The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
1LIFE HEALTHCARE INC COM 68269G107 17,839 629,013 SH   SOLE   629,013 0 0
ABEONA THERAPEUTICS INC COM 00289Y107 1,103 1,081,388 SH   SOLE   1,081,388 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 13,506 327,415 SH   SOLE   327,415 0 0
ACCELERON PHARMA INC COM 00434H108 10,188 90,534 SH   SOLE   90,534 0 0
ACCOLADE INC COM 00437E102 1,064 27,375 SH   SOLE   27,375 0 0
ACTIVISION BLIZZARD INC COM 00507V109 88,268 1,090,403 SH   SOLE   1,090,403 0 0
ADVANCED MICRO DEVICES INC COM 007903107 15,866 193,514 SH   SOLE   193,514 0 0
AKEBIA THERAPEUTICS INC COM 00972D105 13,702 5,458,936 SH   SOLE   5,458,936 0 0
AKOUOS INC COM 00973J101 7,452 325,831 SH   SOLE   325,831 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 53,390 466,572 SH   SOLE   466,572 0 0
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102 33,871 115,217 SH   SOLE   115,217 0 0
ALKERMES PLC SHS G01767105 41,372 2,496,819 SH   SOLE   2,496,819 0 0
ALLOGENE THERAPEUTICS INC COM 019770106 15,093 400,233 SH   SOLE   400,233 0 0
ALLOVIR INC COM 019818103 32,753 1,191,014 SH   SOLE   1,191,014 0 0
ALTICE USA INC CL A 02156K103 27,300 1,049,995 SH   SOLE   1,049,995 0 0
AMAZON COM INC COM 023135106 65,604 20,835 SH   SOLE   20,835 0 0
AMBARELLA INC SHS G037AX101 9,501 182,089 SH   SOLE   182,089 0 0
AMEDISYS INC COM 023436108 14,069 59,504 SH   SOLE   59,504 0 0
AMERICAN WELL CORP CL A 03044L105 6,274 211,666 SH   SOLE   211,666 0 0
AMERISOURCEBERGEN CORP COM 03073E105 12,874 132,828 SH   SOLE   132,828 0 0
AMN HEALTHCARE SVCS INC COM 001744101 5,948 101,744 SH   SOLE   101,744 0 0
AMPHENOL CORP NEW CL A 032095101 41,831 386,358 SH   SOLE   386,358 0 0
ANALOG DEVICES INC COM 032654105 4,209 36,051 SH   SOLE   36,051 0 0
ANNEXON INC COM 03589W102 6,068 200,738 SH   SOLE   200,738 0 0
APPLIED MATLS INC COM 038222105 46,993 790,461 SH   SOLE   790,461 0 0
APTOSE BIOSCIENCES INC COM NEW 03835T200 9,794 1,632,381 SH   SOLE   1,632,381 0 0
ARCTURUS THERAPEUTICS HLDGS COM 03969T109 1,674 39,016 SH   SOLE   39,016 0 0
ARROW ELECTRS INC COM 042735100 45,043 572,625 SH   SOLE   572,625 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100 3,762 87,365 SH   SOLE   87,365 0 0
ASCENDANT DIGITAL ACQUISITIO *W EXP 07/28/202 G05155117 2,966 2,004,385 SH   SOLE   2,004,385 0 0
ASCENDANT DIGITAL ACQUISITIO COM CL A G05155109 39,847 4,008,770 SH   SOLE   4,008,770 0 0
ATHENEX INC COM 04685N103 6,050 500,000 SH   SOLE   500,000 0 0
ATHIRA PHARMA INC COM 04746L104 1,339 72,516 SH   SOLE   72,516 0 0
AVANTOR INC COM 05352A100 16,697 742,407 SH   SOLE   742,407 0 0
