Exhibit 99.1

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Auxilium Pharmaceuticals, Inc. Announces Third Quarter 2006

Financial Results

Q3 Net Revenues Up 57% versus Q3 of 2005

MALVERN, PA (October 31, 2006) – Auxilium Pharmaceuticals, Inc. (NASDAQ: AUXL) today announced financial results and operational highlights for the quarter and nine months ended September 30, 2006. For the third quarter of 2006, Auxilium reported net revenues of $17.6 million compared to net revenues of $11.2 million in the third quarter of 2005.

“We made tremendous progress during the quarter toward achieving our long term goals by taking control of Auxilium’s main value drivers, our marketed product, Testim^®, and our company transforming injectable enzyme, AA4500,” said Mr. Armando Anido, Chief Executive Officer and President. “I am pleased to report that we successfully completed our sales force expansion to support the continued growth of Testim and we completed our initial engineering batch of AA4500 in the state of the art manufacturing facility we leased in September.”

Third Quarter 2006 Highlights:

Recent Event:

Third Quarter Financial Detail

For the quarter ended September 30, 2006, Auxilium reported net revenues of $17.6 million, an increase of 57% over net revenues of $11.2 million reported for the comparable period of 2005. The net loss for the third quarter of 2006 was $(11.8) million, or $(0.39) per share, compared to a net loss of $(7.1) million, or $(0.24) per share, reported for the third quarter of 2005. As of January 1, 2006, the Company implemented Statement of Financial Accounting Standard No. 123R (SFAS 123R) which requires companies to estimate on grant date the fair value of share based payment awards to employees and directors, and record compensation expense in their financial statements. The Company’s financial statements for periods prior to 2006 do not include any SFAS 123R costs related to employee or director stock options. As a result of adoption of SFAS 123R, the net loss for the third quarter of 2006 includes additional stock compensation expense of $0.9 million, or $(0.03) per share.

Auxilium’s gross margin on net revenues was 74.6% for the third quarter of 2006 and 70.8% for the third quarter of 2005. Gross margin reflects the cost of product sold as well as royalty payments made to the Company’s licensor on the sales of Testim. The improvement in gross margin reflects the year-over-year price increases, a reduction in the royalty rate paid to the Company’s licensor, and manufacturing cost reductions.

Research and development costs for the third quarter of 2006 were $8.5 million compared with $4.5 million for the comparable year-ago period. The increase in research and development costs was primarily due to the increased spending for development and manufacturing scale up for AA4500 and investment in developing TestoFilm, offset by a reduction in spending on Phase IV studies for Testim.

Selling, general and administrative expenses totaled $17.1 million for the quarter ended September 30, 2006 compared with $10.7 million for the year-ago quarter. The increase was primarily due to higher investment in promotional spending for Testim, pre-launch marketing for AA4500, the $1.8 million cost to terminate Auxilium’s co-promotion agreement with Oscient Pharmaceuticals Corp., and the additional stock compensation expense resulting from the adoption of SFAS 123R.

In September, the Company closed an equity offering for the sale of 5.5 million shares of Auxilium common stock at $8.50 per share, netting $43.3 million to Auxilium after deducting offering expenses and placement agency fees. As of September 30, 2006, the Company had approximately 35.3 million shares of common stock outstanding plus outstanding warrants to purchase approximately 3.3 million shares of our common stock and 3.4 million outstanding employee stock options to purchase shares of common stock at varying prices.

At September 30, 2006, Auxilium had $67.4 million in cash, cash equivalents, and short-term investments compared to $33.3 million at June 30, 2006.

Year-to-Date September 30, 2006 Financial Detail

Net revenues for the nine months ended September 30, 2006 were $49.0 million compared to $29.9 million for the first nine months of 2005, a 64% increase. Net revenues for the first nine months of 2006 include a one-time benefit of $1.2 million recorded in the first quarter of 2006 upon adoption of the wholesaler method of revenue recognition. Excluding this one time increase, net revenues for the first nine months of 2006 increased 60% over the comparable 2005 period.

