The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABB LTD SPONSORED ADR 000375204 2,918 123,500 SH   SOLE 0 123,500 0 0
ABBVIE INC COM 00287Y109 378 4,000 SH   SOLE 0 4,000 0 0
ACCELERON PHARMA INC COM 00434H108 7,377 128,900 SH   SOLE 0 128,900 0 0
ACORDA THERAPEUTICS INC NOTE 1.750% 6/1 00484MAA4 340 400,000 PRN   SOLE 0 400,000 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 5,784 75,000 SH   SOLE 0 75,000 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 47,440 1,739,000 SH   SOLE 0 1,739,000 0 0
ALEXANDRIA REAL ESTATE EQ IN COM 015271109 1,258 10,000 SH   SOLE 0 10,000 0 0
ALLAKOS INC COM 01671P100 1,575 35,000 SH   SOLE 0 35,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 5,426 62,000 SH   SOLE 0 62,000 0 0
ALTAIR ENGR INC COM CL A 021369103 43,450 1,000,000 SH   SOLE 0 1,000,000 0 0
AMERIGAS PARTNERS L P UNIT L P INT 030975106 1,304 33,000 SH   SOLE 0 33,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 8,463 700,000 SH   SOLE 0 700,000 0 0
ANAPTYSBIO INC COM 032724106 26,167 262,275 SH   SOLE 0 262,275 0 0
APTIV PLC SHS G6095L109 22,619 269,600 SH   SOLE 0 269,600 0 0
ARGENX SE SPONSORED ADR 04016X101 25,406 335,000 SH   SOLE 0 335,000 0 0
ARISTA NETWORKS INC COM 040413106 17,547 66,000 SH   SOLE 0 66,000 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 109,472 1,544,900 SH   SOLE 0 1,544,900 0 0
ASML HOLDING N V N Y REGISTRY SHS N07059210 32,339 172,000 SH   SOLE 0 172,000 0 0
ATLANTICA YIELD PLC SHS G0751N103 17,822 866,000 SH   SOLE 0 866,000 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 10,887 275,000 SH   SOLE 0 275,000 0 0
AVROBIO INC COM 05455M100 46,421 928,891 SH   SOLE 0 928,891 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103 7,989 1,047,000 SH   SOLE 0 1,047,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 11,040 294,000 SH   SOLE 0 294,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 12,800 132,000 SH   SOLE 0 132,000 0 0
BLUEBIRD BIO INC COM 09609G100 40,530 277,603 SH   SOLE 0 277,603 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 22,013 282,000 SH   SOLE 0 282,000 0 0
BRANDYWINE RLTY TR SH BEN INT NEW 105368203 1,800 114,500 SH   SOLE 0 114,500 0 0
BROOKFIELD RENEWABLE PARTNER PARTNERSHIP UNIT G16258108 3,115 103,000 SH   SOLE 0 103,000 0 0
BUNGE LIMITED COM G16962105 1,958 28,500 SH   SOLE 0 28,500 0 0
CATALYST BIOSCIENCES INC COM NEW 14888D208 2,652 246,000 SH   SOLE 0 246,000 0 0
CELGENE CORP COM 151020104 10,739 120,000 SH   SOLE 0 120,000 0 0
CERNER CORP COM 156782104 6,969 108,200 SH   SOLE 0 108,200 0 0
CIRRUS LOGIC INC COM 172755100 14,282 370,000 SH   SOLE 0 370,000 0 0
CLEARWAY ENERGY INC CL C 18539C204 1,174 61,000 SH   SOLE 0 61,000 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 32,540 2,207,610 SH   SOLE 0 2,207,610 0 0
COMPANHIA ENERGETICA DE MINA SP ADR N-V PFD 204409601 881 515,000 SH   SOLE 0 515,000 0 0
COVANTA HLDG CORP COM 22282E102 1,276 78,500 SH   SOLE 0 78,500 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107 3,530 123,225 SH   SOLE 0 123,225 0 0
CROWN CASTLE INTL CORP NEW COM 22822V101 33,956 305,000 SH   SOLE 0 305,000 0 0
CROWN CASTLE INTL CORP NEW 6.875% CON PFD A 22822V309 1,472 1,355 SH   SOLE 0 1,355 0 0
DELPHI TECHNOLOGIES PLC SHS G2709G107 1,652 52,666 SH   SOLE 0 52,666 0 0
DERMIRA INC COM 24983L104 3,641 334,000 SH   SOLE 0 334,000 0 0
DERMIRA INC NOTE 3.000% 5/1 24983LAB0 584 700,000 PRN   SOLE 0 700,000 0 0
EATON CORP PLC SHS G29183103 2,090 24,100 SH   SOLE 0 24,100 0 0
ENDOCYTE INC COM 29269A102 23,337 1,314,000 SH   SOLE 0 1,314,000 0 0
ENTASIS THERAPEUTICS HLDGS I COM 293614103 8,140 772,556 SH   SOLE 0 772,556 0 0
ERICSSON ADR B SEK 10 294821608 1,078 122,500 SH   SOLE 0 122,500 0 0
