The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Abbott Laboratories Common 002824100 40,221 369,573 SH   SOLE   369,573 0 0
AbbVie Inc. Common 00287Y109 76,617 874,720 SH   SOLE   874,720 0 0
ABIOMED, Inc. Common 003654100 3,383 12,212 SH   SOLE   12,212 0 0
AC Immune SA Shares H00263105 838 171,813 SH   SOLE   171,813 0 0
Acadia Healthcare Co., Inc. Common 00404A109 3,868 131,200 SH   SOLE   131,200 0 0
ACADIA Pharmaceuticals Inc. Common 004225108 10,343 250,743 SH   SOLE   250,743 0 0
Adaptive Biotechnologies Corp. Common 00650F109 1,202 24,715 SH   SOLE   24,715 0 0
Addus HomeCare Corp. Common 006739106 1,509 15,969 SH   SOLE   15,969 0 0
Aerie Pharmaceuticals, Inc. Common 00771V108 785 66,688 SH   SOLE   66,688 0 0
Agilent Technologies, Inc. Common 00846U101 5,302 52,525 SH   SOLE   52,525 0 0
Agios Pharmaceuticals, Inc. Common 00847X104 6,544 186,964 SH   SOLE   186,964 0 0
Alcon Inc. Ordinary Shares H01301128 2,089 36,686 SH   SOLE   36,686 0 0
Alexion Pharmaceuticals, Inc. Common 015351109 30,529 266,791 SH   SOLE   266,791 0 0
Align Technology, Inc. Common 016255101 3,287 10,041 SH   SOLE   10,041 0 0
Alkermes plc Shares G01767105 2,816 169,930 SH   SOLE   169,930 0 0
Allakos Inc. Common 01671P100 5,245 64,397 SH   SOLE   64,397 0 0
Alnylam Pharmaceuticals, Inc. Common 02043Q107 25,465 174,894 SH   SOLE   174,894 0 0
Amarin Corp. plc Sponsored ADR 023111206 3,577 849,588 SH   SOLE   849,588 0 0
Amedisys, Inc. Common 023436108 4,586 19,395 SH   SOLE   19,395 0 0
AmerisourceBergen Corp. Common 03073E105 7,816 80,645 SH   SOLE   80,645 0 0
Amgen Inc. Common 031162100 154,585 608,218 SH   SOLE   608,218 0 0
Amicus Therapeutics, Inc. Common 03152W109 5,727 405,626 SH   SOLE   405,626 0 0
Anthem, Inc. Common 036752103 9,974 37,133 SH   SOLE   37,133 0 0
Apellis Pharmaceuticals, Inc. Common 03753U106 6,517 216,017 SH   SOLE   216,017 0 0
ARCA biopharma, Inc. Common 00211Y506 143 32,461 SH   SOLE   32,461 0 0
Ardelyx, Inc. Common 039697107 3,190 607,698 SH   SOLE   607,698 0 0
Arena Pharmaceuticals, Inc. Common 040047607 12,014 160,637 SH   SOLE   160,637 0 0
argenx SE Sponsored ADR 04016X101 16,194 61,687 SH   SOLE   61,687 0 0
Arrowhead Pharmaceuticals, Inc. Common 04280A100 3,194 74,186 SH   SOLE   74,186 0 0
Ascendis Pharma A/S Sponsored ADR 04351P101 19,405 125,746 SH   SOLE   125,746 0 0
Assertio Holdings, Inc. Common 04546C106 1,093 1,642,302 SH   SOLE   1,642,302 0 0
AstraZeneca PLC Sponsored ADR 046353108 18,869 344,333 SH   SOLE   344,333 0 0
Atreca, Inc. Class A Common 04965G109 4,923 352,424 SH   SOLE   352,424 0 0
Aurinia Pharmaceuticals Inc. Common 05156V102 4,428 300,611 SH   SOLE   300,611 0 0
Avadel Pharmaceuticals plc Sponsored ADR 05337M104 1,177 233,612 SH   SOLE   233,612 0 0
Axonics Modulation Technologies, Inc. Common 05465P101 990 19,400 SH   SOLE   19,400 0 0
Axsome Therapeutics, Inc. Common 05464T104 2,251 31,591 SH   SOLE   31,591 0 0
Bausch Health Companies Inc. Common 071734107 1,840 118,412 SH   SOLE   118,412 0 0
Baxter International Inc. Common 071813109 9,813 122,023 SH   SOLE   122,023 0 0
Becton, Dickinson and Co. Common 075887109 30,649 131,723 SH   SOLE   131,723 0 0
