The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
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UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ABIOMED INC | COM | 003654100 | 54,580 | 376,000 | SH | DFND | 1 | 376,000 | 0 | 0 | |
| ACCELERON PHARMA INC | COM | 00434H108 | 30,825 | 343,000 | SH | DFND | 1 | 343,000 | 0 | 0 | |
| ADAPTHEALTH CORP | COM CL A | 00653Q102 | 275,198 | 17,199,888 | SH | DFND | 1 | 17,199,888 | 0 | 0 | |
| ADVERUM BIOTECHNOLOGIES INC | COM | 00773U108 | 20,273 | 2,075,000 | SH | DFND | 1 | 2,075,000 | 0 | 0 | |
| AERIE PHARMACEUTICALS INC | COM | 00771V108 | 34,184 | 2,532,147 | SH | DFND | 1 | 2,532,147 | 0 | 0 | |
| ALECTOR INC | COM | 014442107 | 41,962 | 1,738,997 | SH | DFND | 1 | 1,738,997 | 0 | 0 | |
| AMICUS THERAPEUTICS INC | COM | 03152W109 | 30,067 | 3,253,960 | SH | DFND | 1 | 3,253,960 | 0 | 0 | |
| APPLIED THERAPEUTICS INC | COM | 03828A101 | 9,100 | 278,359 | SH | DFND | 1 | 278,359 | 0 | 0 | |
| ARDELYX INC | COM | 039697107 | 17,527 | 3,083,000 | SH | DFND | 1 | 3,083,000 | 0 | 0 | |
| ARGENX SE | SPONSORED ADR | 04016X101 | 19,994 | 151,779 | SH | DFND | 1 | 151,779 | 0 | 0 | |
| ARTARA THERAPEUTICS INC | COM | 04300J107 | 9,951 | 432,670 | SH | DFND | 1 | 432,670 | 0 | 0 | |
| ARVINAS INC | COM | 04335A105 | 48,881 | 1,212,922 | SH | DFND | 1 | 1,212,922 | 0 | 0 | |
| AVROBIO INC | COM | 05455M100 | 17,503 | 1,124,879 | SH | DFND | 1 | 1,124,879 | 0 | 0 | |
| AXOGEN INC | COM | 05463X106 | 9,755 | 937,983 | SH | DFND | 1 | 937,983 | 0 | 0 | |
| AXONICS MODULATION TECHNOLOG | COM | 05465P101 | 45,601 | 1,794,594 | SH | DFND | 1 | 1,794,594 | 0 | 0 | |
| BIOCRYST PHARMACEUTICALS INC | COM | 09058V103 | 9,306 | 4,652,926 | SH | DFND | 1 | 4,652,926 | 0 | 0 | |
| BIODELIVERY SCIENCES INTL IN | COM | 09060J106 | 23,438 | 6,184,243 | SH | DFND | 1 | 6,184,243 | 0 | 0 | |
| BLACK DIAMOND THERAPEUTICS I | COM | 09203E105 | 13,373 | 536,001 | SH | DFND | 1 | 536,001 | 0 | 0 | |
| BLUEPRINT MEDICINES CORP | COM | 09627Y109 | 26,782 | 457,968 | SH | DFND | 1 | 457,968 | 0 | 0 | |
| BROOKDALE SR LIVING INC | COM | 112463104 | 57,415 | 18,402,355 | SH | DFND | 1 | 18,402,355 | 0 | 0 | |
| CABALETTA BIO INC | COM | 12674W109 | 9,375 | 1,284,313 | SH | DFND | 1 | 1,284,313 | 0 | 0 | |
| CENTENE CORP DEL | COM | 15135B101 | 75,285 | 1,267,206 | SH | DFND | 1 | 1,267,206 | 0 | 0 | |
