The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 199,529 698,654 SH   SOLE   698,654 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 60,370 2,248,403 SH   SOLE   2,248,403 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 83,789 3,748,939 SH   SOLE   3,748,939 0 0
ALDER BIOPHARMACEUTICALS INC COM 014339105 25,411 1,861,630 SH   SOLE   1,861,630 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 166,140 1,229,030 SH   SOLE   1,229,030 0 0
ALIGN TECHNOLOGY INC COM 016255101 47,030 165,405 SH   SOLE   165,405 0 0
ALIMERA SCIENCES INC COM 016259103 3,195 3,013,793 SH   SOLE   3,013,793 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 44,066 3,421,306 SH   SOLE   3,421,306 0 0
AMICUS THERAPEUTICS INC COM 03152W109 103,630 7,619,833 SH   SOLE   7,619,833 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 234,643 2,641,485 SH   SOLE   2,641,485 0 0
CELGENE CORP COM 151020104 25,126 266,333 SH   SOLE   266,333 0 0
CLOVIS ONCOLOGY INC COM 189464100 130,040 5,239,304 SH   SOLE   5,239,304 0 0
CYTOKINETICS INC COM NEW 23282W605 1,001 123,686 SH   SOLE   123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 7,338 500,913 SH   SOLE   500,913 0 0
EPIZYME INC COM 29428V104 85,926 6,935,074 SH   SOLE   6,935,074 0 0
EXACT SCIENCES CORP COM 30063P105 27,276 314,889 SH   SOLE   314,889 0 0
GILEAD SCIENCES INC COM 375558103 11,435 175,900 SH   SOLE   175,900 0 0
HISTOGENICS CORP COM 43358V109 35 302,922 SH   SOLE   302,922 0 0
IDERA PHARMACEUTICALS INC COM PAR 45168K405 196 77,044 SH   SOLE   77,044 0 0
IMMUNOMEDICS INC COM 452907108 122,590 6,381,555 SH   SOLE   6,381,555 0 0
INSMED INC COM PAR $.01 457669307 222,491 7,653,617 SH   SOLE   7,653,617 0 0
KALEIDO BIOSCIENCES INC COM 483347100 12,567 866,666 SH   SOLE   866,666 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 30,732 5,262,263 SH   SOLE   5,262,263 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 477 114,221 SH   SOLE   114,221 0 0
MELINTA THERAPEUTICS INC COM NEW 58549G209 36 10,137 SH   SOLE   10,137 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 26,759 1,841,613 SH   SOLE   1,841,613 0 0
PROTHENA CORP PLC SHS G72800108 13,446 1,108,510 SH   SOLE   1,108,510 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 45,802 1,180,780 SH   SOLE   1,180,780 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 10,244 3,985,945 SH   SOLE   3,985,945 0 0
SAGE THERAPEUTICS INC COM 78667J108 136,414 857,681 SH   SOLE   857,681 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 245 247,000 SH   SOLE   247,000 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 144,244 4,218,902 SH   SOLE   4,218,902 0 0
SUNESIS PHARMACEUTICALS INC COM PAR 867328700 1,412 1,162,473 SH   SOLE   1,162,473 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 191,551 1,632,025 SH   SOLE   1,632,025 0 0
VANDA PHARMACEUTICALS INC COM 921659108 93,013 5,055,050 SH   SOLE   5,055,050 0 0
WRIGHT MED GROUP N V ORD SHS N96617118 87,160 2,771,394 SH   SOLE   2,771,394 0 0
ZOGENIX INC COM NEW 98978L204 1,623 29,500 SH   SOLE   29,500 0 0