The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Achillion Pharmaceuticals In | COM | 00448Q201 | 1,182 | 286,285 | SH | SOLE | 1 | 286,285 | 0 | 0 | |
| Agenus Inc | COM NEW | 00847G705 | 17,346 | 4,210,264 | SH | SOLE | 1 | 4,210,264 | 0 | 0 | |
| Alnylam Pharmaceuticals Inc | COM | 02043Q107 | 29,548 | 789,208 | SH | SOLE | 1 | 789,208 | 0 | 0 | |
| Atara Biotherapeutics Inc | COM | 046513107 | 5,291 | 372,624 | SH | SOLE | 1 | 372,624 | 0 | 0 | |
| Audentes Therapeutics Inc | COM | 05070R104 | 365 | 20,000 | SH | SOLE | 1 | 20,000 | 0 | 0 | |
| Avexis Inc | COM | 05366U100 | 40,525 | 849,043 | SH | SOLE | 1 | 849,043 | 0 | 0 | |
| Biocryst Pharmaceuticals | COM | 09058V103 | 25,819 | 4,078,895 | SH | SOLE | 1 | 4,078,895 | 0 | 0 | |
| Biopharmx Corp | COM | 09072X101 | 476 | 1,273,128 | SH | SOLE | 1 | 1,273,128 | 0 | 0 | |
| bluebird bio Inc | COM | 09609G100 | 7,563 | 122,576 | SH | SOLE | 1 | 122,576 | 0 | 0 | |
| Bristol Myers Squibb Co | COM | 110122108 | 33,070 | 565,888 | SH | SOLE | 1 | 565,888 | 0 | 0 | |
| Celldex Therapeutics Inc New | COM | 15117B103 | 848 | 239,662 | SH | SOLE | 1 | 239,662 | 0 | 0 | |
| Corium Intl Inc | COM | 21887L107 | 4,470 | 1,101,045 | SH | SOLE | 1 | 1,101,045 | 0 | 0 | |
| Dicerna Pharmaceuticals Inc | COM | 253031108 | 5,884 | 2,043,216 | SH | SOLE | 1 | 2,043,216 | 0 | 0 | |
| Global Blood Therapeutics In | COM | 37890U108 | 375 | 25,963 | SH | SOLE | 1 | 25,963 | 0 | 0 | |
| Incyte Corp | COM | 45337C102 | 8,699 | 86,757 | SH | SOLE | 1 | 86,757 | 0 | 0 | |
| Invuity Inc | COM NEW | 46187J205 | 2,616 | 454,900 | SH | SOLE | 1 | 454,900 | 0 | 0 | |
| La Jolla Pharmaceutical Co | COM PAR $.0001 2 | 503459604 | 19,038 | 1,086,037 | SH | SOLE | 1 | 1,086,037 | 0 | 0 | |
| Masimo Corp | COM | 574795100 | 5,453 | 80,900 | SH | SOLE | 1 | 80,900 | 0 | 0 | |
| Medicines Co | COM | 584688105 | 12,702 | 374,263 | SH | SOLE | 1 | 374,263 | 0 | 0 | |
| Mirati Therapeutics Inc | COM | 60468T105 | 616 | 129,697 | SH | SOLE | 1 | 129,697 | 0 | 0 | |
| Mannkind Corp | COM | 56400P201 | 279 | 438,500 | SH | Put | SOLE | 1 | 438,500 | 0 | 0 |
| Natera Inc | COM | 632307104 | 371 | 31,693 | SH | SOLE | 1 | 31,693 | 0 | 0 | |
| Nivalis Therapeutics Inc | COM | 65481J109 | 67 | 30,000 | SH | SOLE | 1 | 30,000 | 0 | 0 | |
| Omeros Corp | COM | 682143102 | 2,570 | 259,039 | SH | SOLE | 1 | 259,039 | 0 | 0 | |
| Oxford Immunotec Global PLC | ORD SHS | G6855A103 | 8,122 | 543,287 | SH | SOLE | 1 | 543,287 | 0 | 0 | |
| PTC Therapeutics Inc | COM | 69366J200 | 10,879 | 997,166 | SH | SOLE | 1 | 997,166 | 0 | 0 | |
| Regenxbio Inc | COM | 75901B107 | 4,448 | 239,789 | SH | SOLE | 1 | 239,789 | 0 | 0 | |
| Sensus Heatlhcare Inc | COM | 81728J109 | 645 | 122,803 | SH | SOLE | 1 | 122,803 | 0 | 0 | |
| Sensus Heatlhcare Inc | WARRANTS EXP 12/31/2019 | 81728J117 | 78 | 155,000 | SH | SOLE | 1 | 155,000 | 0 | 0 | |
| Tactile Sys Technology Inc | COM | 87357P100 | 4,082 | 248,762 | SH | SOLE | 1 | 248,762 | 0 | 0 | |
| United States Oil Fund LP | UNITS | 91232N108 | 7,911 | 675,000 | SH | SOLE | 1 | 675,000 | 0 | 0 | |
| Viveve Med Inc | COM NEW | 92852W204 | 4,324 | 839,666 | SH | SOLE | 1 | 839,666 | 0 | 0 | |