The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACCELERON PHARMA INC COM 00434H108 40,168 421,619 SH   DFND 1 421,619 0 0
ADAPTHEALTH CORP COM CL A 00653Q102 22,368 1,389,341 SH   DFND 1 1,389,341 0 0
ADC THERAPEUTICS SA SHS H0036K147 23,405 500,000 SH   DFND 1 500,000 0 0
ADVERUM BIOTECHNOLOGIES INC COM 00773U108 17,412 833,895 SH   DFND 1 833,895 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 7,631 825,000 SH   DFND 1 825,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 7,295 494,216 SH   DFND 1 494,216 0 0
AKOUOS INC COM 00973J101 7,156 318,034 SH   DFND 1 318,034 0 0
ALECTOR INC COM 014442107 40,986 1,676,997 SH   DFND 1 1,676,997 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 20,877 186,000 SH   DFND 1 186,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 21,353 1,416,000 SH   DFND 1 1,416,000 0 0
APPLIED THERAPEUTICS INC COM 03828A101 10,063 278,359 SH   DFND 1 278,359 0 0
ARDELYX INC COM 039697107 17,726 2,561,554 SH   DFND 1 2,561,554 0 0
ARVINAS INC COM 04335A105 33,830 1,008,656 SH   DFND 1 1,008,656 0 0
ARYA SCIENCES ACQUISTION CO UNIT 06/09/2027 G31655114 5,798 500,000 SH   DFND 1 500,000 0 0
AVEO PHARMACEUTICALS INC COM NEW 053588307 1,839 357,101 SH   DFND 1 357,101 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 24,784 877,011 SH   DFND 1 877,011 0 0
AXONICS MODULATION TECHNOLOG COM 05465P101 49,456 1,408,603 SH   DFND 1 1,408,603 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 21,235 4,456,519 SH   DFND 1 4,456,519 0 0
BIODELIVERY SCIENCES INTL IN COM 09060J106 28,538 6,545,500 SH   DFND 1 6,545,500 0 0
BLACK DIAMOND THERAPEUTICS I COM 09203E105 22,598 536,001 SH   DFND 1 536,001 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 31,620 405,386 SH   DFND 1 405,386 0 0
BROOKDALE SR LIVING INC COM 112463104 41,037 13,910,899 SH   DFND 1 13,910,899 0 0
CABALETTA BIO INC COM 12674W109 5,172 464,252 SH   DFND 1 464,252 0 0
CARDIOVASCULAR SYS INC DEL COM 141619106 20,508 650,000 SH   DFND 1 650,000 0 0
CENTENE CORP DEL COM 15135B101 56,305 886,000 SH   DFND 1 886,000 0 0
CERUS CORP COM 157085101 14,551 2,204,700 SH   DFND 1 2,204,700 0 0
CLOVIS ONCOLOGY INC NOTE 2.500% 9/1 189464AB6 44,037 49,064,000 PRN   DFND 1 49,064,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 26,260 873,890 SH   DFND 1 873,890 0 0
DBV TECHNOLOGIES S A SPONSORED ADR 23306J101 22,627 5,154,155 SH   DFND 1 5,154,155 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 25,183 421,679 SH   DFND 1 421,679 0 0
DEXCOM INC NOTE 0.750%12/0 252131AH0 84,346 34,000,000 SH   DFND 1 34,000,000 0 0
DFP HEALTHCARE ACQUISITNS CO UNIT 03/31/2025 23343Q209 111,661 10,460,000 SH   DFND 1 10,460,000 0 0
EDITAS MEDICINE INC COM 28106W103 34,279 1,158,841 SH   DFND 1 1,158,841 0 0
ENDOLOGIX INC COM NEW 29266S304 764 950,000 SH   DFND 1 950,000 0 0
FATE THERAPEUTICS INC COM 31189P102 31,352 913,775 SH   DFND 1 913,775 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 21,960 1,257,000 SH   DFND 1 1,257,000 0 0
GENERATION BIO CO COM 37148K100 24,911 1,186,215 SH   DFND 1 1,186,215 0 0
GLAUKOS CORP COM 377322102 33,579 874,000 SH   DFND 1 874,000 0 0
HOLOGIC INC COM 436440101 78,101 1,370,186 SH   DFND 1 1,370,186 0 0
HORIZON PHARMA INVT LTD NOTE 2.500% 3/1 44052TAB7 280,641 144,832,000 PRN   DFND 1 144,832,000 0 0
HORIZON THERAPEUTICS PUB LTD SHS G46188101 108,448 1,951,211 SH   DFND 1 1,951,211 0 0
IMARA INC COM 45249V107 11,715 424,000 SH   DFND 1 424,000 0 0
IMMUNOMEDICS INC COM 452907108 90,762 2,561,000 SH   DFND 1 2,561,000 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 59,326 61,000,000 SH   DFND 1 61,000,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 3.250% 7/0 45845PAA6 43,410 57,791,000 PRN   DFND 1 57,791,000 0 0
INTERCEPT PHARMACEUTICALS IN NOTE 2.000% 5/1 45845PAB4 2,516 3,500,000 SH   DFND 1 3,500,000 0 0
