The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| 2U | COM | 90214J101 | 27,908 | 741,440 | SH | DFND | 1 | 741,440 | 0 | 0 | |
| 2U | COM | 90214J101 | 29,778 | 791,120 | SH | DFND | 2 | 22,609 | 0 | 768,511 | |
| 2U | COM | 90214J101 | 306 | 8,139 | SH | DFND | 3 | 8,139 | 0 | 0 | |
| 2U | COM | 90214J101 | 9,686 | 257,335 | SH | SOLE | 0 | 257,335 | 0 | 0 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 41,836 | 672,923 | SH | DFND | 1 | 672,923 | 0 | 0 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 133,948 | 2,154,550 | SH | DFND | 2 | 1,626,675 | 0 | 527,875 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 30,938 | 497,638 | SH | DFND | 3 | 347,144 | 0 | 150,494 | |
| 58.Com Inc Adr | SPON ADR REP A | 31680Q104 | 88,554 | 1,424,381 | SH | SOLE | 0 | 1,378,847 | 0 | 45,534 | |
| AJ Gallagher & Co | COM | 363576109 | 96,473 | 1,101,411 | SH | DFND | 1 | 1,101,411 | 0 | 0 | |
| AJ Gallagher & Co | COM | 363576109 | 281,317 | 3,211,746 | SH | DFND | 2 | 2,422,234 | 0 | 789,512 | |
| AJ Gallagher & Co | COM | 363576109 | 62,413 | 712,559 | SH | DFND | 3 | 499,106 | 0 | 213,453 | |
| AJ Gallagher & Co | COM | 363576109 | 188,897 | 2,156,609 | SH | SOLE | 0 | 2,090,212 | 0 | 66,397 | |
| Abiomed | COM | 003654100 | 170,854 | 655,894 | SH | DFND | 1 | 655,894 | 0 | 0 | |
| Abiomed | COM | 003654100 | 258,515 | 992,417 | SH | DFND | 2 | 409,578 | 0 | 582,839 | |
| Abiomed | COM | 003654100 | 29,912 | 114,829 | SH | DFND | 3 | 81,330 | 0 | 33,499 | |
| Abiomed | COM | 003654100 | 118,782 | 455,996 | SH | SOLE | 0 | 447,515 | 0 | 8,481 | |
| Acacia Reasearch Corp | ACACIA TCH COM | 003881307 | 425 | 143,640 | SH | DFND | 1 | 143,640 | 0 | 0 | |
| Acacia Reasearch Corp | ACACIA TCH COM | 003881307 | 658 | 222,180 | SH | SOLE | 0 | 222,180 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 32,044 | 678,903 | SH | DFND | 1 | 678,903 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 47,843 | 1,013,629 | SH | DFND | 2 | 345,597 | 0 | 668,032 | |
| Activision Blizzard Inc | COM | 00507V109 | 348 | 7,379 | SH | DFND | 3 | 7,379 | 0 | 0 | |
| Activision Blizzard Inc | COM | 00507V109 | 9,420 | 199,578 | SH | SOLE | 0 | 199,578 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 8,184 | 2,035,855 | SH | DFND | 1 | 2,035,855 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 4,521 | 1,124,712 | SH | DFND | 2 | 366,703 | 0 | 758,009 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 1,136 | 282,576 | SH | DFND | 3 | 282,576 | 0 | 0 | |
| Adaptimmune Therapeutics ADR | SPONDS ADR | 00653A107 | 2,817 | 700,697 | SH | SOLE | 0 | 700,697 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 3,051 | 1,980,937 | SH | DFND | 1 | 1,980,937 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 1,876 | 1,218,384 | SH | DFND | 2 | 393,696 | 0 | 824,688 | |
| Aduro Biotechnology | COM | 00739L101 | 441 | 286,110 | SH | DFND | 3 | 286,110 | 0 | 0 | |
| Aduro Biotechnology | COM | 00739L101 | 901 | 585,293 | SH | SOLE | 0 | 585,293 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 16,447 | 289,717 | SH | DFND | 1 | 289,717 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 12,462 | 219,516 | SH | DFND | 2 | 70,783 | 0 | 148,733 | |
| Aerovironment | COM | 008073108 | 3,078 | 54,227 | SH | DFND | 3 | 54,227 | 0 | 0 | |
| Aerovironment | COM | 008073108 | 12,522 | 220,567 | SH | SOLE | 0 | 220,567 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 22,825 | 457,608 | SH | DFND | 1 | 457,608 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 23,316 | 467,439 | SH | DFND | 2 | 13,817 | 0 | 453,622 | |
| Agios Pharmaceuticals | COM | 00847X104 | 346 | 6,934 | SH | DFND | 3 | 6,934 | 0 | 0 | |
| Agios Pharmaceuticals | COM | 00847X104 | 7,375 | 147,848 | SH | SOLE | 0 | 147,848 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 32,173 | 456,942 | SH | DFND | 1 | 456,942 | 0 | 0 | |
| Albemarle Corp | COM | 012653101 | 80,222 | 1,139,349 | SH | DFND | 2 | 865,927 | 0 | 273,422 | |
| Albemarle Corp | COM | 012653101 | 17,055 | 242,225 | SH | DFND | 3 | 171,174 | 0 | 71,051 | |
| Albemarle Corp | COM | 012653101 | 59,651 | 847,197 | SH | SOLE | 0 | 824,979 | 0 | 22,218 | |
| Alector Inc | COM | 014442107 | 42 | 2,185 | SH | DFND | 3 | 2,185 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 623,747 | 3,681,009 | SH | DFND | 1 | 3,681,009 | 0 | 0 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 5,451,070 | 32,169,195 | SH | DFND | 2 | 12,715,534 | 0 | 19,453,661 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 429,932 | 2,537,223 | SH | DFND | 3 | 829,571 | 0 | 1,707,652 | |
| Alibaba Group Holding Sponsored ADR | SPONSORED ADS | 01609W102 | 1,637,332 | 9,662,629 | SH | SOLE | 0 | 8,075,137 | 0 | 1,587,492 | |
| Align Technology Inc | COM | 016255101 | 13,973 | 51,052 | SH | DFND | 2 | 51,052 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 113,752 | 1,567,694 | SH | DFND | 1 | 1,567,694 | 0 | 0 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 185,540 | 2,557,062 | SH | DFND | 2 | 1,308,508 | 0 | 1,248,554 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 30,362 | 418,434 | SH | DFND | 3 | 334,924 | 0 | 83,510 | |
| Alnylam Pharmaceuticals | COM | 02043Q107 | 121,196 | 1,670,280 | SH | SOLE | 0 | 1,645,094 | 0 | 25,186 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 19,651 | 18,148 | SH | DFND | 1 | 18,148 | 0 | 0 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 31,838 | 29,403 | SH | DFND | 2 | 26,399 | 0 | 3,004 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 4,781 | 4,415 | SH | DFND | 3 | 2,780 | 0 | 1,635 | |
| Alphabet Inc Class A | CAP STK CL A | 02079K305 | 77,365 | 71,449 | SH | SOLE | 0 | 71,449 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 400,586 | 370,601 | SH | DFND | 1 | 370,601 | 0 | 0 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 1,320,353 | 1,221,520 | SH | DFND | 2 | 558,480 | 0 | 663,040 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 131,985 | 122,105 | SH | DFND | 3 | 76,937 | 0 | 45,168 | |
| Alphabet Inc Class C | CAP STK CL C | 02079K107 | 668,945 | 618,872 | SH | SOLE | 0 | 490,403 | 0 | 128,469 | |
| Amazon.Com | COM | 023135106 | 971,930 | 513,263 | SH | DFND | 1 | 513,263 | 0 | 0 | |
| Amazon.Com | COM | 023135106 | 4,792,081 | 2,530,632 | SH | DFND | 2 | 768,906 | 0 | 1,761,726 | |
| Amazon.Com | COM | 023135106 | 285,781 | 150,917 | SH | DFND | 3 | 91,589 | 0 | 59,328 | |
| Amazon.Com | COM | 023135106 | 2,376,562 | 1,255,030 | SH | SOLE | 0 | 1,064,267 | 0 | 190,763 | |
| Ambarella | SHS | G037AX101 | 6,509 | 147,500 | SH | DFND | 1 | 147,500 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 5,240 | 118,734 | SH | DFND | 2 | 38,117 | 0 | 80,617 | |
| Ambarella | SHS | G037AX101 | 1,340 | 30,365 | SH | DFND | 3 | 30,365 | 0 | 0 | |
| Ambarella | SHS | G037AX101 | 4,307 | 97,605 | SH | SOLE | 0 | 97,605 | 0 | 0 | |
| Ameren | COM | 023608102 | 25,598 | 340,813 | SH | DFND | 1 | 340,813 | 0 | 0 | |
| Ameren | COM | 023608102 | 35 | 470 | SH | DFND | 2 | 470 | 0 | 0 | |
| Ameren | COM | 023608102 | 1,138 | 15,145 | SH | DFND | 3 | 15,145 | 0 | 0 | |
| American Express | COM | 025816109 | 2,367 | 19,175 | SH | DFND | 1 | 19,175 | 0 | 0 | |
| American Express | COM | 025816109 | 20,471 | 165,836 | SH | DFND | 2 | 165,836 | 0 | 0 | |
| American Express | COM | 025816109 | 1,336 | 10,821 | SH | DFND | 3 | 5,928 | 0 | 4,893 | |
| American Express | COM | 025816109 | 2,420 | 19,607 | SH | SOLE | 0 | 19,607 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 15,922 | 141,063 | SH | DFND | 1 | 141,063 | 0 | 0 | |
| Analog Devices | COM | 032654105 | 1,014 | 8,987 | SH | DFND | 2 | 0 | 0 | 8,987 | |
| Analog Devices | COM | 032654105 | 15,543 | 137,705 | SH | SOLE | 0 | 137,705 | 0 | 0 | |
| Anaplan Inc Common | COM | 03272L108 | 94,462 | 1,871,644 | SH | SOLE | 0 | 1,871,644 | 0 | 0 | |
| Annaly Capital Man. | COM | 035710409 | 162 | 17,762 | SH | DFND | 1 | 17,762 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 174,145 | 617,077 | SH | DFND | 1 | 617,077 | 0 | 0 | |
| Anthem Inc | COM | 036752103 | 568,054 | 2,012,878 | SH | DFND | 2 | 1,514,835 | 0 | 498,043 | |
| Anthem Inc | COM | 036752103 | 127,570 | 452,039 | SH | DFND | 3 | 315,763 | 0 | 136,276 | |
| Anthem Inc | COM | 036752103 | 374,656 | 1,327,578 | SH | SOLE | 0 | 1,285,559 | 0 | 42,019 | |
| Apache Corp | COM | 037411105 | 102,112 | 3,524,737 | SH | DFND | 1 | 3,524,737 | 0 | 0 | |
| Apache Corp | COM | 037411105 | 314,653 | 10,861,336 | SH | DFND | 2 | 8,156,841 | 0 | 2,704,495 | |
| Apache Corp | COM | 037411105 | 61,144 | 2,110,610 | SH | DFND | 3 | 1,376,984 | 0 | 733,626 | |
| Apache Corp | COM | 037411105 | 208,360 | 7,192,284 | SH | SOLE | 0 | 6,968,960 | 0 | 223,324 | |
