The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Assembly Biosciences Inc | COM | 045396108 | 15,532 | 686,644 | SH | SOLE | 1 | 686,644 | 0 | 0 | |
| FLUIDIGM CORP DEL | COM | 34385P108 | 7,622 | 884,235 | SH | SOLE | 1 | 884,235 | 0 | 0 | |
| Agenus Inc | COM NEW | 00847G705 | 24,122 | 10,135,119 | SH | SOLE | 1 | 10,135,119 | 0 | 0 | |
| Arbutus Biopharma Corp | COM | 03879J100 | 16,606 | 4,335,746 | SH | SOLE | 1 | 4,335,746 | 0 | 0 | |
| PTC Therapeutics Inc | COM | 69366J200 | 65,975 | 1,922,346 | SH | SOLE | 1 | 1,922,346 | 0 | 0 | |
| SAGE Therapeutics Inc | COM | 78667J108 | 15,900 | 165,990 | SH | SOLE | 1 | 165,990 | 0 | 0 | |
| PROQR THRAPEUTICS N V | SHS EURO | N71542109 | 7,072 | 448,141 | SH | SOLE | 1 | 448,141 | 0 | 0 | |
| Cytomx Therapeutics Inc | COM | 23284F105 | 13,720 | 908,586 | SH | SOLE | 1 | 908,586 | 0 | 0 | |
| Viewray Inc | COM | 92672L107 | 8,280 | 1,364,156 | SH | SOLE | 1 | 1,364,156 | 0 | 0 | |
| Orthopediatrics Corp | COM | 68752L100 | 7,848 | 225,000 | SH | SOLE | 1 | 225,000 | 0 | 0 | |
| Optinose Inc | COM | 68404V100 | 493 | 79,466 | SH | SOLE | 1 | 79,466 | 0 | 0 | |
| Myokardia Inc | COM | 62857M105 | 14,409 | 294,898 | SH | SOLE | 1 | 294,898 | 0 | 0 | |
| PROTEOSTASIS THERAPEUTICS IN | COM | 74373B109 | 1,016 | 313,466 | SH | SOLE | 1 | 313,466 | 0 | 0 | |
| Mirati Therapeutics Inc | COM | 60468T105 | 1,644 | 38,765 | SH | SOLE | 1 | 38,765 | 0 | 0 | |
| CareDx Inc | COM | 14167L103 | 8,238 | 327,703 | SH | SOLE | 1 | 327,703 | 0 | 0 | |
| Adverum Biotechnologies Inc | COM | 00773U108 | 19,709 | 6,256,840 | SH | SOLE | 1 | 6,256,840 | 0 | 0 | |
| Rocket Pharmaceuticals Inc | COM | 77313F106 | 235,848 | 16,037,486 | SH | SOLE | 1 | 16,037,486 | 0 | 0 | |
| VIVEVE MED INC | COM NEW | 92852W204 | 4,705 | 4,480,565 | SH | SOLE | 1 | 4,480,565 | 0 | 0 | |
| Regenxbio Inc | COM | 75901B107 | 44,058 | 1,050,245 | SH | SOLE | 1 | 1,050,245 | 0 | 0 | |
| LivaNova PLC | SHS | G5509L101 | 40,525 | 443,036 | SH | SOLE | 1 | 443,036 | 0 | 0 | |
| SI BONE INC | COM | 825704109 | 16,802 | 804,327 | SH | SOLE | 1 | 804,327 | 0 | 0 | |
| AXONICS MODULATION TECH INC | COM | 05465P101 | 16,551 | 1,095,396 | SH | SOLE | 1 | 1,095,396 | 0 | 0 | |
| ARGENX SE | SPONSORED ADR | 04016X101 | 2,765 | 28,777 | SH | SOLE | 1 | 28,777 | 0 | 0 | |
| Odonate Therapeutics Inc | COM | 676079106 | 4,390 | 311,790 | SH | SOLE | 1 | 311,790 | 0 | 0 | |
