The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
3M CO COM 88579Y101 1,913 12,262 SH   SOLE   12,262 0 0
ABBOTT LABS COM 002824100 2,194 24,001 SH   SOLE   24,001 0 0
ABBVIE INC COM 00287Y109 3,845 39,162 SH   SOLE   39,162 0 0
ABERDEEN STD GOLD ETF TR PHYSCL GOLD SHS 00326A104 424 24,740 SH   SOLE   24,740 0 0
ABIOMED INC COM 003654100 11,401 47,198 SH   SOLE   47,198 0 0
ACCELERATE DIAGNOSTICS INC COM 00430H102 11,453 755,483 SH   SOLE   755,483 0 0
ACCENTURE PLC IRELAND SHS CLASS A G1151C101 746 3,475 SH   SOLE   3,475 0 0
ADOBE INC COM 00724F101 3,213 7,381 SH   SOLE   7,381 0 0
AIR PRODS & CHEMS INC COM 009158106 679 2,810 SH   SOLE   2,810 0 0
ALBIREO PHARMA INC COM 01345P106 13,304 502,212 SH   SOLE   502,212 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 382 1,769 SH   SOLE   1,769 0 0
ALIGN TECHNOLOGY INC COM 016255101 716 2,609 SH   SOLE   2,609 0 0
ALLIANCE DATA SYSTEMS CORP COM 018581108 5,387 119,385 SH   SOLE   119,385 0 0
ALLIANT ENERGY CORP COM 018802108 1,045 21,834 SH   SOLE   21,834 0 0
ALPHABET INC CAP STK CL A 02079K305 44,124 31,116 SH   SOLE   31,116 0 0
ALPHABET INC CAP STK CL C 02079K107 2,277 1,611 SH   SOLE   1,611 0 0
ALTRIA GROUP INC COM 02209S103 639 16,269 SH   SOLE   16,269 0 0
AMAZON COM INC COM 023135106 55,311 20,049 SH   SOLE   20,049 0 0
AMCOR PLC ORD G0250X107 156 15,300 SH   SOLE   15,300 0 0
AMERICAN ELEC PWR CO INC COM 025537101 604 7,590 SH   SOLE   7,590 0 0
AMERICAN EXPRESS CO COM 025816109 1,029 10,804 SH   SOLE   10,804 0 0
AMERICAN TOWER CORP NEW COM 03027X100 1,997 7,725 SH   SOLE   7,725 0 0
AMGEN INC COM 031162100 2,904 12,311 SH   SOLE   12,311 0 0
ANTHEM INC COM 036752103 526 2,000 SH   SOLE   2,000 0 0
AON PLC SHS CL A G0403H108 501 2,600 SH   SOLE   2,600 0 0
APACHE CORP COM 037411105 203 15,000 SH   SOLE   15,000 0 0
APPLE INC COM 037833100 58,343 159,931 SH   SOLE   159,931 0 0
ARCHER DANIELS MIDLAND CO COM 039483102 277 6,937 SH   SOLE   6,937 0 0
AT&T INC COM 00206R102 2,150 71,109 SH   SOLE   71,109 0 0
ATLASSIAN CORP PLC CL A G06242104 286 1,585 SH   SOLE   1,585 0 0
AUTOMATIC DATA PROCESSING IN COM 053015103 1,170 7,857 SH   SOLE   7,857 0 0
BALL CORP COM 058498106 334 4,800 SH   SOLE   4,800 0 0
BAXTER INTL INC COM 071813109 752 8,733 SH   SOLE   8,733 0 0
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702 8,645 48,429 SH   SOLE   48,429 0 0
BERKSHIRE HATHAWAY INC DEL CL A 084670108 802 3 SH   SOLE   3 0 0
BIO-TECHNE CORP COM 09073M104 264 1,000 SH   SOLE   1,000 0 0
BK OF AMERICA CORP COM 060505104 326 13,747 SH   SOLE   13,747 0 0
