The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 3,802 42,305 SH   SOLE   42,305 0 0
AFFIMED N V COM N01045108 886 560,800 SH   SOLE   560,800 0 0
AGILE THERAPEUTICS INC COM 00847L100 1,324 711,756 SH   SOLE   711,756 0 0
AGILENT TECHNOLOGIES INC COM 00846U101 36 500 SH   SOLE   500 0 0
ALBIREO PHARMA INC COM 01345P106 1,277 78,029 SH   SOLE   78,029 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 14,016 3,504,062 SH   SOLE   3,504,062 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106 24,097 899,474 SH   SOLE   899,474 0 0
AQUESTIVE THERAPEUTICS INC COM 03843E104 657 300,000 SH   SOLE   300,000 0 0
ARTARA THERAPEUTICS INC COM 04300J107 747 32,478 SH   SOLE   32,478 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 31,023 275,494 SH   SOLE   275,494 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108 15,745 352,551 SH   SOLE   352,551 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100 1,258 210,013 SH   SOLE   210,013 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 15,085 7,542,372 SH   SOLE   7,542,372 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 465 122,702 SH   SOLE   122,702 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 3,620 106,385 SH   SOLE   106,385 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 12/30/2030 110122140 3 6,000 SH   SOLE   6,000 0 0
CHEMOCENTRYX INC COM 16383L106 23,305 580,011 SH   SOLE   580,011 0 0
COMMUNITY HEALTH SYS INC NEW COM 203668108 1,938 580,350 SH   SOLE   580,350 0 0
CYCLERION THERAPEUTICS INC COM 23255M105 893 337,145 SH   SOLE   337,145 0 0
CYTOKINETICS INC COM NEW 23282W605 2,142 181,700 SH   SOLE   181,700 0 0
DANAHER CORPORATION COM 235851102 32,419 233,957 SH   SOLE   233,957 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 17,048 414,081 SH   SOLE   414,081 0 0
DEXCOM INC COM 252131107 5,261 19,537 SH   SOLE   19,537 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 1,098 59,774 SH   SOLE   59,774 0 0
EHEALTH INC COM 28238P109 444 3,153 SH   SOLE   3,153 0 0
EIGER BIOPHARMACEUTICALS INC COM 28249U105 474 69,708 SH   SOLE   69,708 0 0
ENSIGN GROUP INC COM 29358P101 13,445 357,028 SH   SOLE   357,028 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 1,632 109,212 SH   SOLE   109,212 0 0
FATE THERAPEUTICS INC COM 31189P102 6,785 305,485 SH   SOLE   305,485 0 0
GENMARK DIAGNOSTICS INC COM 372309104 2,160 524,257 SH   SOLE   524,257 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 19,855 510,571 SH   SOLE   510,571 0 0
HCA HEALTHCARE INC COM 40412C101 9,075 101,000 SH   SOLE   101,000 0 0
HESKA CORP COM RESTRC NEW 42805E306 1,149 20,771 SH   SOLE   20,771 0 0
IGM BIOSCIENCES INC COM 449585108 549 9,770 SH   SOLE   9,770 0 0
ILLUMINA INC COM 452327109 46 170 SH   SOLE   170 0 0
IMMUNOVANT INC COM 45258J102 1,196 76,866 SH   SOLE   76,866 0 0
INFLARX NV COM N44821101 747 195,488 SH   SOLE   195,488 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 2,696 90,047 SH   SOLE   90,047 0 0
KADMON HLDGS INC COM 48283N106 4,087 975,350 SH   SOLE   975,350 0 0
LIQUIDIA TECHNOLOGIES INC COM 53635D202 1,152 244,637 SH   SOLE   244,637 0 0
MACROGENICS INC COM 556099109 535 91,998 SH   SOLE   91,998 0 0
MODEL N INC COM 607525102 8,313 374,284 SH   SOLE   374,284 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 3,986 146,550 SH   SOLE   146,550 0 0
MYOKARDIA INC COM 62857M105 1,301 27,752 SH   SOLE   27,752 0 0
OPTINOSE INC COM 68404V100 22 5,006 SH   SOLE   5,006 0 0
OTONOMY INC COM 68906L105 1,107 561,737 SH   SOLE   561,737 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 1,595 172,193 SH   SOLE   172,193 0 0
PENNANT GROUP INC COM 70805E109 3,996 282,181 SH   SOLE   282,181 0 0
PFENEX INC COM 717071104 408 46,293 SH   SOLE   46,293 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 492 58,251 SH   SOLE   58,251 0 0
RADIUS HEALTH INC COM NEW 750469207 3,914 301,073 SH   SOLE   301,073 0 0
SANOFI SPONSORED ADR 80105N105 8,288 189,578 SH   SOLE   189,578 0 0
SCPHARMACEUTICALS INC COM 810648105 980 132,419 SH   SOLE   132,419 0 0
SESEN BIO INC COM 817763105 729 1,300,000 SH   SOLE   1,300,000 0 0
TARO PHARMACEUTICAL INDS LTD SHS M8737E108 4,679 76,459 SH   SOLE   76,459 0 0
TELIGENT INC NEW COM 87960W104 1,082 3,862,903 SH   SOLE   3,862,903 0 0
TG THERAPEUTICS INC COM 88322Q108 24,218 2,461,137 SH   SOLE   2,461,137 0 0
XENON PHARMACEUTICALS INC COM 98420N105 812 71,591 SH   SOLE   71,591 0 0
ZOGENIX INC COM NEW 98978L204 49,793 2,013,467 SH   SOLE   2,013,467 0 0
AIR LEASE CORP PUT 00912X952 121 200 SH   SOLE   200 0 0
ALIGN TECHNOLOGY INC PUT 016255951 423 100 SH   SOLE   100 0 0
AMARIN CORP PLC CALL 023111906 374 10,236 SH   SOLE   10,236 0 0
AMARIN CORP PLC PUT 023111956 537 1,500 SH   SOLE   1,500 0 0
SPDR S&P 500 ETF TR PUT 78462F953 13,653 600 SH   SOLE   600 0 0
ZOGENIX INC CALL 98978L904 55 55 SH   SOLE   55 0 0