The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8

COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories Common 002824100 44,458 486,250 SH   SOLE   486,250 0 0
AbbVie Inc. Common 00287Y109 52,401 533,725 SH   SOLE   533,725 0 0
ABIOMED, Inc. Common 003654100 3,815 15,794 SH   SOLE   15,794 0 0
AC Immune SA Shares H00263105 1,156 171,813 SH   SOLE   171,813 0 0
Acadia Healthcare Company, Inc. Common 00404A109 3,296 131,200 SH   SOLE   131,200 0 0
ACADIA Pharmaceuticals Inc. Common 004225108 12,154 250,743 SH   SOLE   250,743 0 0
Acceleron Pharma Inc. Common 00434H108 3,869 40,606 SH   SOLE   40,606 0 0
Addus HomeCare Corp. Common 006739106 1,478 15,969 SH   SOLE   15,969 0 0
Aerie Pharmaceuticals, Inc. Common 00771V108 984 66,688 SH   SOLE   66,688 0 0
Aerpio Pharmaceuticals, Inc. Common 00810B105 322 257,554 SH   SOLE   257,554 0 0
Agilent Technologies, Inc. Common 00846U101 4,642 52,525 SH   SOLE   52,525 0 0
Agios Pharmaceuticals, Inc. Common 00847X104 9,999 186,964 SH   SOLE   186,964 0 0
Alcon Inc. Ordinary Shares H01301128 2,103 36,686 SH   SOLE   36,686 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 43,180 384,709 SH   SOLE   384,709 0 0
Align Technology, Inc. Common 016255101 2,756 10,041 SH   SOLE   10,041 0 0
Alkermes plc Shares G01767105 3,297 169,930 SH   SOLE   169,930 0 0
Allakos Inc. Common 01671P100 4,628 64,397 SH   SOLE   64,397 0 0
Allogene Therapeutics, Inc. Common 019770106 9,252 216,069 SH   SOLE   216,069 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 18,642 125,867 SH   SOLE   125,867 0 0
Amarin Corporation plc Sponsored ADR 023111206 5,879 849,588 SH   SOLE   849,588 0 0
Amedisys, Inc. Common 023436108 3,851 19,395 SH   SOLE   19,395 0 0
AmerisourceBergen Corp. Common 03073E105 8,127 80,645 SH   SOLE   80,645 0 0
Amgen Inc. Common 031162100 144,337 611,962 SH   SOLE   611,962 0 0
Amicus Therapeutics, Inc. Common 03152W109 5,082 336,984 SH   SOLE   336,984 0 0
AnaptysBio, Inc. Common 032724106 2,642 118,261 SH   SOLE   118,261 0 0
Anthem, Inc. Common 036752103 10,583 40,242 SH   SOLE   40,242 0 0
Apellis Pharmaceuticals, Inc. Common 03753U106 5,666 173,494 SH   SOLE   173,494 0 0
ARCA biopharma, Inc. Common 00211Y506 215 32,461 SH   SOLE   32,461 0 0
Ardelyx, Inc. Common 039697107 4,205 607,698 SH   SOLE   607,698 0 0
Arena Pharmaceuticals, Inc. Common 040047607 5,540 88,002 SH   SOLE   88,002 0 0
argenx SE Sponsored ADR 04016X101 10,130 44,977 SH   SOLE   44,977 0 0
Arrowhead Pharmaceuticals, Inc. Common 04280A100 3,204 74,186 SH   SOLE   74,186 0 0
Ascendis Pharma A/S Sponsored ADR 04351P101 8,502 57,482 SH   SOLE   57,482 0 0
Assertio Holdings, Inc. Common 04546C106 1,407 1,642,302 SH   SOLE   1,642,302 0 0
AstraZeneca PLC Sponsored ADR 046353108 12,418 234,798 SH   SOLE   234,798 0 0
Atreca, Inc. Class A Common 04965G109 7,500 352,424 SH   SOLE   352,424 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 1,475 90,788 SH   SOLE   90,788 0 0
