The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHAOGEN INC COM 004449104 944 72,500 SH   DFND 1 72,500 0 0
ACTIVISION BLIZZARD INC COM 00507V109 34,954 968,000 SH   DFND 1 968,000 0 0
AGNICO EAGLE MINES LTD COM 008474108 45,385 1,080,600 SH   DFND 1 1,080,600 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 1,539 74,000 SH   DFND 1 74,000 0 0
ALLERGAN PLC SHS G0177J108 746,530 3,554,734 SH   DFND 1 3,554,734 0 0
ALLERGAN PLC SHS G0177J108 45,089 214,700 SH Call DFND 1 214,700 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 18,761 153,341 SH   DFND 1 153,341 0 0
ALPHABET INC CAP STK CL C 02079K107 16,748 21,700 SH   DFND 1 21,700 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 18,720 153,000 SH Put DFND 1 153,000 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 24,470 200,000 SH Call DFND 1 200,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 723 19,300 SH   DFND 1 19,300 0 0
AMERICAN CAP LTD COM 02503Y103 15,516 865,868 SH   DFND 1 865,868 0 0
AMERICAN INTL GROUP INC COM NEW 026874784 314,099 4,809,355 SH   DFND 1 4,809,355 0 0
ANGLOGOLD ASHANTI LTD SPONSORED ADR 035128206 134,343 12,782,400 SH   DFND 1 12,782,400 0 0
AKORN INC COM 009728106 189,626 8,686,500 SH   DFND 1 8,686,500 0 0
ARADIGM CORP COM NO PAR NEW 038505400 308 192,727 SH   DFND 1 192,727 0 0
BANK OF AMERICA CORPORATION *W EXP 01/16/201 060505146 62,322 6,263,526 SH   DFND 1 6,263,526 0 0
BANK OF AMERICA CORPORATION *W EXP 10/28/201 060505153 8,571 8,928,344 SH   DFND 1 8,928,344 0 0
B/E AEROSPACE INC COM 073302101 79,240 1,316,500 SH   DFND 1 1,316,500 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 333 52,600 SH   DFND 1 52,600 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 2,216 350,000 SH Call DFND 1 350,000 0 0
BIOGEN INC COM 09062X103 14,803 52,200 SH   DFND 1 52,200 0 0
BOSTON SCIENTIFIC CORP COM 101137107 6,229 288,000 SH   DFND 1 288,000 0 0
CAESARS ACQUISITION CO CL A 12768T103 177,093 13,117,998 SH   DFND 1 13,117,998 0 0
CAESARS ENTMT CORP COM 127686103 122,552 14,417,900 SH   DFND 1 14,417,900 0 0
CBOE HLDGS INC COM 12503M108 2,838 38,412 SH   DFND 1 38,412 0 0
CELLDEX THERAPEUTICS INC NEW COM 15117B103 251 70,800 SH   DFND 1 70,800 0 0
COBALT INTL ENERGY INC COM 19075F106 37,956 31,111,327 SH   DFND 1 31,111,327 0 0
COBALT INTL ENERGY INC NOTE 2.625%12/0 19075FAA4 17,765 45,260,000 SH   DFND 1 45,260,000 0 0
COBALT INTL ENERGY INC NOTE 3.125% 5/1 19075FAB2 61,384 219,229,000 SH   DFND 1 219,229,000 0 0
CORESITE RLTY CORP COM 21870Q105 10,175 128,200 SH   DFND 1 128,200 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 8,944 1,600,000 SH Put DFND 1 1,600,000 0 0