For the nine months ended September 30, 2006, Auxilium reported a net loss of $(33.2) million, or $(1.13) per share, compared to a net loss of $(27.2) million, or $(1.16) per share, for the first nine months of 2005. The net loss for the first nine months of 2006 was reduced by a one-time benefit of $0.7 million, or $0.02 per share, resulting from the change to the wholesaler method of revenue recognition. As a result of adoption of SFAS 123R, the net loss for the nine months ended September 30, 2006 also includes additional stock compensation expense of $1.6 million, or $(0.05) per share

Gross margin on net revenues was 74.0 % for the nine months ended September 30, 2006, compared to 69.0 % for the comparable 2005 period. Gross margin reflects the cost of product sold as well as royalty payments made to the Company’s licensor on the sales of Testim. The improvement in gross margin reflects the year-over-year price increases, a reduction in the royalty rate paid to the Company’s licensor, and manufacturing cost reductions.

Research and development costs for the nine months ended September 30, 2006 were $25.7 million compared with $17.9 in the year ago period. The increase in research and development expense in the first nine months of 2006 versus the comparable period of 2005 was primarily due to the increased spending for development and manufacturing scale up for AA4500 and investment in developing TestoFilm, offset by a reduction in spending on Phase IV studies for Testim.

Selling, general and administrative expenses totaled $45.5 million for the nine months ended September 30, 2006 compared with $30.4 million for the year-ago period. The

increase was primarily due to higher investment in promotional spending, including the costs associated with Auxilium’s co-promotion agreement with Oscient Pharmaceuticals Corp. which started in May 2005 and was terminated in September 2006 at a cost of $1.8 million, pre-launch marketing for AA4500, and the additional stock compensation expense resulting from the adoption of SFAS 123R.

Conference Call

Auxilium will hold a conference call today, October 31, at 10:00 a.m. EST, to provide an update on the business and discuss third quarter 2006 results. The conference call will be simultaneously web cast on Auxilium’s web site and archived for future review until November 14, 2006.

About Auxilium

Auxilium Pharmaceuticals, Inc. is a specialty biopharmaceutical company with a focus on developing and marketing to urologists, endocrinologists, orthopedists and select primary care physicians. Auxilium markets Testim^® 1%, a topical testosterone gel, for the treatment of hypogonadism through its approximately 180-person sales and marketing team. Auxilium has four projects in clinical development. Auxilium believes that AA4500, an injectable enzyme, has completed Phase II of development for the treatment of Dupuytren’s Contracture and is in Phase II of development for the treatment of Peyronie’s Disease and Frozen Shoulder Syndrome (Adhesive Capsulitis). Auxilium’s transmucosal film product candidate for the treatment of overactive bladder (AA4010) is in Phase I of development. The Company is currently seeking a partner to further develop this product candidate. Auxilium has two pain products using its transmucosal film delivery system in pre-clinical development. Auxilium has rights to six additional pain products and products for hormone replacement and urologic disease using its transmucosal film delivery system, and options to all indications using AA4500 for non-topical formulations. For additional information, visit http://www.auxilium.com.

SAFE HARBOR STATEMENT UNDER THE PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995

In addition to historical facts or statements of current condition, this release contains forward-looking statements within the meaning of the “Safe Harbor” provisions of The Private Securities Litigation Reform Act of 1995, including statements regarding the timing for the commencement of various clinical trials for Auxilium’s product candidates during 2006, Auxilium’s value drivers, the availability and allocation of resources, and the drivers of Testim sales and market share growth.

Forward-looking statements often address Auxilium’s expected future financial position or business strategy and plans and objectives of management for future operations, and often contain the words “believe,” “may,” “could,” “will,” “estimate,” “continue,” “anticipate,” “intend,” “should,” “plan,” “expect” and similar expressions. Forward-looking statements provide Auxilium’s current expectations or forecasts of future events. Auxilium’s performance and financial results could differ materially from those reflected in these forward-looking statements due to:

A more detailed list and description of the risks and uncertainties that Auxilium faces may be found under the heading “Risk Factors” in Auxilium’s Annual Report on Form 10-K for the year ended December 31, 2005 and in Auxilium’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2006, which are on file with the Securities and Exchange Commission. Given these risks and uncertainties, any or all of the forward-looking statements contained in this release may prove to be incorrect. Therefore, you should not rely on any such factors or forward-looking statements. Auxilium undertakes no obligation to update publicly any forward-looking statement.

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AUXILIUM PHARMACEUTICALS, INC.

Condensed Consolidated Statement of Operations

(In thousands, except share and per share amounts)

(Unaudited)

AUXILIUM PHARMACEUTICALS, INC.

Selected Consolidated Balance Sheet Data

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(Unaudited)