BeiGene, Ltd. Sponsored ADR 07725L102 8,101 28,280 SH   SOLE   28,280 0 0
Bellicum Pharmaceuticals, Inc. Common 079481404 39 6,000 SH   SOLE   6,000 0 0
Bio-Techne Corp. Common 09073M104 12,810 51,710 SH   SOLE   51,710 0 0
Biogen Inc. Common 09062X103 60,637 213,753 SH   SOLE   213,753 0 0
Biohaven Pharmaceutical Holding Co. Ltd. Common G11196105 2,228 34,277 SH   SOLE   34,277 0 0
BioMarin Pharmaceutical Inc. Common 09061G101 24,789 325,822 SH   SOLE   325,822 0 0
BioNTech SE Sponsored ADS 09075V102 3,018 43,595 SH   SOLE   43,595 0 0
bluebird bio, Inc. Common 09609G100 4,542 84,194 SH   SOLE   84,194 0 0
Blueprint Medicines Corp. Common 09627Y109 15,761 170,018 SH   SOLE   170,018 0 0
Boston Scientific Corp. Common 101137107 28,325 741,296 SH   SOLE   741,296 0 0
Bristol Myers Squibb Co. Common 110122108 56,982 945,140 SH   SOLE   945,140 0 0
Bristol Myers Squibb Co. Right 110122157 3,316 1,473,710 SH   SOLE   1,473,710 0 0
Celldex Therapeutics, Inc. Common 15117B202 105 7,053 SH   SOLE   7,053 0 0
Cellectis S.A. Sponsored ADR 15117K103 2,038 110,147 SH   SOLE   110,147 0 0
Centene Corp. Common 15135B101 26,733 458,313 SH   SOLE   458,313 0 0
Cerner Corp. Common 156782104 5,892 81,500 SH   SOLE   81,500 0 0
Charles River Laboratories International, Inc. Common 159864107 6,964 30,754 SH   SOLE   30,754 0 0
ChemoCentryx, Inc. Common 16383L106 7,916 144,447 SH   SOLE   144,447 0 0
Cigna Corp. Common 125523100 12,069 71,241 SH   SOLE   71,241 0 0
Clearside Biomedical, Inc. Common 185063104 255 165,330 SH   SOLE   165,330 0 0
Cogent Biosciences, Inc. Common 19240Q102 2,581 1,103,175 SH   SOLE   1,103,175 0 0
Coherus Biosciences, Inc. Common 19249H103 3,725 203,103 SH   SOLE   203,103 0 0
Community Health Systems, Inc. Common 203668108 497 117,735 SH   SOLE   117,735 0 0
Community Healthcare Trust Inc. Common 20369C106 697 14,900 SH   SOLE   14,900 0 0
Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 744 413,481 SH   SOLE   413,481 0 0
CRISPR Therapeutics AG Namen AKT H17182108 6,375 76,222 SH   SOLE   76,222 0 0
CVS Health Corp. Common 126650100 22,675 388,263 SH   SOLE   388,263 0 0
CymaBay Therapeutics, Inc. Common 23257D103 638 88,102 SH   SOLE   88,102 0 0
Danaher Corp. Common 235851102 14,549 67,567 SH   SOLE   67,567 0 0
Deciphera Pharmaceuticals, Inc. Common 24344T101 3,148 61,370 SH   SOLE   61,370 0 0
DENTSPLY SIRONA Inc. Common 24906P109 17,863 408,473 SH   SOLE   408,473 0 0
DexCom, Inc. Common 252131107 7,644 18,544 SH   SOLE   18,544 0 0
Dicerna Pharmaceuticals, Inc. Common 253031108 1,226 68,150 SH   SOLE   68,150 0 0
Diversified Healthcare Trust Common 25525P107 1,259 357,720 SH   SOLE   357,720 0 0
Edwards Lifesciences Corp. Common 28176E108 23,240 291,155 SH   SOLE   291,155 0 0
Eidos Therapeutics, Inc. Common 28249H104 1,011 20,000 SH   SOLE   20,000 0 0
Eli Lilly and Co. Common 532457108 26,294 177,637 SH   SOLE   177,637 0 0
Endo International plc Shares G30401106 1,754 531,570 SH   SOLE   531,570 0 0
Esperion Therapeutics, Inc. Common 29664W105 1,545 41,577 SH   SOLE   41,577 0 0
Exact Sciences Corp. Common 30063P105 1,545 15,150 SH   SOLE   15,150 0 0
Exelixis, Inc. Common 30161Q104 26,776 1,095,117 SH   SOLE   1,095,117 0 0