| CERUS CORP | COM | 157085101 | 10,252 | 2,204,700 | SH | DFND | 1 | 2,204,700 | 0 | 0 | |
| CHANGE HEALTHCARE INC | COM | 15912K100 | 2,146 | 214,789 | SH | DFND | 1 | 214,789 | 0 | 0 | |
| CLOVIS ONCOLOGY INC | NOTE 2.500% 9/1 | 189464AB6 | 43,581 | 49,064,000 | PRN | DFND | 1 | 49,064,000 | 0 | 0 | |
| CONSTELLATION PHARMCETICLS I | COM | 210373106 | 29,987 | 954,100 | SH | DFND | 1 | 954,100 | 0 | 0 | |
| DBV TECHNOLOGIES S A | SPONSORED ADR | 23306J101 | 20,422 | 5,209,692 | SH | DFND | 1 | 5,209,692 | 0 | 0 | |
| DECIPHERA PHARMACEUTICALS IN | COM | 24344T101 | 24,269 | 589,485 | SH | DFND | 1 | 589,485 | 0 | 0 | |
| DEXCOM INC | NOTE 0.750%12/0 | 252131AH0 | 58,922 | 34,000,000 | PRN | DFND | 1 | 34,000,000 | 0 | 0 | |
| DEXCOM INC | COM | 252131107 | 23,426 | 87,000 | SH | DFND | 1 | 87,000 | 0 | 0 | |
| DFP HEALTHCARE ACQUISITNS CO | UNIT 03/31/2025 | 23343Q209 | 103,031 | 10,460,000 | SH | DFND | 1 | 10,460,000 | 0 | 0 | |
| EDITAS MEDICINE INC | COM | 28106W103 | 22,980 | 1,158,841 | SH | DFND | 1 | 1,158,841 | 0 | 0 | |
| ENDOLOGIX INC | COM NEW | 29266S304 | 656 | 950,000 | SH | DFND | 1 | 950,000 | 0 | 0 | |
| FATE THERAPEUTICS INC | COM | 31189P102 | 35,913 | 1,616,993 | SH | DFND | 1 | 1,616,993 | 0 | 0 | |
| FORTY SEVEN INC | COM | 34983P104 | 14,826 | 155,380 | SH | DFND | 1 | 155,380 | 0 | 0 | |
| FREQUENCY THERAPEUTICS INC | COM | 35803L108 | 16,843 | 945,718 | SH | DFND | 1 | 945,718 | 0 | 0 | |
| GLAUKOS CORP | COM | 377322102 | 15,985 | 517,982 | SH | DFND | 1 | 517,982 | 0 | 0 | |
| HARPOON THERAPEUTICS INC | COM | 41358P106 | 1,941 | 167,637 | SH | DFND | 1 | 167,637 | 0 | 0 | |
| HOMOLOGY MEDICINES INC | COM | 438083107 | 62,740 | 4,037,305 | SH | DFND | 1 | 4,037,305 | 0 | 0 | |
| HORIZON PHARMA INVT LTD | NOTE 2.500% 3/1 | 44052TAB7 | 168,706 | 144,832,000 | PRN | DFND | 1 | 144,832,000 | 0 | 0 | |
| HORIZON THERAPEUTICS PUB LTD | SHS | G46188101 | 174,418 | 5,888,511 | SH | DFND | 1 | 5,888,511 | 0 | 0 | |
| IMARA INC | COM | 45249V107 | 8,015 | 500,000 | SH | DFND | 1 | 500,000 | 0 | 0 | |
| IMMUNOMEDICS INC | COM | 452907108 | 55,369 | 4,107,464 | SH | DFND | 1 | 4,107,464 | 0 | 0 | |
| INSMED INC | NOTE 1.750% 1/1 | 457669AA7 | 50,928 | 61,000,000 | PRN | DFND | 1 | 61,000,000 | 0 | 0 | |
