The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
58 COM INC SPON ADR REP A 31680Q104 67,299 914,389 SH   SOLE 914,389 0 0
ACCELERON PHARMA INC COM 00434H108 2,947 51,489 SH   SOLE 51,489 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 1,951 31,700 SH   SOLE 31,700 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 2,329 30,200 SH   SOLE 30,200 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 139,692 847,854 SH   SOLE 847,854 0 0
ALLY FINL INC COM 02005N100 105,194 3,977,100 SH   SOLE 3,517,800 0 459,300
ALPHABET INC CAP STK CL A 02079K305 202,430 167,702 SH   SOLE 153,412 0 14,290
ALPHABET INC CAP STK CL C 02079K107 177,760 148,944 SH   SOLE 133,858 0 15,086
ANALOG DEVICES INC COM 032654105 601 6,500 SH   SOLE 6,500 0 0
APPLE INC COM 037833100 2,867 12,700 SH   SOLE 12,700 0 0
ARCUS BIOSCIENCES INC COM 03969F109 1,336 95,841 SH   SOLE 95,841 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 2,270 284,495 SH   SOLE 284,495 0 0
BAIDU INC SPON ADR REP A 056752108 96,382 421,469 SH   SOLE 421,469 0 0
BARRICK GOLD CORP COM 067901108 620 56,000 SH   SOLE 56,000 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 1,340 13,820 SH   SOLE 13,820 0 0
BITAUTO HLDGS LTD SPONSORED ADS 091727107 63,001 2,739,192 SH   SOLE 2,577,092 0 162,100
CALLAWAY GOLF CO COM 131193104 13,914 572,818 SH   SOLE 572,818 0 0
CARNIVAL CORP UNIT 99/99/9999 143658300 1,866 29,260 SH   SOLE 29,260 0 0
CARVANA CO CL A 146869102 278 4,700 SH   SOLE 4,700 0 0
CENTURYLINK INC COM 156700106 8,882 418,951 SH   SOLE 418,951 0 0
CF INDS HLDGS INC COM 125269100 145,455 2,671,833 SH   SOLE 2,277,433 0 394,400
CISCO SYS INC COM 17275R102 1,737 35,700 SH   SOLE 35,700 0 0
COHERUS BIOSCIENCES INC COM 19249H103 2,261 137,000 SH   SOLE 137,000 0 0
DENTSPLY SIRONA INC COM 24906P109 868 23,000 SH   SOLE 23,000 0 0
DERMIRA INC COM 24983L104 1,268 116,325 SH   SOLE 116,325 0 0
EBAY INC COM 278642103 1,014 30,700 SH   SOLE 30,700 0 0
EQUIFAX INC COM 294429105 91,099 697,703 SH   SOLE 622,703 0 75,000
FACEBOOK INC CL A 30303M102 291,002 1,769,440 SH   SOLE 1,593,040 0 176,400
FIVE PRIME THERAPEUTICS INC COM 33830X104 1,692 121,576 SH   SOLE 121,576 0 0
GILEAD SCIENCES INC COM 375558103 155,889 2,019,030 SH   SOLE 1,835,030 0 184,000
GOLDEN OCEAN GROUP LTD SHS NEW G39637205 159,300 2,000,000 SH   SOLE 2,000,000 0 0
HANESBRANDS INC COM 410345102 24,419 1,324,986 SH   SOLE 1,324,986 0 0
ICON PLC SHS G4705A100 2,675 17,400 SH   SOLE 17,400 0 0
IHS MARKIT LTD SHS G47567105 27,277 505,500 SH   SOLE 505,500 0 0
INCYTE CORP COM 45337C102 1,448 20,964 SH   SOLE 20,964 0 0
INFINITY PHARMACEUTICALS INC COM 45665G303 2,685 990,748 SH   SOLE 990,748 0 0
INTEL CORP COM 458140100 175,419 3,709,431 SH   SOLE 3,419,031 0 290,400
INTELLIA THERAPEUTICS INC COM 45826J105 1,574 55,000 SH   SOLE 55,000 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 1,266 68,600 SH   SOLE 68,600 0 0
JD COM INC SPON ADR CL A 47215P106 934 35,800 SH   SOLE 35,800 0 0
JOHNSON & JOHNSON COM 478160104 4,532 32,800 SH   SOLE 32,800 0 0
LAM RESEARCH CORP COM 512807108 1,292 8,520 SH   SOLE 8,520 0 0
LIBERTY GLOBAL PLC SHS CL A G5480U104 428 14,800 SH   SOLE 14,800 0 0
LIVANOVA PLC SHS G5509L101 2,688 21,682 SH   SOLE 21,682 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 885 73,700 SH   SOLE 73,700 0 0