| Apollo Commercial Real Estate Finance REIT | COM | 03762U105 | 223 | 12,100 | SH | DFND | 1 | 12,100 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 13,831 | 383,439 | SH | DFND | 1 | 383,439 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 10,233 | 283,700 | SH | DFND | 2 | 91,157 | 0 | 192,543 | |
| Appian Corp | CL A | 03782L101 | 2,523 | 69,936 | SH | DFND | 3 | 69,936 | 0 | 0 | |
| Appian Corp | CL A | 03782L101 | 6,869 | 190,433 | SH | SOLE | 0 | 190,433 | 0 | 0 | |
| Apple | COM | 037833100 | 10,124 | 51,154 | SH | DFND | 1 | 51,154 | 0 | 0 | |
| Apple | COM | 037833100 | 714 | 3,606 | SH | DFND | 2 | 0 | 0 | 3,606 | |
| Apple | COM | 037833100 | 9,749 | 49,258 | SH | SOLE | 0 | 49,258 | 0 | 0 | |
| Aslan Pharmaceuticals ADR | ADS | 04522R101 | 834 | 271,727 | SH | DFND | 1 | 271,727 | 0 | 0 | |
| Aslan Pharmaceuticals ADR | ADS | 04522R101 | 483 | 157,248 | SH | SOLE | 0 | 157,248 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 103,956 | 794,524 | SH | DFND | 1 | 794,524 | 0 | 0 | |
| Atlassian Corp Plc | CL A | G06242104 | 611,485 | 4,673,533 | SH | DFND | 2 | 1,720,272 | 0 | 2,953,261 | |
| Atlassian Corp Plc | CL A | G06242104 | 31,681 | 242,137 | SH | DFND | 3 | 107,466 | 0 | 134,671 | |
| Atlassian Corp Plc | CL A | G06242104 | 212,441 | 1,623,673 | SH | SOLE | 0 | 791,299 | 0 | 832,374 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 39,734 | 464,074 | SH | DFND | 1 | 464,074 | 0 | 0 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 129,256 | 1,509,643 | SH | DFND | 2 | 1,141,741 | 0 | 367,902 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 29,559 | 345,235 | SH | DFND | 3 | 242,106 | 0 | 103,129 | |
| Autohome Inc - ADR | SP ADR RP CL A | 05278C107 | 89,600 | 1,046,483 | SH | SOLE | 0 | 1,014,844 | 0 | 31,639 | |
| Avangrid | COM | 05351W103 | 23,589 | 467,100 | SH | DFND | 1 | 467,100 | 0 | 0 | |
| Avangrid | COM | 05351W103 | 33 | 650 | SH | DFND | 2 | 650 | 0 | 0 | |
| Avangrid | COM | 05351W103 | 1,129 | 22,360 | SH | DFND | 3 | 22,360 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 7,110 | 359,100 | SH | DFND | 1 | 359,100 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 7,086 | 357,900 | SH | DFND | 2 | 115,000 | 0 | 242,900 | |
| Axogen Inc | COM | 05463X106 | 1,750 | 88,400 | SH | DFND | 3 | 88,400 | 0 | 0 | |
| Axogen Inc | COM | 05463X106 | 3,358 | 169,600 | SH | SOLE | 0 | 169,600 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 45,123 | 702,741 | SH | DFND | 1 | 702,741 | 0 | 0 | |
| Axon Enterprise Inc | COM | 05464C101 | 124,343 | 1,936,502 | SH | DFND | 2 | 1,380,316 | 0 | 556,186 | |
| Axon Enterprise Inc | COM | 05464C101 | 28,304 | 440,810 | SH | DFND | 3 | 322,011 | 0 | 118,799 | |
| Axon Enterprise Inc | COM | 05464C101 | 81,425 | 1,268,106 | SH | SOLE | 0 | 1,231,976 | 0 | 36,130 | |
| BRF SA-ADR | SPONSORED ADR | 10552T107 | 1,771 | 233,027 | SH | DFND | 1 | 233,027 | 0 | 0 | |
| BRF SA-ADR | SPONSORED ADR | 10552T107 | 13,600 | 1,789,503 | SH | DFND | 2 | 560,731 | 0 | 1,228,772 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 72,835 | 620,616 | SH | DFND | 1 | 620,616 | 0 | 0 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 1,367,881 | 11,655,432 | SH | DFND | 2 | 3,667,793 | 0 | 7,987,639 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 40,633 | 346,223 | SH | DFND | 3 | 81,821 | 0 | 264,402 | |
| Baidu.com Sponsored ADR | SPON ADR REP A | 056752108 | 263,369 | 2,244,112 | SH | SOLE | 0 | 1,677,917 | 0 | 566,195 | |
| BanColombia Pref ADR | SPON ADR PREF | 05968L102 | 43,135 | 845,117 | SH | DFND | 2 | 0 | 0 | 845,117 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 32,051 | 3,263,837 | SH | DFND | 1 | 3,263,837 | 0 | 0 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 207,366 | 21,116,735 | SH | DFND | 2 | 8,956,488 | 0 | 12,160,247 | |
| Banco Bradesco Pn ADR | SP ADR PFD NEW | 059460303 | 26,155 | 2,663,489 | SH | DFND | 3 | 2,542,139 | 0 | 121,350 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 8,171 | 112,164 | SH | DFND | 1 | 112,164 | 0 | 0 | |
| Banco Macro ADR | SPON ADR B | 05961W105 | 34,101 | 468,104 | SH | DFND | 2 | 273,011 | 0 | 195,093 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 26,511 | 531,708 | SH | DFND | 1 | 531,708 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 19,814 | 397,397 | SH | DFND | 2 | 127,851 | 0 | 269,546 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 4,881 | 97,899 | SH | DFND | 3 | 97,899 | 0 | 0 | |
| Baozun Spn Adr 1:1 | SPONSORED ADR | 06684L103 | 14,664 | 294,100 | SH | SOLE | 0 | 294,100 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 2,432 | 19,620 | SH | DFND | 1 | 19,620 | 0 | 0 | |
| Beigene Ltd | SPONSORED ADR | 07725L102 | 9,780 | 78,904 | SH | DFND | 3 | 0 | 0 | 78,904 | |
| Benefitfocus Inc | COM | 08180D106 | 8,320 | 306,448 | SH | DFND | 1 | 306,448 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 6,980 | 257,105 | SH | DFND | 2 | 65,008 | 0 | 192,097 | |
| Benefitfocus Inc | COM | 08180D106 | 1,907 | 70,226 | SH | DFND | 3 | 70,226 | 0 | 0 | |
| Benefitfocus Inc | COM | 08180D106 | 6,146 | 226,368 | SH | SOLE | 0 | 226,368 | 0 | 0 | |
| BitAuto Holdings Ltd - ADR | SPONSORED ADS | 091727107 | 571 | 54,492 | SH | SOLE | 0 | 54,492 | 0 | 0 | |
| BlackRock Floating Rate Income | COM | 091941104 | 9,963 | 802,170 | SH | DFND | 1 | 802,170 | 0 | 0 | |
| Blackline | COM | 09239B109 | 14,057 | 262,705 | SH | DFND | 1 | 262,705 | 0 | 0 | |
| Blackline | COM | 09239B109 | 10,824 | 202,284 | SH | DFND | 2 | 64,759 | 0 | 137,525 | |
| Blackline | COM | 09239B109 | 2,663 | 49,763 | SH | DFND | 3 | 49,763 | 0 | 0 | |
| Blackline | COM | 09239B109 | 7,447 | 139,175 | SH | SOLE | 0 | 139,175 | 0 | 0 | |
| Blue Apron Holdings Inc | CL A | 09523Q101 | 1,004 | 148,506 | SH | DFND | 1 | 148,506 | 0 | 0 | |
| Blue Capital Reinsurance Holdings Fund (USD) | COM | G1190F107 | 4,148 | 629,438 | SH | DFND | 1 | 629,438 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 45,450 | 357,309 | SH | DFND | 1 | 357,309 | 0 | 0 | |
| Bluebird Bio Inc | COM | 09609G100 | 272,217 | 2,140,074 | SH | DFND | 2 | 778,671 | 0 | 1,361,403 | |
| Bluebird Bio Inc | COM | 09609G100 | 14,024 | 110,254 | SH | DFND | 3 | 48,310 | 0 | 61,944 | |
| Bluebird Bio Inc | COM | 09609G100 | 205,542 | 1,615,897 | SH | SOLE | 0 | 1,233,501 | 0 | 382,396 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 3,684 | 105,637 | SH | DFND | 1 | 105,637 | 0 | 0 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 233 | 6,679 | SH | DFND | 2 | 0 | 0 | 6,679 | |
| British Amer.Tobacco - ADR | SPONSORED ADR | 110448107 | 3,400 | 97,492 | SH | SOLE | 0 | 97,492 | 0 | 0 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 34,390 | 269,349 | SH | DFND | 1 | 269,349 | 0 | 0 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 110,631 | 866,473 | SH | DFND | 2 | 625,186 | 0 | 241,287 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 24,959 | 195,479 | SH | DFND | 3 | 136,757 | 0 | 58,722 | |
| Broadridge Finl.Sltn. | COM | 11133T103 | 73,642 | 576,771 | SH | SOLE | 0 | 558,942 | 0 | 17,829 | |
| CEVA Inc | COM | 157210105 | 3,822 | 156,980 | SH | DFND | 1 | 156,980 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 3,430 | 140,869 | SH | DFND | 2 | 44,929 | 0 | 95,940 | |
| CEVA Inc | COM | 157210105 | 861 | 35,378 | SH | DFND | 3 | 35,378 | 0 | 0 | |
| CEVA Inc | COM | 157210105 | 2,009 | 82,500 | SH | SOLE | 0 | 82,500 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 22,912 | 271,635 | SH | DFND | 1 | 271,635 | 0 | 0 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 12,281 | 145,591 | SH | DFND | 2 | 130,094 | 0 | 15,497 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 1,369 | 16,226 | SH | DFND | 3 | 8,892 | 0 | 7,334 | |
| CH Robinson Worldwide | COM NEW | 12541W209 | 22,393 | 265,480 | SH | SOLE | 0 | 265,480 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 4,292 | 49,434 | SH | DFND | 1 | 49,434 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 27,344 | 314,915 | SH | DFND | 2 | 314,915 | 0 | 0 | |
| CarMax Inc | COM | 143130102 | 2,410 | 27,760 | SH | DFND | 3 | 15,188 | 0 | 12,572 | |
| CarMax Inc | COM | 143130102 | 4,383 | 50,476 | SH | SOLE | 0 | 50,476 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 27,263 | 6,429,949 | SH | DFND | 1 | 6,429,949 | 0 | 0 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 89,765 | 21,170,910 | SH | DFND | 2 | 7,078,161 | 0 | 14,092,749 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 27,888 | 6,577,347 | SH | DFND | 3 | 204,166 | 0 | 6,373,181 | |
| Cemex ADR | SPON ADR NEW | 151290889 | 5,585 | 1,317,238 | SH | SOLE | 0 | 1,317,238 | 0 | 0 | |
| Chegg | COM | 163092109 | 130,590 | 3,384,037 | SH | DFND | 1 | 3,384,037 | 0 | 0 | |
| Chegg | COM | 163092109 | 192,186 | 4,980,190 | SH | DFND | 2 | 2,158,642 | 0 | 2,821,548 | |
