The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACTIVISION BLIZZARD INC COM 00507V109 43,157 974,200 SH   DFND 1 974,200 0 0
AGNICO EAGLE MINES LTD COM 008474108 68,299 1,260,600 SH   DFND 1 1,260,600 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 2,425 74,000 SH   DFND 1 74,000 0 0
ALLERGAN PLC SHS G0177J108 896,167 3,891,134 SH   DFND 1 3,891,134 0 0
ALLERGAN PLC SHS G0177J108 49,448 214,700 SH Call DFND 1 214,700 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 27,902 227,700 SH   DFND 1 227,700 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 1,308 19,300 SH   DFND 1 19,300 0 0
AMERICAN CAPITAL LTD COM 02503Y103 73,241 4,331,200 SH   DFND 1 4,331,200 0 0
AMERICAN INTERNATIONAL GROUP COM NEW 026874784 537,626 9,060,100 SH   DFND 1 9,060,100 0 0
ANGLOGOLD ASHANTI-SPON ADR SPONSORED ADR 035128206 203,496 12,782,400 SH   DFND 1 12,782,400 0 0
AKORN INC COM 009728106 244,642 8,974,400 SH   DFND 1 8,974,400 0 0
ARADIGM CORP COM NO PAR NEW 038505400 1,011 146,918 SH   DFND 1 146,918 0 0
BANK OF AMERICA CORP-CW19 * W Exp 01/16/2019 060505146 59,621 12,905,026 SH   DFND 1 12,905,026 0 0
BANK OF AMERICA CORP-CW-B * W Exp 10/28/2018 060505153 894 8,944,186 SH   DFND 1 8,944,186 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 1,601 363,100 SH   DFND 1 363,100 0 0
BIOGEN INC COM 09062X103 96,413 308,000 SH   DFND 1 308,000 0 0
BOSTON SCIENTIFIC CORP COM 101137107 9,758 410,000 SH   DFND 1 410,000 0 0
CAESARS ACQUISITION CO-CL A CL A 12768T103 162,926 13,117,998 SH   DFND 1 13,117,998 0 0
CAESARS ENTERTAINMENT CORP COM 127686103 107,413 14,417,900 SH   DFND 1 14,417,900 0 0
CARMIKE CINEMAS INC COM 143436400 3,923 120,000 SH   DFND 1 120,000 0 0
CBOE HOLDINGS INC COM 12503M108 2,491 38,412 SH   DFND 1 38,412 0 0
CELLDEX THERAPEUTICS INC COM 15117B103 286 70,800 SH   DFND 1 70,800 0 0
COBALT INTERNATIONAL ENERGY COM 19075F106 38,711 31,218,927 SH   DFND 1 31,218,927 0 0
COBALT INTL ENERGY INC 2.625% 12/01/2019 NOTE 2.625%12/01/2019 19075FAA4 24,552 48,260,000 SH   DFND 1 48,260,000 0 0
COBALT INTL ENERGY INC 3.125% 05/15/2024 NOTE 3.125% 5/15/2024 19075FAB2 83,307 219,229,000 SH   DFND 1 219,229,000 0 0
COMMUNITY HEALTH SYS COM 203668108 14,714 1,275,000 SH Put DFND 1 1,275,000 0 0
CVS HEALTH CORP COM 126650100 10,875 122,200 SH   DFND 1 122,200 0 0
DELL TECHNOLOGIES INC-CL V COM CL V 24703L103 52,427 1,096,804 SH   DFND 1 1,096,804 0 0
DEXCOM INC COM 252131107 3,813 43,500 SH   DFND 1 43,500 0 0
DYNAVAX TECHNOLOGIES CORP COM 268158201 1,825 174,000 SH   DFND 1 174,000 0 0
EBAY INC COM 278642103 20,664 628,100 SH   DFND 1 628,100 0 0
ELI LILLY & CO COM 532457108 3,676 45,800 SH   DFND 1 45,800 0 0
ENDO INTERNATIONAL PLC SHS G30401106 160,271 7,953,900 SH   DFND 1 7,953,900 0 0
ENZYMOTEC LTD SHS M4059L101 29,442 4,205,980 SH   DFND 1 4,205,980 0 0
ESPERION THERAPEUTICS INC COM 29664W105 1,413 102,000 SH   DFND 1 102,000 0 0
ETSY INC COM 29786A106 17,936 1,256,000 SH   DFND 1 1,256,000 0 0
EXPEDIA INC COM NEW 30212P303 7,388 63,300 SH   DFND 1 63,300 0 0
EXTENDED STAY AMERICA INC UNIT 99/99/9999B 30224P200 535,031 37,678,258 SH   DFND 1 37,678,258 0 0
FACEBOOK INC-A CL A 30303M102 27,283 212,700 SH   DFND 1 212,700 0 0
FEDEX CORP COM 31428X106 18,656 106,800 SH   DFND 1 106,800 0 0
FELCOR LODGING TRUST INC COM 31430F101 3,215 500,000 SH   DFND 1 500,000 0 0
GRIFOLS SA-ADR SP ADR REP B NVT 398438408 39,583 2,478,600 SH   DFND 1 2,478,600 0 0
HCA HOLDINGS INC COM 40412C101 12,290 162,500 SH   DFND 1 162,500 0 0
HEWLETT PACKARD ENTERPRIS COM 42824C109 135,661 5,963,100 SH   DFND 1 5,963,100 0 0
HUMANA INC COM 444859102 14,063 79,500 SH   DFND 1 79,500 0 0
IAMGOLD CORP COM 450913108 15,649 3,863,912 SH   DFND 1 3,863,912 0 0
