The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACHILLION PHARMACEUTICALS IN COM 00448Q201 7,360 2,000,000 SH   DFND 1 2,000,000 0 0
ALIMERA SCIENCES INC COM 016259103 6,797 6,936,000 SH   DFND 1 6,936,000 0 0
ALPHATEC HOLDINGS INC COM NEW 02081G201 11,122 3,300,414 SH   DFND 1 3,300,414 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 41,600 2,080,000 SH   DFND 1 2,080,000 0 0
ANTARES PHARMA INC COM 036642106 30,643 9,120,000 SH   DFND 1 9,120,000 0 0
APRICUS BIOSCIENCES INC COM NEW 03832V307 1,426 4,600,000 SH   DFND 1 4,600,000 0 0
ASSERTIO THERAPEUTICS INC COM 04545L107 17,640 3,000,000 SH   DFND 1 3,000,000 0 0
AT&T INC COM 00206R102 3,358 100,000 SH   DFND 1 100,000 0 0
AVIS BUDGET GROUP COM 053774105 32,140 1,000,000 SH   DFND 1 1,000,000 0 0
BEST BUY INC COM 086516101 15,872 200,000 SH   DFND 1 200,000 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 9,218 3,292,000 SH   DFND 1 3,292,000 0 0
BLUE APRON HLDGS INC CL A 09523Q101 5,160 3,000,000 SH Call DFND 1 3,000,000 0 0
BLUEBIRD BIO INC COM 09609G100 12,848 88,000 SH   DFND 1 88,000 0 0
BRINKER INTL INC COM 109641100 9,346 200,000 SH   DFND 1 200,000 0 0
CAMPBELL SOUP CO COM 134429109 73,260 2,000,000 SH Call DFND 1 2,000,000 0 0
CASTLE BRANDS INC COM 148435100 107 100,000 SH   DFND 1 100,000 0 0
CATALYST PHARMACEUTICALS INC COM 14888U101 6,320 1,672,000 SH   DFND 1 1,672,000 0 0
CELLECTIS S A SPONSORED ADS 15117K103 16,932 600,000 SH   DFND 1 600,000 0 0
CERECOR INC COM 15671L109 81,727 17,500,400 SH   DFND 1 17,500,400 0 0
CHEESECAKE FACTORY INC COM 163072101 58,894 1,100,000 SH Call DFND 1 1,100,000 0 0
CHIMERIX INC COM 16934W106 5,057 1,300,000 SH   DFND 1 1,300,000 0 0
CITIUS PHARMACEUTICALS INC COM NEW 17322U207 100 58,431 SH   DFND 1 58,431 0 0
CLOVIS ONCOLOGY INC COM 189464100 48,049 1,636,000 SH   DFND 1 1,636,000 0 0
CVS HEALTH CORP COM 126650100 7,872 100,000 SH   DFND 1 100,000 0 0
DEL FRISCOS RESTAURANT GROUP COM 245077102 31,175 3,756,000 SH   DFND 1 3,756,000 0 0
DESPEGAR COM CORP ORD SHS G27358103 26,385 1,564,000 SH   DFND 1 1,564,000 0 0
DYNATRONICS CORP COM NEW 268157401 1,570 551,046 SH   DFND 1 551,046 0 0
EDGEWELL PERS CARE CO COM 28035Q102 46,230 1,000,000 SH   DFND 1 1,000,000 0 0
ENANTA PHARMACEUTICALS INC COM 29251M106 38,970 456,000 SH   DFND 1 456,000 0 0
EYEGATE PHARMACEUTICALS INC COM 30233M107 5,209 16,802,500 SH   DFND 1 16,802,500 0 0
FACEBOOK INC CL A 30303M102 8,223 50,000 SH   DFND 1 50,000 0 0
FARFETCH LTD ORD SH CL A 30744W107 5,446 200,000 SH   DFND 1 200,000 0 0
FLOOR & DECOR HLDGS INC CL A 339750101 9,051 300,000 SH   DFND 1 300,000 0 0
GAP INC DEL COM 364760108 15,117 524,000 SH   DFND 1 524,000 0 0
HAIN CELESTIAL GROUP INC COM 405217100 54,240 2,000,000 SH Call DFND 1 2,000,000 0 0
HAIN CELESTIAL GROUP INC COM 405217100 27,120 1,000,000 SH   DFND 1 1,000,000 0 0
HANESBRANDS INC COM 410345102 36,860 2,000,000 SH   DFND 1 2,000,000 0 0
HARLEY DAVIDSON INC COM 412822108 37,327 824,000 SH   DFND 1 824,000 0 0
INCYTE CORP COM 45337C102 48,356 700,000 SH Call DFND 1 700,000 0 0
