The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Agenus Inc COM NEW 00847G705 16,007 4,245,882 SH   SOLE 1 4,245,882 0 0
Alnylam Pharmaceuticals Inc COM 02043Q107 55,991 1,092,516 SH   SOLE 1 1,092,516 0 0
Arbutus Biopharma Corp COM 03879J100 4,701 1,446,587 SH   SOLE 1 1,446,587 0 0
Atara Biotherapeutics Inc COM 046513107 18,674 908,733 SH   SOLE 1 908,733 0 0
Avexis Inc COM 05366U100 47,392 623,330 SH   SOLE 1 623,330 0 0
BioCryst Pharmaceuticals Inc COM 09058V103 29,048 3,458,120 SH   SOLE 1 3,458,120 0 0
Biopharmx Corp COM 09072X101 648 1,283,951 SH   SOLE 1 1,283,951 0 0
bluebird bio Inc COM 09609G100 9,419 103,617 SH   SOLE 1 103,617 0 0
Bristol-Myers Squibb Co COM 110122108 31,034 570,692 SH   SOLE 1 570,692 0 0
Celldex Therapeutics Inc COM 15117B103 873 241,699 SH   SOLE 1 241,699 0 0
Corium International Inc COM 21887L107 6,057 1,448,991 SH   SOLE 1 1,448,991 0 0
Dicerna Pharmaceuticals Inc COM 253031108 7,014 2,062,991 SH   SOLE 1 2,062,991 0 0
Global Blood Therapeutics Inc COM 37890U108 965 26,183 SH   SOLE 1 26,183 0 0
Incyte Corp COM 45337C102 11,026 82,490 SH   SOLE 1 82,490 0 0
Invuity Inc COM NEW 46187J205 3,738 470,167 SH   SOLE 1 470,167 0 0
La Jolla Pharmaceutical Co COM PAR $.0001 2 503459604 30,714 1,028,929 SH   SOLE 1 1,028,929 0 0
Masimo Corp COM 574795100 7,545 80,900 SH   SOLE 1 80,900 0 0
Medicines Co COM 584688105 28,004 572,689 SH   SOLE 1 572,689 0 0
Natera Inc COM 632307104 281 31,693 SH   SOLE 1 31,693 0 0
OraSure Technologies Inc COM 68554V108 7,321 566,230 SH   SOLE 1 566,230 0 0
Oxford Immunotec Global PLC ORD SHS G6855A103 9,494 612,903 SH   SOLE 1 612,903 0 0
PTC Therapeutics Inc COM 69366J200 12,848 1,305,643 SH   SOLE 1 1,305,643 0 0
Regenxbio Inc COM 75901B107 23,479 1,216,505 SH   SOLE 1 1,216,505 0 0
Sensus Healthcare Inc COM 81728J109 397 90,404 SH   SOLE 1 90,404 0 0
Tactile Systems Technology Inc COM 87357P100 5,455 287,876 SH   SOLE 1 287,876 0 0
Viewray Inc COM 92672L107 4,388 515,612 SH   SOLE 1 515,612 0 0
Viveve Medical Inc COM NEW 92852W204 7,253 1,145,736 SH   SOLE 1 1,145,736 0 0
Sensus Heatlhcare Inc *W EXP 06/08/201 81728J117 136 155,000 SH   SOLE 1 155,000 0 0