MELCO RESORT ENTERTAINMENT L ADR 585464100 6,668 315,253 SH   SOLE 315,253 0 0
MERCK & CO INC COM 58933Y105 1,334 18,800 SH   SOLE 18,800 0 0
MERUS N V COM N5749R100 2,018 102,219 SH   SOLE 102,219 0 0
MICROCHIP TECHNOLOGY INC COM 595017104 102,981 1,305,040 SH   SOLE 1,176,173 0 128,867
MICRON TECHNOLOGY INC COM 595112103 731 16,152 SH   SOLE 16,152 0 0
MICROSOFT CORP COM 594918104 2,653 23,200 SH   SOLE 23,200 0 0
MOLSON COORS BREWING CO CL B 60871R209 8,542 138,900 SH   SOLE 138,900 0 0
MOMO INC ADR 60879B107 18,501 422,400 SH   SOLE 422,400 0 0
MYOVANT SCIENCES LTD COM G637AM102 1,896 71,400 SH   SOLE 71,400 0 0
NANOSTRING TECHNOLOGIES INC COM 63009R109 4,145 232,500 SH   SOLE 232,500 0 0
NETGEAR INC COM 64111Q104 446 7,100 SH   SOLE 7,100 0 0
NIELSEN HLDGS PLC SHS EUR G6518L108 6,867 248,258 SH   SOLE 248,258 0 0
NOMAD FOODS LTD USD ORD SHS G6564A105 15,604 770,200 SH   SOLE 770,200 0 0
ORACLE CORP COM 68389X105 2,140 41,500 SH   SOLE 41,500 0 0
PAYPAL HLDGS INC COM 70450Y103 54,682 622,521 SH   SOLE 622,521 0 0
PEABODY ENERGY CORP NEW COM 704551100 86,752 2,434,111 SH   SOLE 2,236,019 0 198,092
PERKINELMER INC COM 714046109 3,207 32,971 SH   SOLE 32,971 0 0
PERRIGO CO PLC SHS G97822103 1,324 18,700 SH   SOLE 18,700 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 1,076 192,100 SH   SOLE 192,100 0 0
PROTHENA CORP PLC SHS G72800108 1,768 135,200 SH   SOLE 135,200 0 0
QIAGEN NV SHS NEW N72482123 17,617 540,407 SH   SOLE 540,407 0 0
QIWI PLC SPON ADR REP B 74735M108 27,835 2,113,485 SH   SOLE 1,946,910 0 166,575
QUANTERIX CORP COM 74766Q101 3,749 175,000 SH   SOLE 175,000 0 0
SANGAMO THERAPEUTICS INC COM 800677106 897 52,900 SH   SOLE 52,900 0 0
SEATTLE GENETICS INC COM 812578102 2,661 34,500 SH   SOLE 34,500 0 0
SINA CORP ORD G81477104 240,732 3,464,772 SH   SOLE 3,081,754 0 383,018
SKYWORKS SOLUTIONS INC COM 83088M102 101,483 1,118,760 SH   SOLE 994,460 0 124,300
STAMPS COM INC COM NEW 852857200 588 2,600 SH   SOLE 2,600 0 0
STARS GROUP INC COM 85570W100 16,671 669,529 SH   SOLE 669,529 0 0
SUNCOR ENERGY INC NEW COM 867224107 401 10,360 SH   SOLE 10,360 0 0
TECHNIPFMC PLC COM G87110105 264,225 8,455,185 SH   SOLE 7,301,885 0 1,153,300
TESARO INC COM 881569107 671 17,200 SH   SOLE 17,200 0 0
TRANSOCEAN LTD REG SHS H8817H100 202,176 14,492,927 SH   SOLE 13,056,677 0 1,436,250
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 1,007 175,339 SH   SOLE 175,339 0 0
TWILIO INC CL A 90138F102 673 7,800 SH   SOLE 7,800 0 0
UNITED TECHNOLOGIES CORP COM 913017109 1,118 8,000 SH   SOLE 8,000 0 0
UNUM THERAPEUTICS INC COM 903214104 1,810 175,700 SH   SOLE 175,700 0 0
VERISIGN INC COM 92343E102 897 5,600 SH   SOLE 5,600 0 0
WARRIOR MET COAL INC COM 93627C101 43,421 1,605,800 SH   SOLE 1,472,500 0 133,300
WAVE LIFE SCIENCES LTD SHS Y95308105 1,610 32,200 SH   SOLE 32,200 0 0
WEIBO CORP SPONSORED ADR 948596101 102,569 1,402,555 SH   SOLE 1,402,555 0 0
XILINX INC COM 983919101 898 11,200 SH   SOLE 11,200 0 0
YY INC ADS REPCOM CLA 98426T106 20,202 269,652 SH   SOLE 269,652 0 0
ZAI LAB LTD ADR 98887Q104 1,641 84,250 SH   SOLE 84,250 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADR 98980A105 156,560 9,448,425 SH   SOLE 8,488,260 0 960,165