The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories Common 002824100 36,815 466,550 SH   SOLE   466,550 0 0
AbbVie Inc. Common 00287Y109 25,974 340,916 SH   SOLE   340,916 0 0
ABIOMED, Inc. Common 003654100 4,285 29,516 SH   SOLE   29,516 0 0
AC Immune SA Shares H00263105 1,187 171,813 SH   SOLE   171,813 0 0
Acadia Healthcare Company, Inc. Common 00404A109 2,408 131,200 SH   SOLE   131,200 0 0
ACADIA Pharmaceuticals Inc. Common 004225108 9,363 221,599 SH   SOLE   221,599 0 0
Acceleron Pharma Inc. Common 00434H108 3,649 40,606 SH   SOLE   40,606 0 0
Aerie Pharmaceuticals, Inc. Common 00771V108 900 66,688 SH   SOLE   66,688 0 0
Aerpio Pharmaceuticals, Inc. Common 00810B105 142 257,554 SH   SOLE   257,554 0 0
Agilent Technologies, Inc. Common 00846U101 3,762 52,525 SH   SOLE   52,525 0 0
Agios Pharmaceuticals, Inc. Common 00847X104 6,633 186,964 SH   SOLE   186,964 0 0
Alcon Inc. Ordinary Shares H01301128 1,864 36,686 SH   SOLE   36,686 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 37,113 413,326 SH   SOLE   413,326 0 0
Align Technology, Inc. Common 016255101 1,747 10,041 SH   SOLE   10,041 0 0
Alkermes plc Shares G01767105 2,450 169,930 SH   SOLE   169,930 0 0
Allakos Inc. Common 01671P100 2,865 64,397 SH   SOLE   64,397 0 0
Allergan plc Shares G0177J108 27,978 157,981 SH   SOLE   157,981 0 0
Allogene Therapeutics, Inc. Common 019770106 4,748 244,261 SH   SOLE   244,261 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 14,980 137,617 SH   SOLE   137,617 0 0
Amarin Corporation plc Sponsored ADR 023111206 2,415 603,791 SH   SOLE   603,791 0 0
AmerisourceBergen Corporation Common 03073E105 4,788 54,107 SH   SOLE   54,107 0 0
Amgen Inc. Common 031162100 121,612 599,871 SH   SOLE   599,871 0 0
Amicus Therapeutics, Inc. Common 03152W109 3,409 368,960 SH   SOLE   368,960 0 0
AnaptysBio, Inc. Common 032724106 1,671 118,261 SH   SOLE   118,261 0 0
Anthem, Inc. Common 036752103 14,887 65,568 SH   SOLE   65,568 0 0
Apellis Pharmaceuticals, Inc. Common 03753U106 4,648 173,494 SH   SOLE   173,494 0 0
ARCA biopharma, Inc. Common 00211Y506 100 36,068 SH   SOLE   36,068 0 0
Ardelyx, Inc. Common 039697107 3,455 607,698 SH   SOLE   607,698 0 0
Arena Pharmaceuticals, Inc. Common 040047607 1,176 28,002 SH   SOLE   28,002 0 0
argenx SE Sponsored ADR 04016X101 5,925 44,977 SH   SOLE   44,977 0 0
Arrowhead Pharmaceuticals, Inc. Common 04280A100 2,134 74,186 SH   SOLE   74,186 0 0
Ascendis Pharma A/S Sponsored ADR 04351P101 7,807 69,332 SH   SOLE   69,332 0 0
AstraZeneca PLC Sponsored ADR 046353108 12,331 276,098 SH   SOLE   276,098 0 0
Atreca, Inc. Class A Common 04965G109 5,833 352,424 SH   SOLE   352,424 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 1,317 90,788 SH   SOLE   90,788 0 0
Avadel Pharmaceuticals plc Sponsored ADR 05337M104 4,495 566,066 SH   SOLE   566,066 0 0
