The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AAC HLDGS INC COM 000307108 405 45,000 SH   DFND 1 0 0 45,000
ABBOTT LABS COM 002824100 30,247 530,000 SH   DFND 1 0 0 530,000
ABBVIE INC COM 00287Y109 1,886 19,500 SH   DFND 1 0 0 19,500
ABIOMED INC COM 003654100 5,060 27,000 SH   DFND 1 0 0 27,000
ACADIA HEALTHCARE COMPANY IN COM 00404A109 326 10,000 SH   DFND 1 0 0 10,000
ACADIA PHARMACEUTICALS INC COM 004225108 1,055 35,050 SH   DFND 1 0 0 35,050
AETNA INC NEW COM 00817Y108 3,969 22,000 SH   DFND 1 0 0 22,000
AGIOS PHARMACEUTICALS INC COM 00847X104 2,338 40,900 SH   DFND 1 0 0 40,900
ALDER BIOPHARMACEUTICALS INC COM 014339105 350 30,600 SH   DFND 1 0 0 30,600
ALEXION PHARMACEUTICALS INC COM 015351109 15,639 130,770 SH   DFND 1 0 0 130,770
ALIGN TECHNOLOGY INC COM 016255101 38,578 173,596 SH   DFND 1 0 0 173,596
ALKERMES PLC SHS G01767105 2,830 51,700 SH   DFND 1 0 0 51,700
ALLERGAN PLC SHS G0177J108 2,699 16,500 SH   DFND 1 0 0 16,500
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 2,808 22,100 SH   DFND 1 0 0 22,100
AMERISOURCEBERGEN CORP COM 03073E105 19,369 210,941 SH   DFND 1 0 0 210,941
AMGEN INC COM 031162100 14,216 81,750 SH   DFND 1 0 0 81,750
ANGIODYNAMICS INC COM 03475V101 1,691 101,700 SH   DFND 1 0 0 101,700
ANTHEM INC COM 036752103 40,788 181,243 SH   DFND 1 0 0 181,243
AURIS MED HLDG AG COM H03579101 1,281 2,169,625 SH   DFND 1 0 0 2,169,625
BAXTER INTL INC COM 071813109 13,962 216,000 SH   DFND 1 0 0 216,000
BECTON DICKINSON & CO COM 075887109 11,773 55,000 SH   DFND 1 0 0 55,000
BEIGENE LTD SPONSORED ADR 07725L102 10,129 103,650 SH   DFND 1 0 0 103,650
BIOGEN INC COM 09062X103 16,661 52,300 SH   DFND 1 0 0 52,300
BIOMARIN PHARMACEUTICAL INC COM 09061G101 4,017 45,050 SH   DFND 1 0 0 45,050
BIOVERATIV INC COM 09075E100 550 10,200 SH   DFND 1 0 0 10,200
BLUEBIRD BIO INC COM 09609G100 3,402 19,100 SH   DFND 1 0 0 19,100
BOSTON SCIENTIFIC CORP COM 101137107 17,254 696,000 SH   DFND 1 0 0 696,000
CARDINAL HEALTH INC COM 14149Y108 1,225 20,000 SH   DFND 1 0 0 20,000
CELGENE CORP COM 151020104 42,191 404,265 SH   DFND 1 0 0 404,265
CELLECTIS S A SPONSORED ADS 15117K103 710 24,350 SH   DFND 1 0 0 24,350
CENTENE CORP DEL COM 15135B101 11,641 115,390 SH   DFND 1 0 0 115,390
CERNER CORP COM 156782104 2,965 44,000 SH   DFND 1 0 0 44,000
CIGNA CORPORATION COM 125509109 11,708 57,650 SH   DFND 1 0 0 57,650
CLOVIS ONCOLOGY INC COM 189464100 1,224 18,000 SH   DFND 1 0 0 18,000
COHERUS BIOSCIENCES INC COM 19249H103 1,320 150,000 SH   DFND 1 0 0 150,000
COOPER COS INC COM NEW 216648402 4,855 22,300 SH   DFND 1 0 0 22,300
COTIVITI HLDGS INC COM 22164K101 699 21,708 SH   DFND 1 0 0 21,708
CVS HEALTH CORP COM 126650100 638 8,800 SH   DFND 1 0 0 8,800
DANAHER CORP DEL COM 235851102 18,750 202,000 SH   DFND 1 0 0 202,000
DENTSPLY SIRONA INC COM 24906P109 3,588 54,500 SH   DFND 1 0 0 54,500
DEXCOM INC COM 252131107 15,306 266,740 SH   DFND 1 0 0 266,740
DIREXION SHS ETF TR SP BIOTCH BL NEW 25490K323 2,989 38,400 SH   DFND 1 0 0 38,400
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 1,029 55,000 SH   DFND 1 0 0 55,000
EAGLE PHARMACEUTICALS INC COM 269796108 1,763 33,000 SH   DFND 1 0 0 33,000
