The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 72,978 502,745 SH   SOLE 0 502,745 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 68,932 1,631,524 SH   SOLE 0 1,631,524 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 47,524 3,295,712 SH   SOLE 0 3,295,712 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 182 73,500 SH   SOLE 0 73,500 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 57,689 642,491 SH   SOLE 0 642,491 0 0
ALIGN TECHNOLOGY INC COM 016255101 13,256 76,205 SH   SOLE 0 76,205 0 0
ALIMERA SCIENCES INC COM 016259103 804 200,919 SH   SOLE 0 200,919 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 18,557 3,002,748 SH   SOLE 0 3,002,748 0 0
AMICUS THERAPEUTICS INC COM 03152W109 68,816 7,447,618 SH   SOLE 0 7,447,618 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 130,482 1,544,163 SH   SOLE 0 1,544,163 0 0
CLOVIS ONCOLOGY INC COM 189464100 29,484 4,635,789 SH   SOLE 0 4,635,789 0 0
CYTOKINETICS INC COM 23282W605 1,458 123,686 SH   SOLE 0 123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 6,095 331,813 SH   SOLE 0 331,813 0 0
EPIZYME INC COM 29428V104 86,108 5,551,803 SH   SOLE 0 5,551,803 0 0
IDERA PHARMACEUTICALS INC COM 45168K405 102 77,044 SH   SOLE 0 77,044 0 0
IMMUNOMEDICS INC COM 452907108 71,319 5,290,746 SH   SOLE 0 5,290,746 0 0
INSMED INC COM 457669307 97,072 6,055,623 SH   SOLE 0 6,055,623 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101 575 37,400 SH   SOLE 0 37,400 0 0
KALEIDO BIOSCIENCES INC COM 483347100 4,846 787,999 SH   SOLE 0 787,999 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 82,601 4,299,901 SH   SOLE 0 4,299,901 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 254 125,321 SH   SOLE 0 125,321 0 0
MINERVA NEUROSCIENCES INC COM 603380106 219 36,319 SH   SOLE 0 36,319 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 41,560 1,527,956 SH   SOLE 0 1,527,956 0 0
PROTHENA CORP PLC COM G72800108 8,296 775,296 SH   SOLE 0 775,296 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 11,784 1,396,163 SH   SOLE 0 1,396,163 0 0
RETROPHIN INC COM 761299106 686 47,000 SH   SOLE 0 47,000 0 0
REVANCE THERAPEUTICS INC COM 761330109 9,112 615,705 SH   SOLE 0 615,705 0 0
RIGEL PHARMACEUTICALS INC COM 766559603 5,526 3,542,551 SH   SOLE 0 3,542,551 0 0
SAGE THERAPEUTICS INC COM 78667J108 16,849 586,674 SH   SOLE 0 586,674 0 0
STAAR SURGICAL CO COM 852312305 105,765 3,278,523 SH   SOLE 0 3,278,523 0 0
SUNESIS PHARMACEUTICALS INC COM 867328700 482 1,162,473 SH   SOLE 0 1,162,473 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 725 66,100 SH   SOLE 0 66,100 0 0
UNITED THERAPEUTICS CORP COM 91307C102 83,121 876,575 SH   SOLE 0 876,575 0 0
UROGEN PHARMA LTD COM M96088105 437 24,500 SH   SOLE 0 24,500 0 0
VANDA PHARMACEUTICALS INC COM 921659108 42,837 4,134,846 SH   SOLE 0 4,134,846 0 0
WRIGHT MEDICAL GROUP NV COM N96617118 6,960 242,940 SH   SOLE 0 242,940 0 0
ZOGENIX INC COM 98978L204 730 29,500 SH   SOLE 0 29,500 0 0