INTERSECT ENT INC COM 46071F103 34,891 2,576,879 SH   DFND 1 2,576,879 0 0
ITAMAR MED LTD SPONSORED ADS 465437101 9,284 499,136 SH   DFND 1 499,136 0 0
IVERIC BIO INC COM 46583P102 29,414 5,767,409 SH   DFND 1 5,767,409 0 0
JAZZ INVESTMENTS I LTD NOTE 1.875% 8/1 472145AB7 19,588 20,000,000 SH   DFND 1 20,000,000 0 0
KEROS THERAPEUTICS INC COM 492327101 11,253 300,000 SH   DFND 1 300,000 0 0
LARIMAR THERAPEUTICS INC COM 517125100 66,107 5,144,539 SH   DFND 1 5,144,539 0 0
LONGVIEW ACQUISITION CORP UNIT 99/99/9999 543195200 22,220 2,200,000 SH   DFND 1 2,200,000 0 0
LUMOS PHARMA INC COM 55028X109 15,437 936,169 SH   DFND 1 936,169 0 0
MALLINCKRODT PUB LTD CO SHS G5785G107 5,281 1,970,687 SH   DFND 1 1,970,687 0 0
MCKESSON CORP COM 58155Q103 42,664 278,085 SH   DFND 1 278,085 0 0
MERIDIAN BIOSCIENCE INC COM 589584101 38,731 1,663,000 SH   DFND 1 1,663,000 0 0
MIRATI THERAPEUTICS INC COM 60468T105 20,537 179,885 SH   DFND 1 179,885 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 67,116 3,448,912 SH   DFND 1 3,448,912 0 0
MOLINA HEALTHCARE INC COM 60855R100 21,401 120,245 SH   DFND 1 120,245 0 0
MYLAN NV SHS EURO N59465109 195,394 12,151,362 SH   DFND 1 12,151,362 0 0
MYOKARDIA INC COM 62857M105 68,020 704,000 SH   DFND 1 704,000 0 0
NATERA INC COM 632307104 16,157 324,038 SH   DFND 1 324,038 0 0
NEOS THERAPEUTICS INC COM 64052L106 220 320,993 SH   DFND 1 320,993 0 0
NEURONETICS INC COM 64131A105 3,268 1,693,317 SH   DFND 1 1,693,317 0 0
NEVRO CORP NOTE 1.750% 6/0 64157FAA1 157,797 115,776,000 PRN   DFND 1 115,776,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 16,438 12,000,000 PRN   DFND 1 12,000,000 0 0
NUVASIVE INC NOTE 2.250% 3/1 670704AG0 93,062 85,000,000 SH   DFND 1 85,000,000 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 43,560 7,259,988 SH   DFND 1 7,259,988 0 0
ORIC PHARMACEUTICALS INC COM 68622P109 10,119 300,000 SH   DFND 1 300,000 0 0
OWENS & MINOR INC NEW COM 690732102 11,255 1,477,000 SH   DFND 1 1,477,000 0 0
OXFORD IMMUNOTEC GLOBAL PLC ORD SHS G6855A103 10,985 845,000 SH   DFND 1 845,000 0 0
PACIRA BIOSCIENCES COM 695127100 87,258 1,663,000 SH   DFND 1 1,663,000 0 0
PACIRA BIOSCIENCES NOTE 2.375% 4/0 695127AD2 21,894 20,000,000 SH   DFND 1 20,000,000 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102 17,898 1,013,495 SH   DFND 1 1,013,495 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 12,686 432,670 SH   DFND 1 432,670 0 0
PTC THERAPEUTICS INC NOTE 3.000% 8/1 69366JAB7 28,921 24,877,000 PRN   DFND 1 24,877,000 0 0
REATA PHARMACEUTICALS INC CL A 75615P103 40,841 261,765 SH   DFND 1 261,765 0 0
REVOLUTION MEDICINES INC COM 76155X100 56,712 1,796,383 SH   DFND 1 1,796,383 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 55,081 2,470,013 SH   DFND 1 2,470,013 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106 1,110 53,043 SH   DFND 1 53,043 0 0
SCHRODINGER INC COM 80810D103 123,269 1,346,167 SH   DFND 1 1,346,167 0 0
SELECT MED HLDGS CORP COM 81619Q105 8,322 565,000 SH   DFND 1 565,000 0 0
SELECTQUOTE INC COM 816307300 18,998 750,000 SH   DFND 1 750,000 0 0
SIENTRA INC COM 82621J105 16,110 4,162,804 SH   DFND 1 4,162,804 0 0
SILK RD MED INC COM 82710M100 31,208 744,998 SH   DFND 1 744,998 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 51,839 1,234,262 SH   DFND 1 1,234,262 0 0
TURNING POINT THERAPEUTICS I COM 90041T108 12,175 188,490 SH   DFND 1 188,490 0 0
VAPOTHERM INC COM 922107107 21,199 517,167 SH   DFND 1 517,167 0 0
VERICEL CORP COM 92346J108 42,250 3,057,161 SH   DFND 1 3,057,161 0 0
WINDTREE THERAPEUTICS INC COM 97382D303 141 20,148 SH   DFND 1 20,148 0 0
XERIS PHARMACEUTICALS INC COM 98422L107 8,455 3,178,551 SH   DFND 1 3,178,551 0 0
XERIS PHARMACEUTICALS INC NOTE 5.000% 7/1 98422LAA5 17,732 18,000,000 PRN   DFND 1 18,000,000 0 0