| Chegg | COM | 163092109 | 33,991 | 880,828 | SH | DFND | 3 | 659,817 | 0 | 221,011 | |
| Chegg | COM | 163092109 | 124,621 | 3,229,371 | SH | SOLE | 0 | 3,178,373 | 0 | 50,998 | |
| Chewy Inc | CL A | 16679L109 | 50,572 | 1,444,916 | SH | DFND | 1 | 1,444,916 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 49,259 | 1,407,395 | SH | DFND | 2 | 41,543 | 0 | 1,365,852 | |
| Chewy Inc | CL A | 16679L109 | 542 | 15,477 | SH | DFND | 3 | 15,477 | 0 | 0 | |
| Chewy Inc | CL A | 16679L109 | 16,201 | 462,898 | SH | SOLE | 0 | 462,898 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 50,405 | 68,777 | SH | DFND | 1 | 68,777 | 0 | 0 | |
| Chipotle Mexican Grill | COM | 169656105 | 166,435 | 227,097 | SH | DFND | 2 | 171,817 | 0 | 55,280 | |
| Chipotle Mexican Grill | COM | 169656105 | 37,073 | 50,585 | SH | DFND | 3 | 35,211 | 0 | 15,374 | |
| Chipotle Mexican Grill | COM | 169656105 | 105,909 | 144,511 | SH | SOLE | 0 | 139,700 | 0 | 4,811 | |
| CoStar Group | COM | 22160N109 | 86,699 | 156,480 | SH | DFND | 1 | 156,480 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 101,975 | 184,051 | SH | DFND | 2 | 28,677 | 0 | 155,374 | |
| CoStar Group | COM | 22160N109 | 940 | 1,697 | SH | DFND | 3 | 1,697 | 0 | 0 | |
| CoStar Group | COM | 22160N109 | 29,421 | 53,100 | SH | SOLE | 0 | 53,100 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 27,609 | 542,207 | SH | DFND | 1 | 542,207 | 0 | 0 | |
| Coca Cola | COM | 191216100 | 1,685 | 33,100 | SH | DFND | 2 | 0 | 0 | 33,100 | |
| Coca Cola | COM | 191216100 | 26,410 | 518,663 | SH | SOLE | 0 | 518,663 | 0 | 0 | |
| Codexis | COM | 192005106 | 20,724 | 1,124,473 | SH | DFND | 1 | 1,124,473 | 0 | 0 | |
| Codexis | COM | 192005106 | 19,512 | 1,058,708 | SH | DFND | 2 | 341,810 | 0 | 716,898 | |
| Codexis | COM | 192005106 | 4,783 | 259,514 | SH | DFND | 3 | 259,514 | 0 | 0 | |
| Codexis | COM | 192005106 | 14,009 | 760,129 | SH | SOLE | 0 | 760,129 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 14,831 | 169,148 | SH | DFND | 1 | 169,148 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 39 | 440 | SH | DFND | 2 | 440 | 0 | 0 | |
| Consolidated Edison | COM | 209115104 | 868 | 9,900 | SH | DFND | 3 | 9,900 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 11,096 | 113,728 | SH | DFND | 1 | 113,728 | 0 | 0 | |
| Copa Holdings S A | CL A | P31076105 | 216,850 | 2,222,511 | SH | DFND | 2 | 1,541,158 | 0 | 681,353 | |
| Copa Holdings S A | CL A | P31076105 | 53,091 | 544,131 | SH | DFND | 3 | 16,864 | 0 | 527,267 | |
| Copa Holdings S A | CL A | P31076105 | 27,108 | 277,829 | SH | SOLE | 0 | 277,829 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 20,768 | 90,727 | SH | DFND | 1 | 90,727 | 0 | 0 | |
| Credicorp | COM | G2519Y108 | 373,628 | 1,632,205 | SH | DFND | 2 | 801,712 | 0 | 830,493 | |
| Credicorp | COM | G2519Y108 | 48,634 | 212,461 | SH | DFND | 3 | 6,400 | 0 | 206,061 | |
| Credicorp | COM | G2519Y108 | 27,825 | 121,553 | SH | SOLE | 0 | 121,553 | 0 | 0 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 119,975 | 3,250,487 | SH | DFND | 1 | 3,250,487 | 0 | 0 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 1,157,437 | 31,358,364 | SH | DFND | 2 | 11,331,456 | 0 | 20,026,908 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 88,091 | 2,386,642 | SH | DFND | 3 | 865,221 | 0 | 1,521,421 | |
| Ctrip.com Intl Sponsored ADR | AMERICAN DEP SHS | 22943F100 | 384,921 | 10,428,650 | SH | SOLE | 0 | 8,385,532 | 0 | 2,043,118 | |
| Cullen/Frost Bankers | COM | 229899109 | 9,772 | 104,336 | SH | DFND | 1 | 104,336 | 0 | 0 | |
| Cullen/Frost Bankers | COM | 229899109 | 681 | 7,273 | SH | DFND | 2 | 0 | 0 | 7,273 | |
| Cullen/Frost Bankers | COM | 229899109 | 9,537 | 101,822 | SH | SOLE | 0 | 101,822 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 14,075 | 110,100 | SH | DFND | 1 | 110,100 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 14,305 | 111,900 | SH | DFND | 2 | 36,100 | 0 | 75,800 | |
| CyberArk Software Ltd | SHS | M2862V108 | 3,528 | 27,600 | SH | DFND | 3 | 27,600 | 0 | 0 | |
| CyberArk Software Ltd | SHS | M2862V108 | 10,291 | 80,500 | SH | SOLE | 0 | 80,500 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 38,926 | 1,875,054 | SH | DFND | 1 | 1,875,054 | 0 | 0 | |
| Denali Therapeutics | COM | 24823R105 | 38,764 | 1,867,254 | SH | DFND | 2 | 57,049 | 0 | 1,810,205 | |
| Denali Therapeutics | COM | 24823R105 | 1,584 | 76,324 | SH | DFND | 3 | 51,147 | 0 | 25,177 | |
| Denali Therapeutics | COM | 24823R105 | 74,499 | 3,588,597 | SH | SOLE | 0 | 3,588,597 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 95,885 | 639,915 | SH | DFND | 1 | 639,915 | 0 | 0 | |
| Dexcom Inc | COM | 252131107 | 447,144 | 2,984,142 | SH | DFND | 2 | 1,103,475 | 0 | 1,880,667 | |
| Dexcom Inc | COM | 252131107 | 28,706 | 191,576 | SH | DFND | 3 | 112,576 | 0 | 79,000 | |
| Dexcom Inc | COM | 252131107 | 152,785 | 1,019,656 | SH | SOLE | 0 | 533,301 | 0 | 486,355 | |
| Digimarc | COM | 25381B101 | 4,128 | 93,000 | SH | DFND | 1 | 93,000 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 12,080 | 272,144 | SH | DFND | 2 | 87,853 | 0 | 184,291 | |
| Digimarc | COM | 25381B101 | 2,950 | 66,464 | SH | DFND | 3 | 66,464 | 0 | 0 | |
| Digimarc | COM | 25381B101 | 3,618 | 81,500 | SH | SOLE | 0 | 81,500 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 7,777 | 120,385 | SH | DFND | 1 | 120,385 | 0 | 0 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 523 | 8,093 | SH | DFND | 2 | 0 | 0 | 8,093 | |
| Dolby Laboratories 'A' | COM | 25659T107 | 7,635 | 118,182 | SH | SOLE | 0 | 118,182 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 61,313 | 658,152 | SH | DFND | 1 | 658,152 | 0 | 0 | |
| EOG Resources | COM | 26875P101 | 220,563 | 2,367,574 | SH | DFND | 2 | 1,836,374 | 0 | 531,200 | |
| EOG Resources | COM | 26875P101 | 38,478 | 413,033 | SH | DFND | 3 | 268,502 | 0 | 144,531 | |
| EOG Resources | COM | 26875P101 | 127,840 | 1,372,263 | SH | SOLE | 0 | 1,329,092 | 0 | 43,171 | |
| Ecolab | COM | 278865100 | 5,295 | 26,817 | SH | DFND | 1 | 26,817 | 0 | 0 | |
| Ecolab | COM | 278865100 | 6,603 | 33,441 | SH | DFND | 2 | 20,641 | 0 | 12,800 | |
| Ecolab | COM | 278865100 | 814 | 4,124 | SH | DFND | 3 | 4,124 | 0 | 0 | |
| Edwards Lifesciences Corp | COM | 28176E108 | 245 | 1,327 | SH | DFND | 3 | 1,327 | 0 | 0 | |
| Estee Lauder 'A' | COM | 518439104 | 34,472 | 188,260 | SH | DFND | 2 | 188,260 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 21,149 | 1,305,523 | SH | DFND | 1 | 1,305,523 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 20,970 | 1,294,415 | SH | DFND | 2 | 36,931 | 0 | 1,257,484 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 232 | 14,330 | SH | DFND | 3 | 14,330 | 0 | 0 | |
| Eventbrite Inc Class A | COM CL A | 29975E109 | 5,188 | 320,263 | SH | SOLE | 0 | 320,263 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 15,336 | 202,430 | SH | DFND | 1 | 202,430 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 20 | 260 | SH | DFND | 2 | 260 | 0 | 0 | |
| Eversource Energy | COM | 30040W108 | 901 | 11,898 | SH | DFND | 3 | 11,898 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 2,860 | 359,780 | SH | DFND | 1 | 359,780 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 2,664 | 335,149 | SH | DFND | 2 | 108,242 | 0 | 226,907 | |
| Evolent Health Inc A | CL A | 30050B101 | 670 | 84,272 | SH | DFND | 3 | 84,272 | 0 | 0 | |
| Evolent Health Inc A | CL A | 30050B101 | 2,331 | 293,216 | SH | SOLE | 0 | 293,216 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 27,817 | 235,654 | SH | DFND | 1 | 235,654 | 0 | 0 | |
| Exact Sciences | COM | 30063P105 | 24,430 | 206,966 | SH | DFND | 2 | 67,778 | 0 | 139,188 | |
| Exact Sciences | COM | 30063P105 | 8,742 | 74,062 | SH | DFND | 3 | 63,949 | 0 | 10,113 | |
| Exact Sciences | COM | 30063P105 | 22,988 | 194,750 | SH | SOLE | 0 | 194,750 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 12,978 | 270,710 | SH | DFND | 1 | 270,710 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 17 | 355 | SH | DFND | 2 | 355 | 0 | 0 | |
| Exelon Corporation | COM | 30161N101 | 554 | 11,565 | SH | DFND | 3 | 11,565 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 458,799 | 2,377,199 | SH | DFND | 1 | 2,377,199 | 0 | 0 | |
| Facebook Cl.A | CL A | 30303M102 | 1,661,408 | 8,608,333 | SH | DFND | 2 | 3,614,697 | 0 | 4,993,636 | |
| Facebook Cl.A | CL A | 30303M102 | 134,778 | 698,332 | SH | DFND | 3 | 406,865 | 0 | 291,467 | |
| Facebook Cl.A | CL A | 30303M102 | 822,776 | 4,263,087 | SH | SOLE | 0 | 3,169,670 | 0 | 1,093,417 | |
| Farfetch | ORD SHS CL A | 30744W107 | 9,616 | 462,330 | SH | SOLE | 0 | 462,330 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 5,348 | 101,715 | SH | DFND | 1 | 101,715 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 7,774 | 147,854 | SH | DFND | 2 | 47,423 | 0 | 100,431 | |
