NEW 23282W605 839 123,686 SH   SOLE 0 123,686 0 0
ENDO INTL PLC SHS G30401106 77,160 860,204 SH   SOLE 0 860,204 0 0
EXACT SCIENCES CORP COM 30063P105 8,647 392,676 SH   SOLE 0 392,676 0 0
GILEAD SCIENCES INC COM 375558103 28,556 291,000 SH   SOLE 0 291,000 0 0
HEARTWARE INTL INC COM 422368100 21,404 243,868 SH   SOLE 0 243,868 0 0
HISTOGENICS CORP COM 43358V109 4,541 454,545 SH   SOLE 0 454,545 0 0
IDERA PHARMACEUTICALS INC COM NEW 45168K306 4,342 1,170,248 SH   SOLE 0 1,170,248 0 0
INSMED INC COM PAR $.01 457669307 96,709 4,649,448 SH   SOLE 0 4,649,448 0 0
INTREXON CORP COM 46122T102 2,137 47,100 SH   SOLE 0 47,100 0 0
INTUITIVE SURGICAL INC COM NEW 46120e602 16,338 32,350 SH   SOLE 0 32,350 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 29,111 951,032 SH   SOLE 0 951,032 0 0
KYTHERA BIOPHARMACEUTICALS I COM 501570105 69,344 1,382,722 SH   SOLE 0 1,382,722 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 454 3,588 SH   SOLE 0 3,588 0 0
MEDIVATION INC COM 58501N101 22,161 171,700 SH   SOLE 0 171,700 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 22,119 1,455,176 SH   SOLE 0 1,455,176 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 15,122 1,931,324 SH   SOLE 0 1,931,324 0 0
PROTHENA CORP PLC SHS G72800108 26,542 695,918 SH   SOLE 0 695,918 0 0
QLT INC COM 746927102 1,235 315,906 SH   SOLE 0 315,906 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 18,479 5,176,319 SH   SOLE 0 5,176,319 0 0
SALIX PHARMACEUTICALS INC COM 795435106 916 5,300 SH   SOLE 0 5,300 0 0
SEQUENOM INC COM NEW 817337405 39,412 9,977,642 SH   SOLE 0 9,977,642 0 0
SHIRE PLC SPONSORED ADR 82481R106 22,733 95,000 SH   SOLE 0 95,000 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 111 191,600 SH   SOLE 0 191,600 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 19,637 2,642,922 SH   SOLE 0 2,642,922 0 0
SUNESIS PHARMACEUTICALS INC COM NEW 867328601 1,478 603,400 SH   SOLE 0 603,400 0 0
THORATEC CORP COM NEW 885175307 106,325 2,538,203 SH   SOLE 0 2,538,203 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 246,570 1,429,928 SH   SOLE 0 1,429,928 0 0
VANDA PHARMACEUTICALS INC COM 921659108 35,372 3,803,408 SH   SOLE 0 3,803,408 0 0
WRIGHT MED GROUP INC COM 98235T107 52,871 2,049,251 SH   SOLE 0 2,049,251 0 0
XOMA CORP DEL COM 98419J107 2,892 794,500 SH   SOLE 0 794,500 0 0
ZELTIQ AESTHETICS INC COM 98933Q108 17,525 568,436 SH   SOLE 0 568,436 0 0