BLACKLINE INC COM 09239B109 50,867 613,522 SH   SOLE   613,522 0 0
BLOOM ENERGY CORP COM CL A 093712107 134 12,342 SH   SOLE   12,342 0 0
BOEING CO COM 097023105 650 3,548 SH   SOLE   3,548 0 0
BP PLC SPONSORED ADR 055622104 764 32,747 SH   SOLE   32,747 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 223 1,900 SH   SOLE   1,900 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 2,057 34,976 SH   SOLE   34,976 0 0
BURLINGTON STORES INC COM 122017106 232 1,177 SH   SOLE   1,177 0 0
CABLE ONE INC COM 12685J105 591 333 SH   SOLE   333 0 0
CARRIER GLOBAL CORPORATION COM 14448C104 324 14,570 SH   SOLE   14,570 0 0
CARVANA CO CL A 146869102 29,325 243,972 SH   SOLE   243,972 0 0
CATERPILLAR INC DEL COM 149123101 524 4,145 SH   SOLE   4,145 0 0
CBOE GLOBAL MARKETS INC COM 12503M108 209 2,237 SH   SOLE   2,237 0 0
CHAMPIONX CORPORATION COM 15872M104 100 10,196 SH   SOLE   10,196 0 0
CHARTER COMMUNICATIONS INC N CL A 16119P108 211 413 SH   SOLE   413 0 0
CHEGG INC COM 163092109 227 3,371 SH   SOLE   3,371 0 0
CHEVRON CORP NEW COM 166764100 912 10,221 SH   SOLE   10,221 0 0
CIGNA CORP NEW COM 125523100 288 1,533 SH   SOLE   1,533 0 0
CINTAS CORP COM 172908105 217 814 SH   SOLE   814 0 0
CISCO SYS INC COM 17275R102 2,233 47,878 SH   SOLE   47,878 0 0
CME GROUP INC COM 12572Q105 894 5,498 SH   SOLE   5,498 0 0
COCA COLA CO COM 191216100 3,158 70,677 SH   SOLE   70,677 0 0
COMCAST CORP NEW CL A 20030N101 1,087 27,876 SH   SOLE   27,876 0 0
COPART INC COM 217204106 2,481 29,800 SH   SOLE   29,800 0 0
CORNING INC COM 219350105 238 9,173 SH   SOLE   9,173 0 0
COSTAR GROUP INC COM 22160N109 34,559 48,629 SH   SOLE   48,629 0 0
COSTCO WHSL CORP NEW COM 22160K105 35,947 118,553 SH   SOLE   118,553 0 0
DANAHER CORPORATION COM 235851102 578 3,267 SH   SOLE   3,267 0 0
DEERE & CO COM 244199105 299 1,900 SH   SOLE   1,900 0 0
DEXCOM INC COM 252131107 67,346 166,123 SH   SOLE   166,123 0 0
DIREXION SHS ETF TR DLY FIN BULL NEW 25459Y694 225 7,200 SH   SOLE   7,200 0 0
DISNEY WALT CO COM DISNEY 254687106 911 8,172 SH   SOLE   8,172 0 0
DNP SELECT INCOME FD COM 23325P104 111 10,215 SH   SOLE   10,215 0 0
DOMINION ENERGY INC COM 25746U109 474 5,839 SH   SOLE   5,839 0 0
DTE ENERGY CO COM 233331107 376 3,495 SH   SOLE   3,495 0 0
DUKE ENERGY CORP NEW COM NEW 26441C204 667 8,351 SH   SOLE   8,351 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 43,505 4,904,695 SH   SOLE   4,904,695 0 0
EBAY INC. COM 278642103 207 3,940 SH   SOLE   3,940 0 0
ECOLAB INC COM 278865100 2,419 12,157 SH   SOLE   12,157 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 24,035 347,774 SH   SOLE   347,774 0 0