Fate Therapeutics, Inc. Common 31189P102 8,692 217,462 SH   SOLE   217,462 0 0
FibroGen, Inc. Common 31572Q808 7,988 194,270 SH   SOLE   194,270 0 0
Five Star Senior Living Inc. Common 33832D205 123 24,237 SH   SOLE   24,237 0 0
Galapagos NV Sponsored ADR 36315X101 929 6,543 SH   SOLE   6,543 0 0
Galera Therapeutics, Inc. Common 36338D108 9,418 1,041,845 SH   SOLE   1,041,845 0 0
Genmab A/S Sponsored ADS 372303206 6,765 184,779 SH   SOLE   184,779 0 0
Gilead Sciences, Inc. Common 375558103 103,864 1,643,683 SH   SOLE   1,643,683 0 0
GlaxoSmithKline PLC Shares 37733W105 1,220 32,400 SH   SOLE   32,400 0 0
Global Blood Therapeutics, Inc. Common 37890U108 3,957 71,759 SH   SOLE   71,759 0 0
Global Medical REIT Inc. Common 37954A204 2,361 174,897 SH   SOLE   174,897 0 0
Grifols, S.A. Sponsored ADR 398438408 822 47,373 SH   SOLE   47,373 0 0
Guardant Health, Inc. Common 40131M109 13,173 117,852 SH   SOLE   117,852 0 0
Harpoon Therapeutics, Inc. Common 41358P106 1,808 106,419 SH   SOLE   106,419 0 0
HCA Healthcare, Inc. Common 40412C101 10,215 81,933 SH   SOLE   81,933 0 0
Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 1,061 10,055 SH   SOLE   10,055 0 0
Healthcare Realty Trust Inc. Common 421946104 3,133 104,024 SH   SOLE   104,024 0 0
Healthcare Trust of America, Inc. Common 42225P501 1,837 70,662 SH   SOLE   70,662 0 0
Healthpeak Properties, Inc. Common 42250P103 4,083 150,392 SH   SOLE   150,392 0 0
Heron Therapeutics, Inc. Common 427746102 1,944 131,183 SH   SOLE   131,183 0 0
Hologic, Inc. Common 436440101 2,165 32,564 SH   SOLE   32,564 0 0
Horizon Therapeutics plc Shares G46188101 46,894 603,684 SH   SOLE   603,684 0 0
Humana Inc. Common 444859102 35,597 86,007 SH   SOLE   86,007 0 0
IDEXX Laboratories, Inc. Common 45168D104 13,686 34,814 SH   SOLE   34,814 0 0
Illumina, Inc. Common 452327109 86,868 281,054 SH   SOLE   281,054 0 0
ImmunoGen, Inc. Common 45253H101 605 168,190 SH   SOLE   168,190 0 0
Immunomedics, Inc. Common 452907108 18,990 223,336 SH   SOLE   223,336 0 0
Incyte Corp. Common 45337C102 13,695 152,605 SH   SOLE   152,605 0 0
Inogen, Inc. Common 45780L104 1,491 51,406 SH   SOLE   51,406 0 0
Insmed Inc. Common 457669307 3,162 98,387 SH   SOLE   98,387 0 0
Intercept Pharmaceuticals, Inc. Common 45845P108 3,195 77,067 SH   SOLE   77,067 0 0
Intra-Cellular Therapies, Inc. Common 46116X101 2,418 94,238 SH   SOLE   94,238 0 0
Intuitive Surgical, Inc. Common 46120E602 17,787 25,069 SH   SOLE   25,069 0 0
Ionis Pharmaceuticals, Inc. Common 462222100 9,167 193,201 SH   SOLE   193,201 0 0
Iovance Biotherapeutics, Inc. Common 462260100 8,924 271,073 SH   SOLE   271,073 0 0
IQVIA Holdings Inc. Common 46266C105 12,968 82,266 SH   SOLE   82,266 0 0
Jazz Pharmaceuticals plc Shares G50871105 9,619 67,456 SH   SOLE   67,456 0 0
Johnson & Johnson Common 478160104 81,408 546,805 SH   SOLE   546,805 0 0
Kadmon Holdings, Inc. Common 48283N106 2,799 714,008 SH   SOLE   714,008 0 0
Karuna Therapeutics, Inc. Common 48576A100 3,234 41,827 SH   SOLE   41,827 0 0
Karyopharm Therapeutics Inc. Common 48576U106 960 65,743 SH   SOLE   65,743 0 0
Koninklijke Philips N.V. NY Reg Sh 500472303 2,684 56,927 SH   SOLE   56,927 0 0
