The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABEONA THERAPEUTICS INC COM 00289Y107 600 100,000 SH   SOLE   100,000 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 4,103 250,000 SH   SOLE   250,000 0 0
AFFIMED N V COM N01045108 1,195 430,000 SH   SOLE   430,000 0 0
AGIOS PHARMACEUTICALS COM 00847X104 6,867 130,000 SH   SOLE   130,000 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 368 15,000 SH   SOLE   15,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 2,233 700,000 SH   SOLE   700,000 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 4,142 310,000 SH   SOLE   310,000 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 14,306 1,045,000 SH   SOLE   1,045,000 0 0
AXOGEN INC COM 05463X106 18,060 2,000,000 SH   SOLE   2,000,000 0 0
BIOLINERX LTD SPONSORED ADR 09071M106 288 250,000 SH   SOLE   250,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 23,315 785,000 SH   SOLE   785,000 0 0
CARA THERAPEUTICS INC COM 140755109 5,636 675,000 SH   SOLE   675,000 0 0
CHIMERIX INC COM 16934W106 4,321 780,000 SH   SOLE   780,000 0 0
CODEXIS INC COM 192005106 5,195 1,170,000 SH   SOLE   1,170,000 0 0
CORIUM INTL INC COM 21887L107 2,252 400,000 SH   SOLE   400,000 0 0
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR 23257Y859 5,029 125,000 SH   SOLE   125,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 2,509 160,000 SH   SOLE   160,000 0 0
DEPOMED INC COM 249908104 41 1,650 SH   SOLE   1,650 0 0
EAGLE PHARMACEUTICALS INC COM 269796108 4,900 70,000 SH   SOLE   70,000 0 0
EDGE THERAPEUTICS INC COM 279870109 2,915 280,000 SH   SOLE   280,000 0 0
FIBROGEN INC COM 31572Q808 6,831 330,000 SH   SOLE   330,000 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 5,834 630,000 SH   SOLE   630,000 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 4,610 200,000 SH   SOLE   200,000 0 0
HORIZON GLOBAL CORP COM G4617B105 4,986 275,000 SH   SOLE   275,000 0 0
IMMUNOMEDICS INC COM 452907108 3,900 1,200,000 SH   SOLE   1,200,000 0 0
IMPRIMIS PHARMACEUTICALS INC COM NEW 45323A201 4,631 1,215,381 SH   SOLE   1,215,381 0 0
INNOCOLL HLDGS PLC SHS G4783X105 1,563 269,100 SH   SOLE   269,100 0 0
INOTEK PHARMACEUTICALS CORP COM 45780VAA0 3,792 400,000 SH   SOLE   400,000 0 0
INTEC PHARMA LTD JERUSALEM COM M53644106 1,029 175,000 SH   SOLE   175,000 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 2,304 280,000 SH   SOLE   280,000 0 0
LOXO ONCOLOGY INC COM 548862101 2,880 110,000 SH   SOLE   110,000 0 0
MACROGENICS INC COM 556099109 4,337 145,000 SH   SOLE   145,000 0 0
MEDGENICS INC COM NEW 58436Q203 10,026 1,800,000 SH   SOLE   1,800,000 0 0
NABRIVA THERAPEUTICS AG SPONSORED ADR 62957M104 1,688 239,500 SH   SOLE   239,500 0 0
NEURODERM LTD ORD SHS M74231107 1,821 98,500 SH   SOLE   98,500 0 0
PORTOLA PHARMACEUTICALS INC COM 737010908 795 35,000 SH   SOLE   35,000 0 0
PROTALIX BIOTHERAPEUTICS INC COM 74365AAB7 4,600 8,070,000 SH   SOLE   8,070,000 0 0
PROTEOSTASIS THERAPEUTICS IN COM 74373B109 2,370 152,000 SH   SOLE   152,000 0 0
PROTHENA CORP PLC SHS G72800108 2,999 50,000 SH   SOLE   50,000 0 0
TENAX THERAPEUTICS INC COM 88032L100 905 390,000 SH   SOLE   390,000 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 2,587 175,000 SH   SOLE   175,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 2,483 35,000 SH   SOLE   35,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 3,321 410,000 SH   SOLE   410,000 0 0
ZOGENIX INC COM NEW 98978L105 2,515 220,000 SH   SOLE   220,000 0 0