| INTERCEPT PHARMACEUTICALS IN | NOTE 3.250% 7/0 | 45845PAA6 | 46,815 | 57,791,000 | PRN | DFND | 1 | 57,791,000 | 0 | 0 | |
| INTERCEPT PHARMACEUTICALS IN | NOTE 2.000% 5/1 | 45845PAB4 | 2,960 | 3,500,000 | PRN | DFND | 1 | 3,500,000 | 0 | 0 | |
| INTERSECT ENT INC | COM | 46071F103 | 32,685 | 2,758,267 | SH | DFND | 1 | 2,758,267 | 0 | 0 | |
| ITAMAR MED LTD | SPONSORED ADS | 465437101 | 5,880 | 499,136 | SH | DFND | 1 | 499,136 | 0 | 0 | |
| IVERIC BIO INC | COM | 46583P102 | 7,800 | 2,267,409 | SH | DFND | 1 | 2,267,409 | 0 | 0 | |
| JAZZ INVESTMENTS I LTD | NOTE 1.875% 8/1 | 472145AB7 | 19,214 | 20,000,000 | PRN | DFND | 1 | 20,000,000 | 0 | 0 | |
| KEMPHARM INC | COM | 488445107 | 94 | 418,613 | SH | DFND | 1 | 418,613 | 0 | 0 | |
| LUMOS PHARMA INC | COM | 55028X109 | 7,957 | 936,169 | SH | DFND | 1 | 936,169 | 0 | 0 | |
| MALLINCKRODT PUB LTD CO | SHS | G5785G107 | 7,973 | 4,026,750 | SH | DFND | 1 | 4,026,750 | 0 | 0 | |
| MCKESSON CORP | COM | 58155Q103 | 23,730 | 175,437 | SH | DFND | 1 | 175,437 | 0 | 0 | |
| MILLENDO THERAPEUTICS INC | COM | 60040X103 | 892 | 168,871 | SH | DFND | 1 | 168,871 | 0 | 0 | |
| MIRATI THERAPEUTICS INC | COM | 60468T105 | 18,618 | 242,200 | SH | DFND | 1 | 242,200 | 0 | 0 | |
| MIRUM PHARMACEUTICALS INC | COM | 604749101 | 48,285 | 3,448,912 | SH | DFND | 1 | 3,448,912 | 0 | 0 | |
| MOLINA HEALTHCARE INC | COM | 60855R100 | 23,052 | 165,000 | SH | DFND | 1 | 165,000 | 0 | 0 | |
| MYLAN N V | SHS EURO | N59465109 | 181,177 | 12,151,362 | SH | DFND | 1 | 12,151,362 | 0 | 0 | |
| MYOKARDIA INC | COM | 62857M105 | 16,240 | 346,409 | SH | DFND | 1 | 346,409 | 0 | 0 | |
| NATERA INC | COM | 632307104 | 39,296 | 1,316,000 | SH | DFND | 1 | 1,316,000 | 0 | 0 | |
| NEOS THERAPEUTICS INC | COM | 64052L106 | 241 | 320,993 | SH | DFND | 1 | 320,993 | 0 | 0 | |
| NEURONETICS INC | COM | 64131A105 | 2,977 | 1,575,000 | SH | DFND | 1 | 1,575,000 | 0 | 0 | |
| NEVRO CORP | NOTE 1.750% 6/0 | 64157FAA1 | 133,920 | 115,776,000 | PRN | DFND | 1 | 115,776,000 | 0 | 0 | |
| NUVASIVE INC | NOTE 2.250% 3/1 | 670704AG0 | 88,732 | 85,000,000 | PRN | DFND | 1 | 85,000,000 | 0 | 0 | |
| ORCHARD THERAPEUTICS PLC | ADS | 68570P101 | 66,733 | 8,862,247 | SH | DFND | 1 | 8,862,247 | 0 | 0 | |
| OXFORD IMMUNOTEC GLOBAL PLC | ORD SHS | G6855A103 | 1,430 | 154,396 | SH | DFND | 1 | 154,396 | 0 | 0 | |