ESSA PHARMA INC COM NEW 29668H708 1,494 481,970 SH   SOLE 0 481,970 0 0
EXACT SCIENCES CORP COM 30063P105 10,339 131,000 SH   SOLE 0 131,000 0 0
EXTRA SPACE STORAGE INC COM 30225T102 6,931 80,000 SH   SOLE 0 80,000 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 6,078 741,175 SH   SOLE 0 741,175 0 0
FIRST HAWAIIAN INC COM 32051X108 2,526 93,000 SH   SOLE 0 93,000 0 0
FIVE9 INC COM 338307101 39,059 894,000 SH   SOLE 0 894,000 0 0
GALAPAGOS NV SPON ADR 36315X101 4,497 40,000 SH   SOLE 0 40,000 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 8,740 230,000 SH   SOLE 0 230,000 0 0
GRANITE PT MTG TR INC COM 38741L107 1,668 86,500 SH   SOLE 0 86,500 0 0
GTT COMMUNICATIONS INC COM 362393100 19,139 441,000 SH   SOLE 0 441,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 10,969 63,500 SH   SOLE 0 63,500 0 0
HANNON ARMSTRONG SUST INFR C COM 41068X100 16,145 752,000 SH   SOLE 0 752,000 0 0
HANNON ARMSTRONG SUST INFR C NOTE 4.125% 9/0 41068XAB6 1,361 1,394,000 PRN   SOLE 0 1,394,000 0 0
HERCULES CAPITAL INC DBCV 4.375% 2/0 427096AF9 194 200,000 PRN   SOLE 0 200,000 0 0
HONDA MOTOR LTD AMERN SHS 438128308 2,391 79,500 SH   SOLE 0 79,500 0 0
HUBSPOT INC COM 443573100 52,833 350,000 SH   SOLE 0 350,000 0 0
IMMUNOMEDICS INC COM 452907108 14,560 699,000 SH   SOLE 0 699,000 0 0
INCYTE CORP COM 45337C102 7,944 115,000 SH   SOLE 0 115,000 0 0
INFLARX NV COM N44821101 9,438 275,000 SH   SOLE 0 275,000 0 0
INGERSOLL-RAND PLC SHS G47791101 757 7,400 SH   SOLE 0 7,400 0 0
INPHI CORP COM 45772F107 21,079 555,000 SH   SOLE 0 555,000 0 0
INSTRUCTURE INC COM 45781U103 28,525 805,796 SH   SOLE 0 805,796 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 3,150 280,000 SH   SOLE 0 280,000 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 3,544 192,000 SH   SOLE 0 192,000 0 0
JOHNSON CTLS INTL PLC SHS G51502105 2,170 62,000 SH   SOLE 0 62,000 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 19,899 900,000 SH   SOLE 0 900,000 0 0
KAR AUCTION SVCS INC COM 48238T109 36,411 610,000 SH   SOLE 0 610,000 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101 8,135 319,000 SH   SOLE 0 319,000 0 0
LAM RESEARCH CORP COM 512807108 34,436 227,000 SH   SOLE 0 227,000 0 0
LEAR CORP COM NEW 521865204 26,680 184,000 SH   SOLE 0 184,000 0 0
LENNOX INTL INC COM 526107107 25,771 118,000 SH   SOLE 0 118,000 0 0
LEXINGTON REALTY TRUST COM 529043101 664 80,000 SH   SOLE 0 80,000 0 0
LIBERTY PPTY TR SH BEN INT 531172104 655 15,500 SH   SOLE 0 15,500 0 0
LOWES COS INC COM 548661107 64,873 565,000 SH   SOLE 0 565,000 0 0
LOXO ONCOLOGY INC COM 548862101 39,120 229,000 SH   SOLE 0 229,000 0 0
MACQUARIE INFRASTRUCTURE COR COM 55608B105 47,422 1,028,000 SH   SOLE 0 1,028,000 0 0
MACROGENICS INC COM 556099109 3,152 147,000 SH   SOLE 0 147,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 7,066 33,000 SH   SOLE 0 33,000 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 26,256 2,238,089 SH   SOLE 0 2,238,089 0 0
MAGNA INTL INC COM 559222401 32,238 613,700 SH   SOLE 0 613,700 0 0
MASONITE INTL CORP NEW COM 575385109 10,897 170,000 SH   SOLE 0 170,000 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 17,660 29,000 SH   SOLE 0 29,000 0 0
MILLER HERMAN INC COM 600544100 1,728 45,000 SH   SOLE 0 45,000 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 19,068 725,000 SH   SOLE 0 725,000 0 0
MYOKARDIA INC COM 62857M105 19,690 302,000 SH   SOLE 0 302,000 0 0
MYOVANT SCIENCES LTD COM G637AM102 56,153 2,115,000 SH   SOLE 0 2,115,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 19,180 156,000 SH   SOLE 0 156,000 0 0
NEXTERA ENERGY PARTNERS LP COM UNIT PART IN 65341B106 38,776 799,500 SH   SOLE 0 799,500 0 0
PALO ALTO NETWORKS INC COM 697435105 46,854 208,000 SH   SOLE 0 208,000 0 0
