The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
21VIANET GROUP INC SPONSORED ADS A 90138A103 61,770 2,667,080 SH   DFND 8,23 2,667,080 0 0
AC IMMUNE SA SHS H00263105 12,757 2,614,095 SH   DFND 12,22,27 2,614,095 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 11,487 333,444 SH   DFND 11,13 333,444 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 3,545,792 12,061,337 SH   DFND 2,6,19,20,21 12,061,337 0 0
AMAZON COM INC COM 023135106 185,422 58,888 SH   DFND 2,19,21 58,888 0 0
ASLAN PHARMACEUTICALS LTD ADS 04522R101 2,703 1,422,475 SH   DFND 12,22,27 1,422,475 0 0
BEAM THERAPEUTICS INC COM 07373V105 82,591 3,354,641 SH   DFND 12,22,25 3,354,641 0 0
BEIGENE LTD SPONSORED ADR 07725L102 758,957 2,649,619 SH   DFND 12,22,27 2,649,619 0 0
BILL COM HLDGS INC COM 090043100 557,327 5,556,050 SH   DFND 12 5,556,050 0 0
BIONTECH SE SPONSORED ADS 09075V102 37,220 537,634 SH   DFND 3,7,23 537,634 0 0
BLACKROCK INC COM 09247X101 3,354,464 5,952,380 SH   DFND 2,8,19,21,23 5,952,380 0 0
CHENIERE ENERGY INC DEBT 4.875% 5/2 U16344AB6 265,744 261,827,403 PRN   DFND 6,19,21 261,827,403 0 0
CHINA BIOLOGIC PRODS HLDGS I COM G21515104 137,814 1,240,000 SH   DFND 12,22,27 1,240,000 0 0
COGNEX CORP COM 192422103 9,061 139,192 SH   DFND 2,19,21 139,192 0 0
COHERUS BIOSCIENCES INC COM 19249H103 135,370 7,381,116 SH   DFND 12,22,27 7,381,116 0 0
CORTEVA INC COM 22052L104 53,972 1,873,363 SH   DFND 9,21 1,873,363 0 0
DATADOG INC CL A COM 23804L103 6,246 61,142 SH   DFND 11,13 61,142 0 0
DELL TECHNOLOGIES INC CL C 24703L202 659,852 9,748,147 SH   DFND 17,23,26 9,748,147 0 0
DENALI THERAPEUTICS INC COM 24823R105 158,027 4,410,457 SH   DFND 12,22,25,27 4,410,457 0 0
DUCK CREEK TECHNOLOGIES INC SHS 264120106 238,119 5,241,451 SH   DFND 11 5,241,451 0 0
DUPONT DE NEMOURS INC COM 26614N102 103,934 1,873,363 SH   DFND 9,21 1,873,363 0 0
EROS STX GLOBAL CORPORATION SHS NEW G3788M114 6,089 2,755,310 SH   DFND 6,19,21 2,755,310 0 0
EVOQUA WATER TECHNOLOGIES CO COM 30057T105 128,120 6,037,705 SH   DFND 11,13 6,037,705 0 0
FARFETCH LTD ORD SH CL A 30744W107 71,437 2,839,308 SH   DFND 18,19,21 2,839,308 0 0
FTS INTERNATIONAL INC COM NEW 30283W203 6,908 2,080,857 SH   DFND 11,15 2,080,857 0 0
FUTU HLDGS LTD SPON ADS CL A 36118L106 16,300 569,528 SH   DFND 11 569,528 0 0
GLOBAL PMTS INC COM 37940X102 155,591 876,176 SH   DFND 12,14 876,176 0 0
GRACE W R & CO DEL NEW COM 38388F108 88,134 2,187,501 SH   DFND 9,21 2,187,501 0 0
GUARDANT HEALTH INC COM 40131M109 180,302 1,613,007 SH   DFND 12,22,25 1,613,007 0 0
HDFC BANK LTD SPONSORED ADS 40415F101 283,575 5,676,032 SH   DFND 2,9,19,21 5,676,032 0 0
HOMOLOGY MEDICINES INC COM 438083107 34,457 3,220,293 SH   DFND 12,22,25,27 3,220,293 0 0
ICICI BANK LIMITED ADR 45104G104 223,477 22,734,192 SH   DFND 2,4,9,12,19,21 22,734,192 0 0
IHS MARKIT LTD SHS G47567105 789,800 10,059,869 SH   DFND 8,23 10,059,869 0 0