INFOBLOX INC COM 45672H104 6,065 230,000 SH   DFND 1 230,000 0 0
INGRAM MICRO INC-CL A CL A 457153104 5,174 145,086 SH   DFND 1 145,086 0 0
INSMED INC COM PAR $.01 457669307 2,980 205,200 SH   DFND 1 205,200 0 0
INTERNATIONAL TOWER HILL MINE COM 46050R102 20,517 23,058,000 SH   DFND 1 23,058,000 0 0
ITC HOLDINGS CORP COM 465685105 3,955 85,100 SH   DFND 1 85,100 0 0
JOHNSON & JOHNSON COM 478160104 4,135 35,000 SH   DFND 1 35,000 0 0
KAMADA LTD SHS M6240T109 3,749 730,800 SH   DFND 1 730,800 0 0
LIVANOVA PLC SHS G5509L101 16,656 277,100 SH   DFND 1 277,100 0 0
LIBERTY GLOBAL PLC LILAC - A LILAC SHS CL A G5480U138 138 4,990 SH   DFND 1 4,990 0 0
LOXO ONCOLOGY INC COM 548862101 19,293 736,941 SH   DFND 1 736,941 0 0
MALLINCKRODT PLC SHS G5785G107 556,459 7,974,472 SH   DFND 1 7,974,472 0 0
MARRIOTT INTERNATIONAL -CL A CL A 571903202 11,446 170,000 SH   DFND 1 170,000 0 0
MCKESSON CORP COM 58155Q103 11,172 67,000 SH   DFND 1 67,000 0 0
MEAD JOHNSON NUTRITION CO COM 582839106 6,202 78,500 SH   DFND 1 78,500 0 0
MERCADOLIBRE INC COM 58733R102 3,866 20,900 SH   DFND 1 20,900 0 0
MONSTER WORLDWIDE INC COM 611742107 7,220 2,000,000 SH   DFND 1 2,000,000 0 0
MYLAN NV SHS EURO N59465109 831,461 21,811,661 SH   DFND 1 21,811,661 0 0
MYLAN NV SHS EURO N59465109 35,848 940,400 SH Call DFND 1 940,400 0 0
NOVAGOLD RESOURCES INC COM NEW 66987E206 143,377 25,602,996 SH   DFND 1 25,602,996 0 0
OASIS PETROLEUM INC COM 674215108 59,737 5,208,100 SH   DFND 1 5,208,100 0 0
OFFICE DEPOT INC COM 676220106 54,873 15,370,657 SH   DFND 1 15,370,657 0 0
OVERSEAS SHIPHOLDING GROUP-A CL A NEW ADDED 69036R863 477 45,139 SH   DFND 1 45,139 0 0
PFIZER INC COM 717081103 8,535 252,000 SH   DFND 1 252,000 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 5,666 84,500 SH   DFND 1 84,500 0 0
RANDGOLD RESOURCES LTD-ADR ADR 752344309 50,035 500,000 SH   DFND 1 500,000 0 0
REALOGY HOLDINGS CORP COM 75605Y106 123,740 4,785,000 SH   DFND 1 4,785,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 2,954 805,000 SH   DFND 1 805,000 0 0
SANOFI-ADR SPONSORED ADR 80105N105 15,925 417,000 SH   DFND 1 417,000 0 0
SHIRE PLC-ADR SPONSORED ADR 82481R106 904,900 4,667,800 SH   DFND 1 4,667,800 0 0
SHIRE PLC-ADR SPONSORED ADR 82481R106 11,632 60,000 SH Call DFND 1 60,000 0 0
SHOPIFY INC - CLASS A CL A 82509L107 3,185 74,200 SH   DFND 1 74,200 0 0
SPDR GOLD TRUST GOLD SHS 78463V107 599,933 4,775,012 SH   DFND 1 4,775,012 0 0
STERIS PLC SHS USD G84720104 22,793 311,800 SH   DFND 1 311,800 0 0
ST JUDE MEDICAL INC COM 790849103 7,537 94,500 SH   DFND 1 94,500 0 0
SYNERGY PHARMACEUTICALS INC COM NEW 871639308 133,500 24,228,655 SH   DFND 1 24,228,655 0 0
SYNTHESIS ENERGY SYSTEMS INC COM 871628103 12,100 10,000,000 SH   DFND 1 10,000,000 0 0
TAKE-TWO INTERACTIVE SOFTWRE COM 874054109 43,917 974,200 SH   DFND 1 974,200 0 0
TALEND SA - ADR ADS 874224207 2,637 100,800 SH   DFND 1 100,800 0 0
TEVA PHARMACEUTICAL-SP ADR ADR 881624209 739,698 16,076,900 SH   DFND 1 16,076,900 0 0
TIM PARTICIPACOES SA-ADR SPONSORED ADR 88706P205 70,001 5,719,000 SH   DFND 1 5,719,000 0 0
T-MOBILE US INC COM 872590104 44,571 954,000 SH   DFND 1 954,000 0 0
TOBIRA THERAPEUTICS INC COM 88883P101 42,522 1,070,000 SH   DFND 1 1,070,000 0 0
TRILOGY METALS INC COM 89621C105 6,358 11,612,278 SH   DFND 1 11,612,278 0 0
VALEANT PHARMACEUTICALS INTE COM 91911K102 463,283 18,871,000 SH   DFND 1 18,871,000 0 0
VANDA PHARMACEUTICALS INC COM 921659108 36,192 2,175,000 SH   DFND 1 2,175,000 0 0
VMWARE INC-CLASS A CL A COM 928563402 140,393 1,914,015 SH   DFND 1 1,914,015 0 0
WCI COMMUNITIES INC COM PAR $0.01 92923C807 1,660 70,000 SH   DFND 1 70,000 0 0
WILLIAM LYON HOMES-CL A CL A NEW 552074700 61,635 3,322,666 SH   DFND 1 3,322,666 0 0