The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACHILLION PHARMACEUTICALS IN | COM | 00448Q201 | 11,320 | 4,000,000 | SH | DFND | 1 | 4,000,000 | 0 | 0 | |
| ACHIEVE LIFE SCIENCE INC | COM NEW | 004468203 | 234 | 62,000 | SH | DFND | 1 | 62,000 | 0 | 0 | |
| ALIMERA SCIENCES INC | COM | 016259103 | 6,785 | 6,936,000 | SH | DFND | 1 | 6,936,000 | 0 | 0 | |
| ALEXION PHARMACEUTICALS INC | COM | 015351109 | 13,905 | 112,000 | SH | DFND | 1 | 112,000 | 0 | 0 | |
| AMAG PHARMACEUTICALS INC | COM | 00163U106 | 40,560 | 2,080,000 | SH | DFND | 1 | 2,080,000 | 0 | 0 | |
| AMAZON COM INC | COM | 023135106 | 3,400 | 2,000 | SH | DFND | 1 | 2,000 | 0 | 0 | |
| BLUE APRON HLDGS INC | CL A | 09523Q101 | 13,400 | 4,000,000 | SH | DFND | 1 | 4,000,000 | 0 | 0 | |
| ALPHATEC HOLDINGS INC | COM NEW | 02081G201 | 9,627 | 3,230,414 | SH | DFND | 1 | 3,230,414 | 0 | 0 | |
| ANTARES PHARMA INC | COM | 036642106 | 31,089 | 12,050,000 | SH | DFND | 1 | 12,050,000 | 0 | 0 | |
| BEST BUY INC | COM | 086516101 | 10,441 | 140,000 | SH | DFND | 1 | 140,000 | 0 | 0 | |
| BIODELIVERY SCIENCES INTL IN | COM | 09060J106 | 357 | 120,889 | SH | DFND | 1 | 120,889 | 0 | 0 | |
| B & G FOODS INC NEW | COM | 05508R106 | 20,930 | 700,000 | SH | DFND | 1 | 700,000 | 0 | 0 | |
| BLUEBIRD BIO INC | COM | 09609G100 | 28,251 | 180,000 | SH | DFND | 1 | 180,000 | 0 | 0 | |
| CHEESECAKE FACTORY INC | COM | 163072101 | 28,631 | 520,000 | SH | Call | DFND | 1 | 520,000 | 0 | 0 |
| CATABASIS PHARMACEUTICALS IN | COM | 14875P107 | 1,918 | 2,000,000 | SH | DFND | 1 | 2,000,000 | 0 | 0 | |
| CELGENE CORP | COM | 151020104 | 13,899 | 175,000 | SH | DFND | 1 | 175,000 | 0 | 0 | |
| CERECOR INC | COM | 15671L109 | 71,238 | 16,414,400 | SH | DFND | 1 | 16,414,400 | 0 | 0 | |
| CLOVIS ONCOLOGY INC | COM | 189464100 | 28,373 | 624,000 | SH | DFND | 1 | 624,000 | 0 | 0 | |
| CHIMERIX INC | COM | 16934W106 | 5,988 | 1,258,000 | SH | DFND | 1 | 1,258,000 | 0 | 0 | |
| CAMPBELL SOUP CO | COM | 134429109 | 41,351 | 1,020,000 | SH | Call | DFND | 1 | 1,020,000 | 0 | 0 |
| CATALYST PHARMACEUTICALS INC | COM | 14888U101 | 5,304 | 1,700,000 | SH | DFND | 1 | 1,700,000 | 0 | 0 | |
| CRISPR THERAPEUTICS AG | NAMEN AKT | H17182108 | 7,286 | 124,000 | SH | DFND | 1 | 124,000 | 0 | 0 | |
| CVS HEALTH CORP | COM | 126650100 | 32,175 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
| DEPOMED INC | COM | 249908104 | 7,857 | 1,177,900 | SH | DFND | 1 | 1,177,900 | 0 | 0 | |