| Faro Technologies | COM | 311642102 | 1,955 | 37,190 | SH | DFND | 3 | 37,190 | 0 | 0 | |
| Faro Technologies | COM | 311642102 | 5,672 | 107,880 | SH | SOLE | 0 | 107,880 | 0 | 0 | |
| Fastenal | COM | 311900104 | 25,229 | 774,123 | SH | DFND | 1 | 774,123 | 0 | 0 | |
| Fastenal | COM | 311900104 | 14,866 | 456,158 | SH | DFND | 2 | 412,861 | 0 | 43,297 | |
| Fastenal | COM | 311900104 | 2,144 | 65,800 | SH | DFND | 3 | 35,708 | 0 | 30,092 | |
| Fastenal | COM | 311900104 | 24,192 | 742,306 | SH | SOLE | 0 | 742,306 | 0 | 0 | |
| Ferrari NV | COM | N3167Y103 | 1,877,648 | 11,546,182 | SH | DFND | 2 | 3,493,842 | 0 | 8,052,340 | |
| Ferrari NV | COM | N3167Y103 | 325,729 | 2,003,000 | SH | SOLE | 0 | 2,003,000 | 0 | 0 | |
| Fiat Chrysler Automobiles | SHS | N31738102 | 515,109 | 36,876,440 | SH | DFND | 2 | 11,746,107 | 0 | 25,130,333 | |
| First Republic Bank | COM | 33616C100 | 123,286 | 1,262,525 | SH | DFND | 1 | 1,262,525 | 0 | 0 | |
| First Republic Bank | COM | 33616C100 | 154,144 | 1,578,534 | SH | DFND | 2 | 418,055 | 0 | 1,160,479 | |
| First Republic Bank | COM | 33616C100 | 5,466 | 55,971 | SH | DFND | 3 | 36,235 | 0 | 19,736 | |
| First Republic Bank | COM | 33616C100 | 46,291 | 474,048 | SH | SOLE | 0 | 474,048 | 0 | 0 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 258 | 108,200 | SH | DFND | 1 | 108,200 | 0 | 0 | |
| Foamix Pharmaceuticals | SHS | M46135105 | 265 | 111,200 | SH | SOLE | 0 | 111,200 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 59,255 | 726,882 | SH | DFND | 1 | 726,882 | 0 | 0 | |
| Fortive Corp | COM | 34959J108 | 68,760 | 843,471 | SH | DFND | 2 | 182,328 | 0 | 661,143 | |
| Fortive Corp | COM | 34959J108 | 2,586 | 31,726 | SH | DFND | 3 | 20,578 | 0 | 11,148 | |
| Fortive Corp | COM | 34959J108 | 22,101 | 271,108 | SH | SOLE | 0 | 271,108 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 89,280 | 1,184,082 | SH | DFND | 1 | 1,184,082 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 93,346 | 1,238,014 | SH | DFND | 2 | 89,770 | 0 | 1,148,244 | |
| Glaukos Corp | COM | 377322102 | 1,896 | 25,142 | SH | DFND | 3 | 25,142 | 0 | 0 | |
| Glaukos Corp | COM | 377322102 | 28,490 | 377,846 | SH | SOLE | 0 | 377,846 | 0 | 0 | |
| GrubHub Inc | COM | 400110102 | 214,433 | 2,749,499 | SH | DFND | 1 | 2,749,499 | 0 | 0 | |
| GrubHub Inc | COM | 400110102 | 324,551 | 4,161,443 | SH | DFND | 2 | 1,663,430 | 0 | 2,498,013 | |
| GrubHub Inc | COM | 400110102 | 45,896 | 588,485 | SH | DFND | 3 | 435,803 | 0 | 152,682 | |
| GrubHub Inc | COM | 400110102 | 198,202 | 2,541,380 | SH | SOLE | 0 | 2,501,903 | 0 | 39,477 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 3,599 | 101,389 | SH | DFND | 1 | 101,389 | 0 | 0 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 14,327 | 403,569 | SH | DFND | 2 | 71,617 | 0 | 331,952 | |
| Grupo Financiero Galicia ADR | COM | 399909100 | 17,696 | 498,471 | SH | DFND | 3 | 15,547 | 0 | 482,924 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 54,007 | 415,314 | SH | DFND | 2 | 308,243 | 0 | 107,071 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 18,258 | 140,404 | SH | DFND | 3 | 97,038 | 0 | 43,366 | |
| HDFC Bank ADR | ADR REPS 3 SHS | 40415F101 | 94,024 | 723,042 | SH | SOLE | 0 | 723,042 | 0 | 0 | |
| HEICO | COM | 422806109 | 20,700 | 154,699 | SH | DFND | 1 | 154,699 | 0 | 0 | |
| HEICO | COM | 422806109 | 11,760 | 87,887 | SH | SOLE | 0 | 87,887 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 39,655 | 383,618 | SH | DFND | 1 | 383,618 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 77,835 | 752,974 | SH | DFND | 2 | 225,473 | 0 | 527,501 | |
| HEICO 'A' | CL A | 422806208 | 578 | 5,593 | SH | DFND | 3 | 5,593 | 0 | 0 | |
| HEICO 'A' | CL A | 422806208 | 7,845 | 75,893 | SH | SOLE | 0 | 75,893 | 0 | 0 | |
| Himax Technologies Adr | SPONSORED ADR | 43289P106 | 2,352 | 675,800 | SH | DFND | 3 | 0 | 0 | 675,800 | |
| Howard Hughes | COM | 44267D107 | 30,294 | 244,623 | SH | DFND | 1 | 244,623 | 0 | 0 | |
| Howard Hughes | COM | 44267D107 | 94,465 | 762,802 | SH | DFND | 2 | 569,300 | 0 | 193,502 | |
| Howard Hughes | COM | 44267D107 | 21,751 | 175,634 | SH | DFND | 3 | 123,021 | 0 | 52,613 | |
| Howard Hughes | COM | 44267D107 | 65,346 | 527,668 | SH | SOLE | 0 | 511,040 | 0 | 16,628 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 589 | 26,765 | SH | DFND | 1 | 26,765 | 0 | 0 | |
| Hutchison China Meditech | SPONSORED ADR | 44842L103 | 4,205 | 191,146 | SH | DFND | 3 | 0 | 0 | 191,146 | |
| ICICI Bank ADR | ADR | 45104G104 | 133,634 | 10,614,258 | SH | DFND | 1 | 10,614,258 | 0 | 0 | |
| ICICI Bank ADR | ADR | 45104G104 | 146,905 | 11,668,371 | SH | DFND | 2 | 8,209,669 | 0 | 3,458,702 | |
| ICICI Bank ADR | ADR | 45104G104 | 67,632 | 5,371,903 | SH | DFND | 3 | 3,988,010 | 0 | 1,383,893 | |
| ICICI Bank ADR | ADR | 45104G104 | 198,432 | 15,761,105 | SH | SOLE | 0 | 15,761,105 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 12,332 | 79,947 | SH | DFND | 1 | 79,947 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 15,057 | 97,617 | SH | DFND | 2 | 31,506 | 0 | 66,111 | |
| IPG Photonics Corp | COM | 44980X109 | 3,677 | 23,841 | SH | DFND | 3 | 23,841 | 0 | 0 | |
| IPG Photonics Corp | COM | 44980X109 | 11,358 | 73,636 | SH | SOLE | 0 | 73,636 | 0 | 0 | |
| Illumina | COM | 452327109 | 592,509 | 1,609,422 | SH | DFND | 1 | 1,609,422 | 0 | 0 | |
| Illumina | COM | 452327109 | 3,658,908 | 9,938,633 | SH | DFND | 2 | 2,698,681 | 0 | 7,239,952 | |
| Illumina | COM | 452327109 | 137,146 | 372,528 | SH | DFND | 3 | 189,938 | 0 | 182,590 | |
| Illumina | COM | 452327109 | 1,787,218 | 4,854,592 | SH | SOLE | 0 | 3,895,156 | 0 | 959,436 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 8,568 | 800,786 | SH | DFND | 1 | 800,786 | 0 | 0 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 2,778 | 259,586 | SH | DFND | 2 | 236,023 | 0 | 23,563 | |
| Infosys Ltd ADR | SPONSORED ADR | 456788108 | 2,615 | 244,360 | SH | DFND | 3 | 121,943 | 0 | 122,417 | |
| Interactive Brokers Group | COM | 45841N107 | 95,392 | 1,749,984 | SH | DFND | 1 | 1,749,984 | 0 | 0 | |
| Interactive Brokers Group | COM | 45841N107 | 184,880 | 3,391,663 | SH | DFND | 2 | 1,921,895 | 0 | 1,469,768 | |
| Interactive Brokers Group | COM | 45841N107 | 28,222 | 517,745 | SH | DFND | 3 | 356,818 | 0 | 160,927 | |
| Interactive Brokers Group | COM | 45841N107 | 95,095 | 1,744,542 | SH | SOLE | 0 | 1,703,956 | 0 | 40,586 | |
| Intuitive Surgical | COM NEW | 46120E602 | 106,148 | 202,361 | SH | DFND | 1 | 202,361 | 0 | 0 | |
| Intuitive Surgical | COM NEW | 46120E602 | 624,611 | 1,190,756 | SH | DFND | 2 | 433,615 | 0 | 757,141 | |
| Intuitive Surgical | COM NEW | 46120E602 | 32,395 | 61,758 | SH | DFND | 3 | 27,375 | 0 | 34,383 | |
| Intuitive Surgical | COM NEW | 46120E602 | 345,225 | 658,136 | SH | SOLE | 0 | 445,385 | 0 | 212,751 | |
| Invesco Senior Income Trust | COM | 46131H107 | 12,952 | 2,998,119 | SH | DFND | 1 | 2,998,119 | 0 | 0 | |
| Invesco Senior Income Trust | COM | 46131H107 | 1,350 | 312,581 | SH | DFND | 3 | 312,581 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 58,932 | 916,946 | SH | DFND | 1 | 916,946 | 0 | 0 | |
| Ionis Pharmaceuticals | COM | 462222100 | 345,558 | 5,376,663 | SH | DFND | 2 | 1,964,325 | 0 | 3,412,338 | |
| Ionis Pharmaceuticals | COM | 462222100 | 17,995 | 279,989 | SH | DFND | 3 | 123,983 | 0 | 156,006 | |
| Ionis Pharmaceuticals | COM | 462222100 | 120,227 | 1,870,651 | SH | SOLE | 0 | 910,244 | 0 | 960,407 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 19,370 | 2,056,302 | SH | DFND | 1 | 2,056,302 | 0 | 0 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 276,216 | 29,322,315 | SH | DFND | 2 | 12,743,155 | 0 | 16,579,160 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 92,467 | 9,816,063 | SH | DFND | 3 | 309,677 | 0 | 9,506,386 | |
| Itau Unibanco Holding SA-ADR | SPON ADR REP PFD | 465562106 | 19,768 | 2,098,498 | SH | SOLE | 0 | 2,098,498 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 31,396 | 1,036,502 | SH | DFND | 1 | 1,036,502 | 0 | 0 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 160,115 | 5,286,083 | SH | DFND | 2 | 3,468,827 | 0 | 1,817,256 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 53,617 | 1,770,131 | SH | DFND | 3 | 89,690 | 0 | 1,680,441 | |
| JD.Com Inc - ADR | SPON ADR CL A | 47215P106 | 10,068 | 332,377 | SH | SOLE | 0 | 332,377 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 38,436 | 1,998,775 | SH | DFND | 1 | 1,998,775 | 0 | 0 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 119,345 | 6,206,213 | SH | DFND | 2 | 4,678,405 | 0 | 1,527,808 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 27,480 | 1,429,023 | SH | DFND | 3 | 1,001,759 | 0 | 427,264 | |
