The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109 9,476 76,000 SH   SOLE   76,000 0 0
ACADIA HEALTHCARE COMPANY IN COM 00404A109 22,405 760,000 SH   SOLE   760,000 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 64,895 1,573,200 SH   SOLE   1,573,200 0 0
ACCOLADE INC COM 00437E102 12,633 325,000 SH   SOLE   325,000 0 0
ACELRX PHARMACEUTICALS INC COM 00444T100 5,358 3,773,585 SH   SOLE   3,773,585 0 0
ACLARIS THERAPEUTICS INC COM 00461U105 5,336 2,076,307 SH   SOLE   2,076,307 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107 15,856 1,986,910 SH   SOLE   1,986,910 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109 30,880 635,000 SH   SOLE   635,000 0 0
AEGLEA BIOTHERAPEUTICS INC COM 00773J103 11,277 1,590,528 SH   SOLE   1,590,528 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 55,353 1,581,509 SH   SOLE   1,581,509 0 0
AKERO THERAPEUTICS INC COM 00973Y108 13,025 423,040 SH   SOLE   423,040 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 25,747 225,000 SH   SOLE   225,000 0 0
ALIGN TECHNOLOGY INC COM 016255101 46,812 143,000 SH   SOLE   143,000 0 0
ALLAKOS INC COM 01671P100 19,677 241,582 SH   SOLE   241,582 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 49,477 339,814 SH   SOLE   339,814 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 18,314 4,350,000 SH   SOLE   4,350,000 0 0
AMICUS THERAPEUTICS INC COM 03152W109 14,456 1,023,821 SH   SOLE   1,023,821 0 0
ANAPTYSBIO INC COM 032724106 4,559 309,113 SH   SOLE   309,113 0 0
ANNEXON INC COM 03589W102 7,159 236,811 SH   SOLE   236,811 0 0
APPLIED THERAPEUTICS INC COM 03828A101 20,585 991,573 SH   SOLE   991,573 0 0
APREA THERAPEUTICS INC COM 03836J102 12,470 518,290 SH   SOLE   518,290 0 0
ARDELYX INC COM 039697107 26,654 5,076,867 SH   SOLE   5,076,867 0 0
ARGENX SE SPONSORED ADR 04016X101 75,475 287,500 SH   SOLE   287,500 0 0
ARVINAS INC COM 04335A105 11,367 481,468 SH   SOLE   481,468 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101 36,034 233,500 SH   SOLE   233,500 0 0
ASSEMBLY BIOSCIENCES INC COM 045396108 24,067 1,463,915 SH   SOLE   1,463,915 0 0
ATHIRA PHARMA INC COM 04746L104 20,356 1,102,702 SH   SOLE   1,102,702 0 0
ATRECA INC CL A COM 04965G109 6,298 450,830 SH   SOLE   450,830 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102 11,380 772,569 SH   SOLE   772,569 0 0
BAXTER INTL INC COM 071813109 51,871 645,000 SH   SOLE   645,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 61,585 215,000 SH   SOLE   215,000 0 0
BIOGEN INC COM 09062X103 48,935 172,500 SH   SOLE   172,500 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 26,628 350,000 SH   SOLE   350,000 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 88,322 952,773 SH   SOLE   952,773 0 0
BOSTON SCIENTIFIC CORP COM 101137107 42,031 1,100,000 SH   SOLE   1,100,000 0 0
BRIGHT HORIZONS FAM SOL IN D COM 109194100 25,163 165,500 SH   SOLE   165,500 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 417 185,150 SH   SOLE   185,150 0 0
CENTENE CORP DEL COM 15135B101 76,996 1,320,000 SH   SOLE   1,320,000 0 0
CHIASMA INC COM 16706W102 9,220 2,144,225 SH   SOLE   2,144,225 0 0
COHERUS BIOSCIENCES INC COM 19249H103 30,544 1,665,449 SH   SOLE   1,665,449 0 0
COLLEGIUM PHARMACEUTICAL INC COM 19459J104 24,464 1,175,000 SH   SOLE   1,175,000 0 0
COMPUGEN LTD ORD M25722105 18,408 1,132,775 SH   SOLE   1,132,775 0 0
CONMED CORP COM 207410101 14,161 180,000 SH   SOLE   180,000 0 0
CONSTELLATION PHARMCETICLS I COM 210373106 10,448 515,680 SH   SOLE   515,680 0 0
COVETRUS INC COM 22304C100 29,890 1,225,000 SH   SOLE   1,225,000 0 0
CYTOKINETICS INC COM NEW 23282W605 4,471 206,495 SH   SOLE   206,495 0 0
CYTOKINETICS INC NOTE 4.000%11/1 23282WAA8 17,795 8,000,000 PRN   SOLE   8,000,000 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201 7,119 1,647,920 SH   SOLE   1,647,920 0 0