AVIDITY BIOSCIENCES INC COM 05370A108 4,869 172,978 SH   SOLE   172,978 0 0
AVNET INC COM 053807103 7,251 280,596 SH   SOLE   280,596 0 0
BAIDU INC SPON ADR REP A 056752108 13,867 109,546 SH   SOLE   109,546 0 0
BCTG ACQUISITION CORP COM 05492W103 5,180 500,000 SH   SOLE   500,000 0 0
BECTON DICKINSON & CO COM 075887109 11,829 50,839 SH   SOLE   50,839 0 0
BELLRING BRANDS INC COM CL A 079823100 3,054 147,234 SH   SOLE   147,234 0 0
BIOCRYST PHARMACEUTICALS INC COM 09058V103 2,984 868,708 SH   SOLE   868,708 0 0
BOWX ACQUISITION CORP UNIT 08/03/2025 103085205 8,208 800,000 SH   SOLE   800,000 0 0
BRISTOL-MYERS SQUIBB CO COM 110122108 66,545 1,103,742 SH   SOLE   1,103,742 0 0
BRISTOL-MYERS SQUIBB CO RIGHT 99/99/9999 110122157 331 146,919 SH   SOLE   146,919 0 0
CADENCE DESIGN SYSTEM INC COM 127387108 3,996 37,474 SH   SOLE   37,474 0 0
CARDINAL HEALTH INC COM 14149Y108 12,346 262,967 SH   SOLE   262,967 0 0
CHIASMA INC COM 16706W102 5,712 1,328,257 SH   SOLE   1,328,257 0 0
CHINDATA GROUP HLDGS LTD ADS 16955F107 1,136 70,000 SH   SOLE   70,000 0 0
CIENA CORP COM NEW 171779309 5,544 139,676 SH   SOLE   139,676 0 0
CIGNA CORP NEW COM 125523100 37,922 223,850 SH   SOLE   223,850 0 0
CINEMARK HLDGS INC COM 17243V102 270 26,987 SH   SOLE   26,987 0 0
CIRRUS LOGIC INC COM 172755100 9,336 138,411 SH   SOLE   138,411 0 0
COMCAST CORP NEW CL A 20030N101 9,314 201,337 SH   SOLE   201,337 0 0
COMMSCOPE HLDG CO INC COM 20337X109 4,629 514,299 SH   SOLE   514,299 0 0
COMPASS PATHWAYS PLC SPONSORED ADS 20451W101 3,593 102,944 SH   SOLE   102,944 0 0
COOPER COS INC COM NEW 216648402 13,617 40,393 SH   SOLE   40,393 0 0
COVETRUS INC COM 22304C100 5,524 226,378 SH   SOLE   226,378 0 0
CREE INC COM 225447101 7,316 114,780 SH   SOLE   114,780 0 0
CUE BIOPHARMA INC COM 22978P106 13,766 914,662 SH   SOLE   914,662 0 0
CVS HEALTH CORP COM 126650100 3,590 61,476 SH   SOLE   61,476 0 0
DANAHER CORPORATION COM 235851102 31,517 146,367 SH   SOLE   146,367 0 0
DAVITA INC COM 23918K108 4,772 55,720 SH   SOLE   55,720 0 0
DELL TECHNOLOGIES INC CL C 24703L202 3,210 47,424 SH   SOLE   47,424 0 0
DENTSPLY SIRONA INC COM 24906P109 13,031 297,979 SH   SOLE   297,979 0 0
DEXCOM INC COM 252131107 3,158 7,661 SH   SOLE   7,661 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 8,520 473,607 SH   SOLE   473,607 0 0
DIODES INC COM 254543101 14,011 248,201 SH   SOLE   248,201 0 0
DMY TECHNOLOGY GROUP INC II UNIT 99/99/9999 233277201 12,685 1,240,000 SH   SOLE   1,240,000 0 0
DRAGONEER GROWTH OPPORTUN CO UNIT 08/18/2027 G28302126 22,635 1,847,783 SH   SOLE   1,847,783 0 0
DYNE THERAPEUTICS INC COM 26818M108 5,387 266,799 SH   SOLE   266,799 0 0