| Jefferies Financial Group Inc | COM | 47233W109 | 80,421 | 4,182,051 | SH | SOLE | 0 | 4,052,309 | 0 | 129,742 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 8,707 | 2,328,170 | SH | DFND | 1 | 2,328,170 | 0 | 0 | |
| Jianpu Technology Inc- ADR | ADR | 47738D101 | 5,550 | 1,484,017 | SH | SOLE | 0 | 1,484,017 | 0 | 0 | |
| Johnson & Johnson | COM | 478160104 | 7,200 | 51,692 | SH | DFND | 1 | 51,692 | 0 | 0 | |
| Johnson & Johnson | COM | 478160104 | 497 | 3,570 | SH | DFND | 2 | 0 | 0 | 3,570 | |
| Johnson & Johnson | COM | 478160104 | 7,037 | 50,522 | SH | SOLE | 0 | 50,522 | 0 | 0 | |
| Jumia Technologies Ag ADR | SPONSORED ADS | 48138M105 | 237,842 | 9,002,358 | SH | DFND | 2 | 1,611,645 | 0 | 7,390,713 | |
| Kaleido Biosciences Inc | COM | 483347100 | 2,859 | 246,500 | SH | DFND | 1 | 246,500 | 0 | 0 | |
| Kaleido Biosciences Inc | COM | 483347100 | 2,245 | 193,500 | SH | SOLE | 0 | 193,500 | 0 | 0 | |
| Kirby | COM | 497266106 | 86,441 | 1,094,186 | SH | DFND | 1 | 1,094,186 | 0 | 0 | |
| Kirby | COM | 497266106 | 275,418 | 3,486,304 | SH | DFND | 2 | 2,638,492 | 0 | 847,812 | |
| Kirby | COM | 497266106 | 62,712 | 793,824 | SH | DFND | 3 | 554,855 | 0 | 238,969 | |
| Kirby | COM | 497266106 | 182,090 | 2,304,931 | SH | SOLE | 0 | 2,231,307 | 0 | 73,624 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 19 | 1,700 | SH | DFND | 2 | 1,700 | 0 | 0 | |
| Korea Electric Power ADR | SPONSORED ADR | 500631106 | 1,050 | 94,600 | SH | DFND | 3 | 94,600 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 109,942 | 261,747 | SH | DFND | 1 | 261,747 | 0 | 0 | |
| LendingTree | COM | 52603B107 | 242,002 | 576,153 | SH | DFND | 2 | 353,603 | 0 | 222,550 | |
| LendingTree | COM | 52603B107 | 60,268 | 143,484 | SH | DFND | 3 | 111,668 | 0 | 31,816 | |
| LendingTree | COM | 52603B107 | 163,908 | 390,230 | SH | SOLE | 0 | 382,221 | 0 | 8,009 | |
| Liberty Media Corp | DEB 4.00011/1 | 530715AG6 | 15,010 | 21,176,000 | SH | DFND | 1 | 21,176,000 | 0 | 0 | |
| Liberty Media Corp | DEB 4.00011/1 | 530715AG6 | 6 | 9,000 | SH | DFND | 2 | 9,000 | 0 | 0 | |
| Liberty Media Corp | DEB 4.00011/1 | 530715AG6 | 1,211 | 1,708,000 | SH | DFND | 3 | 1,708,000 | 0 | 0 | |
| Lindblad Expeditions Holdings | COM | 535219109 | 19,255 | 1,072,701 | SH | SOLE | 0 | 1,072,701 | 0 | 0 | |
| Line Corp Sponsored Adr | SPONSORED ADR | 53567X101 | 8,700 | 309,160 | SH | DFND | 2 | 12,284 | 0 | 296,876 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 41,392 | 629,920 | SH | DFND | 1 | 629,920 | 0 | 0 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 40,593 | 617,760 | SH | DFND | 2 | 19,553 | 0 | 598,207 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 1,568 | 23,855 | SH | DFND | 3 | 15,929 | 0 | 7,926 | |
| Lyft Inc Class A Common | CL A COM | 55087P104 | 30,468 | 463,672 | SH | SOLE | 0 | 463,672 | 0 | 0 | |
| M&T Bank | COM | 55261F104 | 16,457 | 96,766 | SH | DFND | 2 | 96,766 | 0 | 0 | |
| MRC Global | COM | 55345K103 | 11,128 | 650,000 | SH | SOLE | 0 | 650,000 | 0 | 0 | |
| MakeMyTrip | SHS | V5633W109 | 80,095 | 3,229,648 | SH | DFND | 2 | 2,051,378 | 0 | 1,178,270 | |
| Markel Corp | COM | 570535104 | 111,158 | 102,017 | SH | DFND | 1 | 102,017 | 0 | 0 | |
| Markel Corp | COM | 570535104 | 289,300 | 265,510 | SH | DFND | 2 | 181,041 | 0 | 84,469 | |
| Markel Corp | COM | 570535104 | 53,529 | 49,127 | SH | DFND | 3 | 34,137 | 0 | 14,990 | |
| Markel Corp | COM | 570535104 | 167,107 | 153,365 | SH | SOLE | 0 | 149,243 | 0 | 4,122 | |
| MarketAxess Holdings | COM | 57060D108 | 384,772 | 1,197,099 | SH | DFND | 1 | 1,197,099 | 0 | 0 | |
| MarketAxess Holdings | COM | 57060D108 | 620,151 | 1,929,410 | SH | DFND | 2 | 874,509 | 0 | 1,054,901 | |
| MarketAxess Holdings | COM | 57060D108 | 86,342 | 268,628 | SH | DFND | 3 | 196,988 | 0 | 71,640 | |
| MarketAxess Holdings | COM | 57060D108 | 315,239 | 980,769 | SH | SOLE | 0 | 962,692 | 0 | 18,077 | |
| Martin Marietta Materials | COM | 573284106 | 92,320 | 401,198 | SH | DFND | 1 | 401,198 | 0 | 0 | |
| Martin Marietta Materials | COM | 573284106 | 305,183 | 1,326,250 | SH | DFND | 2 | 1,016,926 | 0 | 309,324 | |
| Martin Marietta Materials | COM | 573284106 | 66,759 | 290,116 | SH | DFND | 3 | 203,796 | 0 | 86,320 | |
| Martin Marietta Materials | COM | 573284106 | 197,586 | 858,661 | SH | SOLE | 0 | 831,498 | 0 | 27,163 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 331,887 | 1,254,630 | SH | DFND | 1 | 1,254,630 | 0 | 0 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 757,857 | 2,864,918 | SH | DFND | 2 | 1,772,069 | 0 | 1,092,849 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 125,904 | 475,955 | SH | DFND | 3 | 332,943 | 0 | 143,012 | |
| MasterCard Inc-Class A | CL A | 57636Q104 | 408,720 | 1,545,080 | SH | SOLE | 0 | 1,501,982 | 0 | 43,098 | |
| McDonald's | COM | 580135101 | 19,204 | 92,476 | SH | DFND | 1 | 92,476 | 0 | 0 | |
| McDonald's | COM | 580135101 | 1,268 | 6,104 | SH | DFND | 2 | 0 | 0 | 6,104 | |
| McDonald's | COM | 580135101 | 19,171 | 92,321 | SH | SOLE | 0 | 92,321 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 101,051 | 165,178 | SH | DFND | 1 | 165,178 | 0 | 0 | |
| MercadoLibre | COM | 58733R102 | 2,475,790 | 4,046,929 | SH | DFND | 2 | 1,426,898 | 0 | 2,620,031 | |
| MercadoLibre | COM | 58733R102 | 152,254 | 248,874 | SH | DFND | 3 | 16,074 | 0 | 232,800 | |
| MercadoLibre | COM | 58733R102 | 123,842 | 202,433 | SH | SOLE | 0 | 202,433 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 83,154 | 98,993 | SH | DFND | 1 | 98,993 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 403,525 | 480,387 | SH | DFND | 2 | 317,024 | 0 | 163,363 | |
| Mettler-Toledo | COM | 592688105 | 3,172 | 3,776 | SH | DFND | 3 | 3,776 | 0 | 0 | |
| Mettler-Toledo | COM | 592688105 | 40,427 | 48,127 | SH | SOLE | 0 | 48,127 | 0 | 0 | |
| Microsoft | COM | 594918104 | 119,125 | 889,260 | SH | DFND | 1 | 889,260 | 0 | 0 | |
| Microsoft | COM | 594918104 | 363,101 | 2,710,520 | SH | DFND | 2 | 2,131,285 | 0 | 579,235 | |
| Microsoft | COM | 594918104 | 70,093 | 523,238 | SH | DFND | 3 | 366,617 | 0 | 156,621 | |
| Microsoft | COM | 594918104 | 224,090 | 1,672,810 | SH | SOLE | 0 | 1,625,830 | 0 | 46,980 | |
| Mobile Telesystems ADR | SPONSORED ADR | 607409109 | 196 | 21,100 | SH | DFND | 1 | 21,100 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 19,868 | 1,357,080 | SH | DFND | 1 | 1,357,080 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 20,491 | 1,399,664 | SH | DFND | 2 | 116,368 | 0 | 1,283,296 | |
| Moderna Inc | COM | 60770K107 | 508 | 34,699 | SH | DFND | 3 | 34,699 | 0 | 0 | |
| Moderna Inc | COM | 60770K107 | 6,092 | 416,152 | SH | SOLE | 0 | 416,152 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 162,615 | 832,597 | SH | DFND | 1 | 832,597 | 0 | 0 | |
| Moody's Corp | COM | 615369105 | 542,990 | 2,780,146 | SH | DFND | 2 | 2,112,436 | 0 | 667,710 | |
| Moody's Corp | COM | 615369105 | 119,017 | 609,374 | SH | DFND | 3 | 427,039 | 0 | 182,335 | |
| Moody's Corp | COM | 615369105 | 341,736 | 1,749,713 | SH | SOLE | 0 | 1,694,316 | 0 | 55,397 | |
| Myriad Genetics Inc | COM | 62855J104 | 38,710 | 1,393,446 | SH | DFND | 1 | 1,393,446 | 0 | 0 | |
| Myriad Genetics Inc | COM | 62855J104 | 119,760 | 4,311,000 | SH | DFND | 2 | 3,247,326 | 0 | 1,063,674 | |
| Myriad Genetics Inc | COM | 62855J104 | 27,347 | 984,405 | SH | DFND | 3 | 683,602 | 0 | 300,803 | |
| Myriad Genetics Inc | COM | 62855J104 | 78,848 | 2,838,291 | SH | SOLE | 0 | 2,746,649 | 0 | 91,642 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 12,817 | 5,026,397 | SH | DFND | 1 | 5,026,397 | 0 | 0 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 154,475 | 60,578,372 | SH | DFND | 2 | 18,470,282 | 0 | 42,108,090 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 3,876 | 1,519,827 | SH | DFND | 3 | 661,744 | 0 | 858,083 | |
| NIO Inc ADR | SPON ADS | 62914V106 | 84,677 | 33,206,612 | SH | SOLE | 0 | 27,987,470 | 0 | 5,219,142 | |
| NVIDIA | COM | 67066G104 | 141,415 | 861,076 | SH | DFND | 1 | 861,076 | 0 | 0 | |
| NVIDIA | COM | 67066G104 | 692,571 | 4,217,077 | SH | DFND | 2 | 1,578,097 | 0 | 2,638,980 | |
| NVIDIA | COM | 67066G104 | 33,698 | 205,187 | SH | DFND | 3 | 93,590 | 0 | 111,597 | |
| NVIDIA | COM | 67066G104 | 373,426 | 2,273,798 | SH | SOLE | 0 | 1,591,029 | 0 | 682,769 | |
| National Instruments Corp | COM | 636518102 | 13,606 | 324,034 | SH | DFND | 1 | 324,034 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 6,327 | 150,675 | SH | DFND | 2 | 43,711 | 0 | 106,964 | |
| National Instruments Corp | COM | 636518102 | 1,396 | 33,249 | SH | DFND | 3 | 33,249 | 0 | 0 | |
| National Instruments Corp | COM | 636518102 | 13,870 | 330,310 | SH | SOLE | 0 | 330,310 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 61,373 | 239,952 | SH | DFND | 1 | 239,952 | 0 | 0 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 333,411 | 1,303,559 | SH | DFND | 2 | 467,425 | 0 | 836,134 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 17,553 | 68,627 | SH | DFND | 3 | 29,906 | 0 | 38,721 | |
