The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Achillion Pharmaceuticals In COM 00448Q201 38,324 13,541,997 SH   SOLE 1 13,541,997 0 0
Adverum Biotechnologies Inc COM 00773U108 935 176,372 SH   SOLE 1 176,372 0 0
Agenus Inc COM NEW 00847G705 21,282 9,375,451 SH   SOLE 1 9,375,451 0 0
Alnylam Pharmaceuticals Inc COM 02043Q107 34,688 352,200 SH   SOLE 1 352,200 0 0
Arbutus Biopharma Corp COM 03879J100 37,708 5,165,499 SH   SOLE 1 5,165,499 0 0
Argenx Se SPONSORED ADR 04016X101 2,118 25,559 SH   SOLE 1 25,559 0 0
Arrowhead Pharmaceuticals In COM 04280A100 112,874 8,299,542 SH   SOLE 1 8,299,542 0 0
Bellicum Pharmaceuticals Inc COM 079481107 1,109 150,289 SH   SOLE 1 150,289 0 0
Bovie Medical Corp COM 10211F100 9,057 2,082,137 SH   SOLE 1 2,082,137 0 0
Bristol Myers Squibb Co COM 110122108 50,009 903,672 SH   SOLE 1 903,672 0 0
Caredx Inc COM 14167L103 9,358 764,532 SH   SOLE 1 764,532 0 0
Corium Intl Inc COM 21887L107 15,405 1,923,217 SH   SOLE 1 1,923,217 0 0
Dicerna Pharmaceuticals Inc COM 253031108 61,799 5,044,813 SH   SOLE 1 5,044,813 0 0
Electrocore Inc COM 28531P103 8,338 505,000 SH   SOLE 1 505,000 0 0
Homology Medicines Inc COM 438083107 4,619 226,431 SH   SOLE 1 226,431 0 0
Illumina Inc COM 452327109 13,869 49,658 SH   SOLE 1 49,658 0 0
La Jolla Pharmaceutical Co COM PAR $.0001 2 503459604 39,259 1,345,881 SH   SOLE 1 1,345,881 0 0
Livanova PLC SHS G5509L101 43,022 431,000 SH   SOLE 1 431,000 0 0
Masimo Corp COM 574795100 24,368 249,543 SH   SOLE 1 249,543 0 0
Motus Gi Hldgs Inc COM 62014P108 428 59,478 SH   SOLE 1 59,478 0 0
Myokardia Inc COM 62857M105 12,978 261,395 SH   SOLE 1 261,395 0 0
Neuronetics Inc COM 64131A105 5,056 190,000 SH   SOLE 1 190,000 0 0
Novavax Inc COM 670002104 3,543 2,644,346 SH   SOLE 1 2,644,346 0 0
Novus Therapeutics Inc COM 67011N105 2,113 301,799 SH   SOLE 1 301,799 0 0
Nuvectra Corp COM 67075N108 7,864 383,030 SH   SOLE 1 383,030 0 0
Odonate Therapeutics Inc COM 676079106 6,102 276,368 SH   SOLE 1 276,368 0 0
Polarityte Inc COM 731094108 10,044 426,670 SH   SOLE 1 426,670 0 0
Proteostasis Therapeutics In COM 74373B109 3,006 1,077,408 SH   SOLE 1 1,077,408 0 0
Ptc Therapeutics Inc COM 69366J200 137,406 4,073,690 SH   SOLE 1 4,073,690 0 0
Qiagen NV SHS NEW N72482123 19,143 529,385 SH   SOLE 1 529,385 0 0
Regenxbio Inc COM 75901B107 149,208 2,079,555 SH   SOLE 1 2,079,555 0 0
Rocket Pharmaceuticals Inc COM 77313F106 289,448 14,969,744 SH   SOLE 1 14,969,744 0 0
Sarepta Therapeutics Inc COM 803607100 129,345 978,551 SH   SOLE 1 978,551 0 0
Solid Biosciences Inc COM 83422E105 22,753 675,771 SH   SOLE 1 675,771 0 0
Tapimmune Inc COM PAR 876033408 1,886 200,000 SH   SOLE 1 200,000 0 0
Uniqure NV SHS N90064101 15,474 409,370 SH   SOLE 1 409,370 0 0
Vericel Corp COM 92346J108 21,514 2,217,916 SH   SOLE 1 2,217,916 0 0
Viewray Inc COM 92672L107 10,201 1,474,156 SH   SOLE 1 1,474,156 0 0
Viveve Med Inc COM NEW 92852W204 7,782 2,861,023 SH   SOLE 1 2,861,023 0 0
Vivus Inc 4.5 05/01/2020 NOTE 4.500% 5/0 928551AA8 3,140 4,000,000 SH   SOLE 1 4,000,000 0 0