The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 8,834 206,500 SH   SOLE   206,500 0 0
ACHILLION PHARMACEUTICALS INC COM 00448Q201 4,583 760,000 SH   SOLE   760,000 0 0
AMARIN CORP PLC SPONSORED ADR 023111206 14,258 665,000 SH   SOLE   665,000 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 23,162 4,085,000 SH   SOLE   4,085,000 0 0
AQUESTIVE THERAPEUTICS INC COM 03843E104 4,298 738,500 SH   SOLE   738,500 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 17,473 292,000 SH   SOLE   292,000 0 0
AVENUE THERAPEUTICS INC COM NEW 05360L205 9,936 1,035,000 SH   SOLE   1,035,000 0 0
AXOGEN INC COM 05463X106 12,523 700,000 SH   SOLE   700,000 0 0
BIOHAVEN PHARMACEUTICAL HLDG COM G11196105 8,983 165,000 SH   SOLE   165,000 0 0
BIOLINERX LTD SPONSORED ADR 09071M106 38 16,667 SH   SOLE   16,667 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 8,001 100,000 SH   SOLE   100,000 0 0
CERECOR INC COM 15671L109 11,808 2,190,674 SH   SOLE   2,190,674 0 0
CHEMOCENTRYX INC COM 16383L106 13,846 361,600 SH   SOLE   361,600 0 0
CODEXIS INC COM 192005106 22,286 1,400,000 SH   SOLE   1,400,000 0 0
CRINETICS PHARMACEUTICALS INC COM 22663K107 6,676 266,100 SH   SOLE   266,100 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 13,973 224,500 SH   SOLE   224,500 0 0
EDAP TMS SA SPONSORED ADR 268311107 7,908 1,785,000 SH   SOLE   1,785,000 0 0
EIDOS THERAPEUTICS INC COM 28249H104 18,109 315,550 SH   SOLE   315,550 0 0
EPIZYME INC COM 29428V104 34,051 1,384,200 SH   SOLE   1,384,200 0 0
ETON PHARMACEUTICALS INC COM 29772L108 10,580 1,469,456 SH   SOLE   1,469,456 0 0
FENNEC PHARMACEUTICALS INC COM 31447P100 78 12,000 SH   SOLE   12,000 0 0
FIBROGEN INC COM 31572Q808 6,262 146,000 SH   SOLE   146,000 0 0
FLEXION THERAPEUTICS INC COM 33938J106 8,601 415,500 SH   SOLE   415,500 0 0
FORTRESS BIOTECH INC COM 034960Q19 9,831 3,825,100 SH   SOLE   3,825,100 0 0
FORTY SEVEN INC COM 34983P104 22,126 562,000 SH   SOLE   562,000 0 0
HARROW HEALTH COM 45323A201 18,205 2,340,000 SH   SOLE   2,340,000 0 0
INTRA CELLULAR THERAPIES INC COM 46116X101 13,950 406,600 SH   SOLE   406,600 0 0
KADMON HOLDINGS INC COM 48283N106 4,260 940,373 SH   SOLE   940,373 0 0
MACROGENICS INC COM 556099109 2,181 200,500 SH   SOLE   200,500 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 6,728 449,950 SH   SOLE   449,950 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 17,018 1,381,300 SH   SOLE   1,381,300 0 0
OCULAR THERAPEUTIX INC COM 67576A100 20,175 5,107,500 SH   SOLE   5,107,500 0 0
ODONATE THERAPEUTICS INC COM 676079106 11,520 355,000 SH   SOLE   355,000 0 0
PROTEON THERAPEUTICS INC COM 74371L109 75 188,144 SH   SOLE   188,144 0 0
PTC THERAPEUTICS INC COM 69366J200 9,174 191,000 SH   SOLE   191,000 0 0
QUANTERIX CORP COM 74766Q101 3,124 132,200 SH   SOLE   132,200 0 0
RA PHARMACEUTICALS INC COM 74933V108 6,655 141,800 SH   SOLE   141,800 0 0
RADIUS HEALTH INC COM NEW 750469207 3,387 168,000 SH   SOLE   168,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 2,537 110,500 SH   SOLE   110,500 0 0
STEREOTAXIS INC COM NEW 85916J409 22,025 4,112,500 SH   SOLE   4,112,500 0 0
TELA BIO INC COM 872381108 2,266 175,000 SH   SOLE   175,000 0 0
TG THERAPEUTICS INC COM 88322Q108 6,434 579,651 SH   SOLE   579,651 0 0
TRICIDA INC COM 89610F101 7,303 194,000 SH   SOLE   194,000 0 0
TURNING POINT THERAPEUTICS INC COM 90041T108 21,210 340,500 SH   SOLE   340,500 0 0
UNIQURE NV SHS N90064101 15,049 210,000 SH   SOLE   210,000 0 0
XOMA CORP DEL COM NEW 98419J206 10,195 373,450 SH   SOLE   373,450 0 0
ZYMEWORKS INC COM 98985W102 7,956 175,000 SH   SOLE   175,000 0 0