Kura Oncology, Inc. Common 50127T109 1,818 59,339 SH   SOLE   59,339 0 0
Laboratory Corporation of America Holdings Sponsored ADR 50540R409 13,179 70,003 SH   SOLE   70,003 0 0
LTC Properties, Inc. Common 502175102 6,355 182,293 SH   SOLE   182,293 0 0
Madrigal Pharmaceuticals, Inc. Common 558868105 1,584 13,340 SH   SOLE   13,340 0 0
Magenta Therapeutics, Inc. Common 55910K108 1,309 192,431 SH   SOLE   192,431 0 0
Mallinckrodt plc Sponsored ADR G5785G107 32 32,980 SH   SOLE   32,980 0 0
McKesson Corp. Common 58155Q103 16,015 107,537 SH   SOLE   107,537 0 0
Medical Properties Trust, Inc. Common 58463J304 7,259 411,743 SH   SOLE   411,743 0 0
Medpace Holdings, Inc. Common 58506Q109 2,109 18,871 SH   SOLE   18,871 0 0
Medtronic plc Shares G5960L103 55,588 534,914 SH   SOLE   534,914 0 0
Merck & Co., Inc. Common 58933Y105 87,654 1,056,706 SH   SOLE   1,056,706 0 0
Mettler-Toledo International Inc. Common 592688105 9,464 9,800 SH   SOLE   9,800 0 0
Milestone Pharmaceuticals Inc. Common 59935V107 1,561 213,310 SH   SOLE   213,310 0 0
Mirati Therapeutics, Inc. Common 60468T105 13,082 78,784 SH   SOLE   78,784 0 0
Moderna, Inc. Common 60770K107 32,570 460,359 SH   SOLE   460,359 0 0
Molecular Templates, Inc. Common 608550109 2,400 219,822 SH   SOLE   219,822 0 0
Molina Healthcare, Inc. Common 60855R100 7,810 42,669 SH   SOLE   42,669 0 0
MorphoSys AG Sponsored ADS 617760202 2,570 81,867 SH   SOLE   81,867 0 0
Mylan N.V. Shares N59465109 14,989 1,010,754 SH   SOLE   1,010,754 0 0
MyoKardia, Inc. Common 62857M105 2,631 19,300 SH   SOLE   19,300 0 0
National Health Investors, Inc. Common 63633D104 605 10,038 SH   SOLE   10,038 0 0
Nektar Therapeutics Common 640268108 4,364 263,079 SH   SOLE   263,079 0 0
Neurocrine Biosciences, Inc. Common 64125C109 6,078 63,203 SH   SOLE   63,203 0 0
New Senior Investment Group Inc. Common 648691103 1,026 256,398 SH   SOLE   256,398 0 0
Novartis AG Sponsored ADR 66987V109 13,177 151,525 SH   SOLE   151,525 0 0
Novavax, Inc. Common 670002401 1,249 11,523 SH   SOLE   11,523 0 0
Novo Nordisk A/S Sponsored ADR 670100205 9,304 134,005 SH   SOLE   134,005 0 0
NovoCure Ltd. Ordinary Shares G6674U108 13,006 116,845 SH   SOLE   116,845 0 0
NuCana plc Sponsored ADR 67022C106 2,382 460,672 SH   SOLE   460,672 0 0
Omega Healthcare Investors, Inc. Common 681936100 9,175 306,433 SH   SOLE   306,433 0 0
Ovid Therapeutics Inc. Sponsored ADR 690469101 2,139 372,733 SH   SOLE   372,733 0 0
PerkinElmer, Inc. Common 714046109 4,831 38,494 SH   SOLE   38,494 0 0
Perrigo Co. plc Shares G97822103 2,352 51,224 SH   SOLE   51,224 0 0
Pfizer Inc. Common 717081103 62,235 1,695,768 SH   SOLE   1,695,768 0 0
Physicians Realty Trust Common 71943U104 8,879 495,733 SH   SOLE   495,733 0 0
Pieris Pharmaceuticals, Inc. Common 720795103 3,000 1,449,269 SH   SOLE   1,449,269 0 0
PRA Health Sciences, Inc. Common 69354M108 8,067 79,526 SH   SOLE   79,526 0 0
Quest Diagnostics Inc. Common 74834L100 12,555 109,659 SH   SOLE   109,659 0 0
Reata Pharmaceuticals, Inc. Class A 75615P103 7,447 76,440 SH   SOLE   76,440 0 0
Regeneron Pharmaceuticals, Inc. Common 75886F107 116,092 207,388 SH   SOLE   207,388 0 0
