The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AAC HLDGS INC COM 000307108 384 45,000 SH   DFND 1 0 0 45,000
ABBOTT LABS COM 002824100 18,008 405,500 SH   DFND 1 0 0 405,500
ABBVIE INC COM 00287Y109 6,692 102,701 SH   DFND 1 0 0 102,701
ABIOMED INC COM 003654100 7,972 63,670 SH   DFND 1 0 0 63,670
ACADIA PHARMACEUTICALS INC COM 004225108 1,547 45,000 SH   DFND 1 0 0 45,000
ACHILLION PHARMACEUTICALS IN COM 00448Q201 417 99,000 SH   DFND 1 0 0 99,000
AETNA INC NEW COM 00817Y108 5,434 42,600 SH   DFND 1 0 0 42,600
AGIOS PHARMACEUTICALS INC COM 00847X104 2,628 45,000 SH   DFND 1 0 0 45,000
AKORN INC COM 009728106 11,910 494,600 SH   DFND 1 0 0 494,600
ALDER BIOPHARMACEUTICALS INC COM 014339105 686 33,000 SH   DFND 1 0 0 33,000
ALERE INC COM 01449J105 5,775 145,363 SH   DFND 1 0 0 145,363
ALEXION PHARMACEUTICALS INC COM 015351109 8,608 71,000 SH   DFND 1 0 0 71,000
ALIGN TECHNOLOGY INC COM 016255101 15,624 136,200 SH   DFND 1 0 0 136,200
ALKERMES PLC SHS G01767105 2,311 39,500 SH   DFND 1 0 0 39,500
ALLERGAN PLC SHS G0177J108 6,929 29,000 SH   DFND 1 0 0 29,000
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 7,272 141,900 SH   DFND 1 0 0 141,900
AMERISOURCEBERGEN CORP COM 03073E105 9,036 102,099 SH   DFND 1 0 0 102,099
AMGEN INC COM 031162100 25,505 155,450 SH   DFND 1 0 0 155,450
ANGIODYNAMICS INC COM 03475V101 1,765 101,700 SH   DFND 1 0 0 101,700
ANTHEM INC COM 036752103 18,268 110,460 SH   DFND 1 0 0 110,460
AURIS MED HLDG AG COM H03579101 1,996 2,169,625 SH   DFND 1 0 0 2,169,625
BARD C R INC COM 067383109 12,037 48,430 SH   DFND 1 0 0 48,430
BAXTER INTL INC COM 071813109 9,853 190,000 SH   DFND 1 0 0 190,000
BECTON DICKINSON & CO COM 075887109 5,503 30,000 SH   DFND 1 0 0 30,000
BIOGEN INC COM 09062X103 14,628 53,500 SH   DFND 1 0 0 53,500
BIOMARIN PHARMACEUTICAL INC COM 09061G101 5,706 65,000 SH   DFND 1 0 0 65,000
BIOVERATIV INC COM 09075E100 1,239 22,750 SH   DFND 1 0 0 22,750
BLUEBIRD BIO INC COM 09609G100 2,636 29,000 SH   DFND 1 0 0 29,000
BOSTON SCIENTIFIC CORP COM 101137107 14,226 572,000 SH   DFND 1 0 0 572,000
BRISTOL MYERS SQUIBB CO COM 110122108 1,251 23,000 SH   DFND 1 0 0 23,000
CARDINAL HEALTH INC COM 14149Y108 1,631 20,000 SH   DFND 1 0 0 20,000
CELGENE CORP COM 151020104 31,279 251,380 SH   DFND 1 0 0 251,380
CELLDEX THERAPEUTICS INC NEW COM 15117B103 578 160,000 SH   DFND 1 0 0 160,000
CEMPRA INC COM 15130J109 619 165,000 SH   DFND 1 0 0 165,000
CENTENE CORP DEL COM 15135B101 20,903 293,340 SH   DFND 1 0 0 293,340
CERNER CORP COM 156782104 4,384 74,500 SH   DFND 1 0 0 74,500
CERUS CORP COM 157085101 134 30,000 SH   DFND 1 0 0 30,000
CIGNA CORPORATION COM 125509109 4,834 33,000 SH   DFND 1 0 0 33,000
CLOVIS ONCOLOGY INC COM 189464100 1,178 18,500 SH   DFND 1 0 0 18,500
COHERUS BIOSCIENCES INC COM 19249H103 3,701 175,000 SH   DFND 1 0 0 175,000
COOPER COS INC COM 216648402 3,998 20,000 SH   DFND 1 0 0 20,000
CVS HEALTH CORP COM 126650100 2,622 33,400 SH   DFND 1 0 0 33,400
DANAHER CORP DEL COM 235851102 9,750 114,000 SH   DFND 1 0 0 114,000
DAVITA INC COM 23918K108 680 10,000 SH   DFND 1 0 0 10,000
