The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 6,788 76,000 SH   SOLE   76,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 22,608 900,000 SH   SOLE   900,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 51,136 1,055,000 SH   SOLE   1,055,000 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 2,663 1,644,015 SH   SOLE   1,644,015 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 19,889 1,986,910 SH   SOLE   1,986,910 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 27,819 575,000 SH   SOLE   575,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 14,712 1,590,528 SH   SOLE   1,590,528 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 63,091 1,179,720 SH   SOLE   1,179,720 0 0
AKERO THERAPEUTICS INC COM 00973Y108 6,055 242,985 SH   SOLE   242,985 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 20,596 183,500 SH   SOLE   183,500 0 0
ALIGN TECHNOLOGY INC COM 016255101 39,245 143,000 SH   SOLE   143,000 0 0
ALLAKOS INC COM 01671P100 17,177 239,032 SH   SOLE   239,032 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 18,861 440,468 SH   SOLE   440,468 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 51,098 345,000 SH   SOLE   345,000 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 32,178 4,650,000 SH   SOLE   4,650,000 0 0
AMGEN INC COM 031162100 29,718 126,000 SH   SOLE   126,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 15,334 1,016,821 SH   SOLE   1,016,821 0 0
ANAPTYSBIO INC COM 032724106 6,852 306,713 SH   SOLE   306,713 0 0
APPLIED THERAPEUTICS INC COM 03828A101 35,845 991,573 SH   SOLE   991,573 0 0
APREA THERAPEUTICS INC COM 03836J102 20,099 518,290 SH   SOLE   518,290 0 0
ARDELYX INC COM 039697107 34,705 5,015,109 SH   SOLE   5,015,109 0 0
ARGENX SE SPONSORED ADR 04016X101 64,754 287,500 SH   SOLE   287,500 0 0
ARVINAS INC COM 04335A105 16,148 481,468 SH   SOLE   481,468 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 31,577 213,500 SH   SOLE   213,500 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 34,955 1,498,915 SH   SOLE   1,498,915 0 0
BAXTER INTL INC COM 071813109 55,535 645,000 SH   SOLE   645,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 40,506 215,000 SH   SOLE   215,000 0 0
BELLUS HEALTH INC NEW COM NEW 07987C204 7,163 696,115 SH   SOLE   696,115 0 0
BIOGEN INC COM 09062X103 48,159 180,000 SH   SOLE   180,000 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 14,901 203,817 SH   SOLE   203,817 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 47,794 387,500 SH   SOLE   387,500 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 74,882 960,029 SH   SOLE   960,029 0 0
BOSTON SCIENTIFIC CORP COM 101137107 38,621 1,100,000 SH   SOLE   1,100,000 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 11,544 98,500 SH   SOLE   98,500 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 663 185,150 SH   SOLE   185,150 0 0
BURNING ROCK BIOTECH LTD SPONSORED ADS 12233L107 5,402 200,000 SH   SOLE   200,000 0 0
CENTENE CORP DEL COM 15135B101 83,568 1,315,000 SH   SOLE   1,315,000 0 0
CHIASMA INC COM 16706W102 7,491 1,392,312 SH   SOLE   1,392,312 0 0
CIGNA CORP NEW COM 125523100 30,212 161,000 SH   SOLE   161,000 0 0
COHERUS BIOSCIENCES INC COM 19249H103 36,171 2,025,275 SH   SOLE   2,025,275 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 20,563 1,175,000 SH   SOLE   1,175,000 0 0
COMPUGEN LTD ORD M25722105 16,978 1,130,375 SH   SOLE   1,130,375 0 0
CONMED CORP COM 207410101 12,958 180,000 SH   SOLE   180,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 15,496 515,680 SH   SOLE   515,680 0 0
COVETRUS INC COM 22304C100 14,983 837,500 SH   SOLE   837,500 0 0