EDWARDS LIFESCIENCES CORP COM 28176E108 46,455 582,000 SH   SOLE   582,000 0 0
ENCOMPASS HEALTH CORP COM 29261A100 45,356 698,000 SH   SOLE   698,000 0 0
EPIZYME INC COM 29428V104 30,441 2,551,659 SH   SOLE   2,551,659 0 0
EXACT SCIENCES CORP COM 30063P105 43,227 424,000 SH   SOLE   424,000 0 0
FIBROGEN INC COM 31572Q808 12,718 309,287 SH   SOLE   309,287 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 1,276 271,585 SH   SOLE   271,585 0 0
FRESHPET INC COM 358039105 56,551 506,500 SH   SOLE   506,500 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 11,389 947,541 SH   SOLE   947,541 0 0
GALAPAGOS NV SPON ADR 36315X101 24,834 175,000 SH   SOLE   175,000 0 0
GALERA THERAPEUTICS INC COM 36338D108 5,131 567,552 SH   SOLE   567,552 0 0
GAMIDA CELL LTD SHS M47364100 8,369 2,016,656 SH   SOLE   2,016,656 0 0
GLOBAL CORD BLOOD CORPORATIO SHS G39342103 3,203 904,800 SH   SOLE   904,800 0 0
GOODRX HLDGS INC COM CL A 38246G108 5,560 100,000 SH   SOLE   100,000 0 0
GOSSAMER BIO INC NOTE 5.000% 6/0 38341PAA0 16,049 15,573,000 PRN   SOLE   15,573,000 0 0
GUARDANT HEALTH INC COM 40131M109 21,238 190,000 SH   SOLE   190,000 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 11,603 119,188 SH   SOLE   119,188 0 0
HCA HEALTHCARE INC COM 40412C101 62,340 500,000 SH   SOLE   500,000 0 0
HEALTH CATALYST INC COM 42225T107 25,730 703,000 SH   SOLE   703,000 0 0
HEALTHEQUITY INC COM 42226A107 18,498 360,100 SH   SOLE   360,100 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 50,492 650,000 SH   SOLE   650,000 0 0
HUMANA INC COM 444859102 100,368 242,500 SH   SOLE   242,500 0 0
IDEXX LABS INC COM 45168D104 49,139 125,000 SH   SOLE   125,000 0 0
IGM BIOSCIENCES INC COM 449585108 1,459 19,762 SH   SOLE   19,762 0 0
IMARA INC COM 45249V107 7,301 358,943 SH   SOLE   358,943 0 0
IMMUNOMEDICS INC COM 452907108 134,985 1,587,500 SH   SOLE   1,587,500 0 0
IMMUNOVANT INC COM 45258J102 26,127 742,449 SH   SOLE   742,449 0 0
INCYTE CORP COM 45337C102 26,922 300,000 SH   SOLE   300,000 0 0
INOZYME PHARMA INC COM 45790W108 23,134 879,954 SH   SOLE   879,954 0 0
INSMED INC NOTE 1.750% 1/1 457669AA7 6,541 6,000,000 PRN   SOLE   6,000,000 0 0
INSPIRE MED SYS INC COM 457730109 30,456 236,000 SH   SOLE   236,000 0 0
INSULET CORP COM 45784P101 74,644 315,500 SH   SOLE   315,500 0 0
INTERSECT ENT INC COM 46071F103 8,155 500,000 SH   SOLE   500,000 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602 85,145 120,000 SH   SOLE   120,000 0 0
INVITAE CORP COM 46185L103 65,804 1,517,962 SH   SOLE   1,517,962 0 0
IRHYTHM TECHNOLOGIES INC COM 450056106 148,819 625,000 SH   SOLE   625,000 0 0
ITEOS THERAPEUTICS INC COM 46565G104 5,592 226,681 SH   SOLE   226,681 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105 8,199 57,500 SH   SOLE   57,500 0 0
KARUNA THERAPEUTICS INC COM 48576A100 18,874 244,106 SH   SOLE   244,106 0 0
KYMERA THERAPEUTICS INC COM 501575104 22,939 709,965 SH   SOLE   709,965 0 0
LEGEND BIOTECH CORP SPONSORED ADS 52490G102 7,784 252,138 SH   SOLE   252,138 0 0
MACROGENICS INC COM 556099109 6,616 262,641 SH   SOLE   262,641 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 30,189 254,268 SH   SOLE   254,268 0 0
MERSANA THERAPEUTICS INC COM 59045L106 35,107 1,885,428 SH   SOLE   1,885,428 0 0
MIRATI THERAPEUTICS INC COM 60468T105 57,912 348,761 SH   SOLE   348,761 0 0
MIRUM PHARMACEUTICALS INC COM 604749101 25,583 1,327,614 SH   SOLE   1,327,614 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 20,992 400,000 SH   SOLE   400,000 0 0
MYOVANT SCIENCES LTD COM G637AM102 7,204 512,711 SH   SOLE   512,711 0 0
NABRIVA THERAPEUTICS PLC SHS G63637105 569 1,067,664 SH   SOLE   1,067,664 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 140,922 1,465,500 SH   SOLE   1,465,500 0 0
NEUROCRINE BIOSCIENCES INC NOTE 2.250% 5/1 64125CAD1 1,385 1,000,000 PRN   SOLE   1,000,000 0 0
NEVRO CORP COM 64157F103 53,770 386,000 SH   SOLE   386,000 0 0