Avadel Pharmaceuticals plc Sponsored ADR 05337M104 1,888 233,612 SH   SOLE   233,612 0 0
AVROBIO, Inc. Common 05455M100 2,453 140,581 SH   SOLE   140,581 0 0
Axonics Modulation Technologies, Inc. Common 05465P101 987 28,100 SH   SOLE   28,100 0 0
Axsome Therapeutics, Inc. Common 05464T104 2,599 31,591 SH   SOLE   31,591 0 0
Bausch Health Companies Inc. Common 071734107 2,166 118,412 SH   SOLE   118,412 0 0
Baxter International Inc. Common 071813109 10,506 122,023 SH   SOLE   122,023 0 0
Becton, Dickinson and Co. Common 075887109 18,604 77,754 SH   SOLE   77,754 0 0
BeiGene, Ltd. Sponsored ADR 07725L102 14,127 74,984 SH   SOLE   74,984 0 0
Bellicum Pharmaceuticals, Inc. Common 079481404 45 6,000 SH   SOLE   6,000 0 0
Bio-Techne Corp. Common 09073M104 13,655 51,710 SH   SOLE   51,710 0 0
Biogen Inc. Common 09062X103 62,499 233,599 SH   SOLE   233,599 0 0
Biohaven Pharmaceutical Holding Company Ltd. Common G11196105 2,506 34,277 SH   SOLE   34,277 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 30,263 245,362 SH   SOLE   245,362 0 0
bluebird bio, Inc. Common 09609G100 5,139 84,194 SH   SOLE   84,194 0 0
Blueprint Medicines Corp. Common 09627Y109 9,224 118,256 SH   SOLE   118,256 0 0
Boston Scientific Corp. Common 101137107 22,644 644,935 SH   SOLE   644,935 0 0
BridgeBio Pharma, Inc. Common 10806X102 1,279 39,228 SH   SOLE   39,228 0 0
Bristol-Myers Squibb Co. Common 110122108 57,477 977,505 SH   SOLE   977,505 0 0
Bristol-Myers Squibb Co. Right 110122157 5,276 1,473,710 SH   SOLE   1,473,710 0 0
Celldex Therapeutics, Inc. Common 15117B202 92 7,053 SH   SOLE   7,053 0 0
Cellectis Sponsored ADR 15117K103 1,961 110,147 SH   SOLE   110,147 0 0
Centene Corp. Common 15135B101 18,315 288,194 SH   SOLE   288,194 0 0
Cerner Corp. Common 156782104 5,587 81,500 SH   SOLE   81,500 0 0
Charles River Laboratories International, Inc. Common 159864107 3,220 18,467 SH   SOLE   18,467 0 0
Cidara Therapeutics, Inc. Common 171757107 720 195,256 SH   SOLE   195,256 0 0
Cigna Corp. Common 125523100 15,010 79,988 SH   SOLE   79,988 0 0
Clearside Biomedical, Inc. Common 185063104 311 165,330 SH   SOLE   165,330 0 0
Coherus Biosciences, Inc. Common 19249H103 3,627 203,103 SH   SOLE   203,103 0 0
Community Health Systems, Inc. Common 203668108 354 117,735 SH   SOLE   117,735 0 0
Community Healthcare Trust Inc. Common 20369C106 609 14,900 SH   SOLE   14,900 0 0
Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 3,177 378,706 SH   SOLE   378,706 0 0
CRISPR Therapeutics AG Namen AKT H17182108 5,602 76,222 SH   SOLE   76,222 0 0
CVS Health Corp. Common 126650100 46,754 719,620 SH   SOLE   719,620 0 0
CymaBay Therapeutics, Inc. Common 23257D103 307 88,102 SH   SOLE   88,102 0 0
Danaher Corp. Common 235851102 28,178 159,352 SH   SOLE   159,352 0 0
Deciphera Pharmaceuticals, Inc. Common 24344T101 3,665 61,370 SH   SOLE   61,370 0 0