| DESPEGAR COM CORP | ORD SHS | G27358103 | 33,384 | 1,592,000 | SH | DFND | 1 | 1,592,000 | 0 | 0 | |
| DEL FRISCOS RESTAURANT GROUP | COM | 245077102 | 12,600 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
| DSW INC | CL A | 23334L102 | 7,230 | 280,000 | SH | DFND | 1 | 280,000 | 0 | 0 | |
| DYNATRONICS CORP | COM NEW | 268157401 | 1,557 | 541,417 | SH | DFND | 1 | 541,417 | 0 | 0 | |
| ENANTA PHARMACEUTICALS INC | COM | 29251M106 | 14,372 | 124,000 | SH | DFND | 1 | 124,000 | 0 | 0 | |
| EDGEWELL PERS CARE CO | COM | 28035Q102 | 55,102 | 1,092,000 | SH | DFND | 1 | 1,092,000 | 0 | 0 | |
| EDGEWELL PERS CARE CO | COM | 28035Q102 | 17,661 | 350,000 | SH | Call | DFND | 1 | 350,000 | 0 | 0 |
| EYEGATE PHARMACEUTICALS INC | COM | 30233M107 | 8,905 | 16,802,500 | SH | DFND | 1 | 16,802,500 | 0 | 0 | |
| FACEBOOK INC | CL A | 30303M102 | 3,498 | 18,000 | SH | DFND | 1 | 18,000 | 0 | 0 | |
| FRESHPET INC | COM | 358039105 | 27,450 | 1,000,000 | SH | Call | DFND | 1 | 1,000,000 | 0 | 0 |
| GAP INC DEL | COM | 364760108 | 27,855 | 860,000 | SH | DFND | 1 | 860,000 | 0 | 0 | |
| HAIN CELESTIAL GROUP INC | COM | 405217100 | 23,840 | 800,000 | SH | Call | DFND | 1 | 800,000 | 0 | 0 |
| HANESBRANDS INC | COM | 410345102 | 28,186 | 1,280,000 | SH | DFND | 1 | 1,280,000 | 0 | 0 | |
| HARLEY DAVIDSON INC | COM | 412822108 | 42,080 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
| INCYTE CORP | COM | 45337C102 | 28,676 | 428,000 | SH | DFND | 1 | 428,000 | 0 | 0 | |
| INTELLIPHARMACEUTICS INTL IN | COM | 458173101 | 3,841 | 8,600,000 | SH | DFND | 1 | 8,600,000 | 0 | 0 | |
| MICHAEL KORS HLDGS LTD | SHS | G60754101 | 27,839 | 418,000 | SH | DFND | 1 | 418,000 | 0 | 0 | |
| MALLINCKRODT PUB LTD CO | SHS | G5785G107 | 44,784 | 2,400,000 | SH | DFND | 1 | 2,400,000 | 0 | 0 | |
| NAKED BRAND GROUP LIMITED | ORD SHS | Q6519T109 | 10,144 | 1,600,000 | SH | DFND | 1 | 1,600,000 | 0 | 0 | |
| NOVAN INC | COM | 66988N106 | 1,470 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
| NOVELION THERAPEUTICS INC | COM NEW | 67001K202 | 6,830 | 1,856,000 | SH | DFND | 1 | 1,856,000 | 0 | 0 | |
| SPARK THERAPEUTICS INC | COM | 84652J103 | 12,414 | 150,000 | SH | DFND | 1 | 150,000 | 0 | 0 | |
| ONCONOVA THERAPEUTICS INC | COM NEW | 68232V306 | 683 | 1,688,235 | SH | DFND | 1 | 1,688,235 | 0 | 0 | |
| PROGENICS PHARMACEUTICALS IN | COM | 743187106 | 20,389 | 2,536,000 | SH | DFND | 1 | 2,536,000 | 0 | 0 | |
