The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 139,647 504,033 SH   SOLE 0 504,033 0 0
ACADIA PHARMACEUTICALS INC COM 004225108 75,582 1,832,300 SH   SOLE 0 1,832,300 0 0
AIMMUNE THERAPEUTICS INC COM 00900T107 682 19,800 SH   SOLE 0 19,800 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106 874 118,000 SH   SOLE 0 118,000 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 52,355 457,529 SH   SOLE 0 457,529 0 0
ALIGN TECHNOLOGY INC COM 016255101 22,098 67,505 SH   SOLE 0 67,505 0 0
ALIMERA SCIENCES INC COM NEW 016259202 976 200,919 SH   SOLE 0 200,919 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 28,236 3,003,875 SH   SOLE 0 3,003,875 0 0
AMICUS THERAPEUTICS INC COM 03152W109 111,084 7,867,114 SH   SOLE 0 7,867,114 0 0
ANAPTYSBIO INC COM 032724106 5,439 368,722 SH   SOLE 0 368,722 0 0
APREA THERAPEUTICS INC COM 03836J102 2,882 119,800 SH   SOLE 0 119,800 0 0
ATHENEX INC COM 04685N103 3,107 256,800 SH   SOLE 0 256,800 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 131,812 1,732,550 SH   SOLE 0 1,732,550 0 0
CLOVIS ONCOLOGY INC COM 189464100 26,057 4,469,411 SH   SOLE 0 4,469,411 0 0
CYTOKINETICS INC COM NEW 23282W605 2,678 123,686 SH   SOLE 0 123,686 0 0
DICERNA PHARMACEUTICALS INC COM 253031108 5,969 331,813 SH   SOLE 0 331,813 0 0
EHEALTH INC COM 28238P109 22,155 280,438 SH   SOLE 0 280,438 0 0
EPIZYME INC COM 29428V104 76,395 6,403,600 SH   SOLE 0 6,403,600 0 0
EVOLUS INC COM 30052C107 1,039 265,700 SH   SOLE 0 265,700 0 0
GOSSAMER BIO INC COM 38341P102 13,368 1,077,200 SH   SOLE 0 1,077,200 0 0
IDERA PHARMACEUTICALS INC COM PAR 45168K405 165 77,044 SH   SOLE 0 77,044 0 0
IMMUNOMEDICS INC COM 452907108 412,598 4,852,383 SH   SOLE 0 4,852,383 0 0
INSMED INC COM PAR $.01 457669307 193,899 6,032,956 SH   SOLE 0 6,032,956 0 0
KALEIDO BIOSCIENCES INC COM 483347100 8,705 786,400 SH   SOLE 0 786,400 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106 74,258 5,086,152 SH   SOLE 0 5,086,152 0 0
KEZAR LIFE SCIENCES INC COM 49372L100 2,368 489,319 SH   SOLE 0 489,319 0 0
MAGENTA THERAPEUTICS INC COM 55910K108 2,337 343,700 SH   SOLE 0 343,700 0 0
MARINUS PHARMACEUTICALS INC COM 56854Q101 403 31,330 SH   SOLE 0 31,330 0 0
MINERVA NEUROSCIENCES INC COM 603380106 115 36,319 SH   SOLE 0 36,319 0 0
PROTHENA CORP PLC SHS G72800108 13,274 1,328,734 SH   SOLE 0 1,328,734 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 13,806 1,368,317 SH   SOLE 0 1,368,317 0 0
RETROPHIN INC COM 761299106 2,915 157,900 SH   SOLE 0 157,900 0 0
REVANCE THERAPEUTICS INC COM 761330109 50,152 1,994,905 SH   SOLE 0 1,994,905 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 2,842 1,184,092 SH   SOLE 0 1,184,092 0 0
SAGE THERAPEUTICS INC COM 78667J108 36,073 590,200 SH   SOLE 0 590,200 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 157,898 2,791,693 SH   SOLE 0 2,791,693 0 0
SUNESIS PHARMACEUTICALS INC COM 867328700 145 116,246 SH   SOLE 0 116,246 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105 2,928 198,400 SH   SOLE 0 198,400 0 0
TRICIDA INC COM 89610F101 1,547 170,800 SH   SOLE 0 170,800 0 0
UNITED THERAPEUTICS CORP COM 91307C102 79,326 785,406 SH   SOLE 0 785,406 0 0
UROGEN PHARMA LTD COM M96088105 473 24,500 SH   SOLE 0 24,500 0 0
VANDA PHARMACEUTICALS INC COM 921659108 40,285 4,170,281 SH   SOLE 0 4,170,281 0 0
ZOGENIX INC COM NEW 98978L204 2,933 163,600 SH   SOLE 0 163,600 0 0