DENTSPLY SIRONA Inc. Common 24906P109 7,106 161,287 SH   SOLE   161,287 0 0
DexCom, Inc. Common 252131107 2,940 7,251 SH   SOLE   7,251 0 0
Diversified Healthcare Trust Common 25525P107 1,583 357,720 SH   SOLE   357,720 0 0
Editas Medicine, Inc. Common 28106W103 3,851 130,201 SH   SOLE   130,201 0 0
Edwards Lifesciences Corp. Common 28176E108 13,970 202,146 SH   SOLE   202,146 0 0
Eidos Therapeutics, Inc. Common 28249H104 953 20,000 SH   SOLE   20,000 0 0
Eli Lilly and Co. Common 532457108 33,958 206,837 SH   SOLE   206,837 0 0
Endo International plc Shares G30401106 1,823 531,570 SH   SOLE   531,570 0 0
Epizyme, Inc. Common 29428V104 3,336 207,752 SH   SOLE   207,752 0 0
Esperion Therapeutics, Inc. Common 29664W105 2,133 41,577 SH   SOLE   41,577 0 0
Evolent Health, Inc. Common 30050B101 1,645 231,027 SH   SOLE   231,027 0 0
Exact Sciences Corp. Common 30063P105 3,827 44,015 SH   SOLE   44,015 0 0
Exelixis, Inc. Common 30161Q104 22,172 933,949 SH   SOLE   933,949 0 0
Fate Therapeutics, Inc. Common 31189P102 6,370 185,672 SH   SOLE   185,672 0 0
FibroGen, Inc. Common 31572Q808 7,874 194,270 SH   SOLE   194,270 0 0
Five Star Senior Living Inc. Common 33832D205 95 24,237 SH   SOLE   24,237 0 0
Galapagos NV Sponsored ADR 36315X101 1,291 6,543 SH   SOLE   6,543 0 0
Galera Therapeutics, Inc. Common 36338D108 7,439 1,041,845 SH   SOLE   1,041,845 0 0
Genmab A/S Sponsored ADS 372303206 560 16,520 SH   SOLE   16,520 0 0
Gilead Sciences, Inc. Common 375558103 121,644 1,581,026 SH   SOLE   1,581,026 0 0
GlaxoSmithKline PLC Shares 37733W105 8,985 220,263 SH   SOLE   220,263 0 0
Global Blood Therapeutics, Inc. Common 37890U108 4,530 71,759 SH   SOLE   71,759 0 0
Global Medical REIT Inc. Common 37954A204 1,982 174,897 SH   SOLE   174,897 0 0
Grifols, S.A. Sponsored ADR 398438408 864 47,373 SH   SOLE   47,373 0 0
Guardant Health, Inc. Common 40131M109 6,606 81,422 SH   SOLE   81,422 0 0
GW Pharmaceuticals plc ADS 36197T103 3,074 25,051 SH   SOLE   25,051 0 0
Halozyme Therapeutics, Inc. Common 40637H109 1,874 69,917 SH   SOLE   69,917 0 0
HCA Healthcare, Inc. Common 40412C101 8,137 83,833 SH   SOLE   83,833 0 0
Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 1,006 10,055 SH   SOLE   10,055 0 0
Healthcare Realty Trust Inc. Common 421946104 3,047 104,024 SH   SOLE   104,024 0 0
Healthcare Trust of America, Inc. Common 42225P501 1,874 70,662 SH   SOLE   70,662 0 0
Healthpeak Properties, Inc. Common 42250P103 4,145 150,392 SH   SOLE   150,392 0 0
Heron Therapeutics, Inc. Common 427746102 1,930 131,183 SH   SOLE   131,183 0 0
Hologic, Inc. Common 436440101 1,856 32,564 SH   SOLE   32,564 0 0
Horizon Therapeutics plc Shares G46188101 22,796 410,153 SH   SOLE   410,153 0 0
Humana Inc. Common 444859102 18,808 48,506 SH   SOLE   48,506 0 0
IDEXX Laboratories, Inc. Common 45168D104 12,221 37,014 SH   SOLE   37,014 0 0