AVROBIO, Inc. Common 05455M100 1,165 74,874 SH   SOLE   74,874 0 0
Axonics Modulation Technologies, Inc. Common 05465P101 714 28,100 SH   SOLE   28,100 0 0
Axsome Therapeutics, Inc. Common 05464T104 1,858 31,591 SH   SOLE   31,591 0 0
Bausch Health Companies Inc. Common 071734107 1,835 118,412 SH   SOLE   118,412 0 0
Baxter International Inc. Common 071813109 7,890 97,183 SH   SOLE   97,183 0 0
Becton, Dickinson and Company Common 075887109 17,866 77,754 SH   SOLE   77,754 0 0
BeiGene, Ltd. Sponsored ADR 07725L102 9,231 74,984 SH   SOLE   74,984 0 0
Bellicum Pharmaceuticals, Inc. Common 079481404 28 6,000 SH   SOLE   6,000 0 0
Bio-Techne Corporation Common 09073M104 10,939 57,691 SH   SOLE   57,691 0 0
Biogen Inc. Common 09062X103 105,271 332,735 SH   SOLE   332,735 0 0
Biohaven Pharmaceutical Holding Company Ltd. Common G11196105 1,537 45,164 SH   SOLE   45,164 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 22,867 270,613 SH   SOLE   270,613 0 0
bluebird bio, Inc. Common 09609G100 3,870 84,194 SH   SOLE   84,194 0 0
Blueprint Medicines Corporation Common 09627Y109 8,148 139,336 SH   SOLE   139,336 0 0
Boston Scientific Corporation Common 101137107 19,175 587,662 SH   SOLE   587,662 0 0
BridgeBio Pharma, Inc. Common 10806X102 1,138 39,228 SH   SOLE   39,228 0 0
Bristol-Myers Squibb Company Common 110122108 47,097 844,932 SH   SOLE   844,932 0 0
Bristol-Myers Squibb Company Right 110122157 5,600 1,473,710 SH   SOLE   1,473,710 0 0
Celldex Therapeutics, Inc. Common 15117B202 12 7,053 SH   SOLE   7,053 0 0
Cellectis Sponsored ADR 15117K103 1,013 110,147 SH   SOLE   110,147 0 0
Centene Corporation Common 15135B101 17,122 288,194 SH   SOLE   288,194 0 0
Cerner Corporation Common 156782104 5,134 81,500 SH   SOLE   81,500 0 0
Charles River Laboratories International, Inc. Common 159864107 2,331 18,467 SH   SOLE   18,467 0 0
Cidara Therapeutics, Inc. Common 171757107 484 195,256 SH   SOLE   195,256 0 0
Cigna Corporation Common 125523100 25,276 142,655 SH   SOLE   142,655 0 0
Clearside Biomedical, Inc. Common 185063104 281 165,330 SH   SOLE   165,330 0 0
Coherus Biosciences, Inc. Common 19249H103 1,811 111,663 SH   SOLE   111,663 0 0
Community Health Systems, Inc. Common 203668108 393 117,735 SH   SOLE   117,735 0 0
Community Healthcare Trust Incorporated Common 20369C106 570 14,900 SH   SOLE   14,900 0 0
CRISPR Therapeutics AG Namen AKT H17182108 3,233 76,222 SH   SOLE   76,222 0 0
CVS Health Corporation Common 126650100 29,546 497,986 SH   SOLE   497,986 0 0
CymaBay Therapeutics, Inc. Common 23257D103 130 88,102 SH   SOLE   88,102 0 0
Danaher Corporation Common 235851102 22,056 159,352 SH   SOLE   159,352 0 0
Deciphera Pharmaceuticals, Inc. Common 24344T101 2,527 61,370 SH   SOLE   61,370 0 0
DENTSPLY SIRONA Inc. Common 24906P109 4,455 114,736 SH   SOLE   114,736 0 0
