The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ACCELERON PHARMA INC | COM | 00434H108 | 72,618 | 1,369,625 | SH | DFND | 1 | 1,369,625 | 0 | 0 | |
| ADAPTHEALTH CORP | COM CL A | 00653Q102 | 188,855 | 17,199,888 | SH | DFND | 1 | 17,199,888 | 0 | 0 | |
| ADDUS HOMECARE CORP | COM | 006739106 | 19,241 | 197,915 | SH | DFND | 1 | 197,915 | 0 | 0 | |
| ADVERUM BIOTECHNOLOGIES INC | COM | 00773U108 | 2,435 | 211,343 | SH | DFND | 1 | 211,343 | 0 | 0 | |
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 42,835 | 1,772,255 | SH | DFND | 1 | 1,772,255 | 0 | 0 | |
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 2,509 | 103,800 | SH | Put | DFND | 1 | 103,800 | 0 | 0 |
| ALECTOR INC | COM | 014442107 | 35,783 | 2,076,812 | SH | DFND | 1 | 2,076,812 | 0 | 0 | |
| ALPINE IMMUNE SCIENCES INC | COM | 02083G100 | 956 | 248,992 | SH | DFND | 1 | 248,992 | 0 | 0 | |
| ARDELYX INC | COM | 039697107 | 52,567 | 7,004,253 | SH | DFND | 1 | 7,004,253 | 0 | 0 | |
| ARGENX SE | SPONSORED ADR | 04016X101 | 29,536 | 184,000 | SH | DFND | 1 | 184,000 | 0 | 0 | |
| ARVINAS INC | COM | 04335A105 | 44,716 | 1,088,234 | SH | DFND | 1 | 1,088,234 | 0 | 0 | |
| ATRICURE INC | COM | 04963C209 | 9,518 | 292,777 | SH | DFND | 1 | 292,777 | 0 | 0 | |
| AUDENTES THERAPEUTICS INC | COM | 05070R104 | 29,555 | 493,901 | SH | DFND | 1 | 493,901 | 0 | 0 | |
| AVROBIO INC | COM | 05455M100 | 23,451 | 1,164,970 | SH | DFND | 1 | 1,164,970 | 0 | 0 | |
| AXONICS MODULATION TECH INC | COM | 05465P101 | 23,219 | 837,945 | SH | DFND | 1 | 837,945 | 0 | 0 | |
| BIOCRYST PHARMACEUTICALS | COM | 09058V103 | 21,994 | 6,375,143 | SH | DFND | 1 | 6,375,143 | 0 | 0 | |
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 45,255 | 564,914 | SH | DFND | 1 | 564,914 | 0 | 0 | |
| BROOKDALE SR LIVING INC | COM | 112463104 | 52,514 | 7,223,419 | SH | DFND | 1 | 7,223,419 | 0 | 0 | |
| CABALETTA BIO INC | COM | 12674W109 | 22,750 | 1,628,504 | SH | DFND | 1 | 1,628,504 | 0 | 0 | |
| CENTENE CORP DEL | COM | 15135B101 | 69,685 | 1,108,400 | SH | DFND | 1 | 1,108,400 | 0 | 0 | |
| CLOVIS ONCOLOGY INC | NOTE 2.500% 9/1 | 189464AB6 | 42,905 | 49,064,000 | PRN | DFND | 1 | 49,064,000 | 0 | 0 | |
| CONSTELLATION PHARMCETICLS I | COM | 210373106 | 25,911 | 550,000 | SH | DFND | 1 | 550,000 | 0 | 0 | |
| DBV TECHNOLOGIES S A | SPONSORED ADR | 23306J101 | 50,889 | 4,756,000 | SH | DFND | 1 | 4,756,000 | 0 | 0 | |
| DECIPHERA PHARMACEUTICALS IN | COM | 24344T101 | 19,170 | 308,000 | SH | DFND | 1 | 308,000 | 0 | 0 | |
| DEXCOM INC | NOTE 0.750%12/0 | 252131AH0 | 50,441 | 34,000,000 | SH | DFND | 1 | 34,000,000 | 0 | 0 | |