EMERSON ELEC CO COM 291011104 397 6,406 SH   SOLE   6,406 0 0
ENBRIDGE INC COM 29250N105 220 7,234 SH   SOLE   7,234 0 0
ENDURANCE INTL GROUP HLDGS I COM 29272B105 3,110 771,640 SH   SOLE   771,640 0 0
ENTERGY CORP NEW COM 29364G103 233 2,489 SH   SOLE   2,489 0 0
ENTERPRISE PRODS PARTNERS L COM 293792107 409 22,518 SH   SOLE   22,518 0 0
EQUINIX INC COM 29444U700 1,316 1,874 SH   SOLE   1,874 0 0
EVO PMTS INC CL A COM 26927E104 571 25,029 SH   SOLE   25,029 0 0
EVOLENT HEALTH INC CL A 30050B101 72 10,073 SH   SOLE   10,073 0 0
EXELIXIS INC COM 30161Q104 19,560 823,925 SH   SOLE   823,925 0 0
EXXON MOBIL CORP COM 30231G102 14,286 319,448 SH   SOLE   319,448 0 0
FACEBOOK INC CL A 30303M102 42,211 185,894 SH   SOLE   185,894 0 0
FAIR ISAAC CORP COM 303250104 39,267 93,932 SH   SOLE   93,932 0 0
FASTENAL CO COM 311900104 21,800 508,873 SH   SOLE   508,873 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 364 2,711 SH   SOLE   2,711 0 0
FIFTH THIRD BANCORP COM 316773100 628 32,578 SH   SOLE   32,578 0 0
FISERV INC COM 337738108 336 3,440 SH   SOLE   3,440 0 0
GARTNER INC COM 366651107 267 2,200 SH   SOLE   2,200 0 0
GENERAL ELECTRIC CO COM 369604103 1,127 165,069 SH   SOLE   165,069 0 0
GENERAL MLS INC COM 370334104 760 12,322 SH   SOLE   12,322 0 0
GILEAD SCIENCES INC COM 375558103 315 4,092 SH   SOLE   4,092 0 0
GLAXOSMITHKLINE PLC SPONSORED ADR 37733W105 450 11,021 SH   SOLE   11,021 0 0
GLOBAL PMTS INC COM 37940X102 7,183 42,349 SH   SOLE   42,349 0 0
GRAINGER W W INC COM 384802104 763 2,428 SH   SOLE   2,428 0 0
GUARDANT HEALTH INC COM 40131M109 20,346 250,778 SH   SOLE   250,778 0 0
HOME DEPOT INC COM 437076102 2,172 8,671 SH   SOLE   8,671 0 0
HONEYWELL INTL INC COM 438516106 1,434 9,916 SH   SOLE   9,916 0 0
IDEXX LABS INC COM 45168D104 29,948 90,709 SH   SOLE   90,709 0 0
IHS MARKIT LTD SHS G47567105 769 10,180 SH   SOLE   10,180 0 0
ILLINOIS TOOL WKS INC COM 452308109 4,905 28,050 SH   SOLE   28,050 0 0
ILLUMINA INC COM 452327109 1,401 3,783 SH   SOLE   3,783 0 0
INOGEN INC COM 45780L104 513 14,438 SH   SOLE   14,438 0 0
INTEL CORP COM 458140100 3,097 51,771 SH   SOLE   51,771 0 0
INTERCONTINENTAL EXCHANGE IN COM 45866F104 51,480 562,004 SH   SOLE   562,004 0 0
INTERNATIONAL BUSINESS MACHS COM 459200101 1,008 8,347 SH   SOLE   8,347 0 0
INTUIT COM 461202103 3,545 11,968 SH   SOLE   11,968 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 1,023 1,795 SH   SOLE   1,795 0 0
INVESCO QQQ TR UNIT SER 1 46090E103 1,007 4,069 SH   SOLE   4,069 0 0