DELL TECHNOLOGIES INC COM CL V 24703L103 59,923 1,090,104 SH   DFND 1 1,090,104 0 0
DEXCOM INC COM 252131107 17,504 293,200 SH   DFND 1 293,200 0 0
DOLLAR GEN CORP NEW COM 256677105 2,192 29,600 SH   DFND 1 29,600 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 687 174,000 SH   DFND 1 174,000 0 0
EBAY INC COM 278642103 18,485 622,600 SH   DFND 1 622,600 0 0
ENDO INTL PLC SHS G30401106 129,123 7,839,900 SH   DFND 1 7,839,900 0 0
ENZYMOTEC LTD SHS M4059L101 27,549 4,205,980 SH   DFND 1 4,205,980 0 0
ESPERION THERAPEUTICS INC NE COM 29664W105 1,277 102,000 SH   DFND 1 102,000 0 0
ETSY INC COM 29786A106 14,943 1,268,500 SH   DFND 1 1,268,500 0 0
EXTENDED STAY AMER INC UNIT 99/99/9999B 30224P200 455,411 28,628,258 SH   DFND 1 28,628,258 0 0
FACEBOOK INC CL A 30303M102 20,824 181,000 SH   DFND 1 181,000 0 0
FEDEX CORP COM 31428X106 2,048 11,000 SH   DFND 1 11,000 0 0
FELCOR LODGING TR INC COM 31430F101 4,005 500,000 SH   DFND 1 500,000 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 11,399 296,000 SH   DFND 1 296,000 0 0
GOPRO INC CL A 38268T103 3,484 400,000 SH Put DFND 1 400,000 0 0
HARMAN INTL INDS INC COM 413086109 94,908 853,800 SH   DFND 1 853,800 0 0
HCA HOLDINGS INC COM 40412C101 8,261 111,600 SH   DFND 1 111,600 0 0
HEWLETT PACKARD ENTERPRISE C COM 42824C109 68,874 2,976,400 SH   DFND 1 2,976,400 0 0
IAMGOLD CORP COM 450913108 14,876 3,863,912 SH   DFND 1 3,863,912 0 0
INSMED INC COM PAR $.01 457669307 2,715 205,200 SH   DFND 1 205,200 0 0
INTERNATIONAL SEAWAYS INC COM Y41053102 51,683 3,681,122 SH   DFND 1 3,681,122 0 0
INTERNATIONAL TOWER HILL MIN COM 46050R102 12,857 23,058,000 SH   DFND 1 23,058,000 0 0
INTERNATIONAL TOWER HILL MIN COM 46050R102 18,082 32,429,842 SH   DFND 1 32,429,842 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 6,405 10,100 SH   DFND 1 10,100 0 0
KAMADA LTD SHS M6240T109 3,983 730,800 SH   DFND 1 730,800 0 0
LIVANOVA PLC SHS G5509L101 13,941 310,000 SH   DFND 1 310,000 0 0
LIBERTY GLOBAL PLC LILAC SHS CL A G5480U138 110 4,990 SH   DFND 1 4,990 0 0
LOXO ONCOLOGY INC COM 548862101 26,612 828,641 SH   DFND 1 828,641 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 397,408 7,976,872 SH   DFND 1 7,976,872 0 0
MEAD JOHNSON NUTRITION CO COM 582839106 2,179 30,800 SH   DFND 1 30,800 0 0
MERCADOLIBRE INC COM 58733R102 5,996 38,400 SH   DFND 1 38,400 0 0
NEUSTAR INC CL A 64126X201 6,680 200,000 SH   DFND 1 200,000 0 0
MYLAN N V SHS EURO N59465109 785,985 20,602,500 SH   DFND 1 20,602,500 0 0
MYLAN N V SHS EURO N59465109 34,495 904,200 SH Call DFND 1 904,200 0 0
NOVAGOLD RES INC COM NEW 66987E206 101,559 22,271,796 SH   DFND 1 22,271,796 0 0
NOVADAQ TECHNOLOGIES INC COM 66987G102 25 500,000 SH Put DFND 1 500,000 0 0