INTELLIPHARMACEUTICS INTL IN COM 458173309 2,305 860,000 SH   DFND 1 860,000 0 0
LULULEMON ATHLETICA INC COM 550021109 8,125 50,000 SH   DFND 1 50,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 17,130 80,000 SH   DFND 1 80,000 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 45,137 1,540,000 SH   DFND 1 1,540,000 0 0
MEDIFAST INC COM 58470H101 5,317 24,000 SH   DFND 1 24,000 0 0
MICHAEL KORS HLDGS LTD SHS G60754101 36,748 536,000 SH   DFND 1 536,000 0 0
NAKED BRAND GROUP LIMITED ORD SHS Q6519T109 4,917 1,828,000 SH   DFND 1 1,828,000 0 0
NOVELION THERAPEUTICS INC COM NEW 67001K202 5,494 1,856,000 SH   DFND 1 1,856,000 0 0
ONCONOVA THERAPEUTICS INC COM PAR 68232V405 816 111,216 SH   DFND 1 111,216 0 0
ORAMED PHARM INC COM NEW 68403P203 3,039 624,000 SH   DFND 1 624,000 0 0
PAIN THERAPEUTICS INC COM NEW 69562K506 2,186 2,164,000 SH   DFND 1 2,164,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 11,640 1,200,000 SH   DFND 1 1,200,000 0 0
PDL BIOPHARMA INC COM 69329Y104 4,734 1,800,000 SH   DFND 1 1,800,000 0 0
PENNEY J C INC COM 708160106 3,818 2,300,000 SH Call DFND 1 2,300,000 0 0
PERNIX THERAPEUTICS HLDGS IN DBCV 4.250% 4/0 71426VAK4 9,531 21,760,000 PRN   DFND 1 21,760,000 0 0
PETMED EXPRESS INC COM 716382106 17,561 532,000 SH   DFND 1 532,000 0 0
PLAYA HOTELS & RESORTS NV SHS N70544106 32,280 3,352,000 SH   DFND 1 3,352,000 0 0
PROGENICS PHARMACEUTICALS IN COM 743187106 38,611 6,158,000 SH   DFND 1 6,158,000 0 0
QURATE RETAIL INC COM SER A 74915M100 19,989 900,000 SH   DFND 1 900,000 0 0
RADIUS HEALTH INC COM NEW 750469207 11,712 658,000 SH   DFND 1 658,000 0 0
RALPH LAUREN CORP CL A 751212101 29,986 218,000 SH   DFND 1 218,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 30,303 75,000 SH   DFND 1 75,000 0 0
RITTER PHARMACEUTICALS INC COM NEW 767836307 339 182,000 SH   DFND 1 182,000 0 0
SCIENTIFIC GAMES CORP COM 80874P109 22,860 900,000 SH   DFND 1 900,000 0 0
SMUCKER J M CO COM NEW 832696405 52,947 516,000 SH   DFND 1 516,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 7,738 164,000 SH   DFND 1 164,000 0 0
SPARK THERAPEUTICS INC COM 84652J103 12,437 228,000 SH   DFND 1 228,000 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 197,690 680,000 SH Put DFND 1 680,000 0 0
STRONGBRIDGE BIOPHARMA PLC SHS USD G85347105 12,853 2,650,000 SH   DFND 1 2,650,000 0 0
TAILORED BRANDS INC COM 87403A107 7,557 300,000 SH   DFND 1 300,000 0 0
TEMPUR SEALY INTL INC COM 88023U101 5,290 100,000 SH   DFND 1 100,000 0 0
TITAN PHARMACEUTICALS INC DE COM NEW 888314309 46 220,000 SH   DFND 1 220,000 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 37,341 292,000 SH   DFND 1 292,000 0 0
VANDA PHARMACEUTICALS INC COM 921659108 20,655 900,000 SH   DFND 1 900,000 0 0
VAXART INC COM NEW 92243A200 428 150,000 SH   DFND 1 150,000 0 0
VICAL INC COM NEW 925602203 5,974 4,360,500 SH   DFND 1 4,360,500 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 32,618 1,724,000 SH   DFND 1 1,724,000 0 0
ZAFGEN INC COM 98885E103 13,607 1,164,000 SH   DFND 1 1,164,000 0 0