IQVIA HLDGS INC COM 46266C105 469 3,307 SH   SOLE   3,307 0 0
IRON MTN INC NEW COM 46284V101 2,895 110,918 SH   SOLE   110,918 0 0
ISHARES TR RUS 2000 GRW ETF 464287648 757 3,657 SH   SOLE   3,657 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 882 6,160 SH   SOLE   6,160 0 0
ISHARES TR CORE S&P500 ETF 464287200 4,735 15,288 SH   SOLE   15,288 0 0
ISHARES TR RUS 1000 GRW ETF 464287614 851 4,434 SH   SOLE   4,434 0 0
J2 GLOBAL INC COM 48123V102 30,509 482,660 SH   SOLE   482,660 0 0
JOHNSON & JOHNSON COM 478160104 9,443 67,150 SH   SOLE   67,150 0 0
JPMORGAN CHASE & CO COM 46625H100 5,665 60,229 SH   SOLE   60,229 0 0
KELLOGG CO COM 487836108 394 5,960 SH   SOLE   5,960 0 0
KIMBERLY CLARK CORP COM 494368103 954 6,749 SH   SOLE   6,749 0 0
KORNIT DIGITAL LTD SHS M6372Q113 52,923 991,432 SH   SOLE   991,432 0 0
LAUDER ESTEE COS INC CL A 518439104 648 3,433 SH   SOLE   3,433 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 30,061 268,761 SH   SOLE   268,761 0 0
LILLY ELI & CO COM 532457108 3,490 21,257 SH   SOLE   21,257 0 0
LINDE PLC SHS G5494J103 390 1,840 SH   SOLE   1,840 0 0
LOCKHEED MARTIN CORP COM 539830109 921 2,524 SH   SOLE   2,524 0 0
LOWES COS INC COM 548661107 46,316 342,775 SH   SOLE   342,775 0 0
LULULEMON ATHLETICA INC COM 550021109 3,212 10,293 SH   SOLE   10,293 0 0
LYFT INC CL A COM 55087P104 1,252 37,929 SH   SOLE   37,929 0 0
M & T BK CORP COM 55261F104 203 1,953 SH   SOLE   1,953 0 0
MARRIOTT INTL INC NEW CL A 571903202 443 5,170 SH   SOLE   5,170 0 0
MARSH & MCLENNAN COS INC COM 571748102 773 7,200 SH   SOLE   7,200 0 0
MASTERCARD INCORPORATED CL A 57636Q104 10,537 35,634 SH   SOLE   35,634 0 0
MCCORMICK & CO INC COM NON VTG 579780206 343 1,912 SH   SOLE   1,912 0 0
MCDONALDS CORP COM 580135101 1,646 8,921 SH   SOLE   8,921 0 0
MERCADOLIBRE INC COM 58733R102 4,761 4,830 SH   SOLE   4,830 0 0
MERCK & CO. INC COM 58933Y105 1,387 17,930 SH   SOLE   17,930 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 259 2,462 SH   SOLE   2,462 0 0
MICROSOFT CORP COM 594918104 21,893 107,576 SH   SOLE   107,576 0 0
MORNINGSTAR INC COM 617700109 20,104 142,615 SH   SOLE   142,615 0 0
NETFLIX INC COM 64110L106 3,630 7,978 SH   SOLE   7,978 0 0
NIKE INC CL B 654106103 1,892 19,293 SH   SOLE   19,293 0 0
NORFOLK SOUTHERN CORP COM 655844108 228 1,300 SH   SOLE   1,300 0 0
NORTHERN TR CORP COM 665859104 1,374 17,319 SH   SOLE   17,319 0 0
NOVARTIS AG SPONSORED ADR 66987V109 231 2,640 SH   SOLE   2,640 0 0
NVIDIA CORPORATION COM 67066G104 2,964 7,803 SH   SOLE   7,803 0 0
OGE ENERGY CORP COM 670837103 282 9,300 SH   SOLE   9,300 0 0