REGENXBIO Inc. Common 75901B107 597 21,700 SH   SOLE   21,700 0 0
ResMed Inc. Common 761152107 16,641 97,069 SH   SOLE   97,069 0 0
Revance Therapeutics, Inc. Common 761330109 2,158 85,840 SH   SOLE   85,840 0 0
Sabra Health Care REIT, Inc. Common 78573L106 7,039 510,660 SH   SOLE   510,660 0 0
Sage Therapeutics, Inc. Common 78667J108 5,880 96,211 SH   SOLE   96,211 0 0
Sanofi Sponsored ADR 80105N105 19,161 381,920 SH   SOLE   381,920 0 0
Sarepta Therapeutics, Inc. Common 803607100 28,997 206,487 SH   SOLE   206,487 0 0
Seagen Inc. Common 812578102 65,987 337,204 SH   SOLE   337,204 0 0
Smith & Nephew plc Shares 83175M205 3,893 99,560 SH   SOLE   99,560 0 0
Spectrum Pharmaceuticals, Inc. Common 84763A108 468 114,670 SH   SOLE   114,670 0 0
STERIS plc Shares G8473T100 22,337 126,779 SH   SOLE   126,779 0 0
Stryker Corp. Common 863667101 32,887 157,830 SH   SOLE   157,830 0 0
Sutro Biopharma, Inc. Common 869367102 6,445 641,268 SH   SOLE   641,268 0 0
Syneos Health, Inc. Class A 87166B102 5,741 108,001 SH   SOLE   108,001 0 0
Takeda Pharmaceutic Sponsored ADS 874060205 3,749 210,146 SH   SOLE   210,146 0 0
Teleflex Inc. Common 879369106 5,873 17,252 SH   SOLE   17,252 0 0
Tenet Healthcare Corp. Common 88033G407 2,371 96,736 SH   SOLE   96,736 0 0
Tetraphase Pharmaceuticals, Inc. Common 881CVR013 9 42,965 SH   SOLE   42,965 0 0
Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 7,081 785,851 SH   SOLE   785,851 0 0
Theravance Biopharma, Inc. Common G8807B106 4,413 298,470 SH   SOLE   298,470 0 0
Thermo Fisher Scientific Inc. Common 883556102 13,008 29,461 SH   SOLE   29,461 0 0
Tricida, Inc. Common 89610F101 456 50,370 SH   SOLE   50,370 0 0
Trillium Therapeutics Inc. Common 89620X506 6,367 448,049 SH   SOLE   448,049 0 0
Turning Point Therapeutics, Inc. Common 90041T108 496 5,677 SH   SOLE   5,677 0 0
Ultragenyx Pharmaceutical Inc. Common 90400D108 8,012 97,480 SH   SOLE   97,480 0 0
uniQure N.V. Shares N90064101 2,322 63,039 SH   SOLE   63,039 0 0
United Therapeutics Corp. Class B 91307C102 6,415 63,513 SH   SOLE   63,513 0 0
Unitedhealth Group Inc. Common 91324P102 57,907 185,735 SH   SOLE   185,735 0 0
Universal Health Realty Income Trust Shares 91359E105 642 11,258 SH   SOLE   11,258 0 0
Ventas, Inc. Common 92276F100 8,732 208,108 SH   SOLE   208,108 0 0
Verona Pharma plc Sponsored ADR 925050106 2,967 475,402 SH   SOLE   475,402 0 0
Vertex Pharmaceuticals Inc. Common 92532F100 109,218 401,360 SH   SOLE   401,360 0 0
VYNE Therapeutics Inc. Common 92941V100 899 541,584 SH   SOLE   541,584 0 0
Waters Corp. Common 941848103 21,429 109,510 SH   SOLE   109,510 0 0
Welltower Inc. Common 95040Q104 11,188 203,083 SH   SOLE   203,083 0 0
Xencor, Inc. Common 98401F105 5,750 148,231 SH   SOLE   148,231 0 0
Y-mAbs Therapeutics, Inc. Common 984241109 2,939 76,548 SH   SOLE   76,548 0 0
Zai Lab Ltd. ADR 98887Q104 3,121 37,523 SH   SOLE   37,523 0 0
Zimmer Biomet Holdings, Inc. Common 98956P102 26,130 191,937 SH   SOLE   191,937 0 0
Zoetis Inc. Class A 98978V103 9,347 56,521 SH   SOLE   56,521 0 0
Zogenix, Inc. Common 98978L204 5,978 333,402 SH   SOLE   333,402 0 0
Zymeworks Inc. Common 98985W102 2,606 55,938 SH   SOLE   55,938 0 0