| Solid Biosciences Inc | COM | 83422E105 | 3,578 | 133,506 | SH | SOLE | 1 | 133,506 | 0 | 0 | |
| MOTUS GI HLDGS INC | COM | 62014P108 | 1,429 | 459,478 | SH | SOLE | 1 | 459,478 | 0 | 0 | |
| Homology Medicines Inc | COM | 438083107 | 36,525 | 1,633,491 | SH | SOLE | 1 | 1,633,491 | 0 | 0 | |
| ELECTROCORE INC | COM | 28531P103 | 3,243 | 518,010 | SH | SOLE | 1 | 518,010 | 0 | 0 | |
| Neuronetics Inc | COM | 64131A105 | 3,246 | 167,728 | SH | SOLE | 1 | 167,728 | 0 | 0 | |
| ESTABLISHMENT LABS HLDGS INC | COM | G31249108 | 22,740 | 848,058 | SH | SOLE | 1 | 848,058 | 0 | 0 | |
| RA MED SYS INC | COM | 74933X104 | 487 | 61,281 | SH | SOLE | 1 | 61,281 | 0 | 0 | |
| La Jolla Pharmaceutical Co | COM PAR $.0001 2 | 503459604 | 2,528 | 268,036 | SH | SOLE | 1 | 268,036 | 0 | 0 | |
| Dicerna Pharmaceuticals Inc | COM | 253031108 | 63,147 | 5,907,088 | SH | SOLE | 1 | 5,907,088 | 0 | 0 | |
| Uniqure NV | SHS | N90064101 | 13,310 | 461,837 | SH | SOLE | 1 | 461,837 | 0 | 0 | |
| Concert Pharmaceuticals Inc | COM | 206022105 | 9,900 | 788,877 | SH | SOLE | 1 | 788,877 | 0 | 0 | |
| BRISTOL MYERS SQUIBB CO | COM | 110122108 | 49,422 | 950,780 | SH | SOLE | 1 | 950,780 | 0 | 0 | |
| Vericel Corp | COM | 92346J108 | 39,831 | 2,289,134 | SH | SOLE | 1 | 2,289,134 | 0 | 0 | |
| Alnylam Pharmaceuticals Inc | COM | 02043Q107 | 32,044 | 439,498 | SH | SOLE | 1 | 439,498 | 0 | 0 | |
| Masimo Corp | COM | 574795100 | 36,744 | 342,221 | SH | SOLE | 1 | 342,221 | 0 | 0 | |
| ACHILLION PHARMACEUTICALS IN | COM | 00448Q201 | 21,862 | 13,749,383 | SH | SOLE | 1 | 13,749,383 | 0 | 0 | |
| Johnson & Johnson | COM | 478160104 | 10,399 | 80,583 | SH | SOLE | 1 | 80,583 | 0 | 0 | |
| ARROWHEAD PHARMACEUTICALS IN | COM | 04280A100 | 66,027 | 5,316,156 | SH | SOLE | 1 | 5,316,156 | 0 | 0 | |
| Sarepta Therapeutics Inc | COM | 803607100 | 39,932 | 365,911 | SH | SOLE | 1 | 365,911 | 0 | 0 | |
| CHARDAN HEALTHCARE ACQUISITI | UNIT 12/13/2023 | 15957A207 | 6,042 | 600,000 | SH | SOLE | 1 | 600,000 | 0 | 0 | |
| LIVANOVA PLC | PUT | G5509L101 | 723 | 7,900 | SH | Put | SOLE | 1 | 7,900 | 0 | 0 |
| Principia Biopharma Inc | COM | 74257L108 | 14,162 | 555,948 | SH | SOLE | 1 | 555,948 | 0 | 0 | |
| Vivus Inc 4.5 05/01/2020 | NOTE 4.500% 5/0 | 928551AA8 | 3,240 | 4,000,000 | SH | SOLE | 1 | 4,000,000 | 0 | 0 | |