PATTERN ENERGY GROUP INC CL A 70338P100 21,171 1,065,500 SH   SOLE 0 1,065,500 0 0
PAYCOM SOFTWARE INC COM 70432V102 14,919 96,000 SH   SOLE 0 96,000 0 0
PROLOGIS INC COM 74340W103 1,017 15,000 SH   SOLE 0 15,000 0 0
PROOFPOINT INC COM 743424103 16,800 158,000 SH   SOLE 0 158,000 0 0
PTC THERAPEUTICS INC COM 69366J200 11,468 244,000 SH   SOLE 0 244,000 0 0
PUBLIC STORAGE COM 74460D109 403 2,000 SH   SOLE 0 2,000 0 0
RA PHARMACEUTICALS INC COM 74933V108 7,019 388,000 SH   SOLE 0 388,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107 9,293 23,000 SH   SOLE 0 23,000 0 0
REPLIGEN CORP COM 759916109 6,101 110,000 SH   SOLE 0 110,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 9,715 394,585 SH   SOLE 0 394,585 0 0
ROPER TECHNOLOGIES INC COM 776696106 25,770 87,000 SH   SOLE 0 87,000 0 0
SAGE THERAPEUTICS INC COM 78667J108 69,778 494,000 SH   SOLE 0 494,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 100,136 620,000 SH   SOLE 0 620,000 0 0
SEATTLE GENETICS INC COM 812578102 11,722 152,000 SH   SOLE 0 152,000 0 0
SENDGRID INC COM 816883102 72,427 1,968,653 SH   SOLE 0 1,968,653 0 0
SNAP ON INC COM 833034101 16,891 92,000 SH   SOLE 0 92,000 0 0
SOLID BIOSCIENCES INC COM 83422E105 18,872 400,000 SH   SOLE 0 400,000 0 0
SPECTRA ENERGY PARTNERS LP COM 84756N109 1,678 47,000 SH   SOLE 0 47,000 0 0
SPLUNK INC COM 848637104 54,772 453,000 SH   SOLE 0 453,000 0 0
STEEL DYNAMICS INC COM 858119100 34,073 754,000 SH   SOLE 0 754,000 0 0
STEMLINE THERAPEUTICS INC COM 85858C107 18,034 1,086,400 SH   SOLE 0 1,086,400 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 4,531 2,265,455 SH   SOLE 0 2,265,455 0 0
SUNOPTA INC COM 8676EP108 31,609 4,300,540 SH   SOLE 0 4,300,540 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 6,546 130,000 SH   SOLE 0 130,000 0 0
SUTRO BIOPHARMA INC COM 869367102 18,134 1,244,895 SH   SOLE 0 1,244,895 0 0
SYROS PHARMACEUTICALS INC COM 87184Q107 1,787 150,000 SH   SOLE 0 150,000 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100 2,628 59,500 SH   SOLE 0 59,500 0 0
TERRAFORM PWR INC COM CL A 88104R209 2,079 180,000 SH   SOLE 0 180,000 0 0
THE TRADE DESK INC COM CL A 88339J105 54,328 360,000 SH   SOLE 0 360,000 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 6,672 87,400 SH   SOLE 0 87,400 0 0
UNIQURE NV SHS N90064101 20,731 569,700 SH   SOLE 0 569,700 0 0
UROVANT SCIENCES LTD SHS G9381B108 7,138 594,816 SH   SOLE 0 594,816 0 0
VARONIS SYS INC COM 922280102 53,399 729,000 SH   SOLE 0 729,000 0 0
VBI VACCINES INC COM NEW 91822J103 4,477 1,850,000 SH   SOLE 0 1,850,000 0 0
VENTAS INC COM 92276F100 1,169 21,500 SH   SOLE 0 21,500 0 0
VERACYTE INC COM 92337F107 20,375 2,133,500 SH   SOLE 0 2,133,500 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 60,328 313,000 SH   SOLE 0 313,000 0 0
VIKING THERAPEUTICS INC COM 92686J106 13,762 790,000 SH   SOLE 0 790,000 0 0
VOYAGER THERAPEUTICS INC COM 92915B106 13,309 703,425 SH   SOLE 0 703,425 0 0
VULCAN MATLS CO COM 929160109 12,232 110,000 SH   SOLE 0 110,000 0 0
WABCO HLDGS INC COM 92927K102 30,145 255,600 SH   SOLE 0 255,600 0 0
WASTE CONNECTIONS INC COM 94106B101 41,241 517,000 SH   SOLE 0 517,000 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105 8,520 170,400 SH   SOLE 0 170,400 0 0
WAYFAIR INC CL A 94419L101 59,068 400,000 SH   SOLE 0 400,000 0 0
WELLTOWER INC COM 95040Q104 1,036 16,100 SH   SOLE 0 16,100 0 0
XENCOR INC COM 98401F105 8,885 228,000 SH   SOLE 0 228,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 4,158 315,000 SH   SOLE 0 315,000 0 0
XPO LOGISTICS INC COM 983793100 89,966 788,000 SH   SOLE 0 788,000 0 0
ZOGENIX INC COM NEW 98978L204 58,716 1,183,792 SH   SOLE 0 1,183,792 0 0