The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 60,325 2,429,524 SH   SOLE 0 2,429,524 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 8,908 1,622,654 SH   SOLE 0 1,622,654 0 0
ALIGN TECHNOLOGY INC COM 016255101 11,013 213,100 SH   SOLE 0 213,100 0 0
ALIMERA SCIENCES INC COM 016259103 16,478 3,040,260 SH   SOLE 0 3,040,260 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 51,520 1,614,536 SH   SOLE 0 1,614,536 0 0
AMICUS THERAPEUTICS INC COM 03152W109 11,640 1,956,376 SH   SOLE 0 1,956,376 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 51,795 2,116,665 SH   SOLE 0 2,116,665 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 12,051 2,231,717 SH   SOLE 0 2,231,717 0 0
AUXILIUM PHARMACEUTICALS INC COM 05334D107 144,911 4,854,631 SH   SOLE 0 4,854,631 0 0
AVEO PHARMACEUTICALS INC COM 053588109 1,063 958,026 SH   SOLE 0 958,026 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 91,239 1,264,397 SH   SOLE 0 1,264,397 0 0
BIOSPECIFICS TECHNOLOGIES CO COM 090931106 1,247 35,336 SH   SOLE 0 35,336 0 0
CELGENE CORP COM 151020104 16,264 171,600 SH   SOLE 0 171,600 0 0
CELLADON CORP COM 15117E107 15,242 1,457,200 SH   SOLE 0 1,457,200 0 0
CLOVIS ONCOLOGY INC COM 189464100 78,099 1,721,757 SH   SOLE 0 1,721,757 0 0
CUBIST PHARMACEUTICALS INC COM 229678107 122,310 1,843,688 SH   SOLE 0 1,843,688 0 0
CYBERONICS INC COM 23251P102 82,936 1,621,101 SH   SOLE 0 1,621,101 0 0
CYTOKINETICS INC COM NEW 23282W605 435 123,686 SH   SOLE 0 123,686 0 0
EXACT SCIENCES CORP COM 30063P105 15,071 777,676 SH   SOLE 0 777,676 0 0
GERON CORP COM 374163103 2,323 1,161,400 SH   SOLE 0 1,161,400 0 0
GILEAD SCIENCES INC COM 375558103 17,830 167,500 SH   SOLE 0 167,500 0 0
HYPERION THERAPEUTICS INC COM 44915N101 1,581 62,700 SH   SOLE 0 62,700 0 0
INSMED INC COM PAR $.01 457669307 50,793 3,892,199 SH   SOLE 0 3,892,199 0 0
INTUITIVE SURGICAL INC COM NEW 46120e602 10,737 23,250 SH   SOLE 0 23,250 0 0
KYTHERA BIOPHARMACEUTICALS I COM 501570105 36,107 1,102,181 SH   SOLE 0 1,102,181 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 323 3,588 SH   SOLE 0 3,588 0 0
MEDIVATION INC COM 58501N101 12,863 130,100 SH   SOLE 0 130,100 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 16,502 1,455,176 SH   SOLE 0 1,455,176 0 0
NPS PHARMACEUTICALS INC COM 62936P103 44,189 1,699,562 SH   SOLE 0 1,699,562 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 8,227 1,931,324 SH   SOLE 0 1,931,324 0 0
PROTHENA CORP PLC SHS G72800108 14,932 673,818 SH   SOLE 0 673,818 0 0
QLT INC COM 746927102 8,344 1,846,075 SH   SOLE 0 1,846,075 0 0
REVANCE THERAPEUTICS INC COM 761330109 1,554 80,369 SH   SOLE 0 80,369 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 10,049 5,180,101 SH   SOLE 0 5,180,101 0 0
SEQUENOM INC COM NEW 817337405 29,137 9,810,442 SH   SOLE 0 9,810,442 0 0
SHIRE PLC SPONSORED ADR 82481R106 16,501 63,700 SH   SOLE 0 63,700 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 858 292,900 SH   SOLE 0 292,900 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 27,633 2,599,553 SH   SOLE 0 2,599,553 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 167,094 1,298,828 SH   SOLE 0 1,298,828 0 0
VANDA PHARMACEUTICALS INC COM 921659108 34,079 3,283,124 SH   SOLE 0 3,283,124 0 0
WRIGHT MED GROUP INC COM 98235T107 25,232 832,729 SH   SOLE 0 832,729 0 0
XOMA CORP DEL COM 98419J107 2,631 624,900 SH   SOLE 0 624,900 0 0
ZELTIQ AESTHETICS INC COM 98933Q108 6,433 284,249 SH   SOLE 0 284,249 0 0