Diversified Healthcare Trust Common 25525P107 1,299 357,720 SH   SOLE   357,720 0 0
Editas Medicine, Inc. Common 28106W103 2,582 130,201 SH   SOLE   130,201 0 0
Edwards Lifesciences Corporation Common 28176E108 12,710 67,382 SH   SOLE   67,382 0 0
Eidos Therapeutics, Inc. Common 28249H104 980 20,000 SH   SOLE   20,000 0 0
Eli Lilly and Company Common 532457108 35,883 258,669 SH   SOLE   258,669 0 0
Endo International plc Shares G30401106 1,967 531,570 SH   SOLE   531,570 0 0
Epizyme, Inc. Common 29428V104 3,222 207,752 SH   SOLE   207,752 0 0
Esperion Therapeutics, Inc. Common 29664W105 1,311 41,577 SH   SOLE   41,577 0 0
Evolent Health, Inc. Common 30050B101 1,254 231,027 SH   SOLE   231,027 0 0
Exact Sciences Corporation Common 30063P105 1,342 23,133 SH   SOLE   23,133 0 0
Exelixis, Inc. Common 30161Q104 8,870 515,125 SH   SOLE   515,125 0 0
Fate Therapeutics, Inc. Common 31189P102 3,680 165,672 SH   SOLE   165,672 0 0
FibroGen, Inc. Common 31572Q808 6,751 194,270 SH   SOLE   194,270 0 0
Five Star Senior Living Inc. Common 33832D205 67 24,237 SH   SOLE   24,237 0 0
Galapagos NV Sponsored ADR 36315X101 1,282 6,543 SH   SOLE   6,543 0 0
Galera Therapeutics, Inc. Common 36338D108 3,958 416,666 SH   SOLE   416,666 0 0
Genmab A/S Sponsored ADS 372303206 3,139 148,148 SH   SOLE   148,148 0 0
Gilead Sciences, Inc. Common 375558103 141,170 1,888,305 SH   SOLE   1,888,305 0 0
GlaxoSmithKline PLC Shares 37733W105 7,838 206,868 SH   SOLE   206,868 0 0
Global Blood Therapeutics, Inc. Common 37890U108 6,033 118,083 SH   SOLE   118,083 0 0
Global Medical REIT Inc. Common 37954A204 1,770 174,897 SH   SOLE   174,897 0 0
Grifols, S.A. Sponsored ADR 398438408 954 47,373 SH   SOLE   47,373 0 0
Guardant Health, Inc. Common 40131M109 1,646 23,656 SH   SOLE   23,656 0 0
GW Pharmaceuticals plc ADS 36197T103 4,387 50,101 SH   SOLE   50,101 0 0
Halozyme Therapeutics, Inc. Common 40637H109 1,258 69,917 SH   SOLE   69,917 0 0
HCA Healthcare, Inc. Common 40412C101 7,532 83,833 SH   SOLE   83,833 0 0
Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 891 10,055 SH   SOLE   10,055 0 0
Healthcare Realty Trust Incorporated Common 421946104 2,905 104,024 SH   SOLE   104,024 0 0
Healthcare Trust of America, Inc. Common 42225P501 1,716 70,662 SH   SOLE   70,662 0 0
HealthEquity, Inc. Common 42226A107 1,382 27,310 SH   SOLE   27,310 0 0
Healthpeak Properties, Inc. Common 42250P103 3,587 150,392 SH   SOLE   150,392 0 0
Heron Therapeutics, Inc. Common 427746102 1,540 131,183 SH   SOLE   131,183 0 0
Hologic, Inc. Common 436440101 1,143 32,564 SH   SOLE   32,564 0 0
Horizon Therapeutics plc Shares G46188101 11,826 399,257 SH   SOLE   399,257 0 0
Humana Inc. Common 444859102 14,486 46,130 SH   SOLE   46,130 0 0
IDEXX Laboratories, Inc. Common 45168D104 9,766 40,314 SH   SOLE   40,314 0 0
Illumina, Inc. Common 452327109 72,464 265,319 SH   SOLE   265,319 0 0