EDWARDS LIFESCIENCES CORP COM 28176E108 21,212 188,200 SH   DFND 1 0 0 188,200
ENDO INTL PLC SHS G30401106 490 63,200 SH   DFND 1 0 0 63,200
ENVISION HEALTHCARE CORP COM 29414D100 450 13,026 SH   DFND 1 0 0 13,026
ESPERION THERAPEUTICS INC NEW COM 29664W105 514 7,800 SH   DFND 1 0 0 7,800
EXELIXIS INC COM 30161Q104 1,538 50,600 SH   DFND 1 0 0 50,600
EXPRESS SCRIPTS HLDG CO COM 30219G108 3,695 49,500 SH   DFND 1 0 0 49,500
GENMARK DIAGNOSTICS INC COM 372309104 3,226 773,677 SH   DFND 1 0 0 773,677
GILEAD SCIENCES INC COM 375558103 12,974 181,100 SH   DFND 1 0 0 181,100
GLAUKOS CORP COM 377322102 770 30,000 SH   DFND 1 0 0 30,000
GLOBUS MED INC CL A 379577208 2,008 48,850 SH   DFND 1 0 0 48,850
GW PHARMACEUTICALS PLC ADS 36197T103 653 4,950 SH   DFND 1 0 0 4,950
HALOZYME THERAPEUTICS INC COM 40637H109 1,560 77,000 SH   DFND 1 0 0 77,000
HCA HEALTHCARE INC COM 40412C101 1,871 21,300 SH   DFND 1 0 0 21,300
HEALTHCARE SVCS GRP INC COM 421906108 2,003 38,000 SH   DFND 1 0 0 38,000
SCHEIN HENRY INC COM 806407102 3,005 43,000 SH   DFND 1 0 0 43,000
HILL ROM HLDGS INC COM 431475102 14,324 169,939 SH   DFND 1 0 0 169,939
HMS HLDGS CORP COM 40425J101 907 53,500 SH   DFND 1 0 0 53,500
HOLOGIC INC COM 436440101 20,686 483,894 SH   DFND 1 0 0 483,894
HORIZON PHARMA PLC SHS G4617B105 11,593 794,062 SH   DFND 1 0 0 794,062
HUMANA INC COM 444859102 8,273 33,350 SH   DFND 1 0 0 33,350
HUTCHISON CHINA MEDTECH LTD SPONSORED ADR 44842L103 5,258 133,850 SH   DFND 1 0 0 133,850
ILLUMINA INC COM 452327109 32,748 149,873 SH   DFND 1 0 0 149,873
IMPAX LABORATORIES INC COM 45256B101 1,249 75,000 SH   DFND 1 0 0 75,000
INCYTE CORP COM 45337C102 21,933 231,576 SH   DFND 1 0 0 231,576
INOVIO PHARMACEUTICALS INC COM NEW 45773H201 579 140,100 SH   DFND 1 0 0 140,100
INSULET CORP COM 45784P101 1,242 18,000 SH   DFND 1 0 0 18,000
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208 8,720 182,200 SH   DFND 1 0 0 182,200
INTERCEPT PHARMACEUTICALS IN COM 45845P108 1,133 19,400 SH   DFND 1 0 0 19,400
INTERSECT ENT INC COM 46071F103 1,245 38,430 SH   DFND 1 0 0 38,430
INTRA CELLULAR THERAPIES INC COM 46116X101 1,339 92,500 SH   DFND 1 0 0 92,500
INTUITIVE SURGICAL INC COM NEW 46120E602 35,083 96,131 SH   DFND 1 0 0 96,131
IONIS PHARMACEUTICALS INC COM 462222100 12,908 256,706 SH   DFND 1 0 0 256,706
IRHYTHM TECHNOLOGIES INC COM 450056106 1,872 33,400 SH   DFND 1 0 0 33,400
ISHARES TR NASDAQ BIOTECH 464287556 1,441 13,500 SH   DFND 1 0 0 13,500
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 20,943 155,582 SH   DFND 1 0 0 155,582
JOHNSON & JOHNSON COM 478160104 3,633 26,000 SH   DFND 1 0 0 26,000
JUNO THERAPEUTICS INC COM 48205A109 1,915 41,900 SH   DFND 1 0 0 41,900
LABORATORY CORP AMER HLDGS COM NEW 50540R409 9,063 56,820 SH   DFND 1 0 0 56,820
LIGAND PHARMCEUTICALS INC COM NEW 53220K504 3,478 25,400 SH   DFND 1 0 0 25,400
LILLY ELI & CO COM 532457108 20,388 241,262 SH   DFND 1 0 0 241,262
LIVANOVA PLC SHS G5509L101 11,770 147,269 SH   DFND 1 0 0 147,269
MACROGENICS INC COM 556099109 10,724 564,401 SH   DFND 1 0 0 564,401
MASIMO CORP COM 574795100 1,442 17,000 SH   DFND 1 0 0 17,000
MCKESSON CORP COM 58155Q103 2,152 13,800 SH   DFND 1 0 0 13,800
MEDICINES CO COM 584688105 488 17,850 SH   DFND 1 0 0 17,850