NEVRO CORP NOTE 2.750% 4/0 64157FAC7 775 500,000 PRN   SOLE   500,000 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105 5,735 360,454 SH   SOLE   360,454 0 0
NKARTA INC COM 65487U108 16,259 540,873 SH   SOLE   540,873 0 0
NOVAVAX INC COM NEW 670002401 63,461 585,705 SH   SOLE   585,705 0 0
NOVOCURE LTD ORD SHS G6674U108 19,479 175,000 SH   SOLE   175,000 0 0
NURIX THERAPEUTICS INC COM 67080M103 8,990 257,514 SH   SOLE   257,514 0 0
OAK STR HEALTH INC COM 67181A107 16,032 300,000 SH   SOLE   300,000 0 0
OBSEVA SA COM H5861P103 3,558 1,434,652 SH   SOLE   1,434,652 0 0
ODONATE THERAPEUTICS INC COM 676079106 6,573 489,432 SH   SOLE   489,432 0 0
ONESPAWORLD HOLDINGS LIMITED COM P73684113 11,310 1,740,000 SH   SOLE   1,740,000 0 0
PACIRA BIOSCIENCES COM 695127100 60,421 1,005,000 SH   SOLE   1,005,000 0 0
PACIRA BIOSCIENCES NOTE 2.375% 4/0 695127AD2 1,151 1,000,000 PRN   SOLE   1,000,000 0 0
PANACEA ACQUISITION CORP UNIT 99/99/9999 698102209 4,825 402,088 SH   SOLE   402,088 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 9,053 1,673,414 SH   SOLE   1,673,414 0 0
PASSAGE BIO INC COM 702712100 2,701 206,036 SH   SOLE   206,036 0 0
PENUMBRA INC COM 70975L107 30,906 159,000 SH   SOLE   159,000 0 0
PHASEBIO PHARMACEUTICALS INC COM 717224109 4,609 1,313,174 SH   SOLE   1,313,174 0 0
PHREESIA INC COM 71944F106 25,704 800,000 SH   SOLE   800,000 0 0
POSEIDA THERAPEUTICS INC COM 73730P108 3,260 367,499 SH   SOLE   367,499 0 0
PPD INC COM 69355F102 19,420 525,000 SH   SOLE   525,000 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 10,855 360,263 SH   SOLE   360,263 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107 10,832 643,622 SH   SOLE   643,622 0 0
PROTHENA CORP PLC SHS G72800108 10,242 1,025,207 SH   SOLE   1,025,207 0 0
RADIUS HEALTH INC COM NEW 750469207 9,233 814,208 SH   SOLE   814,208 0 0
RADIUS HEALTH INC NOTE 3.000% 9/0 750469AA6 1,244 1,500,000 PRN   SOLE   1,500,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 17,618 413,674 SH   SOLE   413,674 0 0
RETROPHIN INC COM 761299106 18,908 1,024,261 SH   SOLE   1,024,261 0 0
RETROPHIN INC NOTE 2.500% 9/1 761299AB2 2,779 3,250,000 PRN   SOLE   3,250,000 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105 10,057 464,086 SH   SOLE   464,086 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 11,383 4,742,891 SH   SOLE   4,742,891 0 0
ROYALTY PHARMA PLC SHS CL A G7709Q104 20,404 485,000 SH   SOLE   485,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 48,519 345,500 SH   SOLE   345,500 0 0
SEATTLE GENETICS INC COM 812578102 48,923 250,000 SH   SOLE   250,000 0 0
SHOCKWAVE MED INC COM 82489T104 16,676 220,000 SH   SOLE   220,000 0 0
SPERO THERAPEUTICS INC COM 84833T103 13,797 1,236,256 SH   SOLE   1,236,256 0 0
TELEFLEX INCORPORATED COM 879369106 44,255 130,000 SH   SOLE   130,000 0 0
TG THERAPEUTICS INC COM 88322Q108 18,275 682,926 SH   SOLE   682,926 0 0
THERAVANCE BIOPHARMA INC COM G8807B106 12,183 824,018 SH   SOLE   824,018 0 0
THERAVANCE BIOPHARMA INC NOTE 3.250%11/0 88339KAA0 1,320 1,500,000 PRN   SOLE   1,500,000 0 0
TRANSLATE BIO INC COM 89374L104 8,746 642,646 SH   SOLE   642,646 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 10,955 770,918 SH   SOLE   770,918 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 47,411 576,841 SH   SOLE   576,841 0 0
UNIQURE NV SHS N90064101 15,227 413,433 SH   SOLE   413,433 0 0
UNITEDHEALTH GROUP INC COM 91324P102 126,267 405,000 SH   SOLE   405,000 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 2,449 9,000 SH   SOLE   9,000 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105 7,835 28,500 SH   SOLE   28,500 0 0
XENON PHARMACEUTICALS INC COM 98420N105 5,709 515,711 SH   SOLE   515,711 0 0
ZAI LAB LTD ADR 98887Q104 68,493 823,527 SH   SOLE   823,527 0 0
ZOGENIX INC COM NEW 98978L204 7,459 415,982 SH   SOLE   415,982 0 0