CYTOKINETICS INC COM NEW 23282W605 1,825 77,417 SH   SOLE   77,417 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 19,082 8,000,000 PRN   SOLE   8,000,000 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 12,531 209,829 SH   SOLE   209,829 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 14,725 1,660,120 SH   SOLE   1,660,120 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 40,222 582,000 SH   SOLE   582,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100 51,557 832,500 SH   SOLE   832,500 0 0
EPIZYME INC COM 29428V104 33,792 2,104,084 SH   SOLE   2,104,084 0 0
EXACT SCIENCES CORP COM 30063P105 36,863 424,000 SH   SOLE   424,000 0 0
FIBROGEN INC COM 31572Q808 12,785 315,449 SH   SOLE   315,449 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 2,481 406,729 SH   SOLE   406,729 0 0
FRESHPET INC COM 358039105 39,822 476,000 SH   SOLE   476,000 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 16,370 937,041 SH   SOLE   937,041 0 0
GALAPAGOS NV SPON ADR 36315X101 34,526 175,000 SH   SOLE   175,000 0 0
GALERA THERAPEUTICS INC COM 36338D108 4,052 567,552 SH   SOLE   567,552 0 0
GAMIDA CELL LTD SHS M47364100 9,216 2,016,656 SH   SOLE   2,016,656 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 18,199 288,279 SH   SOLE   288,279 0 0
GLOBAL CORD BLOOD CORPORATIO SHS G39342103 2,868 925,000 SH   SOLE   925,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 15,746 15,573,000 PRN   SOLE   15,573,000 0 0
GUARDANT HEALTH INC COM 40131M109 15,415 190,000 SH   SOLE   190,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 14,732 120,043 SH   SOLE   120,043 0 0
HCA HEALTHCARE INC COM 40412C101 53,334 549,500 SH   SOLE   549,500 0 0
HEALTH CATALYST INC COM 42225T107 12,397 425,000 SH   SOLE   425,000 0 0
HEALTHEQUITY INC COM 42226A107 18,780 320,100 SH   SOLE   320,100 0 0
HOMOLOGY MEDICINES INC COM 438083107 5,341 351,638 SH   SOLE   351,638 0 0
HUMANA INC COM 444859102 74,060 191,000 SH   SOLE   191,000 0 0
IDEXX LABS INC COM 45168D104 41,270 125,000 SH   SOLE   125,000 0 0
IGM BIOSCIENCES INC COM 449585108 6,955 95,278 SH   SOLE   95,278 0 0
IMARA INC COM 45249V107 10,078 364,733 SH   SOLE   364,733 0 0
IMMUNOMEDICS INC COM 452907108 59,457 1,677,679 SH   SOLE   1,677,679 0 0
IMMUNOVANT INC COM 45258J102 11,014 452,319 SH   SOLE   452,319 0 0
INARI MED INC COM 45332Y109 3,875 80,000 SH   SOLE   80,000 0 0
INCYTE CORP COM 45337C102 25,993 250,000 SH   SOLE   250,000 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 5,861 6,000,000 PRN   SOLE   6,000,000 0 0
INSPIRE MED SYS INC COM 457730109 23,060 265,000 SH   SOLE   265,000 0 0
INSULET CORP COM 45784P101 56,918 293,000 SH   SOLE   293,000 0 0
INTERSECT ENT INC COM 46071F103 6,770 500,000 SH   SOLE   500,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 68,380 120,000 SH   SOLE   120,000 0 0
INVITAE CORP COM 46185L103 45,772 1,511,127 SH   SOLE   1,511,127 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 75,444 651,000 SH   SOLE   651,000 0 0
JOHNSON & JOHNSON COM 478160104 14,766 105,000 SH   SOLE   105,000 0 0
KARUNA THERAPEUTICS INC COM 48576A100 22,661 203,312 SH   SOLE   203,312 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 8,763 205,896 SH   SOLE   205,896 0 0
MACROGENICS INC COM 556099109 6,548 234,516 SH   SOLE   234,516 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 28,796 254,268 SH   SOLE   254,268 0 0
MERSANA THERAPEUTICS INC COM 59045L106 43,955 1,878,428 SH   SOLE   1,878,428 0 0
MIRATI THERAPEUTICS INC COM 60468T105 39,818 348,761 SH   SOLE   348,761 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 25,685 1,319,910 SH   SOLE   1,319,910 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 13,308 400,000 SH   SOLE   400,000 0 0
MYOKARDIA INC COM 62857M105 16,688 172,716 SH   SOLE   172,716 0 0
MYOVANT SCIENCES LTD COM G637AM102 10,483 508,411 SH   SOLE   508,411 0 0