ENVISTA HOLDINGS CORPORATION COM 29415F104 3,890 157,621 SH   SOLE   157,621 0 0
ERICSSON ADR B SEK 10 294821608 5,076 466,103 SH   SOLE   466,103 0 0
EURONET WORLDWIDE INC COM 298736109 15,800 173,432 SH   SOLE   173,432 0 0
EXELIXIS INC COM 30161Q104 32,076 1,311,887 SH   SOLE   1,311,887 0 0
F5 NETWORKS INC COM 315616102 8,471 68,995 SH   SOLE   68,995 0 0
FIDELITY NATL INFORMATION SV COM 31620M106 134,367 912,755 SH   SOLE   912,755 0 0
FLEX LTD ORD Y2573F102 8,689 780,000 SH   SOLE   780,000 0 0
FOX CORP CL A COM 35137L105 12,479 448,393 SH   SOLE   448,393 0 0
FREELINE THERAPEUTICS HLDGS SPONSORED ADS 35655L107 3,222 206,413 SH   SOLE   206,413 0 0
FS DEV CORP COM CL A 303020101 4,628 413,332 SH   SOLE   413,332 0 0
FUSION PHARMACEUTICALS INC COM 36118A100 915 76,093 SH   SOLE   76,093 0 0
GLOBAL PMTS INC COM 37940X102 110,033 619,625 SH   SOLE   619,625 0 0
GLU MOBILE INC COM 379890106 7,469 973,123 SH   SOLE   973,123 0 0
GOODRX HLDGS INC COM CL A 38246G108 3,475 62,500 SH   SOLE   62,500 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 8,804 90,435 SH   SOLE   90,435 0 0
HEALTH SCIENCES ACQ CORP 2 ORD SHS G4411D109 4,400 400,000 SH   SOLE   400,000 0 0
HEALTHEQUITY INC COM 42226A107 3,134 61,006 SH   SOLE   61,006 0 0
HERBALIFE NUTRITION LTD COM SHS G4412G101 1,524 32,669 SH   SOLE   32,669 0 0
HOLOGIC INC COM 436440101 20,534 308,920 SH   SOLE   308,920 0 0
HORIZON THERAPEUTICS PUB L SHS G46188101 72,678 935,603 SH   SOLE   935,603 0 0
HUMANA INC COM 444859102 22,458 54,262 SH   SOLE   54,262 0 0
ICON PLC SHS G4705A100 4,506 23,580 SH   SOLE   23,580 0 0
ICU MED INC COM 44930G107 16,862 92,263 SH   SOLE   92,263 0 0
IDEXX LABS INC COM 45168D104 25,026 63,661 SH   SOLE   63,661 0 0
IGM BIOSCIENCES INC COM 449585108 6,671 90,378 SH   SOLE   90,378 0 0
IMMATICS N.V SHS N44445109 1,980 186,591 SH   SOLE   186,591 0 0
IMMUNOVANT INC COM 45258J102 4,968 141,170 SH   SOLE   141,170 0 0
INFINERA CORP COM 45667G103 6,170 1,001,608 SH   SOLE   1,001,608 0 0
INPHI CORP COM 45772F107 24,375 217,150 SH   SOLE   217,150 0 0
INTEL CORP COM 458140100 4,443 85,814 SH   SOLE   85,814 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100 6,541 198,684 SH   SOLE   198,684 0 0
ISHARES TR RUSSELL 2000 ETF 464287655 12,166 81,218 SH   SOLE   81,218 0 0
JFROG LTD ORD SHS M6191J100 2,540 30,000 SH   SOLE   30,000 0 0
JOHNSON & JOHNSON COM 478160104 123,899 832,209 SH   SOLE   832,209 0 0
JOUNCE THERAPEUTICS INC COM 481116101 7,586 929,651 SH   SOLE   929,651 0 0
JUNIPER NETWORKS INC COM 48203R104 10,218 475,278 SH   SOLE   475,278 0 0
KADMON HLDGS INC COM 48283N106 23,043 5,878,232 SH   SOLE   5,878,232 0 0
