The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Accenture plc COM G1151C101 119 965 SH   SOLE   965 0 0
Advansix COM 00773T101 9 286 SH   SOLE   286 0 0
Advaxis COM 007624208 475 73,178 SH   SOLE   73,178 0 0
AFLAC Inc. COM 001055102 1,286 16,551 SH   SOLE   16,551 0 0
Alaska Air Group Inc. COM 011659109 1,780 19,832 SH   SOLE   19,832 0 0
Amazon.com Inc. COM 023135106 131 135 SH   SOLE   135 0 0
Amgen Inc. COM 031162100 20 115 SH   SOLE   115 0 0
Altria Group, Inc. COM 718154107 651 8,743 SH   SOLE   8,743 0 0
Amyris COM 03236M101 977 307,254 SH   SOLE   307,254 0 0
Apple Computing COM 037833100 3,023 20,992 SH   SOLE   20,992 0 0
Applied Materials COM 038222105 102 2,462 SH   SOLE   2,462 0 0
ASML Holding N V ADR COM N07059111 37 284 SH   SOLE   284 0 0
BeyondSpring Inc COM G10830100 914 21,322 SH   SOLE   21,322 0 0
Cameco COM 13321L108 19 2,100 SH   SOLE   2,100 0 0
Catalyst Pharmaceuticals COM 14888U101 665 241,078 SH   SOLE   241,078 0 0
CBS Corp. COM 124857103 2,868 44,971 SH   SOLE   44,971 0 0
Celgene Corp. COM 151020104 1,811 13,945 SH   SOLE   13,945 0 0
Church and Dwight Co. Inc. COM 171340102 7 140 SH   SOLE   140 0 0
Colgate-Palmolive Co. COM 194162103 21 288 SH   SOLE   288 0 0
Corcept Therapeutics COM 218352102 1,645 139,397 SH   SOLE   139,397 0 0
Facebook, Inc. COM 30303M102 77 509 SH   SOLE   509 0 0
Fuelnation, Inc. COM 359528205 0 251,150 SH   SOLE   251,150 0 0
General Electric Company COM 369604103 19 716 SH   SOLE   716 0 0
Google Inc. COM 38259P706 164 176 SH   SOLE   176 0 0
Google Inc. COM 38259P508 160 176 SH   SOLE   176 0 0
Hawaiian Holdings COM 419879101 13 275 SH   SOLE   275 0 0
Helen of Troy Limited COM G4388N106 713 7,572 SH   SOLE   7,572 0 0
Honeywell International Inc. COM 438516106 835 6,266 SH   SOLE   6,266 0 0
Inovio Pharmaceuticals COM 45773H102 688 87,810 SH   SOLE   87,810 0 0
Ionis Pharmaceuticals COM 462222100 4,168 81,937 SH   SOLE   81,937 0 0
JetBlue Airways Corp. COM 477143101 1,045 45,764 SH   SOLE   45,764 0 0
JPMorgan Chase and Co. COM 46625H100 182 1,994 SH   SOLE   1,994 0 0
Johnson and Johnson COM 478160104 7 50 SH   SOLE   50 0 0
Kraft Heinz Company COM 50076Q106 32 376 SH   SOLE   376 0 0
Mondelez International, Inc. COM 609207105 26 596 SH   SOLE   596 0 0
Monroe Muffler Brake Inc. COM 610236101 15 365 SH   SOLE   365 0 0
Mymetics Corp COM 62856A102 5 167,649 SH   SOLE   167,649 0 0
Nanoco Group plc COM 0B01JLR99 2,202 3,863,365 SH   SOLE   3,863,365 0 0
Nanometrics COM 630077105 713 28,179 SH   SOLE   28,179 0 0
Netflix COM 64110L106 162 1,085 SH   SOLE   1,085 0 0
Neurotrope COM 64129T207 756 80,705 SH   SOLE   80,705 0 0
NexGen Energy COM 65340P106 3,948 1,802,732 SH   SOLE   1,802,732 0 0
NICE Systems Ltd. COM 653656108 20 255 SH   SOLE   255 0 0
PepsiCo, Inc. COM 713448108 265 2,292 SH   SOLE   2,292 0 0
Philip Morris International COM 718172109 657 5,590 SH   SOLE   5,590 0 0
Procter And Gamble COM 742718109 10 110 SH   SOLE   110 0 0
ProMetic Life Sciences COM 74342Q104 1,127 873,549 SH   SOLE   873,549 0 0
QUALCOMM COM 747525103 889 16,099 SH   SOLE   16,099 0 0
Rudolph Technologies COM 781270103 1,622 70,977 SH   SOLE   70,977 0 0
Stifel Financial Corp. COM 860630102 626 13,625 SH   SOLE   13,625 0 0
Tesla Motors, Inc. COM 88160R101 1,656 4,580 SH   SOLE   4,580 0 0
Tower Semiconductor COM M87915274 4,250 178,186 SH   SOLE   178,186 0 0
The Walt Disney Company COM 254687106 30 285 SH   SOLE   285 0 0
Travelers Group COM 89417E109 1 6 SH   SOLE   6 0 0