The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ADAMAS PHARMACEUTICALS INC | COM | 00548A106 | 16,740 | 2,700,000 | SH | DFND | 1 | 2,700,000 | 0 | 0 | |
| AILERON THERAPEUTICS INC | COM | 00887A105 | 864 | 1,200,000 | SH | DFND | 1 | 1,200,000 | 0 | 0 | |
| ALIMERA SCIENCES INC | COM | 016259103 | 5,194 | 5,836,000 | SH | DFND | 1 | 5,836,000 | 0 | 0 | |
| AMAG PHARMACEUTICALS INC | COM | 00163U106 | 37,962 | 3,800,000 | SH | DFND | 1 | 3,800,000 | 0 | 0 | |
| AMAZON COM INC | COM | 023135106 | 7,575 | 4,000 | SH | DFND | 1 | 4,000 | 0 | 0 | |
| ANTARES PHARMA INC | COM | 036642106 | 19,740 | 6,000,000 | SH | DFND | 1 | 6,000,000 | 0 | 0 | |
| ASSEMBLY BIOSCIENCES INC | COM | 045396108 | 26,980 | 2,000,000 | SH | DFND | 1 | 2,000,000 | 0 | 0 | |
| AYTU BIOSCIENCE INC | COM PAR | 054754700 | 3,780 | 2,000,000 | SH | DFND | 1 | 2,000,000 | 0 | 0 | |
| BELLEROPHON THERAPEUTICS INC | COM | 078771102 | 1,714 | 2,860,000 | SH | DFND | 1 | 2,860,000 | 0 | 0 | |
| BIG LOTS INC | COM | 089302103 | 2,146 | 75,000 | SH | DFND | 1 | 75,000 | 0 | 0 | |
| BIOGEN INC | COM | 09062X103 | 6,548 | 28,000 | SH | DFND | 1 | 28,000 | 0 | 0 | |
| BIOHAVEN PHARMACTL HLDG CO L | COM | G11196105 | 7,006 | 160,000 | SH | DFND | 1 | 160,000 | 0 | 0 | |
| BLUEBIRD BIO INC | COM | 09609G100 | 12,720 | 100,000 | SH | DFND | 1 | 100,000 | 0 | 0 | |
| BURLINGTON STORES INC | COM | 122017106 | 38,114 | 224,000 | SH | DFND | 1 | 224,000 | 0 | 0 | |
| CANADA GOOSE HOLDINGS INC | SHS SUB VTG | 135086106 | 8,443 | 218,000 | SH | DFND | 1 | 218,000 | 0 | 0 | |
| CARMAX INC | COM | 143130102 | 9,551 | 110,000 | SH | DFND | 1 | 110,000 | 0 | 0 | |
| CASTLE BRANDS INC | COM | 148435100 | 464 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
| CATALYST PHARMACEUTICALS INC | COM | 14888U101 | 19,200 | 5,000,000 | SH | DFND | 1 | 5,000,000 | 0 | 0 | |
| CELGENE CORP | COM | 151020104 | 36,976 | 400,000 | SH | DFND | 1 | 400,000 | 0 | 0 | |
| CELLECTIS S A | SPONSORED ADS | 15117K103 | 12,480 | 800,000 | SH | DFND | 1 | 800,000 | 0 | 0 | |
| CERECOR INC | COM | 15671L109 | 100,255 | 18,429,285 | SH | DFND | 1 | 18,429,285 | 0 | 0 | |
| CLOVIS ONCOLOGY INC | COM | 189464100 | 32,946 | 2,215,600 | SH | Call | DFND | 1 | 2,215,600 | 0 | 0 |
| DAVE & BUSTERS ENTMT INC | COM | 238337109 | 2,024 | 50,000 | SH | DFND | 1 | 50,000 | 0 | 0 | |
| DEL FRISCOS RESTAURANT GROUP | COM | 245077102 | 48,755 | 6,125,000 | SH | DFND | 1 | 6,125,000 | 0 | 0 | |
| DIPLOMAT PHARMACY INC | COM | 25456K101 | 19,488 | 3,200,000 | SH | DFND | 1 | 3,200,000 | 0 | 0 | |
| DROPBOX INC | CL A | 26210C104 | 23,798 | 950,000 | SH | DFND | 1 | 950,000 | 0 | 0 | |
| DYNATRONICS CORP | COM NEW | 268157401 | 950 | 576,000 | SH | DFND | 1 | 576,000 | 0 | 0 | |
| EDGEWELL PERS CARE CO | COM | 28035Q102 | 41,503 | 1,540,000 | SH | DFND | 1 | 1,540,000 | 0 | 0 | |
| ENANTA PHARMACEUTICALS INC | COM | 29251M106 | 32,064 | 380,000 | SH | DFND | 1 | 380,000 | 0 | 0 | |
| ENERGIZER HLDGS INC NEW | COM | 29272W109 | 52,087 | 1,348,000 | SH | DFND | 1 | 1,348,000 | 0 | 0 | |
