The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AMAG PHARMACEUTICALS INC COM 00163U106 37,050 3,044,374 SH   SOLE 0 3,044,374 0 0
ABIOMED INC COM 003654100 96,241 564,168 SH   SOLE 0 564,168 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 81,512 1,905,374 SH   SOLE 0 1,905,374 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 113,143 3,380,441 SH   SOLE 0 3,380,441 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 427 73,500 SH   SOLE 0 73,500 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 94,967 878,100 SH   SOLE 0 878,100 0 0
ALIGN TECHNOLOGY INC COM 016255101 35,579 127,505 SH   SOLE 0 127,505 0 0
ALIMERA SCIENCES INC COM 016259103 1,523 200,919 SH   SOLE 0 200,919 0 0
AMICUS THERAPEUTICS INC COM 03152W109 72,212 7,413,920 SH   SOLE 0 7,413,920 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 170,887 2,021,136 SH   SOLE 0 2,021,136 0 0
CLOVIS ONCOLOGY INC COM 189464100 52,712 5,056,286 SH   SOLE 0 5,056,286 0 0
CYTOKINETICS INC COM 23282W605 1,312 123,686 SH   SOLE 0 123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 7,310 331,813 SH   SOLE 0 331,813 0 0
EPIZYME INC COM 29428V104 151,190 6,145,945 SH   SOLE 0 6,145,945 0 0
GILEAD SCIENCES INC COM 375558103 2,554 39,300 SH   SOLE 0 39,300 0 0
IDERA PHARMACEUTICALS INC COM 45168K405 140 77,044 SH   SOLE 0 77,044 0 0
IMMUNOMEDICS INC COM 452907108 125,335 5,923,195 SH   SOLE 0 5,923,195 0 0
INSMED INC COM 457669307 163,548 6,848,760 SH   SOLE 0 6,848,760 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 1,283 37,400 SH   SOLE 0 37,400 0 0
KALEIDO BIOSCIENCES INC COM 483347100 3,956 787,999 SH   SOLE 0 787,999 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 88,086 4,595,001 SH   SOLE 0 4,595,001 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 271 125,321 SH   SOLE 0 125,321 0 0
MELINTA THERAPEUTICS INC COM 58549G209 5 10,137 SH   SOLE 0 10,137 0 0
MINERVA NEUROSCIENCES INC COM 603380106 258 36,319 SH   SOLE 0 36,319 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 33,252 1,685,372 SH   SOLE 0 1,685,372 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 11,805 1,349,180 SH   SOLE 0 1,349,180 0 0
REVANCE THERAPEUTICS INC COM 761330109 1,438 88,590 SH   SOLE 0 88,590 0 0
RIGEL PHARMACEUTICALS INC COM 766559603 7,581 3,542,551 SH   SOLE 0 3,542,551 0 0
SAGE THERAPEUTICS INC COM 78667J108 47,183 653,594 SH   SOLE 0 653,594 0 0
SOPHIRIS BIO INC COM 83578Q209 91 247,000 SH   SOLE 0 247,000 0 0
STAAR SURGICAL CO COM 852312305 132,905 3,778,938 SH   SOLE 0 3,778,938 0 0
SUNESIS PHARMACEUTICALS INC COM 867328700 393 1,162,473 SH   SOLE 0 1,162,473 0 0
UNITED THERAPEUTICS CORP COM 91307C102 113,526 1,288,902 SH   SOLE 0 1,288,902 0 0
VANDA PHARMACEUTICALS INC COM 921659108 74,263 4,525,476 SH   SOLE 0 4,525,476 0 0
ZOGENIX INC COM 98978L204 1,538 29,500 SH   SOLE 0 29,500 0 0
PROTHENA CORP PLC COM G72800108 15,715 992,749 SH   SOLE 0 992,749 0 0
WRIGHT MEDICAL GROUP NV COM N96617118 75,074 2,463,055 SH   SOLE 0 2,463,055 0 0