The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Achillion Pharmaceuticals Inc | COM | 00448Q201 | 39,015 | 13,546,902 | SH | SOLE | 1 | 13,546,902 | 0 | 0 | |
| Agenus Inc | COM NEW | 00847G705 | 14,115 | 4,329,816 | SH | SOLE | 1 | 4,329,816 | 0 | 0 | |
| Alnylam Pharmaceuticals Inc | COM | 02043Q107 | 45,582 | 358,774 | SH | SOLE | 1 | 358,774 | 0 | 0 | |
| Arbutus Biopharma Corp | COM | 03879J100 | 26,016 | 5,151,615 | SH | SOLE | 1 | 5,151,615 | 0 | 0 | |
| argenx NV | SPONSORED ADR | 04016X101 | 1,595 | 25,260 | SH | SOLE | 1 | 25,260 | 0 | 0 | |
| Atara Biotherapeutics Inc | COM | 046513107 | 10,066 | 556,118 | SH | SOLE | 1 | 556,118 | 0 | 0 | |
| Avexis Inc | COM | 05366U100 | 31,125 | 281,242 | SH | SOLE | 1 | 281,242 | 0 | 0 | |
| BioCryst Pharmaceuticals Inc | COM | 09058V103 | 16,560 | 3,372,674 | SH | SOLE | 1 | 3,372,674 | 0 | 0 | |
| Bovie Medical Corp | COM | 10211F100 | 4,557 | 1,752,611 | SH | SOLE | 1 | 1,752,611 | 0 | 0 | |
| Bristol-Myers Squibb Co | COM | 110122108 | 51,442 | 839,452 | SH | SOLE | 1 | 839,452 | 0 | 0 | |
| Corium International Inc | COM | 21887L107 | 16,334 | 1,699,653 | SH | SOLE | 1 | 1,699,653 | 0 | 0 | |
| Dicerna Pharmaceuticals Inc | COM | 253031108 | 44,142 | 5,035,662 | SH | SOLE | 1 | 5,035,662 | 0 | 0 | |
| Edwards Lifesciences Corp | COM | 28176E108 | 13,863 | 123,000 | SH | SOLE | 1 | 123,000 | 0 | 0 | |
| Five Prime Therapeutics Inc | COM | 33830X104 | 2,200 | 100,377 | SH | SOLE | 1 | 100,377 | 0 | 0 | |
| Global Blood Therapeutics Inc | COM | 37890U108 | 23,676 | 601,683 | SH | SOLE | 1 | 601,683 | 0 | 0 | |
| La Jolla Pharmaceutical Co | COM PAR $.0001 2 | 503459604 | 34,213 | 1,063,170 | SH | SOLE | 1 | 1,063,170 | 0 | 0 | |
| Masimo Corp | COM | 574795100 | 10,252 | 120,900 | SH | SOLE | 1 | 120,900 | 0 | 0 | |
| Myokardia Inc | COM | 62857M105 | 10,848 | 257,663 | SH | SOLE | 1 | 257,663 | 0 | 0 | |
| Odonate Therapeutics Inc | COM | 676079106 | 6,768 | 297,555 | SH | SOLE | 1 | 297,555 | 0 | 0 | |
| OraSure Technologies Inc | COM | 68554V108 | 16,568 | 878,452 | SH | SOLE | 1 | 878,452 | 0 | 0 | |
| Oxford Immunotec Global PLC | ORD SHS | G6855A103 | 5,250 | 375,792 | SH | SOLE | 1 | 375,792 | 0 | 0 | |
| Proteostasis Therapeutics Inc | COM | 74373B109 | 8,745 | 1,500,000 | SH | SOLE | 1 | 1,500,000 | 0 | 0 | |
| PTC Therapeutics Inc | COM | 69366J200 | 68,890 | 4,130,115 | SH | SOLE | 1 | 4,130,115 | 0 | 0 | |
| Regenxbio Inc | COM | 75901B107 | 51,910 | 1,561,210 | SH | SOLE | 1 | 1,561,210 | 0 | 0 | |
| Revance Therapeutics Inc | COM | 761330109 | 824 | 23,038 | SH | SOLE | 1 | 23,038 | 0 | 0 | |
| SENSUS HEATLHCARE INC | *W EXP 06/08/201 | 81728J117 | 98 | 151,400 | SH | SOLE | 1 | 151,400 | 0 | 0 | |
| Tactile Systems Technology Inc | COM | 87357P100 | 6,096 | 210,366 | SH | SOLE | 1 | 210,366 | 0 | 0 | |
| Uniqure NV | SHS | N90064101 | 7,905 | 403,524 | SH | SOLE | 1 | 403,524 | 0 | 0 | |
| Vericel Corp | COM | 92346J108 | 7,111 | 1,304,801 | SH | SOLE | 1 | 1,304,801 | 0 | 0 | |
| Viewray Inc | COM | 92672L107 | 12,484 | 1,348,210 | SH | SOLE | 1 | 1,348,210 | 0 | 0 | |
| Viveve Medical Inc | COM NEW | 92852W204 | 8,315 | 1,672,998 | SH | SOLE | 1 | 1,672,998 | 0 | 0 | |
| Zynerba Pharmaceuticals Inc | COM | 98986X109 | 2,540 | 202,859 | SH | SOLE | 1 | 202,859 | 0 | 0 | |