DENTSPLY SIRONA INC COM 24906P109 2,810 45,000 SH   DFND 1 0 0 45,000
DEXCOM INC COM 252131107 3,059 36,100 SH   DFND 1 0 0 36,100
EAGLE PHARMACEUTICALS INC COM 269796108 5,615 67,700 SH   DFND 1 0 0 67,700
EDWARDS LIFESCIENCES CORP COM 28176E108 11,759 125,000 SH   DFND 1 0 0 125,000
ELI LILLY & CO COM 532457108 11,052 131,400 SH   DFND 1 0 0 131,400
ENDO INTL PLC SHS G30401106 1,283 115,000 SH   DFND 1 0 0 115,000
ENVISION HEALTHCARE HLDGS INC COM 29413U103 799 13,026 SH   DFND 1 0 0 13,026
ESPERION THERAPEUTICS INC NEW COM 29664W105 1,130 32,000 SH   DFND 1 0 0 32,000
EXELIXIS INC COM 30161Q104 1,127 52,000 SH   DFND 1 0 0 52,000
EXPRESS SCRIPTS HLDG CO COM 30219G108 3,263 49,500 SH   DFND 1 0 0 49,500
GENMARK DIAGNOSTICS INC. COM 372309104 4,008 312,666 SH   DFND 1 0 0 312,666
GILEAD SCIENCES INC COM 375558103 19,726 290,428 SH   DFND 1 0 0 290,428
GLAUKOS CORP COM 377322102 1,026 20,000 SH   DFND 1 0 0 20,000
GLOBUS MED INC CL A 379577208 1,185 40,000 SH   DFND 1 0 0 40,000
GW PHARMACEUTICALS PLC ADS 36197T103 726 6,000 SH   DFND 1 0 0 6,000
HALOZYME THERAPEUTICS INC COM 40637H109 3,499 270,000 SH   DFND 1 0 0 270,000
HCA HOLDINGS INC COM 40412C101 1,896 21,300 SH   DFND 1 0 0 21,300
HEALTHCARE SVCS GRP INC COM 421906108 711 16,500 SH   DFND 1 0 0 16,500
HILL-ROM HOLDINGS INC COM 431475102 7,221 102,274 SH   DFND 1 0 0 102,274
HOLOGIC INC COM 436440101 14,573 342,490 SH   DFND 1 0 0 342,490
HORIZON PHARMA PLC SHS G4617B105 7,372 498,765 SH   DFND 1 0 0 498,765
HUMANA INC COM 444859102 3,917 19,000 SH   DFND 1 0 0 19,000
ILLUMINA INC COM 452327109 16,884 98,944 SH   DFND 1 0 0 98,944
INCYTE CORP COM 45337C102 24,990 186,950 SH   DFND 1 0 0 186,950
INOVIO PHARMACEUTICALS INC COM 45773H201 953 144,000 SH   DFND 1 0 0 144,000
INSULET CORP COM 45784P101 646 15,000 SH   DFND 1 0 0 15,000
INTEGRA LIFESCIENCES HLDGS C COM 457985208 632 15,000 SH   DFND 1 0 0 15,000
INTERCEPT PHARMACEUTICALS IN COM 45845P108 961 8,500 SH   DFND 1 0 0 8,500
INTERSECT ENT INC COM 46071F103 1,715 100,000 SH   DFND 1 0 0 100,000
INTUITIVE SURGICAL INC COM 46120E602 16,805 21,925 SH   DFND 1 0 0 21,925
IONIS PHARMACEUTICALS INC COM 462222100 8,251 205,253 SH   DFND 1 0 0 205,253
ISHARES TR NASDQ BIOTEC ETF 464287556 3,519 12,000 SH   DFND 1 0 0 12,000
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 15,471 106,600 SH   DFND 1 0 0 106,600
JOHNSON & JOHNSON COM 478160104 3,923 31,500 SH   DFND 1 0 0 31,500
JUNO THERAPEUTICS INC COM 48205A109 821 37,000 SH   DFND 1 0 0 37,000
KITE PHARMA INC COM 49803L109 1,099 14,000 SH   DFND 1 0 0 14,000
LABORATORY CORP AMER HLDGS COM 50540R409 1,865 13,000 SH   DFND 1 0 0 13,000
LIGAND PHARAMCEUTICALS INC COM 53220K504 12,546 118,540 SH   DFND 1 0 0 118,540
LIVANOVA PLC SHS G5509L101 3,146 64,189 SH   DFND 1 0 0 64,189
MACROGENICS INC COM 556099109 5,666 304,597 SH   DFND 1 0 0 304,597
MALLINCKRODT PUB LTD CO SHS G5785G107 8,144 182,725 SH   DFND 1 0 0 182,725
MASIMO COM 574795100 2,145 23,000 SH   DFND 1 0 0 23,000
MCKESSON CORP COM 58155Q103 3,558 24,000 SH   DFND 1 0 0 24,000
MEDICINES CO COM 584688105 1,051 21,500 SH   DFND 1 0 0 21,500