ILLUMINA INC COM 452327109 17,139 55,452 SH   DFND 2,19,21 55,452 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 15,716 790,527 SH   DFND 9,12,21,22,25 790,527 0 0
ISHARES GOLD TRUST ISHARES 464285105 85,473 4,751,160 SH   DFND 2,19,21 4,751,160 0 0
ISHARES INC MSCI STH KOR ETF 464286772 27,234 416,800 SH   DFND 2,19,21 416,800 0 0
ISHARES INC MSCI TAIWAN ETF 46434G772 36,396 810,600 SH   DFND 2,19,21 810,600 0 0
ISHARES TR USD INV GRDE ETF 464288620 31,508 518,400 SH   DFND 2,19,21 518,400 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 33,853 226,000 SH   DFND 2,19,21 226,000 0 0
ISHARES TR US TREAS BD ETF 46429B267 55,792 1,996,150 SH   DFND 2,19,21 1,996,150 0 0
KEURIG DR PEPPER INC COM 49271V100 29,999 1,086,926 SH   DFND 11,13 1,086,926 0 0
KKR REAL ESTATE FIN TR INC COM 48251K100 40,317 2,439,024 SH   DFND 2,19,21 2,439,024 0 0
LUMEN TECHNOLOGIES INC COM 156700106 981,347 97,259,407 SH   DFND 2,3,7,10,19,21,23 97,259,407 0 0
MASTERCARD INCORPORATED CL A 57636Q104 765,175 2,262,692 SH   DFND 2,12,14,19,21 2,262,692 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 4,110 1,000,000 SH   DFND 12,22,27 1,000,000 0 0
PAYPAL HLDGS INC COM 70450Y103 1,849,892 9,388,884 SH   DFND 2,6,12,14,19,21 9,388,884 0 0
ROCKWELL AUTOMATION INC COM 773903109 9,800 44,409 SH   DFND 2,19,21 44,409 0 0
SCHWAB STRATEGIC TR US TIPS ETF 808524870 55,670 903,300 SH   DFND 2,19,21 903,300 0 0
SEA LTD SPONSORD ADS 81141R100 183,178 1,189,157 SH   DFND 2,9,19,21 1,189,157 0 0
SELECT SECTOR SPDR TR SBI CONS DISCR 81369Y407 22,294 151,680 SH   DFND 2,19,21 151,680 0 0
SELECT SECTOR SPDR TR SBI CONS STPLS 81369Y308 13,679 213,400 SH   DFND 2,19,21 213,400 0 0
SELECT SECTOR SPDR TR SBI HEALTHCARE 81369Y209 27,525 260,950 SH   DFND 2,19,21 260,950 0 0
SELECT SECTOR SPDR TR TECHNOLOGY 81369Y803 54,647 468,270 SH   DFND 2,19,21 468,270 0 0
SNOWFLAKE INC CL A 833445109 201,305 802,012 SH   DFND 2,9,19,21 802,012 0 0
STARBUCKS CORP COM 855244109 46,168 537,333 SH   DFND 9,21 537,333 0 0
TAL EDUCATION GROUP SPONSORED ADS 874080104 13,821 181,765 SH   DFND   181,765 0 0
TENCENT MUSIC ENTMT GROUP SPON ADS 88034P109 16,172 1,094,932 SH   DFND 8,11,13,23 1,094,932 0 0
THERMO FISHER SCIENTIFIC INC COM 883556102 663,643 1,503,087 SH   DFND 4,12,16 1,503,087 0 0
UBER TECHNOLOGIES INC COM 90353T100 401 10,988 SH   DFND 11,13 10,988 0 0
VIELA BIO INC COM 926613100 114,295 4,070,330 SH   DFND 12,22,25,27 4,070,330 0 0
VIR BIOTECHNOLOGY INC COM 92764N102 188,815 5,499,999 SH   DFND 12,22,25,27 5,499,999 0 0
VIRTU FINL INC CL A 928254101 261,865 11,380,503 SH   DFND 2,11,13,19,21 11,380,503 0 0
VISA INC COM CL A 92826C839 1,025,073 5,126,136 SH   DFND 2,12,14,19,21 5,126,136 0 0
VMWARE INC CL A COM 928563402 96,923 674,623 SH   DFND 9,21 674,623 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101 1,773 3,772 SH   DFND 11,13 3,772 0 0
ZTO EXPRESS CAYMAN INC SPONSORED ADS A 98980A105 364,328 12,176,750 SH   DFND 2,19,21 12,176,750 0 0