ImmunoGen, Inc. Common 45253H101 574 168,190 SH   SOLE   168,190 0 0
Immunomedics, Inc. Common 452907108 6,566 487,103 SH   SOLE   487,103 0 0
Incyte Corporation Common 45337C102 31,653 432,246 SH   SOLE   432,246 0 0
Inogen, Inc. Common 45780L104 2,656 51,406 SH   SOLE   51,406 0 0
Insmed Incorporated Common 457669307 1,577 98,387 SH   SOLE   98,387 0 0
Intellia Therapeutics, Inc. Common 45826J105 673 55,050 SH   SOLE   55,050 0 0
Intercept Pharmaceuticals, Inc. Common 45845P108 2,167 34,414 SH   SOLE   34,414 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 1,448 94,238 SH   SOLE   94,238 0 0
Intuitive Surgical, Inc. Common 46120E602 16,856 34,039 SH   SOLE   34,039 0 0
Ionis Pharmaceuticals, Inc. Common 462222100 9,135 193,201 SH   SOLE   193,201 0 0
Iovance Biotherapeutics, Inc. Common 462260100 6,618 221,073 SH   SOLE   221,073 0 0
IQVIA Holdings Inc. Common 46266C105 8,873 82,266 SH   SOLE   82,266 0 0
Jazz Pharmaceuticals plc Shares G50871105 6,728 67,456 SH   SOLE   67,456 0 0
Johnson & Johnson Common 478160104 109,988 838,769 SH   SOLE   838,769 0 0
Kodiak Sciences Inc. Common 50015M109 1,104 23,153 SH   SOLE   23,153 0 0
Koninklijke Philips N.V. NY Reg Sh 500472303 2,241 55,796 SH   SOLE   55,796 0 0
Laboratory Corporation of America Holdings Sponsored ADR 50540R409 3,972 31,424 SH   SOLE   31,424 0 0
Ligand Pharmaceuticals Incorporated Common 53220K504 2,225 30,590 SH   SOLE   30,590 0 0
LTC Properties, Inc. Common 502175102 5,633 182,293 SH   SOLE   182,293 0 0
Madrigal Pharmaceuticals, Inc. Common 558868105 891 13,340 SH   SOLE   13,340 0 0
Magenta Therapeutics, Inc. Common 55910K108 105 16,757 SH   SOLE   16,757 0 0
Mallinckrodt plc Sponsored ADR G5785G107 65 32,980 SH   SOLE   32,980 0 0
McKesson Corporation Common 58155Q103 8,051 59,525 SH   SOLE   59,525 0 0
Medical Properties Trust, Inc. Common 58463J304 7,119 411,743 SH   SOLE   411,743 0 0
Medpace Holdings, Inc. Common 58506Q109 1,385 18,871 SH   SOLE   18,871 0 0
Medtronic plc Shares G5960L103 40,311 447,011 SH   SOLE   447,011 0 0
Menlo Therapeutics Inc. Common 586858102 478 178,181 SH   SOLE   178,181 0 0
Merck & Co., Inc. Common 58933Y105 78,679 1,022,596 SH   SOLE   1,022,596 0 0
Merus N.V. Common N5749R100 257 21,215 SH   SOLE   21,215 0 0
Mettler-Toledo International Inc. Common 592688105 4,228 6,123 SH   SOLE   6,123 0 0
Milestone Pharmaceuticals Inc. Common 59935V107 392 213,310 SH   SOLE   213,310 0 0
Mirati Therapeutics, Inc. Common 60468T105 6,056 78,784 SH   SOLE   78,784 0 0
Moderna, Inc. Common 60770K107 7,612 254,146 SH   SOLE   254,146 0 0
Molecular Templates, Inc. Common 608550109 562 42,313 SH   SOLE   42,313 0 0
Momenta Pharmaceuticals, Inc. Common 60877T100 2,484 91,316 SH   SOLE   91,316 0 0
MorphoSys AG Sponsored ADS 617760202 476 19,390 SH   SOLE   19,390 0 0
