The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ATYR PHARMA INC COM 002120103 889 279,425 SH   SOLE   279,425 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 8,347 90,215 SH   SOLE   90,215 0 0
CYCLACEL PHARMACEUTICALS INC COM 23254L405 2,159 359,900 SH   SOLE   359,900 0 0
HERON THERAPEUTICS INC COM 427746102 101,207 5,873,891 SH   SOLE   5,873,891 0 0
HERON THERAPEUTICS INC COM 427746102 5,571 323,307 SH   OTR 1 0 323,307 0
IGNYTA INC COM 451731103 24,989 3,972,800 SH   SOLE   3,972,800 0 0
LA JOLLA PHARMACEUTICAL CO COM 503459604 75,918 3,191,165 SH   SOLE   3,191,165 0 0
OPKO HEALTH INC DEBT 3.0% 2/1/33 68375NAB9 22,031 14,000,000 PRN   SOLE   14,000,000 0 0