KEYSIGHT TECHNOLOGIES INC COM 49338L103 16,861 170,689 SH   SOLE   170,689 0 0
KLA CORP COM NEW 482480100 54,923 283,490 SH   SOLE   283,490 0 0
KNOWLES CORP COM 49926D109 12,062 809,517 SH   SOLE   809,517 0 0
KYMERA THERAPEUTICS INC COM 501575104 5,370 166,217 SH   SOLE   166,217 0 0
LILLY ELI & CO COM 532457108 10,052 67,907 SH   SOLE   67,907 0 0
LUMENTUM HLDGS INC COM 55024U109 36,957 491,901 SH   SOLE   491,901 0 0
LYFT INC CL A COM 55087P104 31,055 1,127,232 SH   SOLE   1,127,232 0 0
MASTERCARD INCORPORATED CL A 57636Q104 63,426 187,557 SH   SOLE   187,557 0 0
MCKESSON CORP COM 58155Q103 9,644 64,755 SH   SOLE   64,755 0 0
MEDTRONIC PLC SHS G5960L103 44,037 423,756 SH   SOLE   423,756 0 0
MERCK & CO. INC COM 58933Y105 16,104 194,137 SH   SOLE   194,137 0 0
MICROCHIP TECHNOLOGY INC. COM 595017104 72,616 706,654 SH   SOLE   706,654 0 0
MICRON TECHNOLOGY INC COM 595112103 10,742 228,747 SH   SOLE   228,747 0 0
MOLECULAR TEMPLATES INC COM 608550109 12,130 1,110,815 SH   SOLE   1,110,815 0 0
MOLINA HEALTHCARE INC COM 60855R100 14,695 80,281 SH   SOLE   80,281 0 0
MYOKARDIA INC COM 62857M105 2,282 16,736 SH   SOLE   16,736 0 0
NETAPP INC COM 64110D104 4,963 113,217 SH   SOLE   113,217 0 0
NU SKIN ENTERPRISES INC CL A 67018T105 4,437 88,581 SH   SOLE   88,581 0 0
NURIX THERAPEUTICS INC COM 67080M103 5,030 144,087 SH   SOLE   144,087 0 0
NVIDIA CORPORATION COM 67066G104 8,120 15,003 SH   SOLE   15,003 0 0
OPEN LENDING CORP COM CL A 68373J104 9,277 363,797 SH   SOLE   363,797 0 0
ORCHARD THERAPEUTICS PLC ADS 68570P101 686 166,909 SH   SOLE   166,909 0 0
OUTSET MED INC COM 690145107 6,279 125,584 SH   SOLE   125,584 0 0
PAGSEGURO DIGITAL LTD COM CL A G68707101 8,142 215,903 SH   SOLE   215,903 0 0
PANDION THERAPEUTICS INC COM 698340106 861 75,101 SH   SOLE   75,101 0 0
PIERIS PHARMACEUTICALS INC COM 720795103 3,173 1,532,731 SH   SOLE   1,532,731 0 0
PLIANT THERAPEUTICS INC COM 729139105 3,443 152,000 SH   SOLE   152,000 0 0
PMV PHARMACEUTICALS INC COM 69353Y103 7,363 207,421 SH   SOLE   207,421 0 0
PRELUDE THERAPEUTICS INC COM 74065P101 5,404 179,361 SH   SOLE   179,361 0 0
PREVAIL THERAPEUTICS INC COM 74140Y101 3,924 385,480 SH   SOLE   385,480 0 0
PROTHENA CORP PLC SHS G72800108 1,769 177,084 SH   SOLE   177,084 0 0
PTC THERAPEUTICS INC COM 69366J200 13,680 292,610 SH   SOLE   292,610 0 0
PURE STORAGE INC CL A 74624M102 2,101 136,529 SH   SOLE   136,529 0 0
QUEST DIAGNOSTICS INC COM 74834L100 16,296 142,339 SH   SOLE   142,339 0 0
QUIDEL CORP COM 74838J101 2,116 9,645 SH   SOLE   9,645 0 0
RAPT THERAPEUTICS INC COM 75382E109 2,167 67,302 SH   SOLE   67,302 0 0