Illumina, Inc. Common 452327109 79,496 214,651 SH   SOLE   214,651 0 0
ImmunoGen, Inc. Common 45253H101 774 168,190 SH   SOLE   168,190 0 0
Immunomedics, Inc. Common 452907108 17,617 497,103 SH   SOLE   497,103 0 0
Incyte Corp. Common 45337C102 33,796 325,053 SH   SOLE   325,053 0 0
Innate Pharma SA Sponsored ADS B1G5FB909 858 137,734 SH   SOLE   137,734 0 0
Inogen, Inc. Common 45780L104 1,826 51,406 SH   SOLE   51,406 0 0
Inovio Pharmaceuticals, Inc. Common 45773H201 5,445 202,038 SH   SOLE   202,038 0 0
Insmed Inc. Common 457669307 2,710 98,387 SH   SOLE   98,387 0 0
Intellia Therapeutics, Inc. Common 45826J105 1,157 55,050 SH   SOLE   55,050 0 0
Intercept Pharmaceuticals, Inc. Common 45845P108 3,692 77,067 SH   SOLE   77,067 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 2,419 94,238 SH   SOLE   94,238 0 0
Intuitive Surgical, Inc. Common 46120E602 18,998 33,339 SH   SOLE   33,339 0 0
Ionis Pharmaceuticals, Inc. Common 462222100 11,391 193,201 SH   SOLE   193,201 0 0
Iovance Biotherapeutics, Inc. Common 462260100 7,441 271,073 SH   SOLE   271,073 0 0
IQVIA Holdings Inc. Common 46266C105 11,672 82,266 SH   SOLE   82,266 0 0
Jazz Pharmaceuticals plc Shares G50871105 7,443 67,456 SH   SOLE   67,456 0 0
Johnson & Johnson Common 478160104 116,727 830,031 SH   SOLE   830,031 0 0
Karuna Therapeutics, Inc. Common 48576A100 3,330 29,873 SH   SOLE   29,873 0 0
Kodiak Sciences Inc. Common 50015M109 1,253 23,153 SH   SOLE   23,153 0 0
Koninklijke Philips N.V. NY Reg Sh 500472303 2,613 55,796 SH   SOLE   55,796 0 0
Laboratory Corporation of America Holdings Sponsored ADR 50540R409 7,849 47,251 SH   SOLE   47,251 0 0
Ligand Pharmaceuticals Inc. Common 53220K504 3,421 30,590 SH   SOLE   30,590 0 0
LTC Properties, Inc. Common 502175102 6,867 182,293 SH   SOLE   182,293 0 0
Madrigal Pharmaceuticals, Inc. Common 558868105 1,511 13,340 SH   SOLE   13,340 0 0
Magenta Therapeutics, Inc. Common 55910K108 1,445 192,431 SH   SOLE   192,431 0 0
Mallinckrodt plc Sponsored ADR G5785G107 88 32,980 SH   SOLE   32,980 0 0
McKesson Corp. Common 58155Q103 16,498 107,537 SH   SOLE   107,537 0 0
Medical Properties Trust, Inc. Common 58463J304 7,741 411,743 SH   SOLE   411,743 0 0
Medpace Holdings, Inc. Common 58506Q109 1,755 18,871 SH   SOLE   18,871 0 0
Medtronic plc Shares G5960L103 43,602 475,489 SH   SOLE   475,489 0 0
Menlo Therapeutics Inc. Common 586858102 937 541,584 SH   SOLE   541,584 0 0
Merck & Co., Inc. Common 58933Y105 75,126 971,496 SH   SOLE   971,496 0 0
Mettler-Toledo International Inc. Common 592688105 4,932 6,123 SH   SOLE   6,123 0 0
Milestone Pharmaceuticals Inc. Common 59935V107 806 213,310 SH   SOLE   213,310 0 0
Mirati Therapeutics, Inc. Common 60468T105 8,995 78,784 SH   SOLE   78,784 0 0
Moderna, Inc. Common 60770K107 31,624 492,506 SH   SOLE   492,506 0 0
Molecular Templates, Inc. Common 608550109 583 42,313 SH   SOLE   42,313 0 0
Molina Healthcare, Inc. Common 60855R100 4,901 27,536 SH   SOLE   27,536 0 0