| NetEase.com ADR | SPONSORED ADR | 64110W102 | 117,959 | 461,193 | SH | SOLE | 0 | 225,965 | 0 | 235,228 | |
| Netflix Inc | COM | 64110L106 | 447,610 | 1,218,583 | SH | DFND | 1 | 1,218,583 | 0 | 0 | |
| Netflix Inc | COM | 64110L106 | 1,426,028 | 3,882,249 | SH | DFND | 2 | 1,471,921 | 0 | 2,410,328 | |
| Netflix Inc | COM | 64110L106 | 95,371 | 259,639 | SH | DFND | 3 | 144,538 | 0 | 115,101 | |
| Netflix Inc | COM | 64110L106 | 875,334 | 2,383,028 | SH | SOLE | 0 | 1,888,269 | 0 | 494,759 | |
| New Relic | COM | 64829B100 | 46,347 | 535,745 | SH | DFND | 1 | 535,745 | 0 | 0 | |
| New Relic | COM | 64829B100 | 46,838 | 541,421 | SH | DFND | 2 | 15,992 | 0 | 525,429 | |
| New Relic | COM | 64829B100 | 488 | 5,642 | SH | DFND | 3 | 5,642 | 0 | 0 | |
| New Relic | COM | 64829B100 | 15,314 | 177,015 | SH | SOLE | 0 | 177,015 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 165,973 | 2,624,908 | SH | DFND | 1 | 2,624,908 | 0 | 0 | |
| Novocure Ltd | ORD SHS | G6674U108 | 233,033 | 3,685,474 | SH | DFND | 2 | 1,352,669 | 0 | 2,332,805 | |
| Novocure Ltd | ORD SHS | G6674U108 | 30,702 | 485,559 | SH | DFND | 3 | 379,739 | 0 | 105,820 | |
| Novocure Ltd | ORD SHS | G6674U108 | 128,579 | 2,033,508 | SH | SOLE | 0 | 2,001,949 | 0 | 31,559 | |
| Now Inc/DE | COM | 67011P100 | 54,326 | 3,680,611 | SH | DFND | 1 | 3,680,611 | 0 | 0 | |
| Now Inc/DE | COM | 67011P100 | 109,529 | 7,420,684 | SH | DFND | 2 | 4,045,221 | 0 | 3,375,463 | |
| Now Inc/DE | COM | 67011P100 | 15,135 | 1,025,405 | SH | DFND | 3 | 733,891 | 0 | 291,514 | |
| Now Inc/DE | COM | 67011P100 | 64,798 | 4,390,100 | SH | SOLE | 0 | 4,292,604 | 0 | 97,496 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 5,099 | 491,208 | SH | DFND | 1 | 491,208 | 0 | 0 | |
| Nucana Plc ADR | SPONSORED ADR | 67022C106 | 3,489 | 336,100 | SH | SOLE | 0 | 336,100 | 0 | 0 | |
| Nuveen Senior Income Fund | COM | 67067Y104 | 2,275 | 383,602 | SH | DFND | 1 | 383,602 | 0 | 0 | |
| Orchard Therapeutics PLC ADR | ADS | 68570P101 | 12,941 | 925,000 | SH | SOLE | 0 | 925,000 | 0 | 0 | |
| Pacira BioSciences | COM | 695127100 | 15,209 | 349,722 | SH | DFND | 1 | 349,722 | 0 | 0 | |
| Pacira BioSciences | COM | 695127100 | 13,007 | 299,076 | SH | DFND | 2 | 97,802 | 0 | 201,274 | |
| Pacira BioSciences | COM | 695127100 | 4,182 | 96,163 | SH | DFND | 3 | 85,438 | 0 | 10,725 | |
| Pacira BioSciences | COM | 695127100 | 10,867 | 249,878 | SH | SOLE | 0 | 249,878 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 72,487 | 453,046 | SH | DFND | 1 | 453,046 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 72,300 | 451,873 | SH | DFND | 2 | 30,157 | 0 | 421,716 | |
| Penumbra Inc | COM | 70975L107 | 3,137 | 19,606 | SH | DFND | 3 | 19,606 | 0 | 0 | |
| Penumbra Inc | COM | 70975L107 | 27,405 | 171,280 | SH | SOLE | 0 | 171,280 | 0 | 0 | |
| Pepsico | COM | 713448108 | 22,343 | 170,390 | SH | DFND | 1 | 170,390 | 0 | 0 | |
| Pepsico | COM | 713448108 | 1,418 | 10,814 | SH | DFND | 2 | 0 | 0 | 10,814 | |
| Pepsico | COM | 713448108 | 21,814 | 166,354 | SH | SOLE | 0 | 166,354 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 62,055 | 3,985,555 | SH | DFND | 1 | 3,985,555 | 0 | 0 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 377,697 | 24,258,011 | SH | DFND | 2 | 6,067,058 | 0 | 18,190,953 | |
| Petrobras Common ADR | SPONSORED ADR | 71654V408 | 12,837 | 824,446 | SH | SOLE | 0 | 824,446 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 8,208 | 578,060 | SH | DFND | 1 | 578,060 | 0 | 0 | |
| Petrobras Pref ADR | SP ADR NON VTG | 71654V101 | 61,295 | 4,316,539 | SH | DFND | 2 | 1,407,207 | 0 | 2,909,332 | |
| Pinduoduo Inc ADR | SPONSORED ADS | 722304102 | 43,062 | 2,087,330 | SH | SOLE | 0 | 2,087,330 | 0 | 0 | |
| Pioneer Floating Rate Trust | COM | 72369J102 | 5,890 | 550,936 | SH | DFND | 1 | 550,936 | 0 | 0 | |
| PriceSmart | COM | 741511109 | 16,613 | 324,979 | SH | DFND | 2 | 254,019 | 0 | 70,960 | |
| PriceSmart | COM | 741511109 | 2,484 | 48,599 | SH | SOLE | 0 | 48,599 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 25,063 | 228,571 | SH | DFND | 1 | 228,571 | 0 | 0 | |
| Procter & Gamble | COM | 742718109 | 1,589 | 14,495 | SH | DFND | 2 | 0 | 0 | 14,495 | |
| Procter & Gamble | COM | 742718109 | 24,577 | 224,145 | SH | SOLE | 0 | 224,145 | 0 | 0 | |
| Redfin | COM | 75737F108 | 43,773 | 2,434,556 | SH | DFND | 1 | 2,434,556 | 0 | 0 | |
| Redfin | COM | 75737F108 | 41,608 | 2,314,117 | SH | DFND | 2 | 75,406 | 0 | 2,238,711 | |
| Redfin | COM | 75737F108 | 1,921 | 106,866 | SH | DFND | 3 | 69,645 | 0 | 37,221 | |
| Redfin | COM | 75737F108 | 16,613 | 923,977 | SH | SOLE | 0 | 923,977 | 0 | 0 | |
| ResMed | COM | 761152107 | 83,322 | 682,796 | SH | DFND | 1 | 682,796 | 0 | 0 | |
| ResMed | COM | 761152107 | 266,633 | 2,184,978 | SH | DFND | 2 | 1,656,963 | 0 | 528,015 | |
| ResMed | COM | 761152107 | 61,060 | 500,366 | SH | DFND | 3 | 350,419 | 0 | 149,947 | |
| ResMed | COM | 761152107 | 177,699 | 1,456,194 | SH | SOLE | 0 | 1,411,240 | 0 | 44,954 | |
| ResTORbio Inc | COM | 76133L103 | 6,672 | 654,147 | SH | DFND | 1 | 654,147 | 0 | 0 | |
| ResTORbio Inc | COM | 76133L103 | 6,296 | 617,240 | SH | SOLE | 0 | 617,240 | 0 | 0 | |
| Rio Tinto Spn.Adr 1:1 | SPONSORED ADR | 767204100 | 4,403 | 70,626 | SH | DFND | 2 | 70,626 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 34,262 | 1,031,366 | SH | DFND | 1 | 1,031,366 | 0 | 0 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 171,869 | 5,173,665 | SH | DFND | 2 | 3,930,397 | 0 | 1,243,268 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 24,114 | 725,888 | SH | DFND | 3 | 505,461 | 0 | 220,427 | |
| Ritchie Bros Auctioneers (USA) | COM | 767744105 | 70,091 | 2,109,903 | SH | SOLE | 0 | 2,042,011 | 0 | 67,892 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 50,029 | 1,501,164 | SH | DFND | 2 | 766,402 | 0 | 734,762 | |
| Ritchie Bros. Auctioneers | COM | 767744105 | 14,462 | 433,928 | SH | SOLE | 0 | 433,928 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 86,136 | 950,934 | SH | DFND | 1 | 950,934 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 90,177 | 995,550 | SH | DFND | 2 | 28,758 | 0 | 966,792 | |
| Roku | COM CL A | 77543R102 | 911 | 10,057 | SH | DFND | 3 | 10,057 | 0 | 0 | |
| Roku | COM CL A | 77543R102 | 29,024 | 320,422 | SH | SOLE | 0 | 320,422 | 0 | 0 | |
| Royal Crbn.Cruises | COM | V7780T103 | 79,544 | 656,249 | SH | DFND | 1 | 656,249 | 0 | 0 | |
| Royal Crbn.Cruises | COM | V7780T103 | 256,964 | 2,119,989 | SH | DFND | 2 | 1,597,666 | 0 | 522,323 | |
| Royal Crbn.Cruises | COM | V7780T103 | 58,069 | 479,076 | SH | DFND | 3 | 336,408 | 0 | 142,668 | |
| Royal Crbn.Cruises | COM | V7780T103 | 167,389 | 1,380,987 | SH | SOLE | 0 | 1,338,625 | 0 | 42,362 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 7,091 | 450,800 | SH | DFND | 1 | 450,800 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 2,497 | 158,748 | SH | DFND | 2 | 51,470 | 0 | 107,278 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 717 | 45,569 | SH | DFND | 3 | 45,569 | 0 | 0 | |
| Rubius Therapeutics Inc | COM | 78116T103 | 56,307 | 3,579,565 | SH | SOLE | 0 | 3,579,565 | 0 | 0 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 453,981 | 7,077,969 | SH | DFND | 2 | 4,951,219 | 0 | 2,126,750 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 4,341 | 67,686 | SH | DFND | 3 | 8,377 | 0 | 59,309 | |
| Ryanair ADR | SPONSORED ADR NE | 783513203 | 3,393 | 52,904 | SH | SOLE | 0 | 52,904 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 17,862 | 537,684 | SH | DFND | 1 | 537,684 | 0 | 0 | |
| SEA Ltd ADR | ADR | 81141R100 | 74,730 | 2,249,558 | SH | DFND | 2 | 0 | 0 | 2,249,558 | |
| SEA Ltd ADR | ADR | 81141R100 | 21,297 | 641,104 | SH | SOLE | 0 | 641,104 | 0 | 0 | |
| SINA Corp | ORD | G81477104 | 5,674 | 131,550 | SH | DFND | 3 | 0 | 0 | 131,550 | |
| Salesforce.com | COM | 79466L302 | 84,887 | 559,460 | SH | DFND | 1 | 559,460 | 0 | 0 | |
| Salesforce.com | COM | 79466L302 | 502,646 | 3,312,763 | SH | DFND | 2 | 1,204,562 | 0 | 2,108,201 | |
| Salesforce.com | COM | 79466L302 | 25,940 | 170,963 | SH | DFND | 3 | 75,524 | 0 | 95,439 | |
| Salesforce.com | COM | 79466L302 | 173,813 | 1,145,542 | SH | SOLE | 0 | 556,366 | 0 | 589,176 | |
| Schlumberger | COM | 806857108 | 4,392 | 110,529 | SH | DFND | 2 | 110,529 | 0 | 0 | |
| Seattle Genetics | COM | 812578102 | 68,822 | 994,394 | SH | DFND | 1 | 994,394 | 0 | 0 | |
| Seattle Genetics | COM | 812578102 | 206,273 | 2,980,393 | SH | DFND | 2 | 2,219,714 | 0 | 760,679 | |
| Seattle Genetics | COM | 812578102 | 46,330 | 669,406 | SH | DFND | 3 | 472,891 | 0 | 196,515 | |