MEDTRONIC PLC SHS G5960L103 19,536 242,500 SH   DFND 1 0 0 242,500
MERCK & CO INC COM 58933Y105 1,747 27,500 SH   DFND 1 0 0 27,500
MOLINA HEALTHCARE INC COM 60855R100 752 16,500 SH   DFND 1 0 0 16,500
MYLAN N V SHS EURO N59465109 10,028 257,200 SH   DFND 1 0 0 257,200
MYRIAD GENETICS INC COM 62855J104 250 13,000 SH   DFND 1 0 0 13,000
NEKTAR THERAPEUTICS COM 640268108 4,036 172,000 SH   DFND 1 0 0 172,000
NEUROCRINE BIOSCIENCES INC COM 64125C109 2,944 68,000 SH   DFND 1 0 0 68,000
NEVRO CORP COM 64157F103 815 8,700 SH   DFND 1 0 0 8,700
NOVADAQ TECHNOLOGIES INC COM 66987G102 1,169 150,000 SH   DFND 1 0 0 150,000
NOVAVAX INC COM 670002104 416 325,000 SH   DFND 1 0 0 325,000
NUVASIVE INC COM 670704105 2,338 31,304 SH   DFND 1 0 0 31,304
OBALON THERAPEUTICS INC COM 67424L100 428 40,000 SH   DFND 1 0 0 40,000
PENUMBRA INC COM 70975L107 417 5,000 SH   DFND 1 0 0 5,000
PERRIGO CO PLC SHS G97822103 6,268 94,411 SH   DFND 1 0 0 94,411
PFIZER INC COM 717081103 1,711 50,000 SH   DFND 1 0 0 50,000
PORTOLA PHARMACEUTICALS INC COM 737010108 1,411 36,000 SH   DFND 1 0 0 36,000
PROTHENA CORP PLC SHS G72800108 2,287 41,000 SH   DFND 1 0 0 41,000
QIAGEN NV REG SHS N72482107 2,302 79,444 SH   DFND 1 0 0 79,444
QUOTIENT LTD SHS G73268107 769 110,000 SH   DFND 1 0 0 110,000
RADIUS HEALTH INC COM 750469207 1,411 36,500 SH   DFND 1 0 0 36,500
REGENERON PHARMACEUTICALS COM 75886F107 11,354 29,300 SH   DFND 1 0 0 29,300
RESMED INC COM 761152107 576 8,000 SH   DFND 1 0 0 8,000
REWALK ROBOTICS LTD SHS M8216Q101 420 200,000 SH   DFND 1 0 0 200,000
SEATTLE GENETICS INC COM 812578102 2,452 39,000 SH   DFND 1 0 0 39,000
SHIRE PLC SPONSORED ADR 82481R106 11,447 65,700 SH   DFND 1 0 0 65,700
STRYKER CORP COM 863667101 16,136 122,570 SH   DFND 1 0 0 122,570
SURGERY PARTNERS INC COM 86881A100 205 10,500 SH   DFND 1 0 0 10,500
TELADOC INC COM 87918A105 500 20,000 SH   DFND 1 0 0 20,000
TELEFLEX INC COM 879369106 1,259 6,500 SH   DFND 1 0 0 6,500
TENET HEALTHCARE CORP COM 88033G407 5,766 325,546 SH   DFND 1 0 0 325,546
TESARO INC COM 881569107 2,462 16,000 SH   DFND 1 0 0 16,000
TEVA PHARMACEUTICAL INDS LTD ADR 881624209 11,751 366,172 SH   DFND 1 0 0 366,172
THERAVANCE BIOPHARMA INC COM G8807B106 531 14,428 SH   DFND 1 0 0 14,428
THERMO FISHER SCIENTIFIC INC COM 883556102 1,997 13,000 SH   DFND 1 0 0 13,000
ULTRAGENYX PHARMACEUTICAL INC COM 90400D108 2,847 42,000 SH   DFND 1 0 0 42,000
UNITED THERAPEUTICS CORP DEL COM 91307C102 1,056 7,800 SH   DFND 1 0 0 7,800
UNITEDHEALTH GROUP INC COM 91324P102 20,327 123,940 SH   DFND 1 0 0 123,940
VARIAN MED SYS INC COM 92220P105 638 7,000 SH   DFND 1 0 0 7,000
VERTEX PHARMACEUTICALS INC COM 92532F100 8,310 76,000 SH   DFND 1 0 0 76,000
WALGREENS BOOTS ALLIANCE INC COM 931427108 13,322 160,409 SH   DFND 1 0 0 160,409
WEBMD HEALTH CORP COM 94770V102 390 7,400 SH   DFND 1 0 0 7,400
WRIGHT MED GROUP NV ORD SHS 0.03 PAR N96617118 8,983 288,663 SH   DFND 1 0 0 288,663
ZELTIQ AESTHETICS INC COM 98933Q108 1,223 22,000 SH   DFND 1 0 0 22,000
ZIMMER BIOMET HLDGS INC COM 98956P102 10,746 88,000 SH   DFND 1 0 0 88,000