NABRIVA THERAPEUTICS PLC SHS G63637105 720 1,067,664 SH   SOLE   1,067,664 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 166,713 1,366,500 SH   SOLE   1,366,500 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,673 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP COM 64157F103 46,115 386,000 SH   SOLE   386,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 683 500,000 PRN   SOLE   500,000 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 7,055 357,409 SH   SOLE   357,409 0 0
NOVAVAX INC COM NEW 670002401 47,559 570,598 SH   SOLE   570,598 0 0
NOVOCURE LTD ORD SHS G6674U108 10,378 175,000 SH   SOLE   175,000 0 0
OBSEVA SA COM H5861P103 8,385 1,423,552 SH   SOLE   1,423,552 0 0
ODONATE THERAPEUTICS INC COM 676079106 18,512 437,231 SH   SOLE   437,231 0 0
ONESPAWORLD HOLDINGS LIMITED COM P73684113 8,300 1,740,000 SH   SOLE   1,740,000 0 0
PACIRA BIOSCIENCES COM 695127100 48,535 925,000 SH   SOLE   925,000 0 0
PACIRA BIOSCIENCES NOTE 2.375% 4/0 695127AD2 1,094 1,000,000 PRN   SOLE   1,000,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 8,640 1,655,164 SH   SOLE   1,655,164 0 0
PASSAGE BIO INC COM 702712100 5,560 203,436 SH   SOLE   203,436 0 0
PENUMBRA INC COM 70975L107 37,016 207,000 SH   SOLE   207,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 5,262 1,143,925 SH   SOLE   1,143,925 0 0
PHREESIA INC COM 71944F106 18,424 651,500 SH   SOLE   651,500 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 41,488 2,306,196 SH   SOLE   2,306,196 0 0
PPD INC COM 69355F102 13,065 487,500 SH   SOLE   487,500 0 0
PROTHENA CORP PLC SHS G72800108 10,347 989,218 SH   SOLE   989,218 0 0
RADIUS HEALTH INC COM NEW 750469207 13,674 1,003,259 SH   SOLE   1,003,259 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,105 1,500,000 PRN   SOLE   1,500,000 0 0
REPARE THERAPEUTICS INC COM 760273102 8,525 274,815 SH   SOLE   274,815 0 0
RETROPHIN INC COM 761299106 20,905 1,024,261 SH   SOLE   1,024,261 0 0
RETROPHIN INC NOTE 2.500% 9/1 761299AB2 2,713 3,250,000 PRN   SOLE   3,250,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 11,420 512,111 SH   SOLE   512,111 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 10,793 5,897,642 SH   SOLE   5,897,642 0 0
ROYALTY PHARMA PLC SHS CL A G7709Q104 24,275 500,000 SH   SOLE   500,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 55,397 345,500 SH   SOLE   345,500 0 0
SEATTLE GENETICS INC COM 812578102 42,480 250,000 SH   SOLE   250,000 0 0
SHOCKWAVE MED INC COM 82489T104 9,356 197,500 SH   SOLE   197,500 0 0
SPERO THERAPEUTICS INC COM 84833T103 8,323 615,177 SH   SOLE   615,177 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 8,000 130,000 SH   SOLE   130,000 0 0
TELEFLEX INCORPORATED COM 879369106 47,317 130,000 SH   SOLE   130,000 0 0
TG THERAPEUTICS INC COM 88322Q108 13,303 682,926 SH   SOLE   682,926 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,460 1,500,000 PRN   SOLE   1,500,000 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 17,384 828,218 SH   SOLE   828,218 0 0
TRANSLATE BIO INC COM 89374L104 11,850 661,268 SH   SOLE   661,268 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 6,170 762,618 SH   SOLE   762,618 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 50,596 646,841 SH   SOLE   646,841 0 0
UNIQURE NV SHS N90064101 18,345 407,133 SH   SOLE   407,133 0 0
UNITEDHEALTH GROUP INC COM 91324P102 119,455 405,000 SH   SOLE   405,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 36,289 125,000 SH   SOLE   125,000 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 16,129 71,000 SH   SOLE   71,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105 6,467 515,711 SH   SOLE   515,711 0 0
ZAI LAB LTD ADR 98887Q104 66,792 813,246 SH   SOLE   813,246 0 0
ZOGENIX INC COM NEW 98978L204 11,236 415,982 SH   SOLE   415,982 0 0