The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| AGENUS INC | Common | 00847G705 | 7,953 | 2,439,554 | SH | SOLE | 2,439,554 | 0 | 0 | ||
| ALIMERA SCIENCES INC | Common | 016259103 | 8,301 | 6,241,581 | SH | SOLE | 6,241,581 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | Common | 03152W109 | 104,516 | 7,263,122 | SH | SOLE | 7,263,122 | 0 | 0 | ||
| AMICUS THERAPEUTICS INC | Common | 03152W109 | 1,763 | 1,500,000 | SH | Call | SOLE | 1,500,000 | 0 | 0 | |
| APELLIS PHARMACEUTICALS INC | Common | 03753U106 | 7,316 | 396,635 | SH | SOLE | 396,635 | 0 | 0 | ||
| ARGENX SE | Sponsored ADR | 04016X101 | 50,820 | 804,875 | SH | SOLE | 804,875 | 0 | 0 | ||
| ARRAY BIOPHARMA INC | Common | 04269X105 | 69,991 | 5,468,029 | SH | SOLE | 5,468,029 | 0 | 0 | ||
| ARRAY BIOPHARMA INC | Common | 04269X105 | 216 | 75,000 | SH | Call | SOLE | 75,000 | 0 | 0 | |
| ASCENDIS PHARMA | Sponsored ADR | 04351P101 | 67,342 | 1,681,024 | SH | SOLE | 1,681,024 | 0 | 0 | ||
| ASSEMBLY BIOSCIENCES INC | Common | 045396108 | 48,351 | 1,068,534 | SH | SOLE | 1,068,534 | 0 | 0 | ||
| ASTRAZENECA PLC | Sponsored ADR | 046353108 | 26,035 | 750,300 | SH | SOLE | 750,300 | 0 | 0 | ||
| AVEO PHARMACEUTICALS INC | Common | 053588109 | 11,179 | 4,006,893 | SH | SOLE | 4,006,893 | 0 | 0 | ||
| AVEXIS INC | Common | 05366U100 | 65,983 | 596,217 | SH | SOLE | 596,217 | 0 | 0 | ||
| BIOCRYST PHARMACEUTICALS INC | Common | 09058V103 | 1,673 | 340,821 | SH | SOLE | 340,821 | 0 | 0 | ||
| BIODELIVERY SCIENCE INTL | Common | 09060J106 | 7,285 | 2,469,488 | SH | SOLE | 2,469,488 | 0 | 0 | ||
| BIOMARIN PHARMACEUTICAL INC | Common | 09061G101 | 106,070 | 1,189,524 | SH | SOLE | 1,189,524 | 0 | 0 | ||
| BIOMARIN PHARMACEUTICAL INC | Common | 09061G101 | 135 | 300,000 | SH | Call | SOLE | 300,000 | 0 | 0 | |
| BRISTOL MYERS SQUIBB CO | Common | 110122108 | 27,957 | 456,223 | SH | SOLE | 456,223 | 0 | 0 | ||
| CASCADIAN THERAPEUTICS INC | Common | 14740B606 | 9,196 | 2,485,272 | SH | SOLE | 2,485,272 | 0 | 0 | ||
| CATALYST BIOSCIENCES INC | Common | 14888D208 | 5,456 | 400,000 | SH | SOLE | 400,000 | 0 | 0 | ||
| CATALYST PHARMACEUTICALS INC | Common | 14888U101 | 15,219 | 3,892,343 | SH | SOLE | 3,892,343 | 0 | 0 | ||
| CELLECTIS S A | Sponsored ADS | 15117K103 | 2,282 | 78,289 | SH | SOLE | 78,289 | 0 | 0 | ||
| CLOVIS ONCOLOGY INC | Common | 189464100 | 74,996 | 1,102,884 | SH | SOLE | 1,102,884 | 0 | 0 | ||
| CLOVIS ONCOLOGY INC | Common | 189464100 | 41 | 150,000 | SH | Call | SOLE | 150,000 | 0 | 0 | |
| CLOVIS ONCOLOGY INC | Common | 189464100 | 223 | 525,000 | SH | Call | SOLE | 525,000 | 0 | 0 | |