| EYEGATE PHARMACEUTICALS INC | COM | 30233M107 | 4,275 | 17,812,500 | SH | DFND | 1 | 17,812,500 | 0 | 0 | |
| FIVE BELOW INC | COM | 33829M101 | 25,564 | 213,000 | SH | DFND | 1 | 213,000 | 0 | 0 | |
| FOOT LOCKER INC | COM | 344849104 | 6,288 | 150,000 | SH | DFND | 1 | 150,000 | 0 | 0 | |
| FRONTDOOR INC | COM | 35905A109 | 21,775 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
| HAIN CELESTIAL GROUP INC | CALL | 405217100 | 43,800 | 2,000,000 | SH | Call | DFND | 1 | 2,000,000 | 0 | 0 |
| INCYTE CORP | COM | 45337C102 | 19,371 | 228,000 | SH | DFND | 1 | 228,000 | 0 | 0 | |
| JACK IN THE BOX INC | COM | 466367109 | 12,209 | 150,000 | SH | DFND | 1 | 150,000 | 0 | 0 | |
| LOWES COS INC | COM | 548661107 | 34,612 | 343,000 | SH | DFND | 1 | 343,000 | 0 | 0 | |
| LULULEMON ATHLETICA INC | COM | 550021109 | 9,731 | 54,000 | SH | DFND | 1 | 54,000 | 0 | 0 | |
| MADRIGAL PHARMACEUTICALS INC | COM | 558868105 | 42,762 | 408,000 | SH | DFND | 1 | 408,000 | 0 | 0 | |
| MALLINCKRODT PUB LTD CO | SHS | G5785G107 | 33,048 | 3,600,000 | SH | Call | DFND | 1 | 3,600,000 | 0 | 0 |
| MEDIGUS LTD | *W EXP 07/23/202 | 58471G128 | 1,533 | 1,285,715 | SH | DFND | 1 | 1,285,715 | 0 | 0 | |
| PARATEK PHARMACEUTICALS INC | COM | 699374302 | 9,887 | 2,478,000 | SH | DFND | 1 | 2,478,000 | 0 | 0 | |
| PLANET FITNESS INC | CL A | 72703H101 | 19,124 | 264,000 | SH | DFND | 1 | 264,000 | 0 | 0 | |
| REGENERON PHARMACEUTICALS | COM | 75886F107 | 38,812 | 124,000 | SH | DFND | 1 | 124,000 | 0 | 0 | |
| RESTAURANT BRANDS INTL INC | COM | 76131D103 | 12,726 | 183,000 | SH | DFND | 1 | 183,000 | 0 | 0 | |
| RH | COM | 74967X103 | 25,894 | 224,000 | SH | DFND | 1 | 224,000 | 0 | 0 | |
| SKECHERS U S A INC | CL A | 830566105 | 7,935 | 252,000 | SH | DFND | 1 | 252,000 | 0 | 0 | |
| SMUCKER J M CO | COM NEW | 832696405 | 25,803 | 224,000 | SH | DFND | 1 | 224,000 | 0 | 0 | |
| SPARK THERAPEUTICS INC | COM | 84652J103 | 6,962 | 68,000 | SH | DFND | 1 | 68,000 | 0 | 0 | |
| SPDR S&P 500 ETF TR | TR UNIT | 78462F103 | 395,550 | 1,350,000 | SH | Put | DFND | 1 | 1,350,000 | 0 | 0 |
| SPOTIFY TECHNOLOGY S A | SHS | L8681T102 | 7,019 | 48,000 | SH | DFND | 1 | 48,000 | 0 | 0 | |
| STRONGBRIDGE BIOPHARMA PLC | SHS USD | G85347105 | 4,945 | 1,580,000 | SH | DFND | 1 | 1,580,000 | 0 | 0 | |
| TAPESTRY INC | COM | 876030107 | 3,173 | 100,000 | SH | DFND | 1 | 100,000 | 0 | 0 | |
| TARGET CORP | COM | 87612E106 | 8,055 | 93,000 | SH | DFND | 1 | 93,000 | 0 | 0 | |
| UNITED THERAPEUTICS CORP DEL | COM | 91307C102 | 25,291 | 324,000 | SH | DFND | 1 | 324,000 | 0 | 0 | |
| VALERITAS HLDGS INC | COM | 91914N301 | 2,777 | 1,060,000 | SH | DFND | 1 | 1,060,000 | 0 | 0 | |
| VANDA PHARMACEUTICALS INC | COM | 921659108 | 44,496 | 3,158,000 | SH | DFND | 1 | 3,158,000 | 0 | 0 | |
| VOYAGER THERAPEUTICS INC | COM | 92915B106 | 25,478 | 936,000 | SH | DFND | 1 | 936,000 | 0 | 0 | |
| WELBILT INC | COM | 949090104 | 36,606 | 2,192,000 | SH | DFND | 1 | 2,192,000 | 0 | 0 | |
| ZAFGEN INC | COM | 98885E103 | 2,592 | 2,178,000 | SH | DFND | 1 | 2,178,000 | 0 | 0 | |