ORACLE CORP COM 68389X105 1,011 18,293 SH   SOLE   18,293 0 0
OREILLY AUTOMOTIVE INC COM 67103H107 1,063 2,520 SH   SOLE   2,520 0 0
OTIS WORLDWIDE CORP COM 68902V107 447 7,857 SH   SOLE   7,857 0 0
PACKAGING CORP AMER COM 695156109 542 5,434 SH   SOLE   5,434 0 0
PAPA JOHNS INTL INC COM 698813102 551 6,936 SH   SOLE   6,936 0 0
PAYCHEX INC COM 704326107 3,012 39,766 SH   SOLE   39,766 0 0
PAYLOCITY HLDG CORP COM 70438V106 365 2,500 SH   SOLE   2,500 0 0
PAYPAL HLDGS INC COM 70450Y103 53,085 304,683 SH   SOLE   304,683 0 0
PEPSICO INC COM 713448108 5,684 42,979 SH   SOLE   42,979 0 0
PFIZER INC COM 717081103 2,508 76,700 SH   SOLE   76,700 0 0
PINTEREST INC CL A 72352L106 20,169 909,741 SH   SOLE   909,741 0 0
POOL CORPORATION COM 73278L105 250 920 SH   SOLE   920 0 0
PORTFOLIO RECOVERY ASSOCS IN NOTE 3.000% 8/0 73640QAB1 81 82,000 SH   SOLE   82,000 0 0
PRA GROUP INC COM 69354N106 252 6,520 SH   SOLE   6,520 0 0
PROCTER AND GAMBLE CO COM 742718109 4,394 36,748 SH   SOLE   36,748 0 0
PROGRESSIVE CORP OHIO COM 743315103 47,582 593,964 SH   SOLE   593,964 0 0
PROTO LABS INC COM 743713109 640 5,690 SH   SOLE   5,690 0 0
QUALCOMM INC COM 747525103 251 2,750 SH   SOLE   2,750 0 0
QUINSTREET INC COM 74874Q100 20,248 1,935,768 SH   SOLE   1,935,768 0 0
RAYTHEON TECHNOLOGIES CORP COM 75513E101 1,218 19,762 SH   SOLE   19,762 0 0
REALPAGE INC COM 75606N109 38,278 588,794 SH   SOLE   588,794 0 0
S&P GLOBAL INC COM 78409V104 846 2,569 SH   SOLE   2,569 0 0
SALESFORCE COM INC COM 79466L302 41,104 219,422 SH   SOLE   219,422 0 0
SCHWAB CHARLES CORP COM 808513105 288 8,547 SH   SOLE   8,547 0 0
SHOPIFY INC CL A 82509L107 14,352 15,120 SH   SOLE   15,120 0 0
SNAP INC CL A 83304A106 804 34,216 SH   SOLE   34,216 0 0
SNAP ON INC COM 833034101 277 2,000 SH   SOLE   2,000 0 0
SOUTHERN CO COM 842587107 262 5,058 SH   SOLE   5,058 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103 1,442 4,676 SH   SOLE   4,676 0 0
SPROTT PHYSICAL GOLD & SILVE TR UNIT 85208R101 2,229 131,920 SH   SOLE   131,920 0 0
SPROTT PHYSICAL GOLD TR UNIT 85207H104 2,633 183,978 SH   SOLE   183,978 0 0
SPROTT PHYSICAL SILVER TR TR UNIT 85207K107 106 16,000 SH   SOLE   16,000 0 0
STARBUCKS CORP COM 855244109 1,455 19,772 SH   SOLE   19,772 0 0
STATE STR CORP COM 857477103 408 6,423 SH   SOLE   6,423 0 0
STRYKER CORPORATION COM 863667101 610 3,386 SH   SOLE   3,386 0 0
SVB FINANCIAL GROUP COM 78486Q101 32,988 153,054 SH   SOLE   153,054 0 0
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADS 874039100 12,101 213,158 SH   SOLE   213,158 0 0
