The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 21,390 500,000 SH   SOLE   500,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 3,945 2,087,312 SH   SOLE   2,087,312 0 0
ANAPTYSBIO INC COM 032724106 31,949 1,966,100 SH   SOLE   1,966,100 0 0
ARCUS BIOSCIENCES INC COM 03969F109 7,372 729,905 SH   SOLE   729,905 0 0
ARGENX SE SPONSORED ADR 04016X101 32,444 202,117 SH   SOLE   202,117 0 0
ARVINAS INC COM 04335A105 55,022 1,339,069 SH   SOLE   1,339,069 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 48,864 2,388,268 SH   SOLE   2,388,268 0 0
ATRECA INC CL A COM 04965G109 22,917 1,481,411 SH   SOLE   1,481,411 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 26,422 312,500 SH Call SOLE   312,500 0 0
CHIASMA INC COM 16706W102 15,097 3,043,827 SH   SOLE   3,043,827 0 0
CORVUS PHARMACEUTICALS INC COM 221015100 4,013 737,612 SH   SOLE   737,612 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 4,926 1,811,000 SH   SOLE   1,811,000 0 0
CYTOMX THERAPEUTICS INC COM 23284F105 3,407 410,000 SH   SOLE   410,000 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 79,916 3,627,597 SH   SOLE   3,627,597 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 6,695 449,338 SH   SOLE   449,338 0 0
EVOLUS INC COM 30052C107 7,302 600,000 SH   SOLE   600,000 0 0
EXICURE INC COM 30205M101 10,136 3,544,186 SH   SOLE   3,544,186 0 0
FATE THERAPEUTICS INC COM 31189P102 8,833 451,354 SH   SOLE   451,354 0 0
FIBROGEN INC COM 31572Q808 29,015 676,500 SH Call SOLE   676,500 0 0
FIBROGEN INC COM 31572Q808 64,001 1,492,221 SH   SOLE   1,492,221 0 0
HARPOON THERAPEUTICS INC COM 41358P106 13,437 908,547 SH   SOLE   908,547 0 0
IGM BIOSCIENCES INC COM 449585108 3,816 100,000 SH   SOLE   100,000 0 0
INNATE PHARMA S A SPONSORED ADS 45781K204 29,273 4,545,454 SH   SOLE   4,545,454 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 5,914 213,647 SH   SOLE   213,647 0 0
IRONWOOD PHARMACEUTICALS INC COM CL A 46333X108 58,183 4,371,408 SH   SOLE   4,371,408 0 0
KURA ONCOLOGY INC COM 50127T109 58,327 4,241,953 SH   SOLE   4,241,953 0 0
MERUS N V COM N5749R100 24,192 1,718,200 SH   SOLE   1,718,200 0 0
MIRATI THERAPEUTICS INC COM 60468T105 8,376 65,000 SH   SOLE   65,000 0 0
MORPHIC HLDG INC COM 61775R105 36,977 2,154,845 SH   SOLE   2,154,845 0 0
NEOLEUKIN THERAPEUTICS INC COM 64049K104 48,244 3,915,880 SH   SOLE   3,915,880 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 9,177 2,535,212 SH   SOLE   2,535,212 0 0
PREVAIL THERAPEUTICS INC COM 74140Y101 35,591 2,248,306 SH   SOLE   2,248,306 0 0
PROTHENA CORP PLC SHS G72800108 149,224 9,426,640 SH   SOLE   9,426,640 0 0
RUBIUS THERAPEUTICS INC COM 78116T103 4,996 525,877 SH   SOLE   525,877 0 0
SAGE THERAPEUTICS INC COM 78667J108 12,515 173,364 SH   SOLE   173,364 0 0
SAVARA INC COM 805111101 6,418 1,432,664 SH   SOLE   1,432,664 0 0
SELECTA BIOSCIENCES INC COM 816212104 10,943 4,597,701 SH   SOLE   4,597,701 0 0
SURFACE ONCOLOGY INC COM 86877M209 2,447 1,301,713 SH   SOLE   1,301,713 0 0
TCR2 THERAPEUTICS INC COM 87808K106 3,420 239,500 SH   SOLE   239,500 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 11,171 261,554 SH   SOLE   261,554 0 0
UROVANT SCIENCES LTD SHS G9381B108 411 26,468 SH   SOLE   26,468 0 0
VERICEL CORP COM 92346J108 2,279 131,001 SH   SOLE   131,001 0 0
X4 PHARMACEUTICALS INC COM 98420X103 4,445 415,400 SH   SOLE   415,400 0 0
XENCOR INC COM 98401F105 86,029 2,501,557 SH   SOLE   2,501,557 0 0