The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 318,835 708,917 SH   SOLE   708,917 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 34,964 1,684,180 SH   SOLE   1,684,180 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 37,694 1,381,759 SH   SOLE   1,381,759 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 30,854 1,853,101 SH   SOLE   1,853,101 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 166,840 1,200,201 SH   SOLE   1,200,201 0 0
ALIGN TECHNOLOGY INC COM 016255101 57,825 147,807 SH   SOLE   147,807 0 0
ALIMERA SCIENCES INC COM 016259103 2,954 3,013,793 SH   SOLE   3,013,793 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 67,610 3,380,506 SH   SOLE   3,380,506 0 0
AMICUS THERAPEUTICS INC COM 03152W109 76,967 6,366,147 SH   SOLE   6,366,147 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 247,218 2,549,431 SH   SOLE   2,549,431 0 0
CELGENE CORP COM 151020104 38,415 429,267 SH   SOLE   429,267 0 0
CLOVIS ONCOLOGY INC COM 189464100 153,342 5,221,026 SH   SOLE   5,221,026 0 0
CYTOKINETICS INC COM NEW 23282W605 1,218 123,686 SH   SOLE   123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 7,644 500,913 SH   SOLE   500,913 0 0
EPIZYME INC COM 29428V104 73,205 6,906,158 SH   SOLE   6,906,158 0 0
EXACT SCIENCES CORP COM 30063P105 24,727 313,320 SH   SOLE   313,320 0 0
GILEAD SCIENCES INC COM 375558103 13,581 175,900 SH   SOLE   175,900 0 0
HISTOGENICS CORP COM 43358V109 165 302,922 SH   SOLE   302,922 0 0
IDERA PHARMACEUTICALS INC COM PAR 45168K405 686 77,044 SH   SOLE   77,044 0 0
IMMUNOMEDICS INC COM 452907108 104,437 5,013,764 SH   SOLE   5,013,764 0 0
INSMED INC COM PAR $.01 457669307 148,764 7,357,283 SH   SOLE   7,357,283 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 79,416 4,663,324 SH   SOLE   4,663,324 0 0
MELINTA THERAPEUTICS INC COM 58549G100 200 50,689 SH   SOLE   50,689 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 48,222 1,833,532 SH   SOLE   1,833,532 0 0
PROTHENA CORP PLC SHS G72800108 14,431 1,103,325 SH   SOLE   1,103,325 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 12,731 3,966,087 SH   SOLE   3,966,087 0 0
SAGE THERAPEUTICS INC COM 78667J108 118,703 840,372 SH   SOLE   840,372 0 0
SHIRE PLC SPONSORED ADR 82481R106 34,938 192,738 SH   SOLE   192,738 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 689 247,000 SH   SOLE   247,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 169,035 3,521,565 SH   SOLE   3,521,565 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 2,325 1,162,473 SH   SOLE   1,162,473 0 0
TREVENA INC COM 89532E109 724 341,300 SH   SOLE   341,300 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 207,835 1,625,234 SH   SOLE   1,625,234 0 0
VANDA PHARMACEUTICALS INC COM 921659108 95,373 4,155,670 SH   SOLE   4,155,670 0 0
WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 80,025 2,757,587 SH   SOLE   2,757,587 0 0
ZOGENIX INC COM NEW 98978L204 1,463 29,500 SH   SOLE   29,500 0 0