Mylan N.V. Shares N59465109 15,070 1,010,754 SH   SOLE   1,010,754 0 0
MyoKardia, Inc. Common 62857M105 905 19,300 SH   SOLE   19,300 0 0
National Health Investors, Inc. Common 63633D104 497 10,038 SH   SOLE   10,038 0 0
Nektar Therapeutics Common 640268108 4,696 263,079 SH   SOLE   263,079 0 0
Neurocrine Biosciences, Inc. Common 64125C109 17,842 206,150 SH   SOLE   206,150 0 0
New Senior Investment Group Inc. Common 648691103 656 256,398 SH   SOLE   256,398 0 0
Novartis AG Sponsored ADR 66987V109 14,828 179,847 SH   SOLE   179,847 0 0
Novavax, Inc. Common 670002401 388 28,550 SH   SOLE   28,550 0 0
Novo Nordisk A/S Sponsored ADR 670100205 8,067 134,005 SH   SOLE   134,005 0 0
NovoCure Ltd. Ordinary Shares G6674U108 7,235 107,438 SH   SOLE   107,438 0 0
Omega Healthcare Investors, Inc. Common 681936100 8,133 306,433 SH   SOLE   306,433 0 0
Ovid Therapeutics Inc. Sponsored ADR 690469101 1,111 372,733 SH   SOLE   372,733 0 0
Pacific Biosciences of California, Inc. Common 69404D108 1,516 495,495 SH   SOLE   495,495 0 0
PerkinElmer, Inc. Common 714046109 2,898 38,494 SH   SOLE   38,494 0 0
Perrigo Company plc Shares G97822103 520 10,818 SH   SOLE   10,818 0 0
Pfizer Inc. Common 717081103 59,413 1,820,248 SH   SOLE   1,820,248 0 0
Physicians Realty Trust Common 71943U104 6,911 495,733 SH   SOLE   495,733 0 0
Pieris Pharmaceuticals, Inc. Common 720795103 3,304 1,449,269 SH   SOLE   1,449,269 0 0
Portola Pharmaceuticals, Inc. Sponsored ADR 737010108 779 109,246 SH   SOLE   109,246 0 0
PRA Health Sciences, Inc. Common 69354M108 11,917 143,508 SH   SOLE   143,508 0 0
PTC Therapeutics, Inc. Common 69366J200 5,390 120,827 SH   SOLE   120,827 0 0
Puma Biotechnology, Inc. Common 74587V107 602 71,340 SH   SOLE   71,340 0 0
Quest Diagnostics Incorporated Common 74834L100 1,688 21,025 SH   SOLE   21,025 0 0
Quorum Health Corporation Common 74909E106 11 23,725 SH   SOLE   23,725 0 0
Quotient Ltd. Common G73268107 1,027 260,030 SH   SOLE   260,030 0 0
Ra Pharmaceuticals, Inc. Common 74933V108 1,716 35,743 SH   SOLE   35,743 0 0
Reata Pharmaceuticals, Inc. Class A 75615P103 5,071 35,129 SH   SOLE   35,129 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 83,438 170,878 SH   SOLE   170,878 0 0
REGENXBIO Inc. Common 75901B107 703 21,700 SH   SOLE   21,700 0 0
ResMed Inc. Common 761152107 2,626 17,831 SH   SOLE   17,831 0 0
Revance Therapeutics, Inc. Common 761330109 1,270 85,840 SH   SOLE   85,840 0 0
Rocket Pharmaceuticals, Inc. Common 77313F106 2,895 207,555 SH   SOLE   207,555 0 0
Rubius Therapeutics, Inc. Common 78116T103 694 155,982 SH   SOLE   155,982 0 0
Sabra Health Care REIT, Inc. Common 78573L106 5,576 510,660 SH   SOLE   510,660 0 0
Sage Therapeutics Inc Common 78667J108 2,763 96,211 SH   SOLE   96,211 0 0
Sangamo Therapeutics, Inc. Common 800677106 954 149,835 SH   SOLE   149,835 0 0
Sanofi Sponsored ADR 80105N105 14,312 327,367 SH   SOLE   327,367 0 0