| PACIRA BIOSCIENCES | COM | 695127100 | 54,571 | 1,627,521 | SH | DFND | 1 | 1,627,521 | 0 | 0 | |
| PACIRA BIOSCIENCES | NOTE 2.375% 4/0 | 695127AD2 | 19,100 | 20,000,000 | SH | DFND | 1 | 20,000,000 | 0 | 0 | |
| PASSAGE BIO INC | COM | 702712100 | 10,558 | 670,367 | SH | DFND | 1 | 670,367 | 0 | 0 | |
| PTC THERAPEUTICS INC | NOTE 3.000% 8/1 | 69366JAB7 | 26,850 | 24,877,000 | PRN | DFND | 1 | 24,877,000 | 0 | 0 | |
| PUMA BIOTECHNOLOGY INC | COM | 74587V107 | 8,130 | 963,212 | SH | DFND | 1 | 963,212 | 0 | 0 | |
| REATA PHARMACEUTICALS INC | CL A | 75615P103 | 26,539 | 183,865 | SH | DFND | 1 | 183,865 | 0 | 0 | |
| REVOLUTION MEDICINES INC | COM | 76155X100 | 39,359 | 1,796,383 | SH | DFND | 1 | 1,796,383 | 0 | 0 | |
| RHYTHM PHARMACEUTICALS INC | COM | 76243J105 | 46,140 | 3,031,565 | SH | DFND | 1 | 3,031,565 | 0 | 0 | |
| ROCKET PHARMACEUTICALS INC | COM | 77313F106 | 23,399 | 1,677,367 | SH | DFND | 1 | 1,677,367 | 0 | 0 | |
| SAREPTA THERAPEUTICS INC | COM | 803607100 | 22,988 | 235,000 | SH | DFND | 1 | 235,000 | 0 | 0 | |
| SCHRODINGER INC | COM | 80810D103 | 58,047 | 1,346,167 | SH | DFND | 1 | 1,346,167 | 0 | 0 | |
| SELECT MED HLDGS CORP | COM | 81619Q105 | 15,945 | 1,063,000 | SH | DFND | 1 | 1,063,000 | 0 | 0 | |
| SIENTRA INC | COM | 82621J105 | 8,413 | 4,227,680 | SH | DFND | 1 | 4,227,680 | 0 | 0 | |
| SILK RD MED INC | COM | 82710M100 | 42,435 | 1,348,000 | SH | DFND | 1 | 1,348,000 | 0 | 0 | |
| SPRINGWORKS THERAPEUTICS INC | COM | 85205L107 | 21,283 | 788,243 | SH | DFND | 1 | 788,243 | 0 | 0 | |
| SYNLOGIC INC | COM | 87166L100 | 654 | 380,300 | SH | DFND | 1 | 380,300 | 0 | 0 | |
| SYROS PHARMACEUTICALS INC | COM | 87184Q107 | 7,525 | 1,268,946 | SH | DFND | 1 | 1,268,946 | 0 | 0 | |
| TANDEM DIABETES CARE INC | COM NEW | 875372203 | 26,568 | 412,867 | SH | DFND | 1 | 412,867 | 0 | 0 | |
| TURNING POINT THERAPEUTICS I | COM | 90041T108 | 18,459 | 413,321 | SH | DFND | 1 | 413,321 | 0 | 0 | |
| UNIVERSAL HLTH SVCS INC | CL B | 913903100 | 13,760 | 138,874 | SH | DFND | 1 | 138,874 | 0 | 0 | |
| VAPOTHERM INC | COM | 922107107 | 10,483 | 556,725 | SH | DFND | 1 | 556,725 | 0 | 0 | |
| VERICEL CORP | COM | 92346J108 | 40,780 | 4,447,109 | SH | DFND | 1 | 4,447,109 | 0 | 0 | |
| XERIS PHARMACEUTICALS INC | COM | 98422L107 | 6,695 | 3,433,291 | SH | DFND | 1 | 3,433,291 | 0 | 0 | |