Momenta Pharmaceuticals, Inc. Common 60877T100 3,719 111,768 SH   SOLE   111,768 0 0
MorphoSys AG Sponsored ADS 617760202 614 19,390 SH   SOLE   19,390 0 0
Mylan N.V. Shares N59465109 16,253 1,010,754 SH   SOLE   1,010,754 0 0
MyoKardia, Inc. Common 62857M105 1,865 19,300 SH   SOLE   19,300 0 0
National Health Investors, Inc. Common 63633D104 610 10,038 SH   SOLE   10,038 0 0
Nektar Therapeutics Common 640268108 6,093 263,079 SH   SOLE   263,079 0 0
Neurocrine Biosciences, Inc. Common 64125C109 25,150 206,150 SH   SOLE   206,150 0 0
New Senior Investment Group Inc. Common 648691103 928 256,398 SH   SOLE   256,398 0 0
Novartis AG Sponsored ADR 66987V109 14,936 171,008 SH   SOLE   171,008 0 0
Novavax, Inc. Common 670002401 2,380 28,550 SH   SOLE   28,550 0 0
Novo Nordisk A/S Sponsored ADR 670100205 8,775 134,005 SH   SOLE   134,005 0 0
NovoCure Ltd. Ordinary Shares G6674U108 7,806 131,637 SH   SOLE   131,637 0 0
Omega Healthcare Investors, Inc. Common 681936100 9,110 306,433 SH   SOLE   306,433 0 0
Ovid Therapeutics Inc. Sponsored ADR 690469101 2,747 372,733 SH   SOLE   372,733 0 0
Pacific Biosciences of California, Inc. Common 69404D108 1,709 495,495 SH   SOLE   495,495 0 0
PerkinElmer, Inc. Common 714046109 3,776 38,494 SH   SOLE   38,494 0 0
Perrigo Company plc Shares G97822103 2,831 51,224 SH   SOLE   51,224 0 0
Pfizer Inc. Common 717081103 54,169 1,656,548 SH   SOLE   1,656,548 0 0
Physicians Realty Trust Common 71943U104 8,685 495,733 SH   SOLE   495,733 0 0
Pieris Pharmaceuticals, Inc. Common 720795103 4,493 1,449,269 SH   SOLE   1,449,269 0 0
Portola Pharmaceuticals, Inc. Sponsored ADR 737010108 1,965 109,246 SH   SOLE   109,246 0 0
PRA Health Sciences, Inc. Common 69354M108 13,962 143,508 SH   SOLE   143,508 0 0
Principia Biopharma Inc. Common 74257L108 3,611 60,390 SH   SOLE   60,390 0 0
PTC Therapeutics, Inc. Common 69366J200 6,131 120,827 SH   SOLE   120,827 0 0
Puma Biotechnology, Inc. Common 74587V107 744 71,340 SH   SOLE   71,340 0 0
Quest Diagnostics Inc. Common 74834L100 2,396 21,025 SH   SOLE   21,025 0 0
Quotient Ltd. Common G73268107 3,048 411,937 SH   SOLE   411,937 0 0
Reata Pharmaceuticals, Inc. Class A 75615P103 7,943 50,907 SH   SOLE   50,907 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 117,206 187,935 SH   SOLE   187,935 0 0
REGENXBIO Inc. Common 75901B107 799 21,700 SH   SOLE   21,700 0 0
ResMed Inc. Common 761152107 3,424 17,831 SH   SOLE   17,831 0 0
Revance Therapeutics, Inc. Common 761330109 2,096 85,840 SH   SOLE   85,840 0 0
Rocket Pharmaceuticals, Inc. Common 77313F106 6,049 289,029 SH   SOLE   289,029 0 0
Rubius Therapeutics, Inc. Common 78116T103 933 155,982 SH   SOLE   155,982 0 0
Sabra Health Care REIT, Inc. Common 78573L106 7,369 510,660 SH   SOLE   510,660 0 0
Sage Therapeutics Inc Common 78667J108 4,000 96,211 SH   SOLE   96,211 0 0