Sarepta Therapeutics, Inc. Common 803607100 13,707 140,129 SH   SOLE   140,129 0 0
Seattle Genetics, Inc. Common 812578102 24,752 214,530 SH   SOLE   214,530 0 0
Smith & Nephew plc Shares 83175M205 3,571 99,560 SH   SOLE   99,560 0 0
Spectrum Pharmaceuticals, Inc. Common 84763A108 267 114,670 SH   SOLE   114,670 0 0
STERIS plc Shares G8473T100 1,570 11,218 SH   SOLE   11,218 0 0
Stryker Corporation Common 863667101 22,609 135,795 SH   SOLE   135,795 0 0
Sutro Biopharma, Inc. Common 869367102 6,541 641,268 SH   SOLE   641,268 0 0
Syneos Health, Inc. Class A 87166B102 4,257 108,001 SH   SOLE   108,001 0 0
Takeda Pharmaceutical Company Ltd. Sponsored ADS 874060205 3,190 210,146 SH   SOLE   210,146 0 0
Teleflex Incorporated Common 879369106 5,052 17,252 SH   SOLE   17,252 0 0
Tenet Healthcare Corporation Common 88033G407 1,393 96,736 SH   SOLE   96,736 0 0
Tetraphase Pharmaceuticals, Inc. Common 88165N204 55 42,965 SH   SOLE   42,965 0 0
Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 7,057 785,851 SH   SOLE   785,851 0 0
Theravance Biopharma, Inc. Common G8807B106 5,288 228,836 SH   SOLE   228,836 0 0
Thermo Fisher Scientific Inc. Common 883556102 31,770 112,025 SH   SOLE   112,025 0 0
Trillium Therapeutics Inc. Common 89620X506 1,810 448,049 SH   SOLE   448,049 0 0
Turning Point Therapeutics, Inc. Common 90041T108 254 5,677 SH   SOLE   5,677 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108 4,331 97,480 SH   SOLE   97,480 0 0
uniQure N.V. Shares N90064101 2,081 43,849 SH   SOLE   43,849 0 0
United Therapeutics Corporation Class B 91307C102 6,023 63,513 SH   SOLE   63,513 0 0
Unitedhealth Group Incorporated Common 91324P102 56,566 226,827 SH   SOLE   226,827 0 0
Universal Health Realty Income Trust Shares 91359E105 1,135 11,258 SH   SOLE   11,258 0 0
Ventas, Inc. Common 92276F100 5,577 208,108 SH   SOLE   208,108 0 0
Verona Pharma plc Sponsored ADR 925050106 1,043 253,179 SH   SOLE   253,179 0 0
Vertex Pharmaceuticals Incorporated Common 92532F100 115,579 485,730 SH   SOLE   485,730 0 0
Viela Bio, Inc. Common 926613100 19 500 SH   SOLE   500 0 0
Waters Corporation Common 941848103 4,733 26,000 SH   SOLE   26,000 0 0
WaVe Life Sciences Ltd. Shares Y95308105 1,201 128,146 SH   SOLE   128,146 0 0
Welltower Inc. Common 95040Q104 9,297 203,083 SH   SOLE   203,083 0 0
Xencor, Inc. Common 98401F105 4,429 148,231 SH   SOLE   148,231 0 0
Y-mAbs Therapeutics, Inc. Common 984241109 1,998 76,548 SH   SOLE   76,548 0 0
Zai Lab Ltd. ADR 98887Q104 1,932 37,523 SH   SOLE   37,523 0 0
Zimmer Biomet Holdings, Inc. Common 98956P102 7,901 78,168 SH   SOLE   78,168 0 0
Zoetis Inc. Class A 98978V103 17,883 151,952 SH   SOLE   151,952 0 0
Zogenix, Inc. Common 98978L204 5,327 215,406 SH   SOLE   215,406 0 0
Zymeworks Inc. Common 98985W102 539 15,192 SH   SOLE   15,192 0 0