The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABEONA THERAPEUTICS INC COM 00289Y107 1,375 275,000 SH   SOLE   275,000 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 5,075 290,000 SH   SOLE   290,000 0 0
AEVI GENOMIC MEDICINE INC COM 00835P105 1,990 1,070,000 SH   SOLE   1,070,000 0 0
AGIOS PHARMACEUTICALS COM 00847X104 7,592 130,000 SH   SOLE   130,000 0 0
ALBIREO PHARMA INC COM 01345P106 876 36,500 SH   SOLE   36,500 0 0
AQUINOX PHARMACEUTICALS INC COM 03842B101 1,418 85,000 SH   SOLE   85,000 0 0
ARQULE INC COM 04269E107 593 560,000 SH   SOLE   560,000 0 0
AXOGEN INC COM 05463X106 20,586 1,970,000 SH   SOLE   1,970,000 0 0
BIOLINERX LTD SPONSORED ADR 09071M106 240 250,000 SH   SOLE   250,000 0 0
BLUEPRINT MEDICINES COM 09627Y109 35,191 880,000 SH   SOLE   880,000 0 0
CARA THERAPEUTICS COM 140755109 7,080 385,000 SH   SOLE   385,000 0 0
CHIMERIX INC COM 16934W106 7,751 1,215,000 SH   SOLE   1,215,000 0 0
CIDARA THERAPEUTICS INC COM 171757107 955 122,500 SH   SOLE   122,500 0 0
CODEXIS INC COM 192005106 5,616 1,170,000 SH   SOLE   1,170,000 0 0
CORIUM INTERNATIONAL INC COM 21887L107 677 162,000 SH   SOLE   162,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 5,871 340,000 SH   SOLE   340,000 0 0
EAGLE PHARMACEUTICALS INC COM 269796108 4,147 50,000 SH   SOLE   50,000 0 0
EDGE THERAPEUTICS INC COM 279870109 2,550 280,000 SH   SOLE   280,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 3,080 100,000 SH   SOLE   100,000 0 0
FIBROGEN INC COM 31572Q808 8,134 330,000 SH   SOLE   330,000 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 2,475 500,000 SH   SOLE   500,000 0 0
IMMUNOMEDICS INC COM 452907108 6,211 960,000 SH   SOLE   960,000 0 0
IMPRIMIS PHARMACEUTICALS INC COM NEW 45323A201 3,588 860,500 SH   SOLE   860,500 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 770 60,000 SH   SOLE   60,000 0 0
LION BIOTECHNOLOGIES INC COM 53619R102 1,713 230,000 SH   SOLE   230,000 0 0
LOXO ONCOLOGY COM 548862101 5,470 130,000 SH   SOLE   130,000 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 5,874 440,000 SH   SOLE   440,000 0 0
NEURODERM LTD ORD SHS M74231107 3,186 120,000 SH   SOLE   120,000 0 0
NOVELION THERAPEUTICS INC COM NEW 67001K202 7,840 730,000 SH   SOLE   730,000 0 0
OCULAR THERAPEUTIX INC COM 67576A100 5,104 550,000 SH   SOLE   550,000 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 1,959 50,000 SH   SOLE   50,000 0 0
PROTALIX BIOTHERAPEUTICS INC COM 74365AAB7 2,624 1,930,000 SH   SOLE   1,930,000 0 0
PROTHENA CORP PLC SHS G72800108 4,859 87,100 SH   SOLE   87,100 0 0
SAGE THERAPEUTICS INC COM 78667J108 3,198 45,000 SH   SOLE   45,000 0 0
SANGAMO BIOSCIENCES INC COM 800677106 3,021 581,000 SH   SOLE   581,000 0 0
STRONGBRIDGE BIOPHARMA PLC COM G85347105 5,605 1,180,000 SH   SOLE   1,180,000 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 2,255 550,000 SH   SOLE   550,000 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 400 25,149 SH   SOLE   25,149 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 6,627 180,000 SH   SOLE   180,000 0 0
TONIX PHARMACEUTICALS HOLDING COM NEW 890260201 1,097 235,000 SH   SOLE   235,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 2,153 78,300 SH   SOLE   78,300 0 0
XENON PHARMACEUTICALS INC COM 98420N105 1,440 360,000 SH   SOLE   360,000 0 0
XOMA CORP DEL COM NEW 98419J206 287 40,400 SH   SOLE   40,400 0 0
ZOSANO PHARMA CORP COM 98979H103 2,375 1,250,000 SH   SOLE   1,250,000 0 0