TANDEM DIABETES CARE INC COM NEW 875372203 43,597 440,731 SH   SOLE   440,731 0 0
TARGET CORP COM 87612E106 41,181 343,375 SH   SOLE   343,375 0 0
TELADOC HEALTH INC COM 87918A105 4,788 25,090 SH   SOLE   25,090 0 0
TELEFLEX INCORPORATED COM 879369106 910 2,500 SH   SOLE   2,500 0 0
TESLA INC COM 88160R101 245 227 SH   SOLE   227 0 0
TEXAS INSTRS INC COM 882508104 411 3,240 SH   SOLE   3,240 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 284 783 SH   SOLE   783 0 0
TJX COS INC NEW COM 872540109 690 13,646 SH   SOLE   13,646 0 0
TRANSDIGM GROUP INC COM 893641100 1,017 2,300 SH   SOLE   2,300 0 0
TRANSUNION COM 89400J107 24,893 285,995 SH   SOLE   285,995 0 0
ULTA BEAUTY INC COM 90384S303 332 1,630 SH   SOLE   1,630 0 0
UNILEVER N V N Y SHS NEW 904784709 392 7,351 SH   SOLE   7,351 0 0
UNION PAC CORP COM 907818108 1,005 5,944 SH   SOLE   5,944 0 0
UNITED PARCEL SERVICE INC CL B 911312106 455 4,089 SH   SOLE   4,089 0 0
US BANCORP DEL COM NEW 902973304 399 10,826 SH   SOLE   10,826 0 0
VALMONT INDS INC COM 920253101 530 4,662 SH   SOLE   4,662 0 0
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363 234 826 SH   SOLE   826 0 0
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874 1,007 20,000 SH   SOLE   20,000 0 0
VANGUARD SCOTTSDALE FDS SHRT TRM CORP BD 92206C409 385 4,656 SH   SOLE   4,656 0 0
VEEVA SYS INC CL A COM 922475108 42,069 179,462 SH   SOLE   179,462 0 0
VERISK ANALYTICS INC COM 92345Y106 426 2,500 SH   SOLE   2,500 0 0
VERIZON COMMUNICATIONS INC COM 92343V104 2,503 45,409 SH   SOLE   45,409 0 0
VISA INC COM CL A 92826C839 62,746 324,821 SH   SOLE   324,821 0 0
WAITR HLDGS INC COM 930752100 121 46,080 SH   SOLE   46,080 0 0
WALGREENS BOOTS ALLIANCE INC COM 931427108 705 16,636 SH   SOLE   16,636 0 0
WALMART INC COM 931142103 1,204 10,053 SH   SOLE   10,053 0 0
WASTE MGMT INC DEL COM 94106L109 649 6,132 SH   SOLE   6,132 0 0
WEC ENERGY GROUP INC COM 92939U106 608 6,941 SH   SOLE   6,941 0 0
WELLS FARGO CO NEW COM 949746101 477 18,614 SH   SOLE   18,614 0 0
WEX INC COM 96208T104 274 1,660 SH   SOLE   1,660 0 0
WEYERHAEUSER CO MTN BE COM NEW 962166104 265 11,813 SH   SOLE   11,813 0 0
WIX COM LTD SHS M98068105 384 1,500 SH   SOLE   1,500 0 0
WORKDAY INC CL A 98138H101 28,408 151,620 SH   SOLE   151,620 0 0
WW INTL INC COM 98262P101 220 8,673 SH   SOLE   8,673 0 0
YUM BRANDS INC COM 988498101 1,050 12,086 SH   SOLE   12,086 0 0
YUM CHINA HLDGS INC COM 98850P109 507 10,541 SH   SOLE   10,541 0 0
ZEBRA TECHNOLOGIES CORPORATI CL A 989207105 9,113 35,606 SH   SOLE   35,606 0 0
ZOETIS INC CL A 98978V103 39,677 289,529 SH   SOLE   289,529 0 0