| PLAYA HOTELS & RESORTS NV | SHS | N70544106 | 31,709 | 2,936,000 | SH | DFND | 1 | 2,936,000 | 0 | 0 | |
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 11,546 | 1,132,000 | SH | DFND | 1 | 1,132,000 | 0 | 0 | |
| PERNIX THERAPEUTICS HLDGS IN | DBCV 4.250% 4/0 | 71426VAK4 | 9,494 | 21,760,000 | PRN | DFND | 1 | 21,760,000 | 0 | 0 | |
| PAPA JOHNS INTL INC | COM | 698813102 | 12,680 | 250,000 | SH | DFND | 1 | 250,000 | 0 | 0 | |
| PAPA JOHNS INTL INC | COM | 698813102 | 38,040 | 750,000 | SH | Call | DFND | 1 | 750,000 | 0 | 0 |
| QURATE RETAIL INC | COM SER A | 74915M100 | 10,398 | 490,000 | SH | DFND | 1 | 490,000 | 0 | 0 | |
| REGENERON PHARMACEUTICALS | COM | 75886F107 | 44,159 | 128,000 | SH | DFND | 1 | 128,000 | 0 | 0 | |
| RITTER PHARMACEUTICALS INC | COM NEW | 767836307 | 36 | 14,000 | SH | DFND | 1 | 14,000 | 0 | 0 | |
| STRONGBRIDGE BIOPHARMA PLC | SHS USD | G85347105 | 12,948 | 2,158,000 | SH | DFND | 1 | 2,158,000 | 0 | 0 | |
| SEAWORLD ENTMT INC | COM | 81282V100 | 34,388 | 1,576,000 | SH | DFND | 1 | 1,576,000 | 0 | 0 | |
| SCIENTIFIC GAMES CORP | COM | 80874P109 | 18,087 | 368,000 | SH | DFND | 1 | 368,000 | 0 | 0 | |
| SMUCKER J M CO | COM NEW | 832696405 | 34,824 | 324,000 | SH | DFND | 1 | 324,000 | 0 | 0 | |
| SOLID BIOSCIENCES INC | COM | 83422E105 | 6,413 | 180,000 | SH | DFND | 1 | 180,000 | 0 | 0 | |
| SIMPLY GOOD FOODS CO | COM | 82900L102 | 21,082 | 1,460,000 | SH | DFND | 1 | 1,460,000 | 0 | 0 | |
| SPDR S&P 500 ETF TR | TR UNIT | 78462F103 | 195,322 | 720,000 | SH | Put | DFND | 1 | 720,000 | 0 | 0 |
| STEADYMED LTD | SHS | M84920103 | 2,237 | 497,044 | SH | DFND | 1 | 497,044 | 0 | 0 | |
| THERAVANCE BIOPHARMA INC | COM | G8807B106 | 26,762 | 1,180,000 | SH | DFND | 1 | 1,180,000 | 0 | 0 | |
| TEMPUR SEALY INTL INC | COM | 88023U101 | 41,131 | 856,000 | SH | DFND | 1 | 856,000 | 0 | 0 | |
| VICAL INC | COM NEW | 925602203 | 5,015 | 4,360,500 | SH | DFND | 1 | 4,360,500 | 0 | 0 | |
| VANDA PHARMACEUTICALS INC | COM | 921659108 | 42,367 | 2,224,000 | SH | DFND | 1 | 2,224,000 | 0 | 0 | |
| VAXART INC | COM NEW | 92243A200 | 235 | 77,599 | SH | DFND | 1 | 77,599 | 0 | 0 | |
| VOYAGER THERAPEUTICS INC | COM | 92915B106 | 8,441 | 432,000 | SH | DFND | 1 | 432,000 | 0 | 0 | |
| YELP INC | CL A | 985817105 | 7,836 | 200,000 | SH | DFND | 1 | 200,000 | 0 | 0 | |
| ZAFGEN INC | COM | 98885E103 | 15,345 | 1,500,000 | SH | DFND | 1 | 1,500,000 | 0 | 0 | |
| ZOES KITCHEN INC | COM | 98979J109 | 5,791 | 593,321 | SH | DFND | 1 | 593,321 | 0 | 0 | |