| Seattle Genetics | COM | 812578102 | 140,882 | 2,035,573 | SH | SOLE | 0 | 1,978,327 | 0 | 57,246 | |
| Service Corp.Intl. | COM | 817565104 | 78,029 | 1,668,008 | SH | DFND | 1 | 1,668,008 | 0 | 0 | |
| Service Corp.Intl. | COM | 817565104 | 252,252 | 5,392,310 | SH | DFND | 2 | 4,078,964 | 0 | 1,313,346 | |
| Service Corp.Intl. | COM | 817565104 | 57,442 | 1,227,912 | SH | DFND | 3 | 855,692 | 0 | 372,220 | |
| Service Corp.Intl. | COM | 817565104 | 166,094 | 3,550,524 | SH | SOLE | 0 | 3,443,048 | 0 | 107,476 | |
| Severstal GDR Reg S | COM | 818150302 | 173 | 10,286 | SH | DFND | 1 | 10,286 | 0 | 0 | |
| Sherwin-Williams Co | COM | 824348106 | 8,975 | 19,584 | SH | DFND | 2 | 19,584 | 0 | 0 | |
| Shopify 'A' | CL A | 82509L107 | 362,510 | 1,207,762 | SH | DFND | 1 | 1,207,762 | 0 | 0 | |
| Shopify 'A' | CL A | 82509L107 | 1,056,712 | 3,520,612 | SH | DFND | 2 | 1,658,969 | 0 | 1,861,643 | |
| Shopify 'A' | CL A | 82509L107 | 76,201 | 253,876 | SH | DFND | 3 | 159,920 | 0 | 93,956 | |
| Shopify 'A' | CL A | 82509L107 | 431,214 | 1,436,663 | SH | SOLE | 0 | 1,201,534 | 0 | 235,129 | |
| SiteOne Landscape Supply | COM | 82982L103 | 39,246 | 566,327 | SH | DFND | 1 | 566,327 | 0 | 0 | |
| SiteOne Landscape Supply | COM | 82982L103 | 126,658 | 1,827,683 | SH | DFND | 2 | 1,376,750 | 0 | 450,933 | |
| SiteOne Landscape Supply | COM | 82982L103 | 28,515 | 411,478 | SH | DFND | 3 | 288,053 | 0 | 123,425 | |
| SiteOne Landscape Supply | COM | 82982L103 | 83,987 | 1,211,936 | SH | SOLE | 0 | 1,174,489 | 0 | 37,447 | |
| Snap Inc | CL A | 83304A106 | 2,648 | 185,160 | SH | DFND | 2 | 185,160 | 0 | 0 | |
| Sohu.com | COM | 83410S108 | 2,802 | 200,140 | SH | DFND | 3 | 0 | 0 | 200,140 | |
| Solarcity Corp | NOTE 1.625 11/0 | 83416TAC4 | 31,775 | 32,760,000 | SH | DFND | 1 | 32,760,000 | 0 | 0 | |
| Solarcity Corp | NOTE 1.625 11/0 | 83416TAC4 | 7 | 7,000 | SH | DFND | 2 | 7,000 | 0 | 0 | |
| Solarcity Corp | NOTE 1.625 11/0 | 83416TAC4 | 5,586 | 5,759,000 | SH | DFND | 3 | 5,759,000 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 12,693 | 100,940 | SH | DFND | 1 | 100,940 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 15,935 | 126,723 | SH | DFND | 2 | 41,028 | 0 | 85,695 | |
| Splunk Inc | COM | 848637104 | 3,938 | 31,317 | SH | DFND | 3 | 31,317 | 0 | 0 | |
| Splunk Inc | COM | 848637104 | 9,291 | 73,884 | SH | SOLE | 0 | 73,884 | 0 | 0 | |
| Spotify Technology SA | SHS | L8681T102 | 175,690 | 1,201,548 | SH | DFND | 1 | 1,201,548 | 0 | 0 | |
| Spotify Technology SA | SHS | L8681T102 | 2,012,388 | 13,762,742 | SH | DFND | 2 | 5,462,824 | 0 | 8,299,918 | |
| Spotify Technology SA | SHS | L8681T102 | 53,552 | 366,245 | SH | DFND | 3 | 210,869 | 0 | 155,376 | |
| Spotify Technology SA | SHS | L8681T102 | 550,488 | 3,764,791 | SH | SOLE | 0 | 3,095,405 | 0 | 669,386 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 20,420 | 695,023 | SH | DFND | 1 | 695,023 | 0 | 0 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 14,178 | 482,565 | SH | DFND | 2 | 159,991 | 0 | 322,574 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 4,719 | 160,604 | SH | DFND | 3 | 140,678 | 0 | 19,926 | |
| Staar Surgical | COM PAR $0.01 | 852312305 | 12,910 | 439,430 | SH | SOLE | 0 | 439,430 | 0 | 0 | |
| Stericycle Inc | COM | 858912108 | 36,311 | 760,447 | SH | DFND | 1 | 760,447 | 0 | 0 | |
| Stericycle Inc | COM | 858912108 | 115,796 | 2,425,052 | SH | DFND | 2 | 1,833,661 | 0 | 591,391 | |
| Stericycle Inc | COM | 858912108 | 26,473 | 554,401 | SH | DFND | 3 | 385,632 | 0 | 168,769 | |
| Stericycle Inc | COM | 858912108 | 78,060 | 1,634,756 | SH | SOLE | 0 | 1,583,992 | 0 | 50,764 | |
| Stitch Fix | COM CL A | 860897107 | 60,307 | 1,885,169 | SH | DFND | 1 | 1,885,169 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 61,990 | 1,937,787 | SH | DFND | 2 | 57,028 | 0 | 1,880,759 | |
| Stitch Fix | COM CL A | 860897107 | 659 | 20,601 | SH | DFND | 3 | 20,601 | 0 | 0 | |
| Stitch Fix | COM CL A | 860897107 | 20,624 | 644,689 | SH | SOLE | 0 | 644,689 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 6,646 | 226,300 | SH | DFND | 1 | 226,300 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 10,099 | 343,871 | SH | DFND | 2 | 110,243 | 0 | 233,628 | |
| Stratasys | SHS | M85548101 | 2,505 | 85,298 | SH | DFND | 3 | 85,298 | 0 | 0 | |
| Stratasys | SHS | M85548101 | 4,247 | 144,600 | SH | SOLE | 0 | 144,600 | 0 | 0 | |
| Sunpower Corp | DBCV 4.000 1/1 | 867652AL3 | 3,557 | 3,978,000 | SH | DFND | 1 | 3,978,000 | 0 | 0 | |
| Sunpower Corp | DBCV 4.000 1/1 | 867652AL3 | 730 | 817,000 | SH | DFND | 3 | 817,000 | 0 | 0 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 77,899 | 2,044,597 | SH | DFND | 1 | 2,044,597 | 0 | 0 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 1,505,218 | 39,507,027 | SH | DFND | 2 | 9,863,840 | 0 | 29,643,187 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 23,504 | 616,905 | SH | DFND | 3 | 268,391 | 0 | 348,514 | |
| TAL Education Group ADR | ADS REPSTG COM | 874080104 | 157,812 | 4,142,043 | SH | SOLE | 0 | 2,030,324 | 0 | 2,111,719 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 53,580 | 1,073,316 | SH | DFND | 1 | 1,073,316 | 0 | 0 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 182,820 | 3,662,250 | SH | DFND | 2 | 2,880,392 | 0 | 781,858 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 37,851 | 758,234 | SH | DFND | 3 | 526,573 | 0 | 231,661 | |
| TD Ameritrade Holding Corp | COM | 87236Y108 | 108,640 | 2,176,278 | SH | SOLE | 0 | 2,108,735 | 0 | 67,543 | |
| TJX Companies | COM | 872540109 | 11,197 | 211,735 | SH | DFND | 1 | 211,735 | 0 | 0 | |
| TJX Companies | COM | 872540109 | 21,832 | 412,860 | SH | DFND | 2 | 401,552 | 0 | 11,308 | |
| TJX Companies | COM | 872540109 | 1,353 | 25,592 | SH | DFND | 3 | 14,025 | 0 | 11,567 | |
| TJX Companies | COM | 872540109 | 3,860 | 72,997 | SH | SOLE | 0 | 72,997 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 92,055 | 2,350,142 | SH | DFND | 1 | 2,350,142 | 0 | 0 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 726,479 | 18,546,827 | SH | DFND | 2 | 11,353,847 | 0 | 7,192,980 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 59,046 | 1,507,429 | SH | DFND | 3 | 1,078,501 | 0 | 428,928 | |
| TSMC ADR | SPONSORED ADR | 874039100 | 173,610 | 4,432,213 | SH | SOLE | 0 | 4,298,229 | 0 | 133,984 | |
| Tableau Software Class A | CL A | 87336U105 | 75,895 | 457,144 | SH | DFND | 1 | 457,144 | 0 | 0 | |
| Tableau Software Class A | CL A | 87336U105 | 69,487 | 418,544 | SH | DFND | 2 | 14,592 | 0 | 403,952 | |
| Tableau Software Class A | CL A | 87336U105 | 5,220 | 31,444 | SH | DFND | 3 | 18,415 | 0 | 13,029 | |
| Tableau Software Class A | CL A | 87336U105 | 145,480 | 876,278 | SH | SOLE | 0 | 876,278 | 0 | 0 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 14,523 | 225,100 | SH | DFND | 1 | 225,100 | 0 | 0 | |
| Tandem Diabetes Care | COM NEW | 875372203 | 13,523 | 209,600 | SH | SOLE | 0 | 209,600 | 0 | 0 | |
| Targa Resources | COM | 87612G101 | 102 | 2,599 | SH | DFND | 1 | 2,599 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 21,230 | 319,681 | SH | DFND | 1 | 319,681 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 20,639 | 310,780 | SH | DFND | 2 | 100,095 | 0 | 210,685 | |
| Teladoc | COM | 87918A105 | 5,306 | 79,894 | SH | DFND | 3 | 79,894 | 0 | 0 | |
| Teladoc | COM | 87918A105 | 11,499 | 173,152 | SH | SOLE | 0 | 173,152 | 0 | 0 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 6,181 | 412,355 | SH | DFND | 1 | 412,355 | 0 | 0 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 143,923 | 9,601,267 | SH | DFND | 2 | 6,178,243 | 0 | 3,423,024 | |
| Tencent Music Entertainment ADR | SPONSORED ADS | 88034P109 | 13,986 | 933,007 | SH | SOLE | 0 | 933,007 | 0 | 0 | |
| Teradyne | COM | 880770102 | 47,151 | 984,148 | SH | DFND | 1 | 984,148 | 0 | 0 | |
| Teradyne | COM | 880770102 | 229,487 | 4,789,969 | SH | DFND | 2 | 3,997,004 | 0 | 792,965 | |
| Teradyne | COM | 880770102 | 35,570 | 742,439 | SH | DFND | 3 | 517,514 | 0 | 224,925 | |
| Teradyne | COM | 880770102 | 100,448 | 2,096,601 | SH | SOLE | 0 | 2,026,789 | 0 | 69,812 | |
| TerraForm Power | CL A COM | 88104R209 | 60,269 | 4,214,600 | SH | DFND | 1 | 4,214,600 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 67 | 4,720 | SH | DFND | 2 | 4,720 | 0 | 0 | |
| TerraForm Power | CL A COM | 88104R209 | 3,152 | 220,405 | SH | DFND | 3 | 220,405 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 348,139 | 1,557,946 | SH | DFND | 1 | 1,557,946 | 0 | 0 | |
| Tesla Inc | COM | 88160R101 | 1,700,887 | 7,611,594 | SH | DFND | 2 | 2,138,317 | 0 | 5,473,277 | |
| Tesla Inc | COM | 88160R101 | 73,786 | 330,198 | SH | DFND | 3 | 205,675 | 0 | 124,523 | |