| EDITAS MEDICINE INC | COM | 28106W103 | 34,313 | 1,158,841 | SH | DFND | 1 | 1,158,841 | 0 | 0 | |
| EHEALTH INC | COM | 28238P109 | 19,600 | 204,000 | SH | DFND | 1 | 204,000 | 0 | 0 | |
| FATE THERAPEUTICS INC | COM | 31189P102 | 39,191 | 2,002,605 | SH | DFND | 1 | 2,002,605 | 0 | 0 | |
| FORTY SEVEN INC | COM | 34983P104 | 17,598 | 447,000 | SH | DFND | 1 | 447,000 | 0 | 0 | |
| FREQUENCY THERAPEUTICS INC | COM | 35803L108 | 24,869 | 1,418,665 | SH | DFND | 1 | 1,418,665 | 0 | 0 | |
| GLOBAL BLOOD THERAPEUTICS IN | COM | 37890U108 | 19,952 | 251,000 | SH | DFND | 1 | 251,000 | 0 | 0 | |
| HOMOLOGY MEDICINES INC | COM | 438083107 | 108,585 | 5,245,638 | SH | DFND | 1 | 5,245,638 | 0 | 0 | |
| HORIZON PHARMA INVT LTD | NOTE 2.500% 3/1 | 44052TAB7 | 191,529 | 144,832,000 | PRN | DFND | 1 | 144,832,000 | 0 | 0 | |
| HORIZON THERAPEUTICS PUB LTD | SHS | G46188101 | 171,672 | 4,742,311 | SH | DFND | 1 | 4,742,311 | 0 | 0 | |
| HUMANA INC | COM | 444859102 | 30,055 | 82,000 | SH | DFND | 1 | 82,000 | 0 | 0 | |
| IMMUNOMEDICS INC | COM | 452907108 | 36,451 | 1,722,618 | SH | DFND | 1 | 1,722,618 | 0 | 0 | |
| INOGEN INC | COM | 45780L104 | 2,529 | 37,016 | SH | DFND | 1 | 37,016 | 0 | 0 | |
| INTERCEPT PHARMACEUTICALS IN | NOTE 3.250% 7/0 | 45845PAA6 | 58,256 | 57,791,000 | PRN | DFND | 1 | 57,791,000 | 0 | 0 | |
| INTERCEPT PHARMACEUTICALS IN | NOTE 2.000% 5/1 | 45845PAB4 | 4,632 | 3,500,000 | SH | DFND | 1 | 3,500,000 | 0 | 0 | |
| INTERSECT ENT INC | COM | 46071F103 | 69,646 | 2,797,033 | SH | DFND | 1 | 2,797,033 | 0 | 0 | |
| ITAMAR MED LTD | SPONSORED ADS | 465437101 | 4,043 | 314,136 | SH | DFND | 1 | 314,136 | 0 | 0 | |
| IVERIC BIO INC | COM | 46583P102 | 8,580 | 1,000,000 | SH | DFND | 1 | 1,000,000 | 0 | 0 | |
| KEMPHARM INC | COM | 488445107 | 196 | 517,692 | SH | DFND | 1 | 517,692 | 0 | 0 | |
| KODIAK SCIENCES INC | COM | 50015M109 | 14,390 | 200,000 | SH | DFND | 1 | 200,000 | 0 | 0 | |
| MALLINCKRODT PUB LTD CO | SHS | G5785G107 | 14,053 | 4,026,750 | SH | DFND | 1 | 4,026,750 | 0 | 0 | |
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 22,422 | 174,000 | SH | DFND | 1 | 174,000 | 0 | 0 | |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 84,567 | 3,448,912 | SH | DFND | 1 | 3,448,912 | 0 | 0 | |
| MOLINA HEALTHCARE INC | COM | 60855R100 | 20,141 | 148,433 | SH | DFND | 1 | 148,433 | 0 | 0 | |
| MYLAN N V | SHS EURO | N59465109 | 163,850 | 8,151,754 | SH | DFND | 1 | 8,151,754 | 0 | 0 | |
| MYOKARDIA INC | COM | 62857M105 | 57,506 | 789,000 | SH | DFND | 1 | 789,000 | 0 | 0 | |
| NEOS THERAPEUTICS INC | COM | 64052L106 | 485 | 320,993 | SH | DFND | 1 | 320,993 | 0 | 0 | |