REGENXBIO INC COM 75901B107 7,580 275,442 SH   SOLE   275,442 0 0
REINVENT TECHNOLOGY PARTNERS UNIT 99/99/9999 G7483N111 13,213 1,150,000 SH   SOLE   1,150,000 0 0
RELAY THERAPEUTICS INC COM 75943R102 14,984 351,823 SH   SOLE   351,823 0 0
REVOLUTION MEDICINES INC COM 76155X100 971 27,911 SH   SOLE   27,911 0 0
RIBBIT LEAP LTD UNIT 99/99/9999 G7552B121 6,713 516,400 SH   SOLE   516,400 0 0
SAGE THERAPEUTICS INC COM 78667J108 11,315 185,134 SH   SOLE   185,134 0 0
SAVARA INC COM 805111101 647 593,594 SH   SOLE   593,594 0 0
SEATTLE GENETICS INC COM 812578102 62,129 317,487 SH   SOLE   317,487 0 0
SENSATA TECHNOLOGIES HLDNG P SHS G8060N102 8,387 194,407 SH   SOLE   194,407 0 0
SILICON LABORATORIES INC COM 826919102 6,319 64,581 SH   SOLE   64,581 0 0
SKYWORKS SOLUTIONS INC COM 83088M102 22,622 155,478 SH   SOLE   155,478 0 0
SNAP INC CL A 83304A106 38,096 1,459,062 SH   SOLE   1,459,062 0 0
SPOTIFY TECHNOLOGY S A SHS L8681T102 13,838 57,048 SH   SOLE   57,048 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107 10,601 222,376 SH   SOLE   222,376 0 0
STRYKER CORPORATION COM 863667101 35,850 172,050 SH   SOLE   172,050 0 0
SUMO LOGIC INC COM 86646P103 3,597 165,000 SH   SOLE   165,000 0 0
SURGERY PARTNERS INC COM 86881A100 3,172 144,837 SH   SOLE   144,837 0 0
SYNEOS HEALTH INC CL A 87166B102 6,013 113,119 SH   SOLE   113,119 0 0
SYNNEX CORP COM 87162W100 15,416 110,064 SH   SOLE   110,064 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109 48,504 293,570 SH   SOLE   293,570 0 0
TELEFLEX INCORPORATED COM 879369106 15,258 44,820 SH   SOLE   44,820 0 0
TERADYNE INC COM 880770102 24,124 303,605 SH   SOLE   303,605 0 0
TEXAS INSTRS INC COM 882508104 34,122 238,967 SH   SOLE   238,967 0 0
TG THERAPEUTICS INC COM 88322Q108 5,349 199,875 SH   SOLE   199,875 0 0
T-MOBILE US INC COM 872590104 36,038 315,132 SH   SOLE   315,132 0 0
TRILLIUM THERAPEUTICS INC COM NEW 89620X506 11,801 830,497 SH   SOLE   830,497 0 0
TRIPADVISOR INC COM 896945201 29,410 1,501,295 SH   SOLE   1,501,295 0 0
VESPER HEALTHCARE ACQSTN COR UNIT 99/99/9999 92538T203 20,520 2,000,000 SH   SOLE   2,000,000 0 0
VIAVI SOLUTIONS INC COM 925550105 30,180 2,572,886 SH   SOLE   2,572,886 0 0
VISHAY INTERTECHNOLOGY INC COM 928298108 50,170 3,222,196 SH   SOLE   3,222,196 0 0
ZENTALIS PHARMACEUTICALS INC COM 98943L107 4,507 137,884 SH   SOLE   137,884 0 0
ZIMMER BIOMET HOLDINGS INC COM 98956P102 31,114 228,546 SH   SOLE   228,546 0 0
ZOETIS INC CL A 98978V103 9,766 59,057 SH   SOLE   59,057 0 0
ZOGENIX INC COM NEW 98978L204 18,307 1,021,039 SH   SOLE   1,021,039 0 0
ZYMEWORKS INC COM 98985W102 19,372 415,895 SH   SOLE   415,895 0 0