| DERMIRA INC | Common | 24983L104 | 42,271 | 1,520,000 | SH | SOLE | 1,520,000 | 0 | 0 | ||
| FENNEC PHARMACEUTICALS INC | Common | 31447P100 | 2,726 | 206,000 | SH | SOLE | 206,000 | 0 | 0 | ||
| GLOBAL BLOOD THERAPEUTICS INC | Common | 37890U108 | 72,479 | 1,841,896 | SH | SOLE | 1,841,896 | 0 | 0 | ||
| HORIZON PHARMA PLC | Common | G4617B105 | 64,768 | 4,436,183 | SH | SOLE | 4,436,183 | 0 | 0 | ||
| IMMUNOMEDICS INC | Common | 452907108 | 8,225 | 875,000 | SH | Call | SOLE | 875,000 | 0 | 0 | |
| IMMUNOMEDICS INC | Common | 452907108 | 259,602 | 16,064,461 | SH | SOLE | 16,064,461 | 0 | 0 | ||
| INCYTE CORP | Common | 45337C102 | 4,736 | 50,000 | SH | SOLE | 50,000 | 0 | 0 | ||
| INTEC PHARMA LTD | Common | M53644106 | 11,308 | 2,195,705 | SH | SOLE | 2,195,705 | 0 | 0 | ||
| IOVANCE BIOTHERAPEUTICS INC | Common | 462260100 | 42,028 | 5,253,450 | SH | SOLE | 5,253,450 | 0 | 0 | ||
| MEDICINES CO | Common | 584688105 | 35,448 | 1,296,560 | SH | SOLE | 1,296,560 | 0 | 0 | ||
| MACROGENICS INC | Common | 556099109 | 31 | 11,400 | SH | Call | SOLE | 11,400 | 0 | 0 | |
| MACROGENICS INC | Common | 556099109 | 6 | 3,100 | SH | Call | SOLE | 3,100 | 0 | 0 | |
| MIRATI THERAPEUTICS INC | Common | 60468T105 | 80,265 | 4,398,101 | SH | SOLE | 4,398,101 | 0 | 0 | ||
| MYOKARDIA INC | Common | 62857M105 | 16,765 | 398,207 | SH | SOLE | 398,207 | 0 | 0 | ||
| NEWLINK GENETICS CORP | Common | 651511107 | 6,451 | 795,412 | SH | SOLE | 795,412 | 0 | 0 | ||
| ONCOBIOLOGICS INC | Common | 68235M105 | 889 | 683,531 | SH | SOLE | 683,531 | 0 | 0 | ||
| ONCOBIOLOGICS INC - WARRANT A | Warrant | 68235M113 | 7 | 233,333 | SH | SOLE | 233,333 | 0 | 0 | ||
| ONCOBIOLOGICS INC - WARRANT B | Warrant | 68235M121 | 5 | 233,333 | SH | SOLE | 233,333 | 0 | 0 | ||
| PACIRA PHARMACEUTICALS INC | Common | 695127100 | 38,737 | 848,572 | SH | SOLE | 848,572 | 0 | 0 | ||
| PERNIX THERAPEUTICS HOLDINGS INC | Convertible Debt | 71426VAK4 | 2,530 | 6,000,000 | PRN | SOLE | 6,000,000 | 0 | 0 | ||
| TELIGENT INC | Common | 87960W104 | 18,329 | 5,049,431 | SH | SOLE | 5,049,431 | 0 | 0 | ||
| TG THERAPEUTICS INC | Common | 88322Q108 | 27,015 | 3,294,463 | SH | SOLE | 3,294,463 | 0 | 0 | ||
| VANDA PHARMACEUTICALS INC | Common | 921659108 | 21,416 | 1,408,946 | SH | SOLE | 1,408,946 | 0 | 0 | ||
| VERACYTE INC | Common | 92337F107 | 4,914 | 752,455 | SH | SOLE | 752,455 | 0 | 0 | ||
| VIEWRAY INC | Common | 92672L107 | 5,824 | 730,161 | SH | SOLE | 730,161 | 0 | 0 | ||
| VIVEVE MEDICAL INC | Common | 92852W204 | 5,135 | 1,033,276 | SH | SOLE | 1,033,276 | 0 | 0 | ||
| ZOGENIX INC | Common | 98978L204 | 50,596 | 1,263,313 | SH | SOLE | 1,263,313 | 0 | 0 | ||