| NEURONETICS INC | COM | 64131A105 | 4,827 | 1,075,000 | SH | DFND | 1 | 1,075,000 | 0 | 0 | |
| NEVRO CORP | NOTE 1.750% 6/0 | 64157FAA1 | 154,250 | 115,776,000 | PRN | DFND | 1 | 115,776,000 | 0 | 0 | |
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 121,856 | 8,862,247 | SH | DFND | 1 | 8,862,247 | 0 | 0 | |
| ORTHOPEDIATRICS CORP | COM | 68752L100 | 10,573 | 225,000 | SH | DFND | 1 | 225,000 | 0 | 0 | |
| PROTEON THERAPEUTICS INC | COM | 74371L109 | 832 | 2,029,000 | SH | DFND | 1 | 2,029,000 | 0 | 0 | |
| PTC THERAPEUTICS INC | NOTE 3.000% 8/1 | 69366JAB7 | 28,400 | 24,877,000 | PRN | DFND | 1 | 24,877,000 | 0 | 0 | |
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 3,469 | 396,472 | SH | DFND | 1 | 396,472 | 0 | 0 | |
| RA PHARMACEUTICALS INC | COM | 74933V108 | 71,320 | 1,519,718 | SH | DFND | 1 | 1,519,718 | 0 | 0 | |
| REATA PHARMACEUTICALS INC | CL A | 75615P103 | 20,443 | 100,000 | SH | DFND | 1 | 100,000 | 0 | 0 | |
| REVANCE THERAPEUTICS INC | COM | 761330109 | 14,607 | 900,000 | SH | DFND | 1 | 900,000 | 0 | 0 | |
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 98,482 | 4,289,291 | SH | DFND | 1 | 4,289,291 | 0 | 0 | |
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 49,263 | 2,164,471 | SH | DFND | 1 | 2,164,471 | 0 | 0 | |
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 27,098 | 210,000 | SH | DFND | 1 | 210,000 | 0 | 0 | |
| SELECT MED HLDGS CORP | COM | 81619Q105 | 18,513 | 793,200 | SH | DFND | 1 | 793,200 | 0 | 0 | |
| SHOCKWAVE MED INC | COM | 82489T104 | 3,074 | 70,000 | SH | DFND | 1 | 70,000 | 0 | 0 | |
| SIENTRA INC | COM | 82621J105 | 37,795 | 4,227,680 | SH | DFND | 1 | 4,227,680 | 0 | 0 | |
| SILK ROAD MEDICAL INC | COM | 82710M100 | 51,665 | 1,279,480 | SH | DFND | 1 | 1,279,480 | 0 | 0 | |
| SPRINGWORKS THERAPEUTICS INC | COM | 85205L107 | 30,339 | 788,243 | SH | DFND | 1 | 788,243 | 0 | 0 | |
| SYROS PHARMACEUTICALS INC | COM | 87184Q107 | 8,768 | 1,268,946 | SH | DFND | 1 | 1,268,946 | 0 | 0 | |
| TANDEM DIABETES CARE INC | COM NEW | 875372203 | 81,150 | 1,361,345 | SH | DFND | 1 | 1,361,345 | 0 | 0 | |
| THERAPEUTICSMD INC COM STK | COM | 88338N107 | 5,445 | 2,250,000 | SH | DFND | 1 | 2,250,000 | 0 | 0 | |
| TURNING POINT THERAPEUTICS I | COM | 90041T108 | 22,798 | 366,000 | SH | DFND | 1 | 366,000 | 0 | 0 | |
| VERICEL CORP | COM | 92346J108 | 47,808 | 2,747,563 | SH | DFND | 1 | 2,747,563 | 0 | 0 | |
| X4 PHARMACEUTICALS INC | COM | 98420X103 | 4,809 | 449,437 | SH | DFND | 1 | 449,437 | 0 | 0 | |
| XERIS PHARMACEUTICALS INC | COM | 98422L107 | 18,212 | 2,583,291 | SH | DFND | 1 | 2,583,291 | 0 | 0 | |