| Tesla Inc | COM | 88160R101 | 873,727 | 3,909,994 | SH | SOLE | 0 | 3,245,512 | 0 | 664,482 | |
| The Trade Desk | COM CL A | 88339J105 | 184,807 | 811,342 | SH | DFND | 1 | 811,342 | 0 | 0 | |
| The Trade Desk | COM CL A | 88339J105 | 246,254 | 1,081,106 | SH | DFND | 2 | 339,021 | 0 | 742,085 | |
| The Trade Desk | COM CL A | 88339J105 | 25,319 | 111,154 | SH | DFND | 3 | 78,627 | 0 | 32,527 | |
| The Trade Desk | COM CL A | 88339J105 | 117,381 | 515,325 | SH | SOLE | 0 | 506,627 | 0 | 8,698 | |
| Thermo Fisher Scientific | COM | 883556102 | 97,707 | 332,699 | SH | DFND | 1 | 332,699 | 0 | 0 | |
| Thermo Fisher Scientific | COM | 883556102 | 316,488 | 1,077,662 | SH | DFND | 2 | 819,711 | 0 | 257,951 | |
| Thermo Fisher Scientific | COM | 883556102 | 70,435 | 239,835 | SH | DFND | 3 | 168,101 | 0 | 71,734 | |
| Thermo Fisher Scientific | COM | 883556102 | 207,039 | 704,983 | SH | SOLE | 0 | 682,498 | 0 | 22,485 | |
| Trupanion | COM | 898202106 | 7,139 | 197,600 | SH | DFND | 1 | 197,600 | 0 | 0 | |
| Trupanion | COM | 898202106 | 11,471 | 317,494 | SH | DFND | 2 | 102,671 | 0 | 214,823 | |
| Trupanion | COM | 898202106 | 2,834 | 78,435 | SH | DFND | 3 | 78,435 | 0 | 0 | |
| Trupanion | COM | 898202106 | 26,556 | 735,000 | SH | SOLE | 0 | 735,000 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 16,295 | 157,791 | SH | DFND | 1 | 157,791 | 0 | 0 | |
| United Parcel Service | CL B | 911312106 | 1,034 | 10,016 | SH | DFND | 2 | 0 | 0 | 10,016 | |
| United Parcel Service | CL B | 911312106 | 15,921 | 154,168 | SH | SOLE | 0 | 154,168 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 2,356 | 248,000 | SH | DFND | 1 | 248,000 | 0 | 0 | |
| Unity Biotechnology Inc | COM | 91381U101 | 33,773 | 3,555,014 | SH | SOLE | 0 | 3,555,014 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 7,624 | 474,100 | SH | DFND | 1 | 474,100 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 6,593 | 410,000 | SH | DFND | 2 | 131,800 | 0 | 278,200 | |
| Upwork Inc | COM | 91688F104 | 1,611 | 100,200 | SH | DFND | 3 | 100,200 | 0 | 0 | |
| Upwork Inc | COM | 91688F104 | 4,822 | 299,900 | SH | SOLE | 0 | 299,900 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 2,665 | 1,211,500 | SH | DFND | 1 | 1,211,500 | 0 | 0 | |
| Uxin ADR | ADS | 91818X108 | 1,242 | 564,600 | SH | SOLE | 0 | 564,600 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 33,498 | 2,492,400 | SH | DFND | 1 | 2,492,400 | 0 | 0 | |
| Vale SA ADR | ADR | 91912E105 | 210,892 | 15,691,400 | SH | DFND | 2 | 6,158,200 | 0 | 9,533,200 | |
| Varian Medical Systems Inc | COM | 92220P105 | 9,861 | 72,439 | SH | DFND | 2 | 72,439 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 7,171 | 586,854 | SH | DFND | 1 | 586,854 | 0 | 0 | |
| Veeco Instruments | COM | 922417100 | 2,668 | 218,299 | SH | DFND | 2 | 67,206 | 0 | 151,093 | |
| Veeco Instruments | COM | 922417100 | 664 | 54,328 | SH | DFND | 3 | 54,328 | 0 | 0 | |
| Verisk Analytics | COM | 92345Y106 | 11,625 | 79,376 | SH | DFND | 2 | 79,376 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 146,941 | 846,677 | SH | DFND | 1 | 846,677 | 0 | 0 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 477,868 | 2,753,487 | SH | DFND | 2 | 2,072,953 | 0 | 680,534 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 107,436 | 619,049 | SH | DFND | 3 | 433,631 | 0 | 185,418 | |
| Visa Inc-Class A Shares | COM CL A | 92826C839 | 310,684 | 1,790,172 | SH | SOLE | 0 | 1,732,433 | 0 | 57,739 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 2,718 | 571,000 | SH | DFND | 1 | 571,000 | 0 | 0 | |
| Voya Prime Rate Trust | SH BEN INT | 92913A100 | 921 | 193,400 | SH | DFND | 3 | 193,400 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 14,018 | 168,140 | SH | DFND | 1 | 168,140 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 19 | 225 | SH | DFND | 2 | 225 | 0 | 0 | |
| WEC Energy Group | COM | 92939U106 | 577 | 6,925 | SH | DFND | 3 | 6,925 | 0 | 0 | |
| Wabtec | COM | 929740108 | 40,988 | 571,180 | SH | DFND | 1 | 571,180 | 0 | 0 | |
| Wabtec | COM | 929740108 | 137,825 | 1,920,634 | SH | DFND | 2 | 1,484,502 | 0 | 436,132 | |
| Wabtec | COM | 929740108 | 29,075 | 405,165 | SH | DFND | 3 | 280,903 | 0 | 124,262 | |
| Wabtec | COM | 929740108 | 82,978 | 1,156,330 | SH | SOLE | 0 | 1,119,149 | 0 | 37,181 | |
| Waters | COM | 941848103 | 77,560 | 360,341 | SH | DFND | 1 | 360,341 | 0 | 0 | |
| Waters | COM | 941848103 | 250,228 | 1,162,554 | SH | DFND | 2 | 896,670 | 0 | 265,884 | |
| Waters | COM | 941848103 | 55,713 | 258,843 | SH | DFND | 3 | 179,036 | 0 | 79,807 | |
| Waters | COM | 941848103 | 155,329 | 721,655 | SH | SOLE | 0 | 698,806 | 0 | 22,849 | |
| Watsco Inc | COM | 942622200 | 94,573 | 578,322 | SH | DFND | 1 | 578,322 | 0 | 0 | |
| Watsco Inc | COM | 942622200 | 100,516 | 614,666 | SH | DFND | 2 | 122,054 | 0 | 492,612 | |
| Watsco Inc | COM | 942622200 | 3,263 | 19,953 | SH | DFND | 3 | 13,298 | 0 | 6,655 | |
| Watsco Inc | COM | 942622200 | 39,862 | 243,761 | SH | SOLE | 0 | 243,761 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 235,907 | 1,615,802 | SH | DFND | 1 | 1,615,802 | 0 | 0 | |
| Wayfair Inc Class A | CL A | 94419L101 | 239,618 | 1,641,218 | SH | DFND | 2 | 122,970 | 0 | 1,518,248 | |
| Wayfair Inc Class A | CL A | 94419L101 | 15,185 | 104,010 | SH | DFND | 3 | 91,320 | 0 | 12,690 | |
| Wayfair Inc Class A | CL A | 94419L101 | 92,131 | 631,035 | SH | SOLE | 0 | 631,035 | 0 | 0 | |
| Weibo Corp SPON ADR | SPONSORED ADR | 948596101 | 1,146 | 26,310 | SH | DFND | 3 | 0 | 0 | 26,310 | |
| Wipro Ltd ADR | SPON ADR 1 SH | 97651M109 | 657 | 151,701 | SH | DFND | 2 | 100,842 | 0 | 50,859 | |
| Wix Com | SHS | M98068105 | 346,712 | 2,439,915 | SH | DFND | 2 | 717,530 | 0 | 1,722,385 | |
| Workday Inc | CL A | 98138H101 | 93,366 | 454,158 | SH | DFND | 1 | 454,158 | 0 | 0 | |
| Workday Inc | CL A | 98138H101 | 547,529 | 2,663,337 | SH | DFND | 2 | 972,791 | 0 | 1,690,546 | |
| Workday Inc | CL A | 98138H101 | 28,417 | 138,229 | SH | DFND | 3 | 61,239 | 0 | 76,990 | |
| Workday Inc | CL A | 98138H101 | 363,964 | 1,770,427 | SH | SOLE | 0 | 1,293,634 | 0 | 476,793 | |
| Xylem | COM | 98419M100 | 6,617 | 79,108 | SH | DFND | 1 | 79,108 | 0 | 0 | |
| Xylem | COM | 98419M100 | 8,260 | 98,761 | SH | DFND | 2 | 60,963 | 0 | 37,798 | |
| Xylem | COM | 98419M100 | 1,009 | 12,064 | SH | DFND | 3 | 12,064 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 70,333 | 3,500,873 | SH | DFND | 1 | 3,500,873 | 0 | 0 | |
| Yext Inc | COM | 98585N106 | 60,715 | 3,022,136 | SH | DFND | 2 | 351,388 | 0 | 2,670,748 | |
| Yext Inc | COM | 98585N106 | 6,094 | 303,343 | SH | DFND | 3 | 274,568 | 0 | 28,775 | |
| Yext Inc | COM | 98585N106 | 33,855 | 1,685,158 | SH | SOLE | 0 | 1,685,158 | 0 | 0 | |
| Zai Lab ADR | ADR | 98887Q104 | 20,901 | 599,400 | SH | DFND | 1 | 599,400 | 0 | 0 | |
| Zai Lab ADR | ADR | 98887Q104 | 40,679 | 1,166,583 | SH | DFND | 2 | 648,500 | 0 | 518,083 | |
| Zai Lab ADR | ADR | 98887Q104 | 4,784 | 137,200 | SH | DFND | 3 | 28,000 | 0 | 109,200 | |
| Zai Lab ADR | ADR | 98887Q104 | 6,388 | 183,200 | SH | SOLE | 0 | 183,200 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 8,432 | 184,269 | SH | DFND | 1 | 184,269 | 0 | 0 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 33,385 | 729,578 | SH | DFND | 2 | 426,413 | 0 | 303,165 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 3,633 | 79,397 | SH | DFND | 3 | 55,427 | 0 | 23,970 | |
| Zillow Group Inc Class A | CL A | 98954M101 | 18,131 | 396,221 | SH | SOLE | 0 | 383,402 | 0 | 12,819 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 103,980 | 2,241,422 | SH | DFND | 1 | 2,241,422 | 0 | 0 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 225,189 | 4,854,251 | SH | DFND | 2 | 3,245,849 | 0 | 1,608,402 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 54,963 | 1,184,792 | SH | DFND | 3 | 885,449 | 0 | 299,343 | |
| Zillow Group Inc Class C | CL C CAP STK | 98954M200 | 152,348 | 3,284,060 | SH | SOLE | 0 | 3,199,651 | 0 | 84,409 | |
| Zoom Video Communications Inc | CL A | 98980L101 | 26,637 | 300,000 | SH | SOLE | 0 | 300,000 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 7,418 | 484,179 | SH | DFND | 1 | 484,179 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 5,071 | 330,987 | SH | DFND | 2 | 106,503 | 0 | 224,484 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 1,288 | 84,067 | SH | DFND | 3 | 84,067 | 0 | 0 | |
| Zuora Inc Class A | COM CL A | 98983V106 | 3,758 | 245,311 | SH | SOLE | 0 | 245,311 | 0 | 0 | |
| iRobot | COM | 462726100 | 14,044 | 153,254 | SH | DFND | 1 | 153,254 | 0 | 0 | |
| iRobot | COM | 462726100 | 17,983 | 196,239 | SH | DFND | 2 | 64,151 | 0 | 132,088 | |
| iRobot | COM | 462726100 | 6,140 | 66,999 | SH | DFND | 3 | 58,199 | 0 | 8,800 | |
| iRobot | COM | 462726100 | 30,217 | 329,739 | SH | SOLE | 0 | 329,739 | 0 | 0 | |