NXP SEMICONDUCTORS N V COM N6596X109 36,558 373,000 SH   DFND 1 373,000 0 0
OASIS PETE INC NEW COM 674215108 78,536 5,187,300 SH   DFND 1 5,187,300 0 0
OFFICE DEPOT INC COM 676220106 68,983 15,261,657 SH   DFND 1 15,261,657 0 0
OVERSEAS SHIPHOLDING GROUP I CL A NEW 69036R863 274 71,602 SH   DFND 1 71,602 0 0
PANDORA MEDIA INC COM 698354107 12,910 990,000 SH Put DFND 1 990,000 0 0
PFIZER INC COM 717081103 11,439 352,200 SH   DFND 1 352,200 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 482 15,690 SH   DFND 1 15,690 0 0
RANDGOLD RES LTD ADR 752344309 38,170 500,000 SH   DFND 1 500,000 0 0
REALOGY HLDGS CORP COM 75605Y106 123,118 4,785,000 SH   DFND 1 4,785,000 0 0
RETROPHIN INC COM 761299106 1,041 55,000 SH   DFND 1 55,000 0 0
REYNOLDS AMERICAN INC COM 761713106 5,940 106,000 SH   DFND 1 106,000 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 923 387,697 SH   DFND 1 387,697 0 0
SANDRIDGE ENERGY INC COM NEW 80007P869 5,771 245,046 SH   DFND 1 245,046 0 0
SANDRIDGE ENERGY INC NOTE 10/0 80007PBC2 9,972 7,906,627 SH   DFND 1 7,906,627 0 0
SANOFI SPONSORED ADR 80105N105 10,231 253,000 SH   DFND 1 253,000 0 0
SHIRE PLC SPONSORED ADR 82481R106 716,635 4,206,100 SH   DFND 1 4,206,100 0 0
SHIRE PLC SPONSORED ADR 82481R106 27,261 160,000 SH Call DFND 1 160,000 0 0
SHOPIFY INC CL A 82509L107 1,745 40,700 SH   DFND 1 40,700 0 0
SPDR GOLD TRUST GOLD SHS 78463V107 477,869 4,359,722 SH   DFND 1 4,359,722 0 0
STERIS PLC SHS USD G84720104 21,127 313,500 SH   DFND 1 313,500 0 0
SYNERGY PHARMACEUTICALS DEL COM NEW 871639308 146,700 24,088,655 SH   DFND 1 24,088,655 0 0
SYNTHESIS ENERGY SYS INC COM 871628103 10,000 10,000,000 SH   DFND 1 10,000,000 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 47,708 967,900 SH   DFND 1 967,900 0 0
TEVA PHARMACEUTICAL INDS LTD ADR 881624209 577,310 15,925,800 SH   DFND 1 15,925,800 0 0
TIM PARTICIPACOES S A SPONSORED ADR 88706P205 66,967 5,675,200 SH   DFND 1 5,675,200 0 0
TIME INC NEW COM 887228104 17,711 992,200 SH   DFND 1 992,200 0 0
TIME WARNER INC COM NEW 887317303 275,680 2,855,900 SH   DFND 1 2,855,900 0 0
TRILOGY METALS INC NEW COM 89621C105 5,884 11,603,178 SH   DFND 1 11,603,178 0 0
VALEANT PHARMACEUTICALS INTL COM 91911K102 281,463 19,384,500 SH   DFND 1 19,384,500 0 0
VMWARE INC CL A COM 928563402 78,116 992,200 SH   DFND 1 992,200 0 0
WCI CMNTYS INC COM PAR $0.01 92923C807 1,642 70,000 SH   DFND 1 70,000 0 0
WENDYS CO COM 95058W100 16,900 1,250,000 SH Put DFND 1 1,250,000 0 0
WHITEWAVE FOODS CO COM 966244105 37,608 676,400 SH   DFND 1 676,400 0 0
LYON WILLIAM HOMES CL A NEW 552074700 63,230 3,322,666 SH   DFND 1 3,322,666 0 0
WORKDAY INC CL A 98138H101 11,493 173,900 SH   DFND 1 173,900 0 0