Sangamo Therapeutics, Inc. Common 800677106 1,343 149,835 SH   SOLE   149,835 0 0
Sanofi Sponsored ADR 80105N105 16,712 327,367 SH   SOLE   327,367 0 0
Sarepta Therapeutics, Inc. Common 803607100 22,468 140,129 SH   SOLE   140,129 0 0
Seattle Genetics, Inc. Common 812578102 40,876 240,559 SH   SOLE   240,559 0 0
Smith & Nephew plc Shares 83175M205 3,795 99,560 SH   SOLE   99,560 0 0
Spectrum Pharmaceuticals, Inc. Common 84763A108 388 114,670 SH   SOLE   114,670 0 0
STERIS plc Shares G8473T100 1,721 11,218 SH   SOLE   11,218 0 0
Stryker Corp. Common 863667101 29,593 164,230 SH   SOLE   164,230 0 0
Sutro Biopharma, Inc. Common 869367102 4,976 641,268 SH   SOLE   641,268 0 0
Syneos Health, Inc. Class A 87166B102 6,291 108,001 SH   SOLE   108,001 0 0
Takeda Pharmaceutical Company Ltd. Sponsored ADS 874060205 3,768 210,146 SH   SOLE   210,146 0 0
Teleflex Inc. Common 879369106 6,279 17,252 SH   SOLE   17,252 0 0
Tenet Healthcare Corp. Common 88033G407 1,752 96,736 SH   SOLE   96,736 0 0
Tetraphase Pharmaceuticals, Inc. Common 88165N204 108 42,965 SH   SOLE   42,965 0 0
Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 9,690 785,851 SH   SOLE   785,851 0 0
Theravance Biopharma, Inc. Common G8807B106 4,803 228,836 SH   SOLE   228,836 0 0
Thermo Fisher Scientific Inc. Common 883556102 38,417 106,025 SH   SOLE   106,025 0 0
Tricida, Inc. Common 89610F101 1,384 50,370 SH   SOLE   50,370 0 0
Trillium Therapeutics Inc. Common 89620X506 3,625 448,049 SH   SOLE   448,049 0 0
Turning Point Therapeutics, Inc. Common 90041T108 367 5,677 SH   SOLE   5,677 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108 7,625 97,480 SH   SOLE   97,480 0 0
uniQure N.V. Shares N90064101 2,841 63,039 SH   SOLE   63,039 0 0
United Therapeutics Corp. Class B 91307C102 7,685 63,513 SH   SOLE   63,513 0 0
Unitedhealth Group Inc. Common 91324P102 82,631 280,151 SH   SOLE   280,151 0 0
Universal Health Realty Income Trust Shares 91359E105 895 11,258 SH   SOLE   11,258 0 0
Ventas, Inc. Common 92276F100 7,621 208,108 SH   SOLE   208,108 0 0
Verona Pharma plc Sponsored ADR 925050106 1,182 253,179 SH   SOLE   253,179 0 0
Vertex Pharmaceuticals Inc. Common 92532F100 138,574 477,330 SH   SOLE   477,330 0 0
Waters Corporation Common 941848103 6,708 37,184 SH   SOLE   37,184 0 0
WaVe Life Sciences Ltd. Shares Y95308105 1,334 128,146 SH   SOLE   128,146 0 0
Welltower Inc. Common 95040Q104 10,510 203,083 SH   SOLE   203,083 0 0
Xencor, Inc. Common 98401F105 4,801 148,231 SH   SOLE   148,231 0 0
Y-mAbs Therapeutics, Inc. Common 984241109 3,307 76,548 SH   SOLE   76,548 0 0
Zai Lab Ltd. ADR 98887Q104 3,082 37,523 SH   SOLE   37,523 0 0
Zimmer Biomet Holdings, Inc. Common 98956P102 11,298 94,653 SH   SOLE   94,653 0 0
Zoetis Inc. Class A 98978V103 11,117 81,121 SH   SOLE   81,121 0 0
Zogenix, Inc. Common 98978L204 5,818 215,406 SH   SOLE   215,406 0 0
Zymeworks Inc. Common 98985W102 2,018 55,938 SH   SOLE   55,938 0 0