The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABEONA THERAPEUTICS INC COM 00289Y107 1,940 400,000 SH   SOLE   400,000 0 0
ACHAOGEN INC COM 004449104 1,041 80,000 SH   SOLE   80,000 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 4,817 285,000 SH   SOLE   285,000 0 0
AEVI GENOMIC MEDICINE INC COM 00835P105 7,770 1,500,000 SH   SOLE   1,500,000 0 0
AGIOS PHARMACEUTICALS COM 00847X104 5,425 130,000 SH   SOLE   130,000 0 0
AGILE THERAPEUTICS INC COM 00847L100 85 15,000 SH   SOLE   15,000 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 5,118 310,000 SH   SOLE   310,000 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 12,440 1,000,000 SH   SOLE   1,000,000 0 0
AXOGEN INC COM 05463X106 17,730 1,970,000 SH   SOLE   1,970,000 0 0
BIOLINERX LTD SPONSORED ADR 09071M106 230 250,000 SH   SOLE   250,000 0 0
BLUEPRINT MEDICINES COM 09627Y109 24,684 880,000 SH   SOLE   880,000 0 0
CARA THERAPEUTICS COM 140755109 4,413 475,000 SH   SOLE   475,000 0 0
CHIMERIX INC COM 16934W106 5,382 1,170,000 SH   SOLE   1,170,000 0 0
CLEARSIDE BIOMEDICAL INC COM 185063104 2,414 270,000 SH   SOLE   270,000 0 0
CODEXIS INC COM 192005106 5,382 1,170,000 SH   SOLE   1,170,000 0 0
CORIUM INTERNATIONAL INC COM 21887L107 1,543 380,000 SH   SOLE   380,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 1,868 170,000 SH   SOLE   170,000 0 0
EAGLE PHARMACEUTICALS INC COM 269796108 3,967 50,000 SH   SOLE   50,000 0 0
EDGE THERAPEUTICS INC COM 279870109 3,500 280,000 SH   SOLE   280,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 3,015 90,000 SH   SOLE   90,000 0 0
FIBROGEN INC COM 31572Q808 7,062 330,000 SH   SOLE   330,000 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 5,495 495,000 SH   SOLE   495,000 0 0
IMPRIMIS PHARMACEUTICALS INC COM NEW 45323A201 1,800 720,000 SH   SOLE   720,000 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 2,085 300,000 SH   SOLE   300,000 0 0
LOXO ONCOLOGY COM 548862101 4,014 125,000 SH   SOLE   125,000 0 0
MACROGENICS INC COM 556099109 3,475 170,000 SH   SOLE   170,000 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 4,967 330,000 SH   SOLE   330,000 0 0
NEURODERM LTD ORD SHS M74231107 1,731 115,000 SH   SOLE   115,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100 783 93,600 SH   SOLE   93,600 0 0
OMEROS CORP COM 682143102 2,632 265,300 SH   SOLE   265,300 0 0
PROTALIX BIOTHERAPEUTICS INC COM 74365AAB7 859 1,930,000 SH   SOLE   1,930,000 0 0
PROTEOSTASIS THERAPEUTICS INC COM 74373B109 1,839 150,000 SH   SOLE   150,000 0 0
PROTHENA CORP PLC SHS G72800108 4,058 82,500 SH   SOLE   82,500 0 0
SAGE THERAPEUTICS INC COM 78667J108 1,787 35,000 SH   SOLE   35,000 0 0
SANGAMO BIOSCIENCES INC COM 800677106 1,220 400,000 SH   SOLE   400,000 0 0
STRONGBRIDGE BIOPHARMA PLC ORD SHS G85347105 2,784 1,160,000 SH   SOLE   1,160,000 0 0
THERAVANCE BIOPHARMA INC ORD SHS G8807B106 5,043 158,200 SH   SOLE   158,200 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 622 110,000 SH   SOLE   110,000 0 0
WAFERGEN BIO-SYSTEMS INC COM 93041P506 1,578 320,000 SH   SOLE   320,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 3,119 405,000 SH   SOLE   405,000 0 0