MEDTRONIC PLC SHS G5960L103 17,523 217,000 SH   DFND 1 0 0 217,000
MERCK & CO INC COM 58933Y105 1,547 27,500 SH   DFND 1 0 0 27,500
MELINTA THERAPEUTICS INC COM 58549G100 507 32,100 SH   DFND 1 0 0 32,100
MOLINA HEALTHCARE INC COM 60855R100 3,336 43,500 SH   DFND 1 0 0 43,500
MYLAN N V SHS EURO N59465109 9,998 236,300 SH   DFND 1 0 0 236,300
MYRIAD GENETICS INC COM 62855J104 412 12,000 SH   DFND 1 0 0 12,000
NEKTAR THERAPEUTICS COM 640268108 4,461 74,700 SH   DFND 1 0 0 74,700
NEUROCRINE BIOSCIENCES INC COM 64125C109 4,229 54,500 SH   DFND 1 0 0 54,500
NEVRO CORP COM 64157F103 739 10,700 SH   DFND 1 0 0 10,700
NUVASIVE INC COM 670704105 1,890 32,312 SH   DFND 1 0 0 32,312
OBALON THERAPEUTICS INC COM 67424L100 317 48,000 SH   DFND 1 0 0 48,000
OMNICELL INC COM 68213N109 970 20,000 SH   DFND 1 0 0 20,000
PENUMBRA INC COM 70975L107 1,581 16,800 SH   DFND 1 0 0 16,800
PERRIGO CO PLC SHS G97822103 2,878 33,000 SH   DFND 1 0 0 33,000
PFIZER INC COM 717081103 1,058 29,200 SH   DFND 1 0 0 29,200
PORTOLA PHARMACEUTICALS INC COM 737010108 2,110 43,350 SH   DFND 1 0 0 43,350
PROTHENA CORP PLC SHS G72800108 1,175 31,350 SH   DFND 1 0 0 31,350
QUANTERIX CORP COM 74766Q101 1,799 83,800 SH   DFND 1 0 0 83,800
QIAGEN NV SHS NEW N72482123 1,751 56,611 SH   DFND 1 0 0 56,611
QUOTIENT LTD SHS G73268107 545 110,000 SH   DFND 1 0 0 110,000
RADIUS HEALTH INC COM NEW 750469207 1,074 33,800 SH   DFND 1 0 0 33,800
REGENERON PHARMACEUTICALS COM 75886F107 10,452 27,800 SH   DFND 1 0 0 27,800
RESMED INC COM 761152107 3,980 47,000 SH   DFND 1 0 0 47,000
SAGE THERAPEUTICS INC COM 78667J108 2,084 12,650 SH   DFND 1 0 0 12,650
SEATTLE GENETICS INC COM 812578102 2,862 53,500 SH   DFND 1 0 0 53,500
SHIRE PLC SPONSORED ADR 82481R106 8,754 56,435 SH   DFND 1 0 0 56,435
STRYKER CORP COM 863667101 14,137 91,300 SH   DFND 1 0 0 91,300
SUPERNUS PHARMACEUTICALS INC COM 868459108 9,580 240,400 SH   DFND 1 0 0 240,400
SURGERY PARTNERS INC COM 86881A100 375 31,000 SH   DFND 1 0 0 31,000
TABULA RASA HEALTHCARE INC COM 873379101 1,627 58,000 SH   DFND 1 0 0 58,000
TELADOC INC COM 87918A105 1,638 47,000 SH   DFND 1 0 0 47,000
TELEFLEX INC COM 879369106 3,483 14,000 SH   DFND 1 0 0 14,000
TENET HEALTHCARE CORP COM NEW 88033G407 9,344 616,796 SH   DFND 1 0 0 616,796
TESARO INC COM 881569107 5,975 72,100 SH   DFND 1 0 0 72,100
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADR 881624209 12,733 671,940 SH   DFND 1 0 0 671,940
THERAVANCE BIOPHARMA INC COM G8807B106 296 10,628 SH   DFND 1 0 0 10,628
THERMO FISHER SCIENTIFIC INC COM 883556102 4,900 25,808 SH   DFND 1 0 0 25,808
ULTRAGENYX PHARMACEUTICAL INC COM 90400D108 1,897 40,900 SH   DFND 1 0 0 40,900
UNITED THERAPEUTICS CORP DEL COM 91307C102 2,545 17,200 SH   DFND 1 0 0 17,200
UNITEDHEALTH GROUP INC COM 91324P102 31,506 142,910 SH   DFND 1 0 0 142,910
VARIAN MED SYS INC COM 92220P105 778 7,000 SH   DFND 1 0 0 7,000
VERTEX PHARMACEUTICALS INC COM 92532F100 14,418 96,210 SH   DFND 1 0 0 96,210
WALGREENS BOOTS ALLIANCE INC COM 931427108 21,536 296,560 SH   DFND 1 0 0 296,560
WRIGHT MED GROUP NV ORD SHS 0.03 PAR N96617118 12,028 541,801 SH   DFND 1 0 0 541,801
ZIMMER BIOMET HLDGS INC COM 